{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T10:52:12Z","timestamp":1774263132399,"version":"3.50.1"},"reference-count":18,"publisher":"The Endocrine Society","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,12,1]]},"DOI":"10.1210\/jc.2012-1923","type":"journal-article","created":{"date-parts":[[2012,10,31]],"date-time":"2012-10-31T10:32:51Z","timestamp":1351679571000},"page":"E2297-E2306","source":"Crossref","is-referenced-by-count":53,"title":["Analytical Performance Verification of a Molecular Diagnostic for Cytology-Indeterminate Thyroid Nodules"],"prefix":"10.1210","volume":"97","author":[{"given":"P. Sean","family":"Walsh","sequence":"first","affiliation":[{"name":"Veracyte, Inc. (P.S.W., J.I.W., E.Y.T., J.D.R., D.C.C., D.I.C., M.P., D.G.P., M.W., J.V., L.F., R.M., R.B.L., G.C.K.), South San Francisco, California 94080"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan I.","family":"Wilde","sequence":"additional","affiliation":[{"name":"Veracyte, Inc. (P.S.W., J.I.W., E.Y.T., J.D.R., D.C.C., D.I.C., M.P., D.G.P., M.W., J.V., L.F., R.M., R.B.L., G.C.K.), South San Francisco, California 94080"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward Y.","family":"Tom","sequence":"additional","affiliation":[{"name":"Veracyte, Inc. (P.S.W., J.I.W., E.Y.T., J.D.R., D.C.C., D.I.C., M.P., D.G.P., M.W., J.V., L.F., R.M., R.B.L., G.C.K.), South San Francisco, California 94080"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica D.","family":"Reynolds","sequence":"additional","affiliation":[{"name":"Veracyte, Inc. (P.S.W., J.I.W., E.Y.T., J.D.R., D.C.C., D.I.C., M.P., D.G.P., M.W., J.V., L.F., R.M., R.B.L., G.C.K.), South San Francisco, California 94080"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daphne C.","family":"Chen","sequence":"additional","affiliation":[{"name":"Veracyte, Inc. (P.S.W., J.I.W., E.Y.T., J.D.R., D.C.C., D.I.C., M.P., D.G.P., M.W., J.V., L.F., R.M., R.B.L., G.C.K.), South San Francisco, California 94080"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Darya I.","family":"Chudova","sequence":"additional","affiliation":[{"name":"Veracyte, Inc. (P.S.W., J.I.W., E.Y.T., J.D.R., D.C.C., D.I.C., M.P., D.G.P., M.W., J.V., L.F., R.M., R.B.L., G.C.K.), South San Francisco, California 94080"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moraima","family":"Pagan","sequence":"additional","affiliation":[{"name":"Veracyte, Inc. (P.S.W., J.I.W., E.Y.T., J.D.R., D.C.C., D.I.C., M.P., D.G.P., M.W., J.V., L.F., R.M., R.B.L., G.C.K.), South San Francisco, California 94080"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel G.","family":"Pankratz","sequence":"additional","affiliation":[{"name":"Veracyte, Inc. (P.S.W., J.I.W., E.Y.T., J.D.R., D.C.C., D.I.C., M.P., D.G.P., M.W., J.V., L.F., R.M., R.B.L., G.C.K.), South San Francisco, California 94080"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mei","family":"Wong","sequence":"additional","affiliation":[{"name":"Veracyte, Inc. (P.S.W., J.I.W., E.Y.T., J.D.R., D.C.C., D.I.C., M.P., D.G.P., M.W., J.V., L.F., R.M., R.B.L., G.C.K.), South San Francisco, California 94080"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Veitch","sequence":"additional","affiliation":[{"name":"Veracyte, Inc. (P.S.W., J.I.W., E.Y.T., J.D.R., D.C.C., D.I.C., M.P., D.G.P., M.W., J.V., L.F., R.M., R.B.L., G.C.K.), South San Francisco, California 94080"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lyssa","family":"Friedman","sequence":"additional","affiliation":[{"name":"Veracyte, Inc. (P.S.W., J.I.W., E.Y.T., J.D.R., D.C.C., D.I.C., M.P., D.G.P., M.W., J.V., L.F., R.M., R.B.L., G.C.K.), South San Francisco, California 94080"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Monroe","sequence":"additional","affiliation":[{"name":"Veracyte, Inc. (P.S.W., J.I.W., E.Y.T., J.D.R., D.C.C., D.I.C., M.P., D.G.P., M.W., J.V., L.F., R.M., R.B.L., G.C.K.), South San Francisco, California 94080"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David L.","family":"Steward","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery (D.L.S.), University of Cincinnati College of Medicine, Cincinnati, Ohio 45267"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark A.","family":"Lupo","sequence":"additional","affiliation":[{"name":"the Thyroid and Endocrine Center of Florida (M.A.L.), Sarasota, Florida 34239"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard B.","family":"Lanman","sequence":"additional","affiliation":[{"name":"Veracyte, Inc. (P.S.W., J.I.W., E.Y.T., J.D.R., D.C.C., D.I.C., M.P., D.G.P., M.W., J.V., L.F., R.M., R.B.L., G.C.K.), South San Francisco, California 94080"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giulia C.","family":"Kennedy","sequence":"additional","affiliation":[{"name":"Veracyte, Inc. (P.S.W., J.I.W., E.Y.T., J.D.R., D.C.C., D.I.C., M.P., D.G.P., M.W., J.V., L.F., R.M., R.B.L., G.C.K.), South San Francisco, California 94080"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"80","reference":[{"key":"key\n\t\t\t\t2019041113273843200_B1","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1089\/thy.2009.0110","article-title":"Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer.","volume":"19","author":"Cooper","year":"2009","journal-title":"Thyroid"},{"key":"key\n\t\t\t\t2019041113273843200_B2","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1002\/cncr.22955","article-title":"Fine-needle aspiration of thyroid nodules: a study of 4703 patients with histologic and clinical correlations.","volume":"111","author":"Yang","year":"2007","journal-title":"Cancer"},{"key":"key\n\t\t\t\t2019041113273843200_B3","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1089\/10507250050137806","article-title":"Risk factors for malignancy of thyroid nodules initially identified as