{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T14:18:29Z","timestamp":1793110709139,"version":"4.5.0"},"reference-count":46,"publisher":"The Endocrine Society","issue":"10","license":[{"start":{"date-parts":[[2021,7,12]],"date-time":"2021-07-12T00:00:00Z","timestamp":1626048000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>We report on a case of a 50-year-old female patient with primary hyperaldosteronism, in whom adrenal venous sampling was required to differentiate between unilateral and bilateral disease. Because of a history of severe allergy to iodinated contrast media, premedication with glucocorticoids was indicated. Exogenous glucocorticoids, however, can affect measurements of serum cortisol. To avoid this potential confounding effects on the cortisol assay, we decided to use dexamethasone instead of prednisolone or hydrocortisone. A high-dose adrenocorticotropin (ACTH) stimulation test with the simultaneous use of dexamethasone revealed an adequate adrenal cortisol response. ACTH-stimulated adrenal venous sampling showed reliable results, which provided a solid basis for further clinical decision-making.<\/jats:p>","DOI":"10.1210\/jendso\/bvab122","type":"journal-article","created":{"date-parts":[[2021,7,12]],"date-time":"2021-07-12T15:31:38Z","timestamp":1626103898000},"source":"Crossref","is-referenced-by-count":7,"title":["Adrenal Vein Sampling in a Patient With Primary Hyperaldosteronism and Severe Contrast Allergy"],"prefix":"10.1210","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9788-425X","authenticated-orcid":false,"given":"Margaretha L M","family":"Prins","sequence":"first","affiliation":[{"name":"Department of Medicine, Leiden University Medical Centre, Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8928-3849","authenticated-orcid":false,"given":"Bartholomeus E P B","family":"Ballieux","sequence":"additional","affiliation":[{"name":"Department of Clinical Chemistry and Laboratory Medicine, Leiden University Medical Centre, Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8394-6859","authenticated-orcid":false,"given":"Onno C","family":"Meijer","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Endocrinology, Leiden University Medical Centre, Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1194-9866","authenticated-orcid":false,"given":"Alberto M","family":"Pereira","sequence":"additional","affiliation":[{"name":"Department of Medicine, Leiden University Medical Centre, Leiden, The Netherlands"},{"name":"Department of Medicine, Division of Endocrinology, Leiden University Medical Centre, Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5131-2237","authenticated-orcid":false,"given":"Michiel F","family":"Nijhoff","sequence":"additional","affiliation":[{"name":"Department of Medicine, Leiden University Medical Centre, Leiden, The Netherlands"},{"name":"Department of Medicine, Division of Endocrinology, Leiden University Medical Centre, Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","published-online":{"date-parts":[[2021,7,12]]},"reference":[{"issue":"1","key":"2021110515294775100_CIT0001","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1001\/archinternmed.2007.33","article-title":"Cardiovascular outcomes in patients with primary aldosteronism after treatment","volume":"168","author":"Catena","year":"2008","journal-title":"Arch Intern Med."},{"issue":"3","key":"2021110515294775100_CIT0002","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.tem.2005.02.010","article-title":"Aldosterone as a cardiovascular risk factor","volume":"16","author":"Rossi","year":"2005","journal-title":"Trends Endocrinol Metab."},{"issue":"4","key":"2021110515294775100_CIT0003","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1161\/HYPERTENSIONAHA.117.10596","article-title":"Adrenalectomy lowers incident atrial fibrillation in primary aldosteronism patients at long term","volume":"71","author":"Rossi","year":"2018","journal-title":"Hypertension."},{"issue":"3","key":"2021110515294775100_CIT0004","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.tem.2008.01.006","article-title":"Primary aldosteronism: cardiovascular, renal and metabolic implications","volume":"19","author":"Rossi","year":"2008","journal-title":"Trends Endocrinol Metab."},{"issue":"1","key":"2021110515294775100_CIT0005","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1161\/HYPERTENSIONAHA.113.01316","article-title":"Long-term control of arterial hypertension and regression of left ventricular hypertrophy with treatment of primary aldosteronism","volume":"62","author":"Rossi","year":"2013","journal-title":"Hypertension."},{"issue":"8","key":"2021110515294775100_CIT0006","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1016\/j.jacc.2005.01.015","article-title":"Evidence for an increased rate of cardiovascular events in patients with primary aldosteronism","volume":"45","author":"Milliez","year":"2005","journal-title":"J Am Coll Cardiol."