{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T19:53:35Z","timestamp":1760385215396},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["neurology.org"],"crossmark-restriction":true},"short-container-title":["Neurology"],"published-print":{"date-parts":[[1996,1]]},"DOI":"10.1212\/wnl.46.1.126","type":"journal-article","created":{"date-parts":[[2012,5,13]],"date-time":"2012-05-13T13:17:32Z","timestamp":1336915052000},"page":"126-129","update-policy":"http:\/\/dx.doi.org\/10.1212\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":27,"title":["Increased risk of familial late-onset Alzheimer's disease in women"],"prefix":"10.1212","volume":"46","author":[{"given":"H.","family":"Payami","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Montee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Grimslid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Shattuc","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Kaye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.42.1.1"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410300103"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.40.1.1"},{"key":"e_1_3_1_5_2","unstructured":"Katzman R. Alzheimer disease. New York: Raven Press 1994."},{"key":"e_1_3_1_6_2","first-page":"5","volume":"43","year":"1993","unstructured":"Bachman DL, Wolf PA, Linn RT, et al. Incidence of dementia and probable Alzheimer's disease in a general population: the Framingham Study. Neurology 1993;43:515-519.","journal-title":"Neurology"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.38.1.9"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410250103"},{"key":"e_1_3_1_9_2","first-page":"7","volume":"22","year":"1987","unstructured":"Schoenberg BS, Kokmen E, Okazaki H. Alzheimer's disease and other dementing illnesses in a defined United States population: incidence rates and clinical features. Ann Neurol 1987;22:724-729.","journal-title":"Ann Neurol"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410230102"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.39.1.1"},{"key":"e_1_3_1_12_2","first-page":"4","volume":"39","year":"1991","unstructured":"Edwards JK, Larson EB, Hughes JP, Kukull WA. Are there clinical and epidemiological differences between familial and non-familial Alzheimer's disease? J Am Geriatr Soc 1991;39:477-483.","journal-title":"Are there clinical and epidemiological differences between familial and non-familial Alzheimer's disease? J Am Geriatr Soc"},{"key":"e_1_3_1_13_2","first-page":"6","volume":"54","year":"1994","unstructured":"Payami H, Montee K, Kaye J. Evidence for familial factors that protect against dementia and outweigh the effect of increasing age. Am J Hum Genet 1994;54:650-657.","journal-title":"Am J Hum Genet"},{"key":"e_1_3_1_14_2","first-page":"1","volume":"43","year":"1993","unstructured":"Saunders AM, Strittmatter WJ, Schmechel D, et al. Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease. Neurology 1993;43:1467-1472.","journal-title":"Neurology"},{"key":"e_1_3_1_15_2","first-page":"6","volume":"54","year":"1994","unstructured":"Yu C-E, Payami H, Olson JM, et al. Apolipoprotein E\/CI\/CII gene cluster and late-onset Alzheimer disease. Am J Hum Genet 1994;54:631-642.","journal-title":"Am J Hum Genet"},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.261.5117.9"},{"key":"e_1_3_1_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(93)91879-Q"},{"key":"e_1_3_1_18_2","first-page":"6","volume":"30","year":"1993","unstructured":"van Duijn CM, Farrer LA, Cupples LA, Hayman A. Genetic transmission of Alzheimer's disease among families in a Dutch population based study. J Med Genet 1993;30:640-646.","journal-title":"J Med Genet"},{"key":"e_1_3_1_19_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.44.1.1"},{"key":"e_1_3_1_20_2","first-page":"2","volume":"38","year":"1988","unstructured":"Breitner