follicular neoplasia by fine-needle aspiration: results of a prospective study of one hundred twenty patients.","volume":"10","author":"Raber","year":"2000","journal-title":"Thyroid"},{"key":"key\n\t\t\t\t2019041113273843200_B4","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1007\/BF03346587","article-title":"American Association of Clinical Endocrinologists, Associazione Medici Endocrinologi, and European Thyroid Association medical guidelines for clinical practice for the diagnosis and management of thyroid nodules: Executive Summary of recommendations.","volume":"33","author":"Gharib","year":"2010","journal-title":"J Endocrinol Invest"},{"key":"key\n\t\t\t\t2019041113273843200_B5","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1002\/dc.10043","article-title":"Diagnosis of \u201cfollicular neoplasm\u201d: a gray zone in thyroid fine-needle aspiration cytology.","volume":"26","author":"Baloch","year":"2002","journal-title":"Diagn Cytopathol"},{"key":"key\n\t\t\t\t2019041113273843200_B6","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1002\/dc.20830","article-title":"Diagnostic terminology and morphologic criteria for cytologic diagnosis of thyroid lesions: a synopsis of the National Cancer Institute Thyroid Fine-Needle Aspiration State of the Science Conference.","volume":"36","author":"Baloch","year":"2008","journal-title":"Diagn Cytopathol"},{"key":"key\n\t\t\t\t2019041113273843200_B7","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1089\/thy.2010.0280","article-title":"The basis of preoperative vocal fold paralysis in a series of patients undergoing thyroid surgery: the preponderance of benign thyroid disease.","volume":"21","author":"Wang","year":"2011","journal-title":"Thyroid"},{"key":"key\n\t\t\t\t2019041113273843200_B8","doi-asserted-by":"crossref","first-page":"5296","DOI":"10.1210\/jc.2010-1087","article-title":"Molecular classification of thyroid nodules using high-dimensionality genomic data.","volume":"95","author":"Chudova","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041113273843200_B9","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1056\/NEJMoa1203208","article-title":"Preoperative Diagnosis of Benign Thyroid Nodules with Indeterminate Cytology.","volume":"387","author":"Alexander","year":"2012","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2019041113273843200_B10","doi-asserted-by":"crossref","first-page":"E1719","DOI":"10.1210\/jc.2011-0459","article-title":"Cost-effectiveness of a novel molecular test for cytologically indeterminate thyroid nodules.","volume":"96","author":"Li","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041113273843200_B11","article-title":"The impact of benign gene expression classifier test results on the endocrinologist-patient decision to operate on patients with thyroid nodules with indeterminate FNA cytopathology","author":"Duick","year":"2012","journal-title":"Thyroid"},{"key":"key\n\t\t\t\t2019041113273843200_B12","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1097\/GIM.0b013e318184137c","article-title":"The Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Initiative: methods of the EGAPP Working Group.","volume":"11","author":"Teutsch","year":"2009","journal-title":"Genet Med"},{"key":"key\n\t\t\t\t2019041113273843200_B13","article-title":"Quality regulation and clinical utility of laboratory-developed molecular tests","volume-title":"AHRQ Technology Assesment Program","author":"Sun","year":"2010"},{"key":"key\n\t\t\t\t2019041113273843200_B14","volume-title":"Evaluation of genetic testing","author":"Project","year":"2007"},{"key":"key\n\t\t\t\t2019041113273843200_B15","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1007\/s12022-009-9074-2","article-title":"A comparative study of fine needle aspiration and fine needle non-aspiration biopsy on suspected thyroid nodules.","volume":"20","author":"Romitelli","year":"2009","journal-title":"Endocr Pathol"},{"key":"key\n\t\t\t\t2019041113273843200_B16","doi-asserted-by":"crossref","first-page":"3390","DOI":"10.1210\/jc.2011-1469","article-title":"Impact of mutational testing on the diagnosis and management of patients with cytologically indeterminate thyroid nodules: a prospective analysis of 1056 FNA samples.","volume":"96","author":"Nikiforov","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019041113273843200_B17","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1080\/0031302032000174941","article-title":"Validation of assembled nucleic acid-based tests in diagnostic microbiology laboratories.","volume":"36","author":"Dimech","year":"2004","journal-title":"Pathology"},{"key":"key\n\t\t\t\t2019041113273843200_B18","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1373\/clinchem.2006.076497","article-title":"Analytical validation of the Oncotype DX genomic diagnostic test for recurrence prognosis and therapeutic response prediction in node-negative, estrogen receptor-positive breast cancer.","volume":"53","author":"Cronin","year":"2007","journal-title":"Clin Chem"}],"container-title":["The Journal of Clinical Endocrinology & Metabolism"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jcem\/article-pdf\/97\/12\/E2297\/9044691\/jcem2297.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,5]],"date-time":"2019-07-05T00:05:41Z","timestamp":1562285141000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jcem\/article\/97\/12\/E2297\/2536299"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12,1]]},"references-count":18,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2012,12,1]]}},"URL":"https:\/\/doi.org\/10.1210\/jc.2012-1923","relation":{},"ISSN":["0021-972X","1945-7197"],"issn-type":[{"value":"0021-972X","type":"print"},{"value":"1945-7197","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,12,1]]}}}