{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T16:11:30Z","timestamp":1785514290468,"version":"3.56.0"},"reference-count":17,"publisher":"The Endocrine Society","issue":"10","license":[{"start":{"date-parts":[[2022,8,16]],"date-time":"2022-08-16T00:00:00Z","timestamp":1660608000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Context<\/jats:title>\n                  <jats:p>The 2012 Endocrine Society Clinical Practice Guidelines recommend that men aged 50 years or older with a diagnosis of hypogonadism undergo bone mineral density (BMD) testing.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>The objective of this study was to determine the frequency at which men aged 50 years or older with a diagnosis of hypogonadism undergo BMD testing, and if found to have low BMD, are subsequently treated with an osteoporosis medication.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A retrospective chart review was conducted at a large academic medical center. Inclusion requirements were an International Classification of Diseases (ICD)-9 or -10 code for hypogonadism at any time between July 1, 2012 and September 30, 2020. Patients were followed until the date of BMD assessment or censoring (September 30, 2021). BMD results and treatment with osteoporosis medication were recorded.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 10\u2005169 men with hypogonadism were identified, of whom the mean age was 63.4 (\u00b1\u20059.2), 86.3% White, mean body mass index 31.3 with prevalence of chronic kidney disease, type 2 diabetes, and hypertension of 20.6%, 36.9%, and 68.2%, respectively. The percentage that underwent BMD testing was 7.2%, of which 352 (48.4%) and 87 (12.0%) had osteopenia and osteoporosis, respectively. Among the 87 patients with osteoporosis, 57.5% were treated with an osteoporosis medication.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Only 7.2% of hypogonadal men underwent BMD testing, and among them, 12.0% were found to have osteoporosis. Among those with osteoporosis, 57.5% underwent treatment with osteoporosis medication. Further studies are needed to determine why so few men with hypogonadism undergo BMD assessment and what systems can be put in place to overcome this clinical conundrum.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1210\/jendso\/bvac129","type":"journal-article","created":{"date-parts":[[2022,8,16]],"date-time":"2022-08-16T17:57:38Z","timestamp":1660672658000},"source":"Crossref","is-referenced-by-count":5,"title":["Lack of Bone Mineral Density Testing in Men With Hypogonadism: A Clinical Conundrum"],"prefix":"10.1210","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0886-5554","authenticated-orcid":false,"given":"Travis","family":"Goettemoeller","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Cleveland Clinic , Cleveland, Ohio 44195 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Bena","sequence":"additional","affiliation":[{"name":"Section of Biostatistics, Quantitative Health Sciences, Cleveland Clinic , Cleveland, Ohio 44195 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin M","family":"Pantalone","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Diabetes and Metabolism, Cleveland Clinic , Cleveland, Ohio 44195 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","published-online":{"date-parts":[[2022,8,16]]},"reference":[{"issue":"4","key":"2022091316572217700_CIT0001","doi-asserted-by":"crossref","first-page":"2105","DOI":"10.3390\/ijms22042105","article-title":"Osteoporosis in men: a review of an underestimated bone condition","volume":"22","author":"Rinonapoli","year":"2021","journal-title":"Int J Mol Sci"},{"issue":"4","key":"2022091316572217700_CIT0002","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1177\/1557988313478826","article-title":"Screening for osteoporosis in men aged 70 years and older in a primary care setting in the United States","volume":"7","author":"Lim","year":"2013","journal-title":"Am J Mens Health."},{"issue":"4","key":"2022091316572217700_CIT0003","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/j.jocd.2014.01.009","article-title":"Screening and treatment of osteoporosis after hip fracture: comparison of sex and race","volume":"17","author":"Antonelli","year":"2014","journal-title":"J Clin Densitom."},{"issue":"19","key":"2022091316572217700_CIT0004","doi-asserted-by":"crossref","first-page":"2217","DOI":"10.1001\/archinte.162.19.2217","article-title":"Undertreatment of osteoporosis in men with hip fracture","volume":"162","author":"Kiebzak","year":"2002","journal-title":"Arch Intern Med."