{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T18:18:01Z","timestamp":1793643481031,"version":"4.5.1"},"reference-count":37,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["neurology.org"],"crossmark-restriction":true},"short-container-title":["Neurology"],"published-print":{"date-parts":[[2013,1,15]]},"DOI":"10.1212\/wnl.0b013e31827deb74","type":"journal-article","created":{"date-parts":[[2013,1,14]],"date-time":"2013-01-14T22:02:08Z","timestamp":1358200928000},"page":"276-281","update-policy":"https:\/\/doi.org\/10.1212\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":389,"title":["The spectrum of nonmotor symptoms in early Parkinson disease"],"prefix":"10.1212","volume":"80","author":[{"given":"Tien K.","family":"Khoo","sequence":"first","affiliation":[{"name":"From the Institute for Ageing and Health (T.K.K., A.J.Y., G.W.D., J.T.O., D.J. Burn) and Industrial Statistics Research Unit (S.C.), Newcastle University, Newcastle upon Tyne; Imperial College (D.J. Brooks), MRC Clinical Sciences Centre, London; and Cambridge Centre for Brain Repair (R.A.B.), Cambridge University, Cambridge, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison J.","family":"Yarnall","sequence":"additional","affiliation":[{"name":"From the Institute for Ageing and Health (T.K.K., A.J.Y., G.W.D., J.T.O., D.J. Burn) and Industrial Statistics Research Unit (S.C.), Newcastle University, Newcastle upon Tyne; Imperial College (D.J. Brooks), MRC Clinical Sciences Centre, London; and Cambridge Centre for Brain Repair (R.A.B.), Cambridge University, Cambridge, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gordon W.","family":"Duncan","sequence":"additional","affiliation":[{"name":"From the Institute for Ageing and Health (T.K.K., A.J.Y., G.W.D., J.T.O., D.J. Burn) and Industrial Statistics Research Unit (S.C.), Newcastle University, Newcastle upon Tyne; Imperial College (D.J. Brooks), MRC Clinical Sciences Centre, London; and Cambridge Centre for Brain Repair (R.A.B.), Cambridge University, Cambridge, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shirley","family":"Coleman","sequence":"additional","affiliation":[{"name":"From the Institute for Ageing and Health (T.K.K., A.J.Y., G.W.D., J.T.O., D.J. Burn) and Industrial Statistics Research Unit (S.C.), Newcastle University, Newcastle upon Tyne; Imperial College (D.J. Brooks), MRC Clinical Sciences Centre, London; and Cambridge Centre for Brain Repair (R.A.B.), Cambridge University, Cambridge, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John T.","family":"O\u2019Brien","sequence":"additional","affiliation":[{"name":"From the Institute for Ageing and Health (T.K.K., A.J.Y., G.W.D., J.T.O., D.J. Burn) and Industrial Statistics Research Unit (S.C.), Newcastle University, Newcastle upon Tyne; Imperial College (D.J. Brooks), MRC Clinical Sciences Centre, London; and Cambridge Centre for Brain Repair (R.A.B.), Cambridge University, Cambridge, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Brooks","sequence":"additional","affiliation":[{"name":"From the Institute for Ageing and Health (T.K.K., A.J.Y., G.W.D., J.T.O., D.J. Burn) and Industrial Statistics Research Unit (S.C.), Newcastle University, Newcastle upon Tyne; Imperial College (D.J. Brooks), MRC Clinical Sciences Centre, London; and Cambridge Centre for Brain Repair (R.A.B.), Cambridge University, Cambridge, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger A.","family":"Barker","sequence":"additional","affiliation":[{"name":"From the Institute for Ageing and Health (T.K.K., A.J.Y., G.W.D., J.T.O., D.J. Burn) and Industrial Statistics Research Unit (S.C.), Newcastle University, Newcastle upon Tyne; Imperial College (D.J. Brooks), MRC Clinical Sciences Centre, London; and Cambridge Centre for Brain Repair (R.A.B.), Cambridge University, Cambridge, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Burn","sequence":"additional","affiliation":[{"name":"From the Institute for Ageing and Health (T.K.K., A.J.Y., G.W.D., J.T.O., D.J. Burn) and Industrial Statistics Research Unit (S.C.), Newcastle University, Newcastle upon Tyne; Imperial College (D.J. Brooks), MRC Clinical Sciences Centre, London; and Cambridge Centre for Brain Repair (R.A.B.), Cambridge