{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T06:33:17Z","timestamp":1778740397943,"version":"3.51.4"},"reference-count":44,"publisher":"The Endocrine Society","issue":"12","license":[{"start":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T00:00:00Z","timestamp":1761091200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"NAKO"},{"name":"NAKO"},{"DOI":"10.13039\/501100002347","name":"Federal Ministry of Education and Research","doi-asserted-by":"publisher","award":["01ER1301A\/B\/C"],"award-info":[{"award-number":["01ER1301A\/B\/C"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"Federal Ministry of Education and Research","doi-asserted-by":"publisher","award":["01ER1511D"],"award-info":[{"award-number":["01ER1511D"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"Federal Ministry of Education and Research","doi-asserted-by":"publisher","award":["01ER1801A\/B\/C\/D"],"award-info":[{"award-number":["01ER1801A\/B\/C\/D"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"Federal Ministry of Education and Research","doi-asserted-by":"publisher","award":["01ER2301A\/B\/C"],"award-info":[{"award-number":["01ER2301A\/B\/C"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009318","name":"Helmholtz Association","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009318","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001664","name":"Leibniz Association","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001664","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,11,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Context<\/jats:title>\n                    <jats:p>Neck circumference (NC) was proposed as promising marker to assess body fat distribution and cardiometabolic risk.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>We aimed to assess associations of NC with anthropometric traits, cardiometabolic risk markers, and self-reported cardiometabolic diseases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>NC was measured in a subsample (5865 participants) of the German National Cohort (NAKO Gesundheitsstudie, NAKO), study region Kiel. Linear and logistic regression models were applied to assess associations of NC with anthropometric and cardiometabolic risk markers and self-reported cardiometabolic diseases, including diabetes, heart failure, gout, and a composite end point \u201cclinical CVD\u201d (cardiovascular disease; combining history of angina pectoris, stroke, myocardial infarction, and peripheral artery disease). Models were adjusted for sex and age, CV risk factors (systolic blood pressure, diabetes, low-density lipoprotein [LDL] cholesterol, use of lipid-lowering and antihypertensive medication, smoking status), and body mass index (BMI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Mean NC values (\u00b1SD) were 39.5 \u00b1 3.0 in men and 33.6 \u00b1 2.7\u2005cm in women. NC was positively associated with anthropometric traits, visceral adipose tissue (cm) (\u03b2 = 1.45 [95% CI, 0.88-2.02]), systolic (\u03b2 = .37 [0.19-0.56]) and diastolic (\u03b2 = .17 [0.05-0.29]) blood pressure, glycated hemoglobin A1c (\u03b2 = .02 [0.01-0.02]), nonfasting glucose (\u03b2 = .57 [0.31-0.83]), and inversely associated with high-density lipoprotein cholesterol (\u03b2 = \u2212.73 [\u22120.91; \u22120.54]). Furthermore, NC showed associations with diabetes (odds ratio [OR] = 1.08 [1.02-1.15]), heart failure (OR = 1.12 [1.02-1.23]), and gout (OR = 1.09 [1.01-1.17]). Association with \u201cclinical CVD\u201d did not remain statistically significant after BMI adjustment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>NC was associated with several cardiometabolic risk factors, including glycemic and lipid traits and self-reported cardiometabolic diseases. These observations suggest that NC may be a useful surrogate marker for cardiometabolic risk.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1210\/jendso\/bvaf163","type":"journal-article","created":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T11:29:59Z","timestamp":1761046199000},"source":"Crossref","is-referenced-by-count":1,"title":["Association of Neck Circumference With Cardiometabolic Risk Factors and Diseases in the German National Cohort"],"prefix":"10.1210","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-5239-1346","authenticated-orcid":false,"given":"Eike A","family":"Strathmann","sequence":"first","affiliation":[{"name":"Institute of Epidemiology and Biobank popgen, Christian-Albrechts-University, University Hospital Schleswig-Holstein Campus Kiel , Kiel 24105 ,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilka","family":"Ratjen","sequence":"additional","affiliation":[{"name":"Clinic for Internal Medicine 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D\u00fcsseldorf 40225 ,","place":["Germany"]},{"name":"German Center for Diabetes Research, Partner D\u00fcsseldorf , M\u00fcnchen-Neuherberg 85764 ,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beate","family":"Fischer","sequence":"additional","affiliation":[{"name":"Institute for Epidemiology and Preventive Medicine, University of Regensburg , Regensburg 93053 ,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katharina S","family":"Weber","sequence":"additional","affiliation":[{"name":"Institute of Epidemiology and Biobank popgen, Christian-Albrechts-University, University Hospital Schleswig-Holstein Campus Kiel , Kiel 24105 ,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cara","family":"\u00d6verm\u00f6hle","sequence":"additional","affiliation":[{"name":"Institute of Epidemiology and Biobank popgen, Christian-Albrechts-University, University Hospital Schleswig-Holstein 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