{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T11:30:53Z","timestamp":1790163053962,"version":"4.1.0"},"reference-count":0,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":["neurology.org"],"crossmark-restriction":true},"short-container-title":["Neurology"],"published-print":{"date-parts":[[1993,12]]},"DOI":"10.1212\/wnl.43.12.2685","type":"journal-article","created":{"date-parts":[[2012,5,13]],"date-time":"2012-05-13T13:05:52Z","timestamp":1336914352000},"page":"2685-2685","update-policy":"https:\/\/doi.org\/10.1212\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":59,"title":["Catechol\u2010O\u2010methyltransferase inhibitor tolcapone prolongs levodopa\/carbidopa action in parkinsonian patients"],"prefix":"10.1212","volume":"43","author":[{"given":"J. W.","family":"Roberts","sequence":"first","affiliation":[{"name":"Experimental Therapeutics Branch (Drs. Roberts, Cora-Locatelli, Bravi, Mouradian, and Chase), National Institute of Neurological Disorders and Stroke, and the Pharmacokinetics Laboratory (Dr. Amantea), Pharmaceutical Development Service, Pharmacy Department of the Clinical Center, National Institutes of Health, Bethesda, MD."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Cora-Locatelli","sequence":"additional","affiliation":[{"name":"Experimental Therapeutics Branch (Drs. Roberts, Cora-Locatelli, Bravi, Mouradian, and Chase), National Institute of Neurological Disorders and Stroke, and the Pharmacokinetics Laboratory (Dr. Amantea), Pharmaceutical Development Service, Pharmacy Department of the Clinical Center, National Institutes of Health, Bethesda, MD."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Bravi","sequence":"additional","affiliation":[{"name":"Experimental Therapeutics Branch (Drs. Roberts, Cora-Locatelli, Bravi, Mouradian, and Chase), National Institute of Neurological Disorders and Stroke, and the Pharmacokinetics Laboratory (Dr. Amantea), Pharmaceutical Development Service, Pharmacy Department of the Clinical Center, National Institutes of Health, Bethesda, MD."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. A.","family":"Amantea","sequence":"additional","affiliation":[{"name":"Experimental Therapeutics Branch (Drs. Roberts, Cora-Locatelli, Bravi, Mouradian, and Chase), National Institute of Neurological Disorders and Stroke, and the Pharmacokinetics Laboratory (Dr. Amantea), Pharmaceutical Development Service, Pharmacy Department of the Clinical Center, National Institutes of Health, Bethesda, MD."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. M.","family":"Mouradian","sequence":"additional","affiliation":[{"name":"Experimental Therapeutics Branch (Drs. Roberts, Cora-Locatelli, Bravi, Mouradian, and Chase), National Institute of Neurological Disorders and Stroke, and the Pharmacokinetics Laboratory (Dr. Amantea), Pharmaceutical Development Service, Pharmacy Department of the Clinical Center, National Institutes of Health, Bethesda, MD."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T. N.","family":"Chase","sequence":"additional","affiliation":[{"name":"Experimental Therapeutics Branch (Drs. Roberts, Cora-Locatelli, Bravi, Mouradian, and Chase), National Institute of Neurological Disorders and Stroke, and the Pharmacokinetics Laboratory (Dr. Amantea), Pharmaceutical Development Service, Pharmacy Department of the Clinical Center, National Institutes of Health, Bethesda, MD."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","container-title":["Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.neurology.org\/doi\/pdfdirect\/10.1212\/WNL.43.12.2685","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,27]],"date-time":"2024-03-27T15:09:45Z","timestamp":1711552185000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.neurology.org\/doi\/10.1212\/WNL.43.12.2685"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,12]]},"references-count":0,"journal-issue":{"issue":"12","published-print":{"date-parts":[[1993,12]]}},"alternative-id":["10.1212\/WNL.43.12.2685"],"URL":"https:\/\/doi.org\/10.1212\/wnl.43.12.2685","relation":{},"ISSN":["0028-3878","1526-632X"],"issn-type":[{"value":"0028-3878","type":"print"},{"value":"1526-632X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1993,12]]}}}