{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T14:28:36Z","timestamp":1776954516302,"version":"3.51.4"},"reference-count":41,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurology"],"published-print":{"date-parts":[[1998,8]]},"DOI":"10.1212\/wnl.51.2.371","type":"journal-article","created":{"date-parts":[[2012,5,13]],"date-time":"2012-05-13T13:35:18Z","timestamp":1336916118000},"page":"371-378","source":"Crossref","is-referenced-by-count":111,"title":["<i>Campylobacter jejuni<\/i>\n            lipopolysaccharides in Guillain-Barre\u0301 syndrome"],"prefix":"10.1212","volume":"51","author":[{"given":"K. A.","family":"Sheikh","sequence":"first","affiliation":[{"name":"From the Department of Neurology (Drs. Sheikh, Ho, Cornblath, McKhann, and Griffin), Johns Hopkins University School of Medicine, Baltimore; the Johns Hopkins University Zanvyl Krieger Mind-Brain Institute (Dr. McKhann), Baltimore, MD; the Departments of Pathology and Laboratory Medicine (Dr. Nachamkin and H. Ung) and Neurology (Dr. Asbury), University of Pennsylvania School of Medicine, Philadelphia, PA; the Department of Neurology (H.J. Willison and J. Veitch), Institute of Neurological Sciences,..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Nachamkin","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (Drs. Sheikh, Ho, Cornblath, McKhann, and Griffin), Johns Hopkins University School of Medicine, Baltimore; the Johns Hopkins University Zanvyl Krieger Mind-Brain Institute (Dr. McKhann), Baltimore, MD; the Departments of Pathology and Laboratory Medicine (Dr. Nachamkin and H. Ung) and Neurology (Dr. Asbury), University of Pennsylvania School of Medicine, Philadelphia, PA; the Department of Neurology (H.J. Willison and J. Veitch), Institute of Neurological Sciences,..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. W.","family":"Ho","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (Drs. Sheikh, Ho, Cornblath, McKhann, and Griffin), Johns Hopkins University School of Medicine, Baltimore; the Johns Hopkins University Zanvyl Krieger Mind-Brain Institute (Dr. McKhann), Baltimore, MD; the Departments of Pathology and Laboratory Medicine (Dr. Nachamkin and H. Ung) and Neurology (Dr. Asbury), University of Pennsylvania School of Medicine, Philadelphia, PA; the Department of Neurology (H.J. Willison and J. Veitch), Institute of Neurological Sciences,..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. J.","family":"Willison","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (Drs. Sheikh, Ho, Cornblath, McKhann, and Griffin), Johns Hopkins University School of Medicine, Baltimore; the Johns Hopkins University Zanvyl Krieger Mind-Brain Institute (Dr. McKhann), Baltimore, MD; the Departments of Pathology and Laboratory Medicine (Dr. Nachamkin and H. Ung) and Neurology (Dr. Asbury), University of Pennsylvania School of Medicine, Philadelphia, PA; the Department of Neurology (H.J. Willison and J. Veitch), Institute of Neurological Sciences,..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Veitch","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (Drs. Sheikh, Ho, Cornblath, McKhann, and Griffin), Johns Hopkins University School of Medicine, Baltimore; the Johns Hopkins University Zanvyl Krieger Mind-Brain Institute (Dr. McKhann), Baltimore, MD; the Departments of Pathology and Laboratory Medicine (Dr. Nachamkin and H. Ung) and Neurology (Dr. Asbury), University of Pennsylvania School of Medicine, Philadelphia, PA; the Department of Neurology (H.J. Willison and J. Veitch), Institute of Neurological Sciences,..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Ung","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (Drs. Sheikh, Ho, Cornblath, McKhann, and Griffin), Johns Hopkins University School of Medicine, Baltimore; the Johns Hopkins University Zanvyl Krieger Mind-Brain Institute (Dr. McKhann), Baltimore, MD; the Departments of Pathology and Laboratory Medicine (Dr. Nachamkin and H. Ung) and Neurology (Dr. Asbury), University of Pennsylvania School of Medicine, Philadelphia, PA; the Department of Neurology (H.J. Willison and J. Veitch), Institute of Neurological Sciences,..