{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T13:51:34Z","timestamp":1770472294548,"version":"3.49.0"},"reference-count":41,"publisher":"The Endocrine Society","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2002,8,1]]},"DOI":"10.1210\/me.2001-0278","type":"journal-article","created":{"date-parts":[[2002,10,1]],"date-time":"2002-10-01T22:03:34Z","timestamp":1033509814000},"page":"1752-1766","source":"Crossref","is-referenced-by-count":107,"title":["Glucocorticoid-Mediated Suppression of Cytokine-Induced Matrix Metalloproteinase-9 Expression in Rat Mesangial Cells: Involvement of Nuclear Factor-\u03baB and Ets Transcription Factors"],"prefix":"10.1210","volume":"16","author":[{"given":"Wolfgang","family":"Eberhardt","sequence":"first","affiliation":[{"name":"Pharmazentrum Frankfurt, Klinikum der Johann Wolfgang Goethe-Universita\u0308t, D-60590 Frankfurt am Main, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maja","family":"Schulze","sequence":"additional","affiliation":[{"name":"Pharmazentrum Frankfurt, Klinikum der Johann Wolfgang Goethe-Universita\u0308t, D-60590 Frankfurt am Main, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina","family":"Engels","sequence":"additional","affiliation":[{"name":"Pharmazentrum Frankfurt, Klinikum der Johann Wolfgang Goethe-Universita\u0308t, D-60590 Frankfurt am Main, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elke","family":"Klasmeier","sequence":"additional","affiliation":[{"name":"Pharmazentrum Frankfurt, Klinikum der Johann Wolfgang Goethe-Universita\u0308t, D-60590 Frankfurt am Main, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josef","family":"Pfeilschifter","sequence":"additional","affiliation":[{"name":"Pharmazentrum Frankfurt, Klinikum der Johann Wolfgang Goethe-Universita\u0308t, D-60590 Frankfurt am Main, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"80","reference":[{"key":"2019041123060282400_R1","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1042\/cs0940557","article-title":"Anti-inflammatory actions of glucocorticoids: molecular mechanisms.","volume":"94","author":"Barnes","year":"1998","journal-title":"Clin Sci"},{"key":"2019041123060282400_R2","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/0039-128X(96)00032-3","article-title":"Interaction of the Ubc9 human homologue with c-Jun and with the glucocorticoid receptor.","volume":"61","author":"Go\u0308ttlicher","year":"1996","journal-title":"Steroids"},{"key":"2019041123060282400_R3","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1126\/science.270.5234.286","article-title":"Immunosuppression by glucocorticoids: inhibition of NF-\u03baB activity through induction of I\u03baB synthesis.","volume":"270","author":"Auphan","year":"1995","journal-title":"Science"},{"key":"2019041123060282400_R4","first-page":"401","article-title":"Negative cross-talk between RelA and the glucocorticoid receptor: a possible mechanism for the antiinflammatory action of glucocorticoids.","volume":"9","author":"Caldenhoven","year":"1995","journal-title":"Mol Endocrinol"},{"key":"2019041123060282400_R5","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1007\/s001090050242","article-title":"Transcriptional cross-talk, the second mode of steroid hormone receptor action.","volume":"76","author":"Go\u0308ttlicher","year":"1998","journal-title":"J Mol Med"},{"key":"2019041123060282400_R6","doi-asserted-by":"crossref","first-page":"21491","DOI":"10.1074\/jbc.274.31.21491","article-title":"Matrix metalloproteinases.","volume":"274","author":"Nagase","year":"1999","journal-title":"J Biol Chem"},{"key":"2019041123060282400_R7","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1038\/ki.1992.103","article-title":"Proteinases and glomerular matrix turnover.","volume":"41","author":"Davies","year":"1992","journal-title":"Kidney Int"},{"key":"2019041123060282400_R8","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1038\/ki.1994.45","article-title":"Role of oxidants and proteases in glomerular