{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T10:16:40Z","timestamp":1778840200564,"version":"3.51.4"},"reference-count":25,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["neurology.org"],"crossmark-restriction":true},"short-container-title":["Neurology"],"published-print":{"date-parts":[[1996,7]]},"DOI":"10.1212\/wnl.47.1.68","type":"journal-article","created":{"date-parts":[[2012,5,13]],"date-time":"2012-05-13T13:21:25Z","timestamp":1336915285000},"page":"68-76","update-policy":"https:\/\/doi.org\/10.1212\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":96,"title":["Prognosis for total control of complex partial and secondarily generalized tonic clonic seizures"],"prefix":"10.1212","volume":"47","author":[{"given":"Richard H.","family":"Mattson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joyce A.","family":"Cramer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph F.","family":"Collins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198507043130101"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199207023270102"},{"key":"e_1_3_1_4_2","first-page":"6","volume":"48","year":"1985","unstructured":"Callaghan N, Kenny RA, O'Neil B, et al. A prospective study between carbamazepine, phenytoin and sodium valproate as monotherapy in previously untreated and recently diagnosed patients with epilepsy. J Neurol Neurosurg Psychiatry 1985;48:639-644.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.48.1.1"},{"key":"e_1_3_1_6_2","first-page":"5","volume":"45","year":"1982","unstructured":"Turnbull DM, Rawlins MD, Weightman, Chadwick DW. A comparison of phenytoin and valproate in previously untreated adult epileptic patients. J Neurol Neurosurg Psychiatry 1982;45:55-59.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"e_1_3_1_7_2","first-page":"4","volume":"58","year":"1995","unstructured":"Heller AJ, Chesterman P, Elwes RDC, et al. Phenobarbitone, phenytoin, carbamazepine, or valproate for newly diagnosed adult epilepsy: a randomized comparative trial. J Neurol Neurosurg Psychiatry 1995;58:40-50.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.57.Suppl.6"},{"key":"e_1_3_1_9_2","doi-asserted-by":"crossref","unstructured":"Mattson RH Cramer JA Delgado-Escueta AV et al. A design for the prospective evaluation of the efficacy and toxicity of antiepileptic drugs in adults. Neurology 1983;33(suppl 1):14-25.","DOI":"10.1212\/WNL.33.3_Suppl_1.14"},{"key":"e_1_3_1_10_2","doi-asserted-by":"crossref","unstructured":"Cramer JA Smith DB Mattson RH et al. A method of quantification for the evaluation of antiepileptic drug therapy. Neurology 1983;33(suppl 1):26-37.","DOI":"10.1212\/WNL.33.3_Suppl_1.26"},{"key":"e_1_3_1_11_2","first-page":"4","volume":"22","year":"1981","unstructured":"Commission on Classification and Terminology of the International League Against Epilepsy. Proposal for revised clinical and electroencephalographic classification of epileptic seizures. Epilepsia 1981;22:489-501.","journal-title":"Epilepsia"},{"key":"e_1_3_1_12_2","doi-asserted-by":"crossref","unstructured":"Mattson RH Cramer JA. Quantitative assessment of adverse drug effects. In: Meinardi H Cramer JA Baker GA Martins da Silva A eds. Quantitative assessment of epilepsy care: clinimetric applications. New York: Pergamon Press 1993:123-135.","DOI":"10.1007\/978-1-4615-2990-3_14"},{"key":"e_1_3_1_13_2","doi-asserted-by":"crossref","unstructured":"Cramer JA Mattson RH. Quantitative approaches to seizure severity. In: Meinardi H Cramer JA Baker GA Martins da Silva A eds. Quantitative assessment of epilepsy care: clinimetric applications. New York: Pergamon Press 1993:55-72.","DOI":"10.1007\/978-1-4615-2990-3_7"},{"key":"e_1_3_1_14_2","first-page":"4","volume":"9","year":"1988","unstructured":"Cramer JA, Collins JF, Mattson RH. Can categorization