{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T18:24:04Z","timestamp":1790792644259,"version":"4.1.0"},"reference-count":32,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"20","content-domain":{"domain":["neurology.org"],"crossmark-restriction":true},"short-container-title":["Neurology"],"published-print":{"date-parts":[[2010,11,16]]},"DOI":"10.1212\/wnl.0b013e3181fd62bb","type":"journal-article","created":{"date-parts":[[2010,11,15]],"date-time":"2010-11-15T21:43:12Z","timestamp":1289857392000},"page":"1794-1802","update-policy":"https:\/\/doi.org\/10.1212\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":137,"title":["Pregnancy and fetal outcomes after interferon-\u03b2 exposure in multiple sclerosis"],"prefix":"10.1212","volume":"75","author":[{"given":"M.P.","family":"Amato","sequence":"first","affiliation":[{"name":"From the Department of Neurology (M.P.A., E.P., B.H., V.Z.), University of Florence, Florence; Hospital of Gallarate (A.G.), Gallarate (VA); San Raffaele Institute (V.M., L.M., G.C.), University of Milan, Milan; Department of Neurology (F.P.), University of Catania, Catania; Besta Institute (L.L.M.), Milan; Department of Neurology (G.L.M.), University of Genova, Genova; Department of Neurology (C.S.), ASL3 Genovese, Genova; Department of Neurology (M.R.T.), University of Ferrara, Ferrara; Multiple..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Portaccio","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (M.P.A., E.P., B.H., V.Z.), University of Florence, Florence; Hospital of Gallarate (A.G.), Gallarate (VA); San Raffaele Institute (V.M., L.M., G.C.), University of Milan, Milan; Department of Neurology (F.P.), University of Catania, Catania; Besta Institute (L.L.M.), Milan; Department of Neurology (G.L.M.), University of Genova, Genova; Department of Neurology (C.S.), ASL3 Genovese, Genova; Department of Neurology (M.R.T.), University of Ferrara, Ferrara; Multiple..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Ghezzi","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (M.P.A., E.P., B.H., V.Z.), University of Florence, Florence; Hospital of Gallarate (A.G.), Gallarate (VA); San Raffaele Institute (V.M., L.M., G.C.), University of Milan, Milan; Department of Neurology (F.P.), University of Catania, Catania; Besta Institute (L.L.M.), Milan; Department of Neurology (G.L.M.), University of Genova, Genova; Department of Neurology (C.S.), ASL3 Genovese, Genova; Department of Neurology (M.R.T.), University of Ferrara, Ferrara; Multiple..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Hakiki","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (M.P.A., E.P., B.H., V.Z.), University of Florence, Florence; Hospital of Gallarate (A.G.), Gallarate (VA); San Raffaele Institute (V.M., L.M., G.C.), University of Milan, Milan; Department of Neurology (F.P.), University of Catania, Catania; Besta Institute (L.L.M.), Milan; Department of Neurology (G.L.M.), University of Genova, Genova; Department of Neurology (C.S.), ASL3 Genovese, Genova; Department of Neurology (M.R.T.), University of Ferrara, Ferrara; Multiple..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Zipoli","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (M.P.A., E.P., B.H., V.Z.), University of Florence, Florence; Hospital of Gallarate (A.G.), Gallarate (VA); San Raffaele Institute (V.M., L.M., G.C.), University of Milan, Milan; Department of Neurology (F.P.), University of Catania, Catania; Besta Institute (L.L.M.), Milan; Department of Neurology (G.L.M.), University of Genova, Genova; Department of Neurology (C.S.), ASL3 Genovese, Genova; Department of Neurology (M.R.T.), University of Ferrara, Ferrara; Multiple..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Martinelli","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (M.P.A., E.P., B.H., V.Z.), University of Florence, Florence; Hospital of Gallarate (A.G.), Gallarate (VA); San Raffaele Institute (V.M., L.M., G.C.), University of Milan, Milan; Department of Neurology (F.P.), University of Catania, Catania; Besta Institute (L.L.M.), Milan; Department of Neurology (G.L.M.), University of Genova, Genova; Department of Neurology (C.S.), ASL3 Genovese, Genova; Department of Neurology (M.R.T.), University of Ferrara, Ferrara; Multiple..