},{"issue":"12","key":"2021110515294775100_CIT0007","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1038\/ajh.2010.169","article-title":"Cardiovascular and renal damage in primary aldosteronism: outcomes after treatment","volume":"23","author":"Sechi","year":"2010","journal-title":"Am J Hypertens."},{"issue":"12","key":"2021110515294775100_CIT0008","doi-asserted-by":"crossref","first-page":"4826","DOI":"10.1210\/jc.2013-2805","article-title":"Long-term cardio- and cerebrovascular events in patients with primary aldosteronism","volume":"98","author":"Mulatero","year":"2013","journal-title":"J Clin Endocrinol Metab."},{"issue":"2","key":"2021110515294775100_CIT0009","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1161\/HYPERTENSIONAHA.113.01060","article-title":"Cardiovascular complications associated with primary aldosteronism: a controlled cross-sectional study","volume":"62","author":"Savard","year":"2013","journal-title":"Hypertension."},{"issue":"6","key":"2021110515294775100_CIT0010","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1055\/s-0029-1246185","article-title":"Mineralocorticoid antagonists treatment versus surgery in primary aldosteronism","volume":"42","author":"Catena","year":"2010","journal-title":"Horm Metab Res."},{"issue":"9","key":"2021110515294775100_CIT0011","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/S2213-8587(16)30100-0","article-title":"Adrenal vein sampling versus CT scan to determine treatment in primary aldosteronism: an outcome-based randomised diagnostic trial","volume":"4","author":"Dekkers","year":"2016","journal-title":"Lancet Diabetes Endocrinol."},{"issue":"9","key":"2021110515294775100_CIT0012","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/S2213-8587(17)30135-3","article-title":"Outcomes after adrenalectomy for unilateral primary aldosteronism: an international consensus on outcome measures and analysis of remission rates in an international cohort","volume":"5","author":"Williams","year":"2017","journal-title":"Lancet Diabetes Endocrinol."},{"issue":"5","key":"2021110515294775100_CIT0013","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1161\/HYPERTENSIONAHA.107.095448","article-title":"Long-term cardiac effects of adrenalectomy or mineralocorticoid antagonists in patients with primary aldosteronism","volume":"50","author":"Catena","year":"2007","journal-title":"Hypertension."},{"issue":"1","key":"2021110515294775100_CIT0014","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S2213-8587(17)30367-4","article-title":"Cardiometabolic outcomes and mortality in medically treated primary aldosteronism: a retrospective cohort study","volume":"6","author":"Hundemer","year":"2018","journal-title":"Lancet Diabetes Endocrinol."},{"issue":"3","key":"2021110515294775100_CIT0015","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1161\/HYPERTENSIONAHA.112.197111","article-title":"Observational study mortality in treated primary aldosteronism: the German Conn\u2019s registry","volume":"60","author":"Reincke","year":"2012","journal-title":"Hypertension."},{"issue":"4","key":"2021110515294775100_CIT0016","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1002\/bjs.9744","article-title":"Systematic review of surgery and outcomes in patients with primary aldosteronism","volume":"102","author":"Muth","year":"2015","journal-title":"Br J Surg."},{"issue":"5","key":"2021110515294775100_CIT0017","doi-asserted-by":"crossref","first-page":"1889","DOI":"10.1210\/jc.2015-4061","article-title":"The management of primary aldosteronism: case detection, diagnosis, and treatment: an endocrine society clinical practice guideline","volume":"101","author":"Funder","year":"2016","journal-title":"J Clin Endocrinol Metab."},{"issue":"14","key":"2021110515294775100_CIT0018","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1056\/NEJM198710013171401","article-title":"Pretreatment with corticosteroids to alleviate reactions to intravenous contrast material","volume":"317","author":"Lasser","year":"1987","journal-title":"N Engl J Med."},{"issue":"6","key":"2021110515294775100_CIT0019","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1515\/cclm-2016-0400","article-title":"Multicenter performance evaluation of a second generation cortisol assay","volume":"55","author":"Vogeser","year":"2017","journal-title":"Clin Chem Lab Med."},{"key":"2021110515294775100_CIT0020"},{"issue":"6","key":"2021110515294775100_CIT0021","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1016\/j.surg.2004.06.051","article-title":"Role for adrenal venous sampling in primary aldosteronism","volume":"136","author":"Young","year":"2004","journal-title":"Surgery."