injury.","volume":"45","author":"Johnson","year":"1994","journal-title":"Kidney Int"},{"key":"2019041123060282400_R9","first-page":"395","article-title":"Regulatory mechanism of 92 kDa type IV collagenase gene expression which is associated with invasiveness of tumor cells.","volume":"8","author":"Sato","year":"1993","journal-title":"Oncogene"},{"key":"2019041123060282400_R10","doi-asserted-by":"crossref","first-page":"23460","DOI":"10.1016\/S0021-9258(19)49485-4","article-title":"v-Src activates the expression of 92-kDa type IV collagenase gene through the AP-1 site and the GT box homologous to retinoblastoma control elements. A mechanism regulating gene expression independent of that by inflammatory cytokines.","volume":"268","author":"Sato","year":"1993","journal-title":"J Biol Chem"},{"key":"2019041123060282400_R11","first-page":"F123","article-title":"Dual regulation of IL-1\u03b2-mediated matrix metalloproteinase-9 expression in mesangial cells by NF-\u03baB and AP-1.","volume":"270","author":"Yokoo","year":"1996","journal-title":"Am J Physiol"},{"key":"2019041123060282400_R12","doi-asserted-by":"crossref","first-page":"28620","DOI":"10.1016\/S0021-9258(19)61950-2","article-title":"The rabbit gene for 92-kDa matrix metalloproteinase. Role of AP1 and AP2 in cell type-specific transcription.","volume":"269","author":"Fini","year":"1994","journal-title":"J Biol Chem"},{"key":"2019041123060282400_R13","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1046\/j.1523-1755.2000.00808.x","article-title":"Nitric oxide modulates expression of matrix metalloproteinase-9 in rat mesangial cells.","volume":"57","author":"Eberhardt","year":"2000","journal-title":"Kidney Int"},{"key":"2019041123060282400_R14","doi-asserted-by":"crossref","first-page":"5788","DOI":"10.4049\/jimmunol.165.10.5788","article-title":"Amplification of IL-1\u03b2-induced matrix metalloproteinase-9 expression by superoxide in rat glomerular mesangial cells is mediated by increased activities of NF-\u03baB and activating protein-1 and involves activation of the mitogen-activated protein kinase pathways.","volume":"165","author":"Eberhardt","year":"2000","journal-title":"J Immunol"},{"key":"2019041123060282400_R15","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1111\/j.1432-1033.1993.tb19864.x","article-title":"The Ets family of transcription factors.","volume":"211","author":"Wasylyk","year":"1993","journal-title":"Eur J Biochem"},{"key":"2019041123060282400_R16","doi-asserted-by":"crossref","first-page":"4631","DOI":"10.1002\/j.1460-2075.1992.tb05565.x","article-title":"Spatial flexibility in ternary complexes between SRF and its accessory proteins.","volume":"11","author":"Treisman","year":"1992","journal-title":"EMBO J"},{"key":"2019041123060282400_R17","doi-asserted-by":"crossref","first-page":"23907","DOI":"10.1074\/jbc.271.39.23907","article-title":"Androgen receptor-Ets protein interaction is a novel mechanism for steroid hormone-mediated down-modulation of matrix metalloproteinase expression.","volume":"271","author":"Schneikert","year":"1996","journal-title":"J Biol Chem"},{"key":"2019041123060282400_R18","first-page":"1461","article-title":"Ets-related protein E1A-F can activate three different matrix metalloproteinase gene promoters.","volume":"10","author":"Higashino","year":"1995","journal-title":"Oncogene"},{"key":"2019041123060282400_R19","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1002\/(SICI)1097-0215(19980703)77:1<128::AID-IJC20>3.0.CO;2-9","article-title":"The Ets-1 and Ets-2 transcription factors activate the promoters for invasion-associated drokinase and collagenase genes in response to epidermal growth factor.","volume":"77","author":"Watabe","year":"1998","journal-title":"Int J Cancer"},{"key":"2019041123060282400_R20","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1165\/ajrcmb.20.5.3260","article-title":"Overexpression of alveolar macrophage gelatinase B (MMP-9) in patients with idiopathic pulmonary fibrosis: effects of steroid and immunosuppressive treatment.","volume":"20","author":"Lemjabber","year":"1999","journal-title":"Am