{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T07:26:34Z","timestamp":1769239594145,"version":"3.49.0"},"reference-count":30,"publisher":"The Endocrine Society","issue":"1","license":[{"start":{"date-parts":[[2022,11,8]],"date-time":"2022-11-08T00:00:00Z","timestamp":1667865600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"Hypera Pharma"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,11,17]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Context<\/jats:title>\n                  <jats:p>There are few studies of 25-hydroxyvitamin D (25(OH)D) concentrations in healthy adults in Brazil.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>This work aimed to estimate the prevalence of vitamin D status and its association with lifestyle, sociodemographic, and anthropometric data in 3 regions of Brazil.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A cross-sectional study was conducted among blood donors of both sexes, living in the cities of Salvador, S\u00e3o Paulo, and Curitiba during summer. Blood samples were collected during the procedure. Serum 25(OH)D and parathyroid hormone (PTH) were measured in the same laboratory using chemiluminescence immunoassays. Lifestyle, sociodemographic, and anthropometric data were gathered by an interview with a standardized questionnaire. Vitamin D deficiency and insufficiency was defined as 25(OH)D levels below 20\u2005ng\/mL and below 30\u2005ng\/mL, respectively.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 1004 healthy adults were evaluated with mean levels of 25(OH)D (28.7 \u00b1 9.27\u2005ng\/mL) and PTH (34.4 \u00b1 15.1\u2005pg\/mL). The standardized prevalence of vitamin D deficiency and insufficiency was in the study population 15.3% and 50.9%: in Salvador 12.1% and 47.6%, in S\u00e3o Paulo 20.5%, and 52.4% and in Curitiba 12.7% and 52.1%, (P = .0004). PTH levels were negatively correlated with 25(OH)D levels. Greater body mass index (BMI) and higher latitude were significant predictors of vitamin D deficiency, whereas skin color (White), longer duration of sun exposure, and current use of dietary supplement were protective.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>This study confirmed the high prevalence of vitamin D deficiency and insufficiency even in the midsummer in a healthy population of Brazil. Vitamin D levels are associated with sun exposure, latitude, BMI, skin color, and use of supplements.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1210\/jendso\/bvac171","type":"journal-article","created":{"date-parts":[[2022,11,8]],"date-time":"2022-11-08T20:38:27Z","timestamp":1667939907000},"source":"Crossref","is-referenced-by-count":10,"title":["Epidemiology of Vitamin D (EpiVida)\u2014A Study of Vitamin D Status Among Healthy Adults in Brazil"],"prefix":"10.1210","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0555-0880","authenticated-orcid":false,"given":"Victoria Zeghbi Cochenski","family":"Borba","sequence":"first","affiliation":[{"name":"Department of Medicine, Division of Endocrinology, Universidade Federal do Paran\u00e1 , Curitiba, Paran\u00e1 80030110 , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marise","family":"Lazaretti-Castro","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Escola Paulista de Medicina, Universidade Federal de S\u00e3o Paulo , S\u00e3o Paulo 04021-001 , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra da Silva","family":"Moreira","sequence":"additional","affiliation":[{"name":"Gon\u00e7alo Moniz Research Center, Oswaldo Cruz Foundation, Brazilian Ministry of Health , Salvador 40296-710 , Brazil"},{"name":"Clinical Research Center, Charitable Works Foundation of Sister Dulce , Salvador 40415000 , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Concei\u00e7\u00e3o Chagas","family":"de Almeida","sequence":"additional","affiliation":[{"name":"Gon\u00e7alo Moniz Research Center, Oswaldo Cruz Foundation, Brazilian Ministry of Health , Salvador 40296-710 , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr","given":"Edson Duarte","family":"Moreira","sequence":"additional","affiliation":[{"name":"Gon\u00e7alo Moniz Research Center, Oswaldo Cruz Foundation, Brazilian Ministry of Health , Salvador 40296-710 , Brazil"},{"name":"Clinical Research Center, Charitable Works Foundation of Sister Dulce , Salvador 40415000 , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"80","published-online":{"date-parts":[[2022,11,9]]},"reference":[{"issue":"4","key":"2023042622362019400_bvac171-B1","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1210\/er.2018-00126","article-title":"Skeletal and extraskeletal actions of vitamin D: current evidence and outstanding questions","volume":"40","author":"Bouillon","year":"2019","journal-title":"Endocr Rev"},{"issue":"5","key":"2023042622362019400_bvac171-B2","doi-asserted-by":"crossref","first-page":"546","DOI":"10.3390\/nu10050546","article-title":"Italian Association of Clinical Endocrinologists (AME) and Italian Chapter of the American Association of Clinical Endocrinologists (AACE) position statement: clinical management of vitamin D deficiency in 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