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Moiola","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (M.P.A., E.P., B.H., V.Z.), University of Florence, Florence; Hospital of Gallarate (A.G.), Gallarate (VA); San Raffaele Institute (V.M., L.M., G.C.), University of Milan, Milan; Department of Neurology (F.P.), University of Catania, Catania; Besta Institute (L.L.M.), Milan; Department of Neurology (G.L.M.), University of Genova, Genova; Department of Neurology (C.S.), ASL3 Genovese, Genova; Department of Neurology (M.R.T.), University of Ferrara, Ferrara; Multiple..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Patti","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (M.P.A., E.P., B.H., V.Z.), University of Florence, Florence; Hospital of Gallarate (A.G.), Gallarate (VA); San Raffaele Institute (V.M., L.M., G.C.), University of Milan, Milan; Department of Neurology (F.P.), University of Catania, Catania; Besta Institute (L.L.M.), Milan; Department of Neurology (G.L.M.), University of Genova, Genova; Department of Neurology (C.S.), ASL3 Genovese, Genova; Department of Neurology (M.R.T.), University of Ferrara, Ferrara; Multiple..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"La Mantia","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (M.P.A., E.P., B.H., V.Z.), University of Florence, Florence; Hospital of Gallarate (A.G.), Gallarate (VA); San Raffaele Institute (V.M., L.M., G.C.), University of Milan, Milan; Department of Neurology (F.P.), University of Catania, Catania; Besta Institute (L.L.M.), Milan; Department of Neurology (G.L.M.), University of Genova, Genova; Department of Neurology (C.S.), ASL3 Genovese, Genova; Department of Neurology (M.R.T.), University of Ferrara, Ferrara; Multiple..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.L.","family":"Mancardi","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (M.P.A., E.P., B.H., V.Z.), University of Florence, Florence; Hospital of Gallarate (A.G.), Gallarate (VA); San Raffaele Institute (V.M., L.M., G.C.), University of Milan, Milan; Department of Neurology (F.P.), University of Catania, Catania; Besta Institute (L.L.M.), Milan; Department of Neurology (G.L.M.), University of Genova, Genova; Department of Neurology (C.S.), ASL3 Genovese, Genova; Department of Neurology (M.R.T.), University of Ferrara, Ferrara; Multiple..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Solaro","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (M.P.A., E.P., B.H., V.Z.), University of Florence, Florence; Hospital of Gallarate (A.G.), Gallarate (VA); San Raffaele Institute (V.M., L.M., G.C.), University of Milan, Milan; Department of Neurology (F.P.), University of Catania, Catania; Besta Institute (L.L.M.), Milan; Department of Neurology (G.L.M.), University of Genova, Genova; Department of Neurology (C.S.), ASL3 Genovese, Genova; Department of Neurology (M.R.T.), University of Ferrara, Ferrara; Multiple..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.R.","family":"Tola","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (M.P.A., E.P., B.H., V.Z.), University of Florence, Florence; Hospital of Gallarate (A.G.), Gallarate (VA); San Raffaele Institute (V.M., L.M., G.C.), University of Milan, Milan; Department of Neurology (F.P.), University of Catania, Catania; Besta Institute (L.L.M.), Milan; Department of Neurology (G.L.M.), University of Genova, Genova; Department of Neurology (C.S.), ASL3 Genovese, Genova; Department of Neurology (M.R.T.), University of Ferrara, Ferrara; Multiple..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Pozzilli","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (M.P.A., E.P., B.H., V.Z.), University of Florence, Florence; Hospital of Gallarate (A.G.), Gallarate (VA); San Raffaele Institute (V.M., L.M., G.C.), University of Milan, Milan; Department of Neurology (F.P.), University of Catania, Catania; Besta Institute (L.L.M.), Milan; Department of Neurology (G.L.M.), University of Genova, Genova; Department of Neurology (C.S.), ASL3 Genovese, Genova; Department of Neurology (M.R.T.), University of Ferrara, Ferrara; Multiple..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"De Giglio","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (M.P.A., E.P., B.H., V.Z.), University of Florence, Florence; Hospital of Gallarate (A.G.), Gallarate (VA); San Raffaele Institute (V.M., L.M., G.C.), University of Milan, Milan; Department of Neurology (F.P.), University of Catania, Catania; Besta Institute (L.L.M.), Milan; Department of Neurology (G.L.M.), University of Genova, Genova; Department of Neurology (C.S.), ASL3 Genovese, Genova; Department of Neurology (M.R.T.), University of Ferrara, Ferrara; Multiple..