University, Cambridge, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_7_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.22643"},{"key":"e_1_3_7_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.21586"},{"key":"e_1_3_7_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2011.10.015"},{"key":"e_1_3_7_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.69.3.308"},{"key":"e_1_3_7_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.23462"},{"key":"e_1_3_7_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.22868"},{"key":"e_1_3_7_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.21813"},{"key":"e_1_3_7_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2008.166959"},{"key":"e_1_3_7_10_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000338632.00552.cb"},{"key":"e_1_3_7_11_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000180516.69442.95"},{"key":"e_1_3_7_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.23387"},{"key":"e_1_3_7_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.24041"},{"key":"e_1_3_7_14_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2005.081711"},{"key":"e_1_3_7_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20844"},{"key":"e_1_3_7_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2011.08.013"},{"key":"e_1_3_7_17_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.55.3.181"},{"key":"e_1_3_7_18_2","volume-title":"Diagnostic and Statistical Manual of Mental Disorders: 4th edition (text revised)","author":"American Psychiatric Association","year":"2000","unstructured":"American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders: 4th edition (text revised). Washington, DC: American Psychiatric Association; 2000."},{"key":"e_1_3_7_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.10459"},{"key":"e_1_3_7_20_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.17.5.427"},{"key":"e_1_3_7_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.22340"},{"key":"e_1_3_7_22_2","first-page":"A1077","article-title":"Postural instability and gait difficulty scores from the MDS-UPDRS","volume":"26","author":"Stebbins GT","year":"2011","unstructured":"Stebbins GT, Goetz CG, Burn DJ, Jankovic J, Tilley BC. Postural instability and gait difficulty scores from the MDS-UPDRS. Mov Disord 2011;26(suppl 2):A1077. Abstract.","journal-title":"Mov Disord"},{"key":"e_1_3_7_23_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.40.10.1529"},{"key":"e_1_3_7_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3956(75)90026-6"},{"key":"e_1_3_7_25_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2005.53221.x"},{"key":"e_1_3_7_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3956(82)90033-4"},{"key":"e_1_3_7_27_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-010-0665-2"},{"key":"e_1_3_7_28_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-010-0664-3"},{"key":"e_1_3_7_29_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.58.6.756-a"},{"key":"e_1_3_7_30_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.23919"},{"key":"e_1_3_7_31_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-410x.2001.02228.x"},{"key":"e_1_3_7_32_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.21453"},{"key":"e_1_3_7_33_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.23331"},{"key":"e_1_3_7_34_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awp068"},{"key":"e_1_3_7_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(06)70441-0"},{"key":"e_1_3_7_36_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.24939"},{"key":"e_1_3_7_37_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2008.149195"},{"key":"e_1_3_7_38_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25086"}],"container-title":["Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.neurology.org\/doi\/pdfdirect\/10.1212\/WNL.0b013e31827deb74","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,28]],"date-time":"2024-03-28T13:08:15Z","timestamp":1711631295000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.neurology.org\/doi\/10.1212\/WNL.0b013e31827deb74"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1,15]]},"references-count":37,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,1,15]]}},"alternative-id":["10.1212\/WNL.0b013e31827deb74"],"URL":"https:\/\/doi.org\/10.1212\/wnl.0b013e31827deb74","relation":{},"ISSN":["0028-3878","1526-632X"],"issn-type":[{"value":"0028-3878","type":"print"},{"value":"1526-632X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,1,15]]}}}