{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T06:26:53Z","timestamp":1790749613076,"version":"4.1.0"},"reference-count":34,"publisher":"The Endocrine Society","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,9,1]]},"DOI":"10.1210\/me.2015-1089","type":"journal-article","created":{"date-parts":[[2015,8,10]],"date-time":"2015-08-10T17:00:27Z","timestamp":1439226027000},"page":"1334-1346","source":"Crossref","is-referenced-by-count":20,"title":["Androgen Receptor Coactivator ARID4B Is Required for the Function of Sertoli Cells in Spermatogenesis"],"prefix":"10.1210","volume":"29","author":[{"given":"Ray-Chang","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Biochemistry and Molecular Medicine (R.-C.W., Y.Z., M.-Y.W.), The George Washington University, Washington, DC 20037"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Zeng","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Medicine (R.-C.W., Y.Z., M.-Y.W.), The George Washington University, Washington, DC 20037"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I-Wen","family":"Pan","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery (I-W.P.), Texas Children's Hospital and Baylor College of Medicine, Houston, Texas 77030"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei-Yi","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Medicine (R.-C.W., Y.Z., M.-Y.W.), The George Washington University, Washington, DC 20037"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"80","reference":[{"key":"2019041122082329900_B1","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1210\/er.2003-0022","article-title":"Sertoli-Sertoli and Sertoli-germ cell interactions and their significance in germ cell movement in the seminiferous epithelium during spermatogenesis","volume":"25","author":"Mruk","year":"2004","journal-title":"Endocr Rev"},{"key":"2019041122082329900_B2","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1530\/rep.0.1250769","article-title":"Proliferation and functional maturation of Sertoli cells, and their relevance to disorders of testis function in adulthood","volume":"125","author":"Sharpe","year":"2003","journal-title":"Reproduction"},{"key":"2019041122082329900_B3","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1095\/biolreprod.111.095091","article-title":"Is the adult Sertoli cell terminally differentiated?","volume":"87","author":"Tarulli","year":"2012","journal-title":"Biol Reprod"},{"key":"2019041122082329900_B4","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.ygeno.2005.03.013","article-title":"Nomenclature of the ARID family of DNA-binding proteins","volume":"86","author":"Wilsker","year":"2005","journal-title":"Genomics"},{"key":"2019041122082329900_B5","doi-asserted-by":"crossref","first-page":"6632","DOI":"10.1128\/MCB.19.10.6632","article-title":"RBP1 recruits both histone deacetylase-dependent and -independent repression activities to retinoblastoma family proteins","volume":"19","author":"Lai","year":"1999","journal-title":"Mol Cell Biol"},{"key":"2019041122082329900_B6","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/j.tibs.2013.08.002","article-title":"Tudor: a versatile family of histone methylation 'readers'","volume":"38","author":"Lu","year":"2013","journal-title":"Trends Biochem Sci"},{"key":"2019041122082329900_B7","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1093\/jb\/mvu032","article-title":"Biochemical and structural properties of heterochromatin protein 1: understanding its role in chromatin assembly","volume":"156","author":"Nishibuchi","year":"2014","journal-title":"J Biochem"},{"key":"2019041122082329900_B8","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1038\/352251a0","article-title":"Cloning of cDNAs for cellular proteins that bind to the retinoblastoma gene product","volume":"352","author":"Defeo-Jones","year":"1991","journal-title":"Nature"},{"key":"2019041122082329900_B9","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1093\/jnci\/93.15.1159","article-title":"RBP1L1, a retinoblastoma-binding protein-related gene encoding an antigenic epitope abundantly expressed in human carcinomas and normal testis","volume":"93","author":"Cao","year":"2001","journal-title":"J Natl Cancer