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Body-mass index (BMI), although widely used, does not capture visceral or ectopic fat.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate how anthropometric measures\u2014BMI, percent body fat, waist circumference (WC), and waist-to-hip ratio (WHR)\u2014relate to MRI-measured visceral adipose tissue (VAT) and hepatic fat fraction (HFF), overall, and by sex.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Cross-sectional analysis within the Canadian Alliance for Healthy Heart and Minds cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Community-based, pan-Canadian prospective study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients or Other Participants<\/jats:title>\n                    <jats:p>6683 apparently healthy adults (mean age 57 \u00b1 9 years; 3665 females) with baseline anthropometric and MRI measures; analyses adjusted for study center.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Intervention(s)<\/jats:title>\n                    <jats:p>Not applicable.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measure(s)<\/jats:title>\n                    <jats:p>MRI-derived VAT and HFF. Associations were estimated using linear regression and mixed models, stratified by sex, ethnicity, age, and BMI category.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Mean BMI was 26.7\u2005kg\/m2, WC 88.3\u2005cm, VAT 71\u2005mL, and HFF 5.7%. Females had lower VAT and HFF than males. Correlations with VAT ranged from 0.35 to 0.77 and with HFF from 0.26 to 0.47. Each 10 cm higher WC was associated with 21.0\u2005mL higher VAT and 2.1% higher HFF; each 5 kg\/m2 higher BMI predicted 24.7\u2005mL and 2.8% higher values. When modeled jointly, WC remained strongly predictive, while BMI contributed modestly. Associations were smaller in females. VAT and HFF increased across WC tertiles within BMI categories.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>WC is a robust surrogate for visceral and hepatic fat across BMI categories, supporting its use when MRI is not feasible.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1210\/jendso\/bvag197","type":"journal-article","created":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T07:04:26Z","timestamp":1788332666000},"source":"Crossref","is-referenced-by-count":0,"title":["Cross-sectional evaluation of anthropometric measures vs MRI-measured visceral and hepatic fat in a Canadian cohort"],"prefix":"10.1210","volume":"10","author":[{"given":"Baraa K","family":"Al-Khazraji","sequence":"first","affiliation":[{"name":"Department of Kinesiology, Faculty of Science, McMaster University , Hamilton, ON L8S 4K1 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