{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T03:40:26Z","timestamp":1792640426337,"version":"4.5.0"},"reference-count":24,"publisher":"The Endocrine Society","issue":"6","license":[{"start":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T00:00:00Z","timestamp":1778025600000},"content-version":"vor","delay-in-days":7,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,4,29]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Papillary thyroid carcinoma (PTC) is the most prevalent form of thyroid malignancy. Although it carries a favorable prognosis, especially for individuals under the age of 45, tumor recurrences in the thyroid bed still occur. In fact, recurrence rates are observed in approximately 20% of patients following initial treatment. For patients who are not candidates for surgery or radioactive iodine therapy, ethanol ablation is a treatment option for recurrences in the thyroid bed and lymph node metastases. This case report details a 31-year-old female patient with a PTC who underwent total thyroidectomy and radioactive iodine therapy. One year later, a locoregional recurrence developed in the thyroid bed. The recurrence was determined to be iodine-refractory, and due to its size and the patient's preference, surgery was not an option; hence ethanol ablation was performed. After the ethanol ablation procedure, the patient exhibited left eyelid drooping. She was diagnosed with Horner syndrome characterized by left upper eyelid ptosis, myosis, and anhidrosis. Although uncommon, Horner syndrome should still be considered as a potential postoperative complication in patients undergoing ethanol ablation for locoregional recurrence of PTC.<\/jats:p>","DOI":"10.1210\/jcemcr\/luag085","type":"journal-article","created":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T12:13:44Z","timestamp":1773404024000},"source":"Crossref","is-referenced-by-count":1,"title":["Horner syndrome after ethanol ablation for radioactive iodine therapy refractory papillary thyroid carcinoma"],"prefix":"10.1210","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-3796-5737","authenticated-orcid":false,"given":"Fidela Anne","family":"Badilles","sequence":"first","affiliation":[{"name":"Center for Diabetes, Thyroid, and Endocrine Disorders, St. Luke\u2019s Medical Center , Global City 1634 ,","place":["Philippines"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0181-3719","authenticated-orcid":false,"given":"Michael","family":"Villa","sequence":"additional","affiliation":[{"name":"Center for Diabetes, Thyroid, and Endocrine Disorders, St. Luke\u2019s Medical Center , Global City 1634 ,","place":["Philippines"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","published-online":{"date-parts":[[2026,5,6]]},"reference":[{"issue":"1","key":"2026052009463693100_luag085-B1","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/s12022-022-09707-3","article-title":"Overview of the 2022 WHO classification of thyroid neoplasms","volume":"33","author":"Baloch","year":"2022","journal-title":"Endocr Pathol"},{"issue":"2","key":"2026052009463693100_luag085-B2","first-page":"e140","article-title":"Horner syndrome after percutaneous ethanol injection for treatment of metastatic papillary thyroid carcinoma: case report and review of the literature","volume":"3","author":"Hussain Ahmed","year":"2017","journal-title":"AACE Clin Case Rep"},{"issue":"5","key":"2026052009463693100_luag085-B3","doi-asserted-by":"crossref","first-page":"e2141","DOI":"10.1210\/clinem\/dgab907","article-title":"Long-term efficacy of ethanol ablation as treatment of metastatic lymph nodes from papillary thyroid carcinoma","volume":"107","author":"Frich","year":"2022","journal-title":"J Clin Endocrinol Metab"},{"key":"2026052009463693100_luag085-B4","volume-title":"Williams Textbook of Endocrinology","author":"Melmed","year":"2025","edition":"15"},{"issue":"1","key":"2026052009463693100_luag085-B5","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.surg.2017.05.028","article-title":"Back so soon? Is early recurrence of papillary thyroid cancer really just persistent disease?","volume":"163","author":"Bates","year":"2018","journal-title":"Surgery"},{"issue":"1","key":"2026052009463693100_luag085-B6","doi-asserted-by":"crossref","first-page":"100","DOI":"10.15605\/jafes.038.01.14","article-title":"Incidence, recurrence and mortality among Filipinos with differentiated thyroid cancer: a systematic review","volume":"38","author":"San Juan","year":"2023","journal-title":"J ASEAN Fed Endocr Soc"},{"issue":"1","key":"2026052009463693100_luag085-B7","doi-asserted-by":"crossref","first-page":"72","DOI":"10.3803\/EnM.2016.31.1.72","article-title":"Well-differentiated thyroid cancer: the Philippine General Hospital experience","volume":"31","author":"Lo","year":"2016","journal-title":"Endocrinol Metab (Seoul)"},{"issue":"6","key":"2026052009463693100_luag085-B8","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1001\/jamaoto.2015.0596","article-title":"Percutaneous ethanol 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Radiol"},{"issue":"4","key":"2026052009463693100_luag085-B14","doi-asserted-by":"crossref","first-page":"380","DOI":"10.21053\/ceo.2023.00689","article-title":"Ultrasound-guided ethanol percutaneous ablation versus rescue surgery in patients with locoregional recurrence of papillary thyroid cancer","volume":"16","author":"Tof\u00e9","year":"2023","journal-title":"Clin Exp Otorhinolaryngol"},{"issue":"3","key":"2026052009463693100_luag085-B15","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1089\/thy.2010.0386","article-title":"Horner's syndrome as a complication of percutaneous ethanol treatment of thyroid nodule","volume":"21","author":"Pishdad","year":"2011","journal-title":"Thyroid"},{"issue":"1","key":"2026052009463693100_luag085-B16","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1136\/bjo.82.1.51","article-title":"Does Horner's syndrome in infancy require investigation?","volume":"82","author":"George","year":"1998","journal-title":"Br J 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therapy","volume":"154","author":"Hay","year":"2013","journal-title":"Surgery"},{"issue":"1","key":"2026052009463693100_luag085-B23","first-page":"111","article-title":"Horner's syndrome: an uncommon complication of thyroidectomy and selective lateral neck dissection","volume":"45","author":"Sapalidis","year":"2019","journal-title":"Curr Health Sci J"},{"issue":"1","key":"2026052009463693100_luag085-B24","doi-asserted-by":"crossref","first-page":"108","DOI":"10.21037\/gs-22-568","article-title":"A clinical practice review of percutaneous ethanol injection for thyroid nodules: state of the art for benign, cystic lesions","volume":"13","author":"Clark","year":"2024","journal-title":"Gland Surg"}],"container-title":["JCEM Case 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