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Nicholson","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (Drs. Sheikh, Ho, Cornblath, McKhann, and Griffin), Johns Hopkins University School of Medicine, Baltimore; the Johns Hopkins University Zanvyl Krieger Mind-Brain Institute (Dr. McKhann), Baltimore, MD; the Departments of Pathology and Laboratory Medicine (Dr. Nachamkin and H. Ung) and Neurology (Dr. Asbury), University of Pennsylvania School of Medicine, Philadelphia, PA; the Department of Neurology (H.J. Willison and J. Veitch), Institute of Neurological Sciences,..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. Y.","family":"Li","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (Drs. Sheikh, Ho, Cornblath, McKhann, and Griffin), Johns Hopkins University School of Medicine, Baltimore; the Johns Hopkins University Zanvyl Krieger Mind-Brain Institute (Dr. McKhann), Baltimore, MD; the Departments of Pathology and Laboratory Medicine (Dr. Nachamkin and H. Ung) and Neurology (Dr. Asbury), University of Pennsylvania School of Medicine, Philadelphia, PA; the Department of Neurology (H.J. Willison and J. Veitch), Institute of Neurological Sciences,..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. S.","family":"Wu","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (Drs. Sheikh, Ho, Cornblath, McKhann, and Griffin), Johns Hopkins University School of Medicine, Baltimore; the Johns Hopkins University Zanvyl Krieger Mind-Brain Institute (Dr. McKhann), Baltimore, MD; the Departments of Pathology and Laboratory Medicine (Dr. Nachamkin and H. Ung) and Neurology (Dr. Asbury), University of Pennsylvania School of Medicine, Philadelphia, PA; the Department of Neurology (H.J. Willison and J. Veitch), Institute of Neurological Sciences,..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B. Q.","family":"Shen","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (Drs. Sheikh, Ho, Cornblath, McKhann, and Griffin), Johns Hopkins University School of Medicine, Baltimore; the Johns Hopkins University Zanvyl Krieger Mind-Brain Institute (Dr. McKhann), Baltimore, MD; the Departments of Pathology and Laboratory Medicine (Dr. Nachamkin and H. Ung) and Neurology (Dr. Asbury), University of Pennsylvania School of Medicine, Philadelphia, PA; the Department of Neurology (H.J. Willison and J. Veitch), Institute of Neurological Sciences,..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. R.","family":"Cornblath","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (Drs. Sheikh, Ho, Cornblath, McKhann, and Griffin), Johns Hopkins University School of Medicine, Baltimore; the Johns Hopkins University Zanvyl Krieger Mind-Brain Institute (Dr. McKhann), Baltimore, MD; the Departments of Pathology and Laboratory Medicine (Dr. Nachamkin and H. Ung) and Neurology (Dr. Asbury), University of Pennsylvania School of Medicine, Philadelphia, PA; the Department of Neurology (H.J. Willison and J. Veitch), Institute of Neurological Sciences,..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. K.","family":"Asbury","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (Drs. Sheikh, Ho, Cornblath, McKhann, and Griffin), Johns Hopkins University School of Medicine, Baltimore; the Johns Hopkins University Zanvyl Krieger Mind-Brain Institute (Dr. McKhann), Baltimore, MD; the Departments of Pathology and Laboratory Medicine (Dr. Nachamkin and H. Ung) and Neurology (Dr. Asbury), University of Pennsylvania School of Medicine, Philadelphia, PA; the Department of Neurology (H.J. Willison and J. Veitch), Institute of Neurological Sciences,..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. M.","family":"McKhann","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (Drs. Sheikh, Ho, Cornblath, McKhann, and Griffin), Johns Hopkins University School of Medicine, Baltimore; the Johns Hopkins University Zanvyl Krieger Mind-Brain Institute (Dr. McKhann), Baltimore, MD; the Departments of Pathology and Laboratory Medicine (Dr. Nachamkin and H. Ung) and Neurology (Dr. Asbury), University of Pennsylvania School of Medicine, Philadelphia, PA; the Department of Neurology (H.J. Willison and J. Veitch), Institute of Neurological Sciences,..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. W.","family":"Griffin","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (Drs. Sheikh, Ho, Cornblath, McKhann, and Griffin), Johns Hopkins University School of Medicine, Baltimore; the Johns Hopkins University Zanvyl Krieger Mind-Brain Institute (Dr. McKhann), Baltimore, MD; the Departments of Pathology and Laboratory Medicine (Dr. Nachamkin and H. Ung) and Neurology (Dr. Asbury), University of Pennsylvania School of Medicine, Philadelphia, PA; the Department of Neurology (H.J. Willison and J. Veitch), Institute of Neurological Sciences,..."