J Respir Cell Mol Biol"},{"key":"2019041123060282400_R21","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1006\/excr.1998.4049","article-title":"Matrix metalloproteinases (MMPs) and their physiological inhibitors (TIMPs) are differentially expressed during skin wound repair.","volume":"242","author":"Madlemer","year":"1998","journal-title":"Exp Cell Res"},{"key":"2019041123060282400_R22","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1006\/cbir.1996.0008","article-title":"Therapeutic strategies for the inhibition id inducible nitric oxide synthase: potential for a novel class of anti-inflammatry agents.","volume":"20","author":"Pfeilcschifter","year":"1996","journal-title":"Cell Biol Int"},{"key":"2019041123060282400_R23","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1093\/brain\/123.4.698","article-title":"Dexamethasone regulation of matrix metalloproteinase expression in CNS vascular endothelium.","volume":"123","author":"Harkness","year":"2000","journal-title":"Brain"},{"key":"2019041123060282400_R24","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1177\/00220345960750030901","article-title":"Effects of dexamethasone and cell proliferation on the expression of matrix metalloproteinases in human mucosal normal and malignant cells.","volume":"75","author":"Kylmaniemi","year":"1996","journal-title":"J Dent Res"},{"key":"2019041123060282400_R25","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1164\/ajrccm.160.1.9808087","article-title":"Tissue inhibitor of metalloproteinase-1 levels in bronchoalveolar lavage fluid from asthmatic subjects.","volume":"160","author":"Mautino","year":"1999","journal-title":"Am J Respir Crit Care Med"},{"key":"2019041123060282400_R26","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1038\/sj.onc.1201587","article-title":"Ursolic acid-induced down-regulation of MMP-9 gene is mediated through the nuclear translocation of glucocorticoid receptor in HT1080 human fibrosarcoma cells.","volume":"16","author":"Cha","year":"1998","journal-title":"Oncogene"},{"key":"2019041123060282400_R27","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1111\/1523-1747.ep12363823","article-title":"Demonstration of 72-kDa and 92-kDa forms of type IV collagenase in human skin: variable expression in various blistering diseases, induction during re-epithelialization, and decrease by topical glucocorticoids.","volume":"101","author":"Oikarinen","year":"1993","journal-title":"J Invest Dermatol"},{"key":"2019041123060282400_R28","doi-asserted-by":"crossref","first-page":"2465","DOI":"10.1038\/sj.onc.1204388","article-title":"Cross-talk between glucocorticoid receptor and AP-1.","volume":"20","author":"Herrlich","year":"2001","journal-title":"Oncogene"},{"key":"2019041123060282400_R29","doi-asserted-by":"crossref","first-page":"24383","DOI":"10.1074\/jbc.M909396199","article-title":"Tumor necrosis factor-\u03b1 activation of NF-\u03baB requires the phosphorylation of Ser-471 in the transactivation domain of c-Rel.","volume":"275","author":"Martin","year":"2000","journal-title":"J Biol Chem"},{"key":"2019041123060282400_R30","doi-asserted-by":"crossref","first-page":"1912","DOI":"10.1126\/science.8096091","article-title":"NF-\u03baB controls expression of inhibitor I\u03baB\u03b1: evidence for an inducible autoregulatory pathway.","volume":"259","author":"Sun","year":"1993","journal-title":"Science"},{"key":"2019041123060282400_R31","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1073\/pnas.93.1.255","article-title":"Molecular mechanisms of dexamethasone inhibition of nitric oxide synthase expression in interleukin 1\u03b2-stimulated mesangial cells: evidence for the involvement of transcriptional and posttranscriptional regulation.","volume":"93","author":"Kunz","year":"1996","journal-title":"Proc Natl Acad Sci USA"},{"key":"2019041123060282400_R32","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.1002\/j.1460-2075.1990.tb07394.x","article-title":"The collagenase gene promoter contains