},{"key":"2022091316572217700_CIT0005","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1007\/s11657-012-0113-0","article-title":"Gender differences in osteoporosis screening: retrospective analysis","volume":"7","author":"Alswat","year":"2012","journal-title":"Arch Osteoporos."},{"issue":"8","key":"2022091316572217700_CIT0006","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1007\/s00198-005-1950-0","article-title":"The near absence of osteoporosis treatment in older men with fractures","volume":"16","author":"Feldstein","year":"2005","journal-title":"Osteoporos Int."},{"issue":"21","key":"2022091316572217700_CIT0007","doi-asserted-by":"crossref","first-page":"1820","DOI":"10.2106\/JBJS.M.01497","article-title":"Distal radial fractures in older men. A missed opportunity?","volume":"96","author":"Harper","year":"2014","journal-title":"J Bone Joint Surg Am."},{"issue":"1","key":"2022091316572217700_CIT0008","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1001\/archinternmed.2007.2","article-title":"Endogenous sex hormones and incident fracture risk in older men: the Dubbo Osteoporosis Epidemiology Study","volume":"168","author":"Meier","year":"2008","journal-title":"Arch Intern Med."},{"issue":"10","key":"2022091316572217700_CIT0009","doi-asserted-by":"crossref","first-page":"3908","DOI":"10.1210\/jc.2006-0173","article-title":"Association of testosterone and estradiol deficiency with osteoporosis and rapid bone loss in older men","volume":"91","author":"Fink","year":"2006","journal-title":"J Clin Endocrinol Metab."},{"issue":"1","key":"2022091316572217700_CIT0010","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1097\/00000441-199207000-00003","article-title":"Testosterone deficiency as a risk factor for hip fractures in men: a case-control study","volume":"304","author":"Jackson","year":"1992","journal-title":"Am J Med Sci."},{"key":"2022091316572217700_CIT0011","doi-asserted-by":"crossref","first-page":"4602129","DOI":"10.1155\/2017\/4602129","article-title":"Male hypogonadism and osteoporosis: the effects, clinical consequences, and treatment of testosterone deficiency in bone health","volume":"2017","author":"Golds","year":"2017","journal-title":"Int J Endocrinol."},{"issue":"6","key":"2022091316572217700_CIT0012","doi-asserted-by":"crossref","first-page":"1802","DOI":"10.1210\/jc.2011-3045","article-title":"Osteoporosis in men: an Endocrine Society clinical practice guideline","volume":"97","author":"Watts","year":"2012","journal-title":"J Clin Endocrinol Metab."},{"issue":"10","key":"2022091316572217700_CIT0013","doi-asserted-by":"crossref","first-page":"2359","DOI":"10.1007\/s00198-014-2794-2","article-title":"Clinician\u2019s guide to prevention and treatment of osteoporosis [published correction appears in Osteoporos Int. 2015;26(7):2045-2047]","volume":"25","author":"Cosman","year":"2014","journal-title":"Osteoporos Int."},{"key":"2022091316572217700_CIT0014","author":"The International Society for Clinical Densitometry."},{"key":"2022091316572217700_CIT0015","author":"United States Preventive Services Taskforce.","year":"2018"},{"key":"2022091316572217700_CIT0016","author":"US Centers for Medicare and Medicaid Services."},{"issue":"405","key":"2022091316572217700_CIT0017","first-page":"1","article-title":"Osteoporosis or low bone mass in older adults: United States, 2017-2018","author":"Sarafrazi","year":"2021","journal-title":"NCHS Data Brief."}],"container-title":["Journal of the Endocrine Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jes\/advance-article-pdf\/doi\/10.1210\/jendso\/bvac129\/45448133\/bvac129.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jes\/article-pdf\/6\/10\/bvac129\/45813415\/bvac129.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jes\/article-pdf\/6\/10\/bvac129\/45813415\/bvac129.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,13]],"date-time":"2022-09-13T16:57:51Z","timestamp":1663088271000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jes\/article\/doi\/10.1210\/jendso\/bvac129\/6668728"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,16]]},"references-count":17,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2022,10,1]]}},"URL":"https:\/\/doi.org\/10.1210\/jendso\/bvac129","relation":{},"ISSN":["2472-1972"],"issn-type":[{"value":"2472-1972","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2022,10,1]]},"published":{"date-parts":[[2022,8,16]]},"article-number":"bvac129"}}