{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T05:14:05Z","timestamp":1769577245209,"version":"3.49.0"},"reference-count":16,"publisher":"The Endocrine Society","issue":"2","license":[{"start":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T00:00:00Z","timestamp":1769472000000},"content-version":"vor","delay-in-days":19,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Endocrinology Training Grant","award":["T32DK007217"],"award-info":[{"award-number":["T32DK007217"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Pseudopheochromocytoma is a disorder characterized by paroxysmal hypertension and variably elevated catecholamine metabolite levels. Pseudopheochromocytoma clinically mimics pheochromocytoma but differs in etiology. While pheochromocytoma is a catecholamine-secreting neuroendocrine tumor, pseudopheochromocytoma is a syndrome linked to a history of emotional stressors and is believed to stem from autonomic nervous system dysregulation. We present the case of a 70-year-old female patient experiencing episodic hypertensive crises for 3 decades. The patient was referred to endocrine oncology for evaluation of a possible pheochromocytoma due to her long-standing history of symptomatic hypertension and elevated catecholamine metabolites. Anatomic and functional imaging, including computed tomography scans of the abdomen and pelvis and a 64Copper-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid-octreotate positron emission tomography computed tomography excluded a diagnosis of pheochromocytoma or paraganglioma. Her history of significant emotional stressors raised the possibility of pseudopheochromocytoma. Following initiation of escitalopram and psychotherapy, the patient experienced a remarkable improvement in the frequency and severity of hypertensive episodes. This case illustrates the diagnostic challenges of pseudopheochromocytoma and the importance of early intervention in preventing complications.<\/jats:p>","DOI":"10.1210\/jcemcr\/luaf321","type":"journal-article","created":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T12:53:04Z","timestamp":1765025584000},"source":"Crossref","is-referenced-by-count":0,"title":["Pseudopheochromocytoma With Catecholamine Excess and End-organ Damage: A 30-year Course Treated With Escitalopram"],"prefix":"10.1210","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-5984-8414","authenticated-orcid":false,"given":"Ayli S","family":"Anvaripour","sequence":"first","affiliation":[{"name":"Indiana University School of Medicine , Indianapolis, IN 46202 ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-5637-5591","authenticated-orcid":false,"given":"Leor","family":"Needleman","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Endocrinology, Gerontology and Metabolism and Endocrine Oncology, Stanford University , Stanford, CA 94305 ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian","family":"Brady","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Nephrology, Stanford University School of Medicine , Stanord, CA 94305 ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8431-3589","authenticated-orcid":false,"given":"Justin P","family":"Annes","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Endocrinology, Gerontology and Metabolism and Endocrine Oncology, Stanford University , Stanford, CA 94305 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