{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T02:25:49Z","timestamp":1783477549717,"version":"3.55.0"},"reference-count":42,"publisher":"The Endocrine Society","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Context<\/jats:title>\n                  <jats:p>Cushing syndrome (CS) is associated with impaired health-related quality of life (HRQOL) even after surgical cure.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>To characterize patient and provider perspectives on recovery from CS, drivers of decreased HRQOL during recovery, and ways to improve HRQOL.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Design<\/jats:title>\n                  <jats:p>Cross-sectional observational survey.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Participants<\/jats:title>\n                  <jats:p>Patients (n\u2005=\u2005341) had undergone surgery for CS and were members of the Cushing\u2019s Support and Research Foundation. Physicians (n\u2005=\u200554) were Pituitary Society physician members and academicians who treated patients with CS.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Compared with patients, physicians underestimated the time to complete recovery after surgery (12 months vs 18 months, P\u2005=\u20050.0104). Time to recovery did not differ by CS etiology, but patients with adrenal etiologies of CS reported a longer duration of cortisol replacement medication compared with patients with Cushing disease (12 months vs 6 months, P\u2005=\u20050.0025). Physicians overestimated the benefits of work (26.9% vs 65.3%, P\u2005&amp;lt;\u20050.0001), exercise (40.9% vs 77.6%, P\u2005=\u20050.0001), and activities (44.8% vs 75.5%, P\u2005=\u20050.0016) as useful coping mechanisms in the postsurgical period. Most patients considered family\/friends (83.4%) and rest (74.7%) to be helpful. All physicians endorsed educating patients on recovery, but 32.4% (95% CI, 27.3-38.0) of patients denied receiving sufficient information. Some patients did not feel prepared for the postsurgical experience (32.9%; 95% CI, 27.6-38.6) and considered physicians not familiar enough with CS (16.1%; 95% CI, 12.2-20.8).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Poor communication between physicians and CS patients may contribute to dissatisfaction with the postsurgical experience. Increased information on recovery, including helpful coping mechanisms, and improved provider-physician communication may improve HRQOL during recovery.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1210\/jendso\/bvab109","type":"journal-article","created":{"date-parts":[[2021,6,14]],"date-time":"2021-06-14T17:48:50Z","timestamp":1623692930000},"source":"Crossref","is-referenced-by-count":22,"title":["Patient and Provider Perspectives on Postsurgical Recovery of Cushing Syndrome"],"prefix":"10.1210","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7512-357X","authenticated-orcid":false,"given":"Rachel","family":"Acree","sequence":"first","affiliation":[{"name":"Diabetes, Endocrinology and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, 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