of patient background problems be used to determine early termination in a clinical trial? Control Clin Trials 1988;9:47-63.","journal-title":"Can categorization of patient background problems be used to determine early termination in a clinical trial? Control Clin Trials"},{"key":"e_1_3_1_15_2","first-page":"6","volume":"8","year":"1958","unstructured":"Cutler SJ, Ederer F. Maximum utilization of the life table method in analyzing survival. J Chron Dis 1958;8:699-712.","journal-title":"J Chron Dis"},{"key":"e_1_3_1_16_2","unstructured":"Bendetti J Yuen K Young L. Life tables and survivor functions. In: Dixon WJ Brown MB Engleman L Jennrich RI ed. BMDP Statistical Software manual vol 2. Berkeley CA: University of California Press 1990:739-768."},{"key":"e_1_3_1_17_2","first-page":"9","volume":"311","year":"1984","unstructured":"Elwes RDC, Johnson AL, Shorvon SD, Reynolds EH. The prognosis for seizure control in newly diagnosed epilepsy. N Engl J Med 1984;311:944-947.","journal-title":"N Engl J Med"},{"key":"e_1_3_1_18_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.85.1.1"},{"key":"e_1_3_1_19_2","first-page":"4","volume":"43","year":"1993","unstructured":"First Seizure Trial Group. Randomized clinical trial on the efficacy of antiepileptic drugs in reducing the risk of relapse after a first unprovoked tonic-clonic seizure. Neurology 1993;43:478-483.","journal-title":"Neurology"},{"key":"e_1_3_1_20_2","first-page":"9","volume":"41","year":"1991","unstructured":"Berg AT, Shinnar S. The risk of seizure recurrence following a first unprovoked seizure. Neurology 1991;41:965-972.","journal-title":"Neurology"},{"key":"e_1_3_1_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(90)91517-E"},{"key":"e_1_3_1_22_2","unstructured":"DeSilva M McGowan M Neville BR et al. A prospective randomised comparative monotherapy clinical trial in childhood epilepsy. In: Chadwick E ed. Proceedings of the Fourth International Symposium on Sodium Valproate and Epilepsy. London: Royal Society of Medicine Services 1989:81-86."},{"key":"e_1_3_1_23_2","first-page":"2","volume":"29","year":"1988","unstructured":"Beghi E, Tognoni G (Collaborative Group for the Study of Epilepsy principal investigators). Prognosis of epilepsy in newly referred patients: a multicenter prospective study. Epilepsia 1988;29:236-243.","journal-title":"Epilepsia"},{"key":"e_1_3_1_24_2","first-page":"9","volume":"28","year":"1987","unstructured":"Reynolds EH. Early treatment and prognosis of epilepsy. Epilepsia 1987;28:97-106.","journal-title":"Epilepsia"},{"key":"e_1_3_1_25_2","first-page":"7","volume":"29","year":"1988","unstructured":"Mattson RH, Cramer JA, Collins JF, and the VA Epilepsy Cooperative Study Group. Time of next seizure after starting an antiepileptic drug (abstract). Epilepsia 1988;29:704.","journal-title":"Epilepsia"},{"key":"e_1_3_1_26_2","first-page":"6","volume":"31","year":"1990","unstructured":"Mattson RH, Cramer JA, and the VA Epilepsy Cooperative Study Group. Seizure remission after active epilepsy. Epilepsia 1990;31:648.","journal-title":"Epilepsia"}],"container-title":["Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.neurology.org\/doi\/pdfdirect\/10.1212\/WNL.47.1.68","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,27]],"date-time":"2024-03-27T10:29:53Z","timestamp":1711535393000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.neurology.org\/doi\/10.1212\/WNL.47.1.68"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,7]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1996,7]]}},"alternative-id":["10.1212\/WNL.47.1.68"],"URL":"https:\/\/doi.org\/10.1212\/wnl.47.1.68","relation":{},"ISSN":["0028-3878","1526-632X"],"issn-type":[{"value":"0028-3878","type":"print"},{"value":"1526-632X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,7]]}}}