Inst"},{"key":"2019041122082329900_B10","doi-asserted-by":"crossref","first-page":"2859","DOI":"10.1101\/gad.1452206","article-title":"Deficiency of Rbbp1\/Arid4a and Rbbp1l1\/Arid4b alters epigenetic modifications and suppresses an imprinting defect in the PWS\/AS domain","volume":"20","author":"Wu","year":"2006","journal-title":"Genes Dev"},{"key":"2019041122082329900_B11","doi-asserted-by":"crossref","first-page":"3456","DOI":"10.1128\/MCB.23.10.3456-3467.2003","article-title":"Identification and characterization of three new components of the mSin3A corepressor complex","volume":"23","author":"Fleischer","year":"2003","journal-title":"Mol Cell Biol"},{"key":"2019041122082329900_B12","doi-asserted-by":"crossref","first-page":"2918","DOI":"10.1128\/MCB.21.8.2918-2932.2001","article-title":"RBP1 recruits the mSIN3-histone deacetylase complex to the pocket of retinoblastoma tumor suppressor family proteins found in limited discrete regions of the nucleus at growth arrest","volume":"21","author":"Lai","year":"2001","journal-title":"Mol Cell Biol"},{"key":"2019041122082329900_B13","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1093\/jnci\/djn253","article-title":"Identification of chromatin remodeling genes Arid4a and Arid4b as leukemia suppressor genes","volume":"100","author":"Wu","year":"2008","journal-title":"J Natl Cancer Inst"},{"key":"2019041122082329900_B14","doi-asserted-by":"crossref","first-page":"4616","DOI":"10.1073\/pnas.1218318110","article-title":"ARID4A and ARID4B regulate male fertility, a functional link to the AR and RB pathways","volume":"110","author":"Wu","year":"2013","journal-title":"Proc Natl Acad Sci USA"},{"key":"2019041122082329900_B15","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1242\/dev.00957","article-title":"Androgen receptor function is required in Sertoli cells for the terminal differentiation of haploid spermatids","volume":"131","author":"Holdcraft","year":"2004","journal-title":"Development"},{"key":"2019041122082329900_B16","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1002\/stem.464","article-title":"Sin3a is required by Sertoli cells to establish a niche for undifferentiated spermatogonia, germ cell tumors, and spermatid elongation","volume":"28","author":"Payne","year":"2010","journal-title":"Stem Cells"},{"key":"2019041122082329900_B17","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.cell.2004.12.022","article-title":"Rhox: a new homeobox gene cluster","volume":"120","author":"Maclean","year":"2005","journal-title":"Cell"},{"key":"2019041122082329900_B18","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1095\/biolreprod.108.068627","article-title":"Seminiferous tubule degeneration and infertility in mice with sustained activation of WNT\/CTNNB1 signaling in Sertoli cells","volume":"79","author":"Boyer","year":"2008","journal-title":"Biol Reprod"},{"key":"2019041122082329900_B19","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1095\/biolreprod.109.079335","article-title":"Constitutive WNT\/\u03b2-catenin signaling in murine Sertoli cells disrupts their differentiation and ability to support spermatogenesis","volume":"82","author":"Tanwar","year":"2010","journal-title":"Biol Reprod"},{"key":"2019041122082329900_B20","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.ydbio.2005.08.039","article-title":"Sertoli cell differentiation is induced both cell-autonomously and through prostaglandin signaling during mammalian sex determination","volume":"287","author":"Wilhelm","year":"2005","journal-title":"Dev Biol"},{"key":"2019041122082329900_B21","doi-asserted-by":"crossref","first-page":"16696","DOI":"10.1073\/pnas.0506084102","article-title":"Androgens regulate the permeability of the blood-testis barrier","volume":"102","author":"Meng","year":"2005","journal-title":"Proc Natl Acad Sci USA"},{"key":"2019041122082329900_B22","doi-asserted-by":"crossref","first-page":"e14168","DOI":"10.1371\/journal.pone.0014168","article-title":"Selective ablation of the androgen receptor in mouse Sertoli cells affects Sertoli cell maturation, barrier formation and cytoskeletal development","volume":"5","author":"Willems","year":"2010","journal-title":"PLoS One"},{"key":"2019041122082329900_B23","doi-asserted-by":"crossref","first-page":"2674","DOI":"10.1210\/en.2004-1630","article-title":"The role of androgens in Sertoli