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Totaro","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (M.P.A., E.P., B.H., V.Z.), University of Florence, Florence; Hospital of Gallarate (A.G.), Gallarate (VA); San Raffaele Institute (V.M., L.M., G.C.), University of Milan, Milan; Department of Neurology (F.P.), University of Catania, Catania; Besta Institute (L.L.M.), Milan; Department of Neurology (G.L.M.), University of Genova, Genova; Department of Neurology (C.S.), ASL3 Genovese, Genova; Department of Neurology (M.R.T.), University of Ferrara, Ferrara; Multiple..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Lugaresi","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (M.P.A., E.P., B.H., V.Z.), University of Florence, Florence; Hospital of Gallarate (A.G.), Gallarate (VA); San Raffaele Institute (V.M., L.M., G.C.), University of Milan, Milan; Department of Neurology (F.P.), University of Catania, Catania; Besta Institute (L.L.M.), Milan; Department of Neurology (G.L.M.), University of Genova, Genova; Department of Neurology (C.S.), ASL3 Genovese, Genova; Department of Neurology (M.R.T.), University of Ferrara, Ferrara; Multiple..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Di Tommaso","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (M.P.A., E.P., B.H., V.Z.), University of Florence, Florence; Hospital of Gallarate (A.G.), Gallarate (VA); San Raffaele Institute (V.M., L.M., G.C.), University of Milan, Milan; Department of Neurology (F.P.), University of Catania, Catania; Besta Institute (L.L.M.), Milan; Department of Neurology (G.L.M.), University of Genova, Genova; Department of Neurology (C.S.), ASL3 Genovese, Genova; Department of Neurology (M.R.T.), University of Ferrara, Ferrara; Multiple..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Paolicelli","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (M.P.A., E.P., B.H., V.Z.), University of Florence, Florence; Hospital of Gallarate (A.G.), Gallarate (VA); San Raffaele Institute (V.M., L.M., G.C.), University of Milan, Milan; Department of Neurology (F.P.), University of Catania, Catania; Besta Institute (L.L.M.), Milan; Department of Neurology (G.L.M.), University of Genova, Genova; Department of Neurology (C.S.), ASL3 Genovese, Genova; Department of Neurology (M.R.T.), University of Ferrara, Ferrara; Multiple..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.G.","family":"Marrosu","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (M.P.A., E.P., B.H., V.Z.), University of Florence, Florence; Hospital of Gallarate (A.G.), Gallarate (VA); San Raffaele Institute (V.M., L.M., G.C.), University of Milan, Milan; Department of Neurology (F.P.), University of Catania, Catania; Besta Institute (L.L.M.), Milan; Department of Neurology (G.L.M.), University of Genova, Genova; Department of Neurology (C.S.), ASL3 Genovese, Genova; Department of Neurology (M.R.T.), University of Ferrara, Ferrara; Multiple..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Comi","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (M.P.A., E.P., B.H., V.Z.), University of Florence, Florence; Hospital of Gallarate (A.G.), Gallarate (VA); San Raffaele Institute (V.M., L.M., G.C.), University of Milan, Milan; Department of Neurology (F.P.), University of Catania, Catania; Besta Institute (L.L.M.), Milan; Department of Neurology (G.L.M.), University of Genova, Genova; Department of Neurology (C.S.), ASL3 Genovese, Genova; Department of Neurology (M.R.T.), University of Ferrara, Ferrara; Multiple..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Pellegrini","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (M.P.A., E.P., B.H., V.Z.), University of Florence, Florence; Hospital of Gallarate (A.G.), Gallarate (VA); San Raffaele Institute (V.M., L.M., G.C.), University of Milan, Milan; Department of Neurology (F.P.), University of Catania, Catania; Besta Institute (L.L.M.), Milan; Department of Neurology (G.L.M.), University of Genova, Genova; Department of Neurology (C.S.), ASL3 Genovese, Genova; Department of Neurology (M.R.T.), University of Ferrara, Ferrara; Multiple..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Trojano","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (M.P.A., E.P., B.H., V.Z.), University of Florence, Florence; Hospital of Gallarate (A.G.), Gallarate (VA); San Raffaele Institute (V.M., L.M., G.C.), University of Milan, Milan; Department of Neurology (F.P.), University of Catania, Catania; Besta Institute (L.L.M.), Milan; Department of Neurology (G.L.M.), University of Genova, Genova; Department of Neurology (C.S.), ASL3 Genovese, Genova; Department of Neurology (M.R.T.), University of Ferrara, Ferrara; Multiple..