{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T12:14:09Z","timestamp":1783599249381,"version":"3.55.0"},"reference-count":208,"publisher":"The Endocrine Society","issue":"6","license":[{"start":{"date-parts":[[2022,4,22]],"date-time":"2022-04-22T00:00:00Z","timestamp":1650585600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["T32 HD041921"],"award-info":[{"award-number":["T32 HD041921"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P50 HD044405"],"award-info":[{"award-number":["P50 HD044405"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P50 HD102172"],"award-info":[{"award-number":["P50 HD102172"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R25 GM083252"],"award-info":[{"award-number":["R25 GM083252"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P51 OD011106"],"award-info":[{"award-number":["P51 OD011106"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Context<\/jats:title>\n                  <jats:p>Ovarian estradiol supports female sexual behavior and metabolic function. While ovariectomy (OVX) in rodents abolishes sexual behavior and enables obesity, OVX in nonhuman primates decreases, but does not abolish, sexual behavior, and inconsistently alters weight gain.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>We hypothesize that extra-ovarian estradiol provides key support for both functions, and to test this idea, we employed aromatase inhibition to eliminate extra-ovarian estradiol biosynthesis and diet-induced obesity to enhance weight gain.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Thirteen adult female marmosets were OVX and received (1) estradiol-containing capsules and daily oral treatments of vehicle (E2; n\u2005=\u20055); empty capsules and daily oral treatments of either (2) vehicle (VEH, 1 mL\/kg, n\u2005=\u20054), or (3) letrozole (LET, 1 mg\/kg, n\u2005=\u20054).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>After 7 months, we observed robust sexual receptivity in E2, intermediate frequencies in VEH, and virtually none in LET females (P\u2005=\u2005.04). By contrast, few rejections of male mounts were observed in E2, intermediate frequencies in VEH, and high frequencies in LET females (P\u2005=\u2005.04). Receptive head turns were consistently observed in E2, but not in VEH and LET females. LET females, alone, exhibited robust aggressive rejection of males. VEH and LET females demonstrated increased % body weight gain (P\u2005=\u2005.01). Relative estradiol levels in peripheral serum were E2 &amp;gt;&amp;gt;&amp;gt; VEH\u2005&amp;gt;\u2005LET, while those in hypothalamus ranked E2\u2005=\u2005VEH\u2005&amp;gt;\u2005LET, confirming inhibition of local hypothalamic estradiol synthesis by letrozole.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Our findings provide the first evidence for extra-ovarian estradiol contributing to female sexual behavior in a nonhuman primate, and prompt speculation that extra-ovarian estradiol, and in particular neuroestrogens, may similarly regulate sexual motivation in other primates, including humans.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1210\/jendso\/bvac063","type":"journal-article","created":{"date-parts":[[2022,4,22]],"date-time":"2022-04-22T04:01:21Z","timestamp":1650600081000},"source":"Crossref","is-referenced-by-count":4,"title":["Aromatase Inhibition Eliminates Sexual Receptivity Without Enhancing Weight Gain in Ovariectomized Marmoset Monkeys"],"prefix":"10.1210","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8612-401X","authenticated-orcid":false,"given":"Marissa","family":"Kraynak","sequence":"first","affiliation":[{"name":"Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA"},{"name":"Endocrinology-Reproductive Physiology Training Program, University of Wisconsin-Madison, Madison, WI 53715, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2295-5102","authenticated-orcid":false,"given":"Molly M","family":"Willging","sequence":"additional","affiliation":[{"name":"Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA"},{"name":"Endocrinology-Reproductive Physiology Training Program, University of Wisconsin-Madison, Madison, WI 53715, USA"},{"name":"Center for Women\u2019s Health, University of Wisconsin-Madison, Madison, WI 53715, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex L","family":"Kuehlmann","sequence":"additional","affiliation":[{"name":"Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amita A","family":"Kapoor","sequence":"additional","affiliation":[{"name":"Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2227-913X","authenticated-orcid":false,"given":"Matthew T","family":"Flowers","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Wisconsin-Madison, Madison, WI 53715, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9706-0525","authenticated-orcid":false,"given":"Ricki 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USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8249-263X","authenticated-orcid":false,"given":"David H","family":"Abbott","sequence":"additional","affiliation":[{"name":"Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA"},{"name":"Endocrinology-Reproductive Physiology Training Program, University of Wisconsin-Madison, Madison, WI 53715, USA"},{"name":"Department of Obstetrics and Gynecology, University of Wisconsin-Madison, Madison, WI 53715, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","published-online":{"date-parts":[[2022,4,22]]},"reference":[{"issue":"4-6","key":"2022051715484365600_CIT0001","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/0039-128X(87)90036-5","article-title":"Aromatase activity in the breast and other peripheral tissues and its therapeutic 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Med."},{"issue":"7","key":"2022051715484365600_CIT0100","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/07420528.2020.1773495","article-title":"Aging-related changes on social synchronization of circadian activity rhythm in a diurnal primate (Callithrix jacchus)","volume":"37","author":"Gon\u00e7alves","year":"2020","journal-title":"Chronobiol Int."},{"key":"2022051715484365600_CIT0101","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1111\/j.1749-6632.1998.tb10559.x","article-title":"Behavioral and single chorda tympani taste fiber responses in the common marmoset, Callithrix jacchus jacchus","volume":"855","author":"Danilova","year":"1998","journal-title":"Ann N Y Acad Sci."},{"issue":"2","key":"2022051715484365600_CIT0102","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1152\/jn.2002.88.2.579","article-title":"Sense of taste in a new world monkey, the common marmoset: recordings from the chorda tympani and glossopharyngeal 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