JCS, Silverman JM, Mohs RC, Davis KL. Familial aggregation in Alzheimer's disease: comparison of risk among male and female relatives in successive generations. Neurology 1988;38:207-212.","journal-title":"Neurology"},{"key":"e_1_3_1_21_2","first-page":"5","volume":"17","year":"1994","unstructured":"Poirier J. Apolipoprotein E in animal models of CNS injury and in Alzheimer's disease. Trends Neurosci 1994;17:525-580.","journal-title":"Trends Neurosci"},{"key":"e_1_3_1_22_2","first-page":"1","volume":"55","year":"1994","unstructured":"Reilly SL, Ferrell RE, Sing CF. The gender-specific apolipoprotein E genotype influence on the distribution of plasma lipids and apolipoproteins in the population of Rochester, MN. III. Correlations and covariances. Am J Hum Genet 1994;55:1001-1018.","journal-title":"Am J Hum Genet"},{"key":"e_1_3_1_23_2","first-page":"1","volume":"271","year":"1994","unstructured":"Payami H, Montee KR, Kaye JA, et al. Alzheimer's disease, apolipoprotein E4, and gender. JAMA 1994;271:1316-1317.","journal-title":"JAMA"},{"key":"e_1_3_1_24_2","first-page":"9","volume":"34","year":"1984","unstructured":"McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984;34:939-944.","journal-title":"Neurology"},{"key":"e_1_3_1_25_2","first-page":"9","volume":"51","year":"1992","unstructured":"Kamino K, Orr HT, Payami H, et al. Linkage and mutational analysis of familial Alzheimer disease kindreds for the APP gene region. Am J Hum Genet 1992;51:998-1014.","journal-title":"Am J Hum Genet"},{"key":"e_1_3_1_26_2","first-page":"6","volume":"53","year":"1994","unstructured":"Schellenberg GD, Payami H, Wijsman EM, et al. Chromosome 14 and late-onset familial Alzheimer's disease. Am J Hum Genet 1994;53:619-628.","journal-title":"Am J Hum Genet"},{"key":"e_1_3_1_27_2","first-page":"4","volume":"17","year":"1992","unstructured":"Phillips SM, Sherwin BB. Effects of estrogen on memory function in surgically menopausal women. Psychoneuroendocrinology 1992;17:485-495.","journal-title":"Psychoneuroendocrinology"},{"key":"e_1_3_1_28_2","first-page":"2","volume":"269","year":"1993","unstructured":"Barrett-Conner E, Kritz-Silverstein D. Estrogen replacement therapy and cognitive function in older women. JAMA 1993;269:2637-2641.","journal-title":"JAMA"},{"key":"e_1_3_1_29_2","first-page":"9","volume":"42","year":"1994","unstructured":"Robinson D, Friedman L, Marcus R, Tinklenberg J, Yesavage J. Estrogen replacement therapy and memory in older women. J Am Geriatr Soc 1994;42:919-922.","journal-title":"J Am Geriatr Soc"},{"key":"e_1_3_1_30_2","first-page":"2","volume":"140","year":"1994","unstructured":"Brenner DE, Kukull WA, Stergachis A, et al. Postmenopausal estrogen replacement therapy and the risk of Alzheimer's disease: a population based case control study. Am J Epidemiol 1994;140:262-267.","journal-title":"Am J Epidemiol"},{"key":"e_1_3_1_31_2","first-page":"2","volume":"140","year":"1994","unstructured":"Paganini-Hill A, Henderson V. Estrogen deficiency and risk of Alzheimer's disease. Am J Epidemiol 1994;140:256-261.","journal-title":"Am J Epidemiol"}],"container-title":["Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.neurology.org\/doi\/pdfdirect\/10.1212\/WNL.46.1.126","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,27]],"date-time":"2024-03-27T13:34:43Z","timestamp":1711546483000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.neurology.org\/doi\/10.1212\/WNL.46.1.126"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,1]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1996,1]]}},"alternative-id":["10.1212\/WNL.46.1.126"],"URL":"https:\/\/doi.org\/10.1212\/wnl.46.1.126","relation":{},"ISSN":["0028-3878","1526-632X"],"issn-type":[{"value":"0028-3878","type":"print"},{"value":"1526-632X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,1]]}}}