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"For the MS Study Group of the Italian Neurological Society","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_8_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199807303390501"},{"key":"e_1_3_8_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.56.10.1062"},{"key":"e_1_3_8_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2005.11.016"},{"key":"e_1_3_8_5_2","volume-title":"Avonex (interferon-\u03b2 1a): product monograph","year":"1998","unstructured":"Biogen. Avonex (interferon-\u03b2 1a): product monograph. Biogen; 1998"},{"key":"e_1_3_8_6_2","doi-asserted-by":"publisher","DOI":"10.1191\/1352458504ms1083oa"},{"key":"e_1_3_8_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.1032"},{"key":"e_1_3_8_8_2","unstructured":"ISTAT. Dimissioni dagli istituti di cura per aborto spontaneo in Italia. Available at: http:\/\/www.istat.it\/dati\/dataset\/20080415_01\/. Accessed June 15 2009"},{"key":"e_1_3_8_9_2","unstructured":"Salute MD. Certificato di assistenza al parto (CeDAP) Analisi dell'evento nascite: Anno 2005. Available at: www.ministerosalute.it\/imgs\/C_17_pubblicazioni_819_allegato.pdf. Accessed August 4 2009"},{"key":"e_1_3_8_10_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000180575.77021.c4"},{"key":"e_1_3_8_11_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000168905.97207.d0"},{"key":"e_1_3_8_12_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.33.11.1444"},{"key":"e_1_3_8_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0258(19981015)17:19<2265::AID-SIM918>3.0.CO;2-B"},{"key":"e_1_3_8_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.evalprogplan.2005.01.004"},{"key":"e_1_3_8_15_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-127-8_Part_2-199710151-00064"},{"key":"e_1_3_8_16_2","doi-asserted-by":"publisher","DOI":"10.1177\/1352458509102366"},{"key":"e_1_3_8_17_2","doi-asserted-by":"publisher","DOI":"10.1177\/1352458509106543"},{"key":"e_1_3_8_18_2","doi-asserted-by":"publisher","DOI":"10.2307\/2533848"},{"key":"e_1_3_8_19_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000275545.08382.82"},{"key":"e_1_3_8_20_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.285.4.430"},{"key":"e_1_3_8_21_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.286.10.1187"},{"key":"e_1_3_8_22_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.21102"},{"key":"e_1_3_8_23_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-008-0757-2"},{"key":"e_1_3_8_24_2","doi-asserted-by":"publisher","DOI":"10.1177\/1352458508101937"},{"key":"e_1_3_8_25_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181c3f27d"},{"key":"e_1_3_8_26_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0707943"},{"key":"e_1_3_8_27_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0008444"},{"key":"e_1_3_8_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2009.06.003"},{"key":"e_1_3_8_29_2","doi-asserted-by":"publisher","DOI":"10.2741\/2737"},{"key":"e_1_3_8_30_2","doi-asserted-by":"publisher","DOI":"10.1159\/000242165"},{"key":"e_1_3_8_31_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.37.6.1232"},{"key":"e_1_3_8_32_2","first-page":"271","article-title":"Interferon in pregnancy","volume":"11","author":"Chard T.","year":"1989","unstructured":"Chard T. Interferon in pregnancy. J Dev Physiol 1989; 11: 271\u2013 276","journal-title":"J Dev Physiol"},{"key":"e_1_3_8_33_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.82.15.5010"}],"container-title":["Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.neurology.org\/doi\/pdfdirect\/10.1212\/WNL.0b013e3181fd62bb","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,27]],"date-time":"2024-03-27T13:28:39Z","timestamp":1711546119000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.neurology.org\/doi\/10.1212\/WNL.0b013e3181fd62bb"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,11,16]]},"references-count":32,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2010,11,16]]}},"alternative-id":["10.1212\/WNL.0b013e3181fd62bb"],"URL":"https:\/\/doi.org\/10.1212\/wnl.0b013e3181fd62bb","relation":{},"ISSN":["0028-3878","1526-632X"],"issn-type":[{"value":"0028-3878","type":"print"},{"value":"1526-632X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,11,16]]}}}