},{"issue":"6","key":"2021110515294775100_CIT0022","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.2214\/ajr.176.6.1761385","article-title":"Trends in adverse events after IV administration of contrast media","volume":"176","author":"Cochran","year":"2001","journal-title":"AJR Am J Roentgenol."},{"issue":"2","key":"2021110515294775100_CIT0023","doi-asserted-by":"crossref","first-page":"409","DOI":"10.2214\/AJR.07.3421","article-title":"Frequency, outcome, and appropriateness of treatment of nonionic iodinated contrast media reactions","volume":"191","author":"Wang","year":"2008","journal-title":"AJR Am J Roentgenol."},{"issue":"1","key":"2021110515294775100_CIT0024","doi-asserted-by":"crossref","first-page":"31","DOI":"10.2214\/ajr.184.1.01840031","article-title":"Universal use of nonionic iodinated contrast medium for CT: evaluation of safety in a large urban teaching hospital","volume":"184","author":"Mortel\u00e9","year":"2005","journal-title":"AJR Am J Roentgenol."},{"issue":"4","key":"2021110515294775100_CIT0025","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.2214\/AJR.09.2520","article-title":"Frequency and severity of adverse effects of iodinated and gadolinium contrast materials: retrospective review of 456,930 doses","volume":"193","author":"Hunt","year":"2009","journal-title":"AJR Am J Roentgenol."},{"key":"2021110515294775100_CIT0026","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/1472-6947-13-18","article-title":"Risk factors for adverse reactions from contrast agents for computed tomography","volume":"13","author":"Kobayashi","year":"2013","journal-title":"BMC Med Inform Decis Mak."},{"issue":"9","key":"2021110515294775100_CIT0027","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1097\/RLI.0000000000000568","article-title":"Acute adverse reactions to nonionic iodinated contrast media: a meta-analysis","volume":"54","author":"Suh","year":"2019","journal-title":"Invest Radiol."},{"issue":"1","key":"2021110515294775100_CIT0028","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1148\/radiol.2019190485","article-title":"Hypersensitivity reactions to iodinated contrast media: a multicenter study of 196 081 patients","volume":"293","author":"Cha","year":"2019","journal-title":"Radiology."},{"issue":"7","key":"2021110515294775100_CIT0029","doi-asserted-by":"crossref","first-page":"2886","DOI":"10.1007\/s00330-016-4682-y","article-title":"Re-exposure to low osmolar iodinated contrast media in patients with prior moderate-to-severe hypersensitivity reactions: a multicentre retrospective cohort study","volume":"27","author":"Park","year":"2017","journal-title":"Eur Radiol."},{"issue":"9","key":"2021110515294775100_CIT0030","doi-asserted-by":"crossref","first-page":"1942","DOI":"10.1097\/HJH.0000000000001827","article-title":"Adrenal venous sampling in dye-allergic primary aldosteronism patients: prevalence, pitfalls and a possible solution","volume":"36","author":"Battistel","year":"2018","journal-title":"J Hypertens."},{"issue":"3","key":"2021110515294775100_CIT0031","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1148\/radiology.183.3.1584929","article-title":"Late adverse reactions to nonionic contrast media","volume":"183","author":"Yoshikawa","year":"1992","journal-title":"Radiology."},{"issue":"6","key":"2021110515294775100_CIT0032","doi-asserted-by":"crossref","first-page":"444","DOI":"10.18176\/jiaci.0374","article-title":"Incidence and risk factors of immediate hypersensitivity reactions associated with low-osmolar iodinated contrast media: a longitudinal study based on a real-time monitoring system","volume":"29","author":"Lee","year":"2019","journal-title":"J Investig Allergol Clin Immunol."},{"issue":"5","key":"2021110515294775100_CIT0033","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1177\/152660280200900514","article-title":"Gadodiamide as an alternative contrast agent during angioplasty in patients with contraindications to iodinated media","volume":"9","author":"Zeller","year":"2002","journal-title":"J Endovasc Ther."},{"issue":"6","key":"2021110515294775100_CIT0034","doi-asserted-by":"crossref","first-page":"1613","DOI":"10.2214\/ajr.172.6.10350300","article-title":"Selective angiography of the common carotid artery with gadopentetate dimeglumine in a patient with renal insufficiency","volume":"172","author":"Kaufman","year":"1999","journal-title":"AJR Am J Roentgenol."},{"issue":"2","key":"2021110515294775100_CIT0035","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1111\/j.1540-8183.2007.00340.x","article-title":"Gadolinium-based coronary angiography in patients with contraindication for iodinated x-ray contrast medium: a word of caution","volume":"21","author":"K\u00e4lsch","year":"2008","journal-title":"J Interv Cardiol."