{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T17:57:10Z","timestamp":1792173430332,"version":"4.4.0"},"reference-count":24,"publisher":"The Endocrine Society","issue":"10","license":[{"start":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T00:00:00Z","timestamp":1726012800000},"content-version":"vor","delay-in-days":15,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Cross-border Healthcare Intervention Trials Ireland Network"},{"name":"Northern Ireland Public Health Agency"},{"name":"Republic of Ireland Health Research Board"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,8,27]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>This study examined the influence of a pregnancy and postnatal multicomponent lifestyle intervention for women with gestational diabetes mellitus (GDM) and overweight\/obesity from 6 weeks to 12 months postnatal. The primary outcome was weight at 12 months. Secondary outcomes included change in body mass index (BMI), waist circumference (WC) and fasting plasma glucose (FPG).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>The study involved 235 pregnant women with GDM and BMI \u2265\u202f25\u2005kg\/m2 during pregnancy. Intervention components included an educational session, activity tracker (Fitbit), monthly phone calls, weekly motivational text messages, 12-week voucher for a commercial weight management organization and anthropometric, biochemical, and clinical measurements taken at 6 weeks, 6 months, and 12 months postnatal. The control group received routine local maternity care.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A mean weight change of \u22122.0 (SD 7.1) kg was observed in the intervention group compared with \u22120.6 (SD 8.0) kg in the control group, difference \u22121.4 (95% CI \u22124.4, 1.5) kg from 6 weeks to 12 months postnatal, but this was not statistically significant (P = .34). Neither were significant differences obtained for any secondary outcomes: BMI \u22120.6 (\u22121.6, 0.5) kg\/m2, WC \u22121.0 (\u22125.1, 3.2) cm and FPG 0.07 (\u22120.15, 0.29) mmol\/L.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>This lifestyle intervention among women with overweight\/obesity and GDM resulted in a statistically nonsignificant 1.4\u2005kg greater weight loss compared with routine care at 12 months postnatal. Further research is needed to understand how the different components of this lifestyle intervention might be better applied to elicit more successful results.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1210\/jendso\/bvae151","type":"journal-article","created":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T07:26:47Z","timestamp":1726039607000},"source":"Crossref","is-referenced-by-count":3,"title":["A Pregnancy and Postnatal RCT Among Women With Gestational Diabetes Mellitus and Overweight\/Obesity: The PAIGE2 Study"],"prefix":"10.1210","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2919-6321","authenticated-orcid":false,"given":"Bridie J","family":"Kemp","sequence":"first","affiliation":[{"name":"Regional Centre for Endocrinology and Diabetes, Royal Jubilee Maternity Centre, Belfast Health and Social Care Trust , Belfast BT12 6BA 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