cell proliferation and functional maturation: studies in mice with total or Sertoli cell-selective ablation of the androgen receptor","volume":"146","author":"Tan","year":"2005","journal-title":"Endocrinology"},{"key":"2019041122082329900_B24","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.1210\/mend.15.10.0708","article-title":"New androgen response elements in the murine pem promoter mediate selective transactivation","volume":"15","author":"Barbulescu","year":"2001","journal-title":"Mol Endocrinol"},{"key":"2019041122082329900_B25","doi-asserted-by":"crossref","first-page":"6876","DOI":"10.1073\/pnas.0307306101","article-title":"Infertility with defective spermatogenesis and hypotestosteronemia in male mice lacking the androgen receptor in Sertoli cells","volume":"101","author":"Chang","year":"2004","journal-title":"Proc Natl Acad Sci USA"},{"key":"2019041122082329900_B26","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1073\/pnas.0308114100","article-title":"A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis","volume":"101","author":"De Gendt","year":"2004","journal-title":"Proc Natl Acad Sci USA"},{"key":"2019041122082329900_B27","doi-asserted-by":"crossref","first-page":"18975","DOI":"10.1073\/pnas.0608565103","article-title":"Differential effects of spermatogenesis and fertility in mice lacking androgen receptor in individual testis cells","volume":"103","author":"Tsai","year":"2006","journal-title":"Proc Natl Acad Sci USA"},{"key":"2019041122082329900_B28","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1098\/rstb.2009.0117","article-title":"Androgens and spermatogenesis: lessons from transgenic mouse models","volume":"365","author":"Verhoeven","year":"2010","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"2019041122082329900_B29","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1210\/er.2008-0025","article-title":"Androgen receptor roles in spermatogenesis and fertility: lessons from testicular cell-specific androgen receptor knockout mice","volume":"30","author":"Wang","year":"2009","journal-title":"Endocr Rev"},{"key":"2019041122082329900_B30","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0303-7207(01)00562-7","article-title":"Endocrine regulation of testicular function in men: implications for contraceptive development","volume":"182","author":"Amory","year":"2001","journal-title":"Mol Cell Endocrinol"},{"key":"2019041122082329900_B31","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1101\/gad.1286905","article-title":"mSin3A corepressor regulates diverse transcriptional networks governing normal and neoplastic growth and survival","volume":"19","author":"Dannenberg","year":"2005","journal-title":"Genes Dev"},{"key":"2019041122082329900_B32","first-page":"3149","article-title":"Characterization of the retinoblastoma binding proteins RBP1 and RBP2","volume":"8","author":"Fattaey","year":"1993","journal-title":"Oncogene"},{"key":"2019041122082329900_B33","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1006\/bbrc.1998.8974","article-title":"Retinoblastoma, a tumor suppressor, is a coactivator for the androgen receptor in human prostate cancer DU145 cells","volume":"248","author":"Yeh","year":"1998","journal-title":"Biochem Biophys Res Commun"},{"key":"2019041122082329900_B34","doi-asserted-by":"crossref","first-page":"1900","DOI":"10.1210\/me.2009-0184","article-title":"Retinoblastoma protein plays multiple essential roles in the terminal differentiation of Sertoli cells","volume":"23","author":"Nalam","year":"2009","journal-title":"Mol Endocrinol"}],"container-title":["Molecular Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/mend\/article-pdf\/29\/9\/1334\/8924497\/mend1334.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,12]],"date-time":"2019-04-12T14:52:25Z","timestamp":1555080745000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/mend\/article\/29\/9\/1334\/2556782"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9,1]]},"references-count":34,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2015,9,1]]}},"URL":"https:\/\/doi.org\/10.1210\/me.2015-1089","relation":{},"ISSN":["0888-8809","1944-9917"],"issn-type":[{"value":"0888-8809","type":"print"},{"value":"1944-9917","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,9,1]]}}}