},{"issue":"5","key":"2021110515294775100_CIT0036","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1507\/endocrj.51.487","article-title":"Use of gadolinium contrast adrenal venography for the assessment of primary aldosteronism in a patient with iodine allergy","volume":"51","author":"Sasamura","year":"2004","journal-title":"Endocr J."},{"issue":"4","key":"2021110515294775100_CIT0037","doi-asserted-by":"crossref","first-page":"715","DOI":"10.2214\/AJR.17.18655","article-title":"Reactions to both nonionic iodinated and gadolinium-based contrast media: incidence and clinical characteristics","volume":"210","author":"Sodagari","year":"2018","journal-title":"AJR Am J Roentgenol."},{"issue":"2","key":"2021110515294775100_CIT0038","doi-asserted-by":"crossref","first-page":"e23","DOI":"10.1016\/j.ijcard.2011.09.022","article-title":"Adrenal venous sampling by using gadopentetate dimeglumine in patients with contraindications for iodinated contrast agents","volume":"157","author":"Mitsuba","year":"2012","journal-title":"Int J Cardiol."},{"issue":"3","key":"2021110515294775100_CIT0039","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/S1051-0443(97)70577-3","article-title":"CO2 digital subtraction angiography: potential complications and their prevention","volume":"8","author":"Caridi","year":"1997","journal-title":"J Vasc Interv Radiol."},{"issue":"11","key":"2021110515294775100_CIT0040","doi-asserted-by":"crossref","first-page":"2711","DOI":"10.1210\/me.2005-0461","article-title":"Reciprocal regulation of a glucocorticoid receptor-steroidogenic factor-1 transcription complex on the Dax-1 promoter by glucocorticoids and adrenocorticotropic hormone in the adrenal cortex","volume":"20","author":"Gummow","year":"2006","journal-title":"Mol Endocrinol."},{"issue":"2","key":"2021110515294775100_CIT0041","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1210\/jc.2015-1710","article-title":"Diagnosis and treatment of primary adrenal insufficiency: an endocrine society clinical practice guideline","volume":"101","author":"Bornstein","year":"2016","journal-title":"J Clin Endocrinol Metab."},{"issue":"5","key":"2021110515294775100_CIT0042","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1111\/cen.12039","article-title":"Method-specific serum cortisol responses to the adrenocorticotrophin test: comparison of gas chromatography-mass spectrometry and five automated immunoassays","volume":"78","author":"El-Farhan","year":"2013","journal-title":"Clin Endocrinol."},{"issue":"4","key":"2021110515294775100_CIT0043","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/j.ecl.2019.08.012","article-title":"Adrenal venous sampling: where do we stand?","volume":"48","author":"Rossi","year":"2019","journal-title":"Endocrinol Metab Clin North Am."},{"issue":"3","key":"2021110515294775100_CIT0044","first-page":"1066","article-title":"Comparison of adrenal vein sampling and computed tomography in the differentiation of primary aldosteronism","volume":"86","author":"Magill","year":"2001","journal-title":"J Clin Endocrinol Metab."},{"issue":"8","key":"2021110515294775100_CIT0045","doi-asserted-by":"crossref","first-page":"3637","DOI":"10.1210\/jc.2002-022051","article-title":"Predicting surgically remedial primary aldosteronism: role of adrenal scanning, posture testing, and adrenal vein sampling","volume":"88","author":"Espiner","year":"2003","journal-title":"J Clin Endocrinol Metab."},{"issue":"3","key":"2021110515294775100_CIT0046","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1148\/radiology.184.3.1509049","article-title":"Distinction between hyperaldosteronism due to bilateral hyperplasia and unilateral aldosteronoma: reliability of CT","volume":"184","author":"Doppman","year":"1992","journal-title":"Radiology."}],"container-title":["Journal of the Endocrine Society"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jes\/advance-article-pdf\/doi\/10.1210\/jendso\/bvab122\/38917375\/bvab122.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jes\/article-pdf\/5\/10\/bvab122\/41090705\/bvab122.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jes\/article-pdf\/5\/10\/bvab122\/41090705\/bvab122.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,5]],"date-time":"2021-11-05T15:30:16Z","timestamp":1636126216000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jes\/article\/doi\/10.1210\/jendso\/bvab122\/6319398"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,12]]},"references-count":46,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2021,10,1]]}},"URL":"https:\/\/doi.org\/10.1210\/jendso\/bvab122","relation":{},"ISSN":["2472-1972"],"issn-type":[{"value":"2472-1972","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2021,10,1]]},"published":{"date-parts":[[2021,7,12]]},"article-number":"bvab122"}}