a TPA and oncogene-responsive unit encompassing the PEA3 and AP-1 binding sites.","volume":"9","author":"Gutman","year":"1990","journal-title":"EMBO J"},{"key":"2019041123060282400_R33","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1002\/j.1460-2075.1991.tb08053.x","article-title":"The c-Ets oncoprotein activates the stromelysin promoter through the same elements as several non-nuclear oncoproteins.","volume":"10","author":"Wasylyk","year":"1991","journal-title":"EMBO J"},{"key":"2019041123060282400_R34","doi-asserted-by":"crossref","first-page":"10672","DOI":"10.1074\/jbc.271.18.10672","article-title":"Stimulation of 92-kDa gelatinase B promoter activity by ras is mitogen-activated protein kinase kinase 1-independent and requires multiple transcription factor binding sites including closely spaced PEA3\/ets and AP-1 sequences.","volume":"271","author":"Gum","year":"1996","journal-title":"J Biol Chem"},{"key":"2019041123060282400_R35","doi-asserted-by":"crossref","first-page":"4573","DOI":"10.1002\/j.1460-2075.1992.tb05559.x","article-title":"A regulatory element that mediates co-operation between a PEA3-AP-1 element and an AP-1 site is required for phorbol ester induction of urokinase enhancer activity in HepG2 hepatoma cells.","volume":"11","author":"Nerlov","year":"1992","journal-title":"EMBO J"},{"key":"2019041123060282400_R36","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1074\/jbc.271.2.774","article-title":"Synergistic transcriptional activation of the tissue inhibitor of metalloproteinases-1 promoter via functional interaction of AP-1 and Ets-1 transcription factors.","volume":"271","author":"Logan","year":"1996","journal-title":"J Biol Chem"},{"key":"2019041123060282400_R37","doi-asserted-by":"crossref","first-page":"18007","DOI":"10.1074\/jbc.M100671200","article-title":"Physical interaction and functional synergy between glucocorticoid receptor and Ets2 proteins for transcription activation of the cytochrome P-450c27 promoter.","volume":"276","author":"Mullick","year":"2001","journal-title":"J Biol Chem"},{"key":"2019041123060282400_R38","doi-asserted-by":"crossref","first-page":"4116","DOI":"10.1128\/MCB.14.6.4116","article-title":"Participation of Ets transcription factors in the glucocorticoid response of the rat tyrosine aminotransferase gene.","volume":"14","author":"Espinas","year":"1994","journal-title":"Mol Cell Biol"},{"key":"2019041123060282400_R39","doi-asserted-by":"crossref","first-page":"4961","DOI":"10.4049\/jimmunol.160.10.4961","article-title":"Molecular mechanisms of inducible nitric oxide synthase gene expression by IL-1\u03b2 and cAMP in rat mesangial cells.","volume":"160","author":"Eberhardt","year":"1998","journal-title":"J Immunol"},{"key":"2019041123060282400_R40","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S0014-5793(98)01035-7","article-title":"Potentiation of nitric oxide synthase expression by superoxide in interleukin 1\u03b2-stimulated rat mesangial cells.","volume":"435","author":"Beck","year":"1998","journal-title":"FEBS Lett"},{"key":"2019041123060282400_R41","first-page":"626","article-title":"Regulation of interleukin-18 (IL-18) expression in keratinocytes (HaCaT): implications for early wound healing.","volume":"11","author":"Ka\u0308mpfer","year":"2000","journal-title":"Eur Cytokine Netw"}],"container-title":["Molecular Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/mend\/article-pdf\/16\/8\/1752\/8962964\/mend1752.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,24]],"date-time":"2023-04-24T19:39:23Z","timestamp":1682365163000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/mend\/article\/16\/8\/1752\/2741571"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,8,1]]},"references-count":41,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2002,8,1]]}},"URL":"https:\/\/doi.org\/10.1210\/me.2001-0278","relation":{},"ISSN":["0888-8809","1944-9917"],"issn-type":[{"value":"0888-8809","type":"print"},{"value":"1944-9917","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,8,1]]}}}