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_1_2_2","first-page":"4","volume":"13","year":"1992","unstructured":"Yuki N, Handa S, Taki T, Kasama T, Takahashi M, Saito K. Cross-reactive antigen between nervous tissue and a bacterium elicits Guillain-Barr\u00e9 syndrome: molecular mimicry between gangliocide GM1 and lipopolysaccharide from Penner's serotype 19 of Campylobacter jejuni. Biomed Res 1992;13:451-453.","journal-title":"Biomed Res"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410350104"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/165.1.1"},{"key":"e_1_3_1_5_2","first-page":"9","volume":"16","year":"1992","unstructured":"Yuki N, Sato S, Fujimoto S, Yamada Y, Kinoshita A, Itoh T. Serotype of Campylobacter jejuni, HLA, and the Guillain-Barr\u00e9 syndrome. Muscle Nerve 1992;16:968-969.","journal-title":"Muscle Nerve"},{"key":"e_1_3_1_6_2","first-page":"2","volume":"33","year":"1993","unstructured":"Kuroki S, Saida T, Nukina M, Haruta T, Yoshioka M, Kobayashi Y, Nakanishi H. Campylobacter jejuni strains from patients with Guillain-Barr\u00e9 syndrome belong mostly to Penner serogroup 19 and contain beta-N-acetylglucosamine residues. Ann Neurol 1993;33:243-247.","journal-title":"Ann Neurol"},{"key":"e_1_3_1_7_2","first-page":"2","volume":"62","year":"1994","unstructured":"Aspinall GO, Fujimoto S, McDonald AG, et al. Lipopolysaccharides from Campylobacter jejuni associated with Guillain-Barr\u00e9 syndrome patients mimic human gangliosides in structure. Infect Immun 1994;62:2122-2125.","journal-title":"Infect Immun"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410380102"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi00167a001"},{"key":"e_1_3_1_10_2","first-page":"5","volume":"118","year":"1995","unstructured":"Ho TW, Mishu B, Li CY, et al. Guillain-Barr\u00e9 syndrome in northern China: relationship to Campylobacter jejuni infection and anti-glycolipid antibodies. Brain 1995;118:597-605.","journal-title":"Brain"},{"key":"e_1_3_1_11_2","first-page":"8","volume":"38","year":"1995","unstructured":"Rees JH, Gregson NA, Hughes RAC. Anti-ganglioside GM1 antibodies in Guillain-Barr\u00e9 syndrome and their relationship to Campylobacter jejuni infection. Ann Neurol 1995;38:809-816.","journal-title":"Ann Neurol"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199507063330101"},{"key":"e_1_3_1_13_2","unstructured":"Epidemiology of Campylobacter jejuni infections in the United States and other industrialized nations. In: Tauxe RV Nachamkin I Blaser MJ Tompkins LS eds. Campylobacter jejuni : current status and future trends. Washington DC: American Society for Microbiology 1992:9-19."},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/17.1.1"},{"key":"e_1_3_1_15_2","first-page":"4","volume":"35","year":"1982","unstructured":"Bolton FJ, Robertson L. A selective medium for isolating Campylobacter jejuni\/coli. J Clin Pathol 1982;35:462-467.","journal-title":"J Clin Pathol"},{"key":"e_1_3_1_16_2","first-page":"9","volume":"37","year":"1984","unstructured":"Hutchinson DN, Bolton FJ. Improved blood-free selective medium for the isolation of Campylobacter jejuni from faecal specimens. J Clin Pathol 1984;37:956-957.","journal-title":"J Clin Pathol"},{"key":"e_1_3_1_17_2","first-page":"7","volume":"48","year":"1997","unstructured":"Ho TW, Hsieh S-T, Nachamkin I, et al. Motor nerve terminal degeneration provides a potential mechanism for rapid recovery in acute motor axonal neuropathy after Campylobacter infection. Neurology 1997;48:717-724.","journal-title":"Neurology"},{"key":"e_1_3_1_18_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.12.1.7-9.1980"},{"key":"e_1_3_1_19_2","first-page":"7","volume":"15","year":"1982","unstructured":"Lior H, Woodward DL, Edgar JA, Laroche LJ, Gill P. Serotyping of Campylobacter jejuni by slide agglutination based on heat labile antigenic factors. J Clin Microbiol 1982;15:761-768.","journal-title":"J Clin Microbiol"},{"key":"e_1_3_1_20_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.31.1.1-8.1993"},{"key":"e_1_3_1_21_2","first-page":"2","volume":"34","year":"1996","unstructured":"Nachamkin I, Ung H, Patton CM. Analysis of HL and O serotypes of Campylobacter by the flagellin gene typing system. J Clin Microbiol 1996;34:277-281.","journal-title":"J Clin Microbiol"},{"key":"e_1_3_1_22_2","first-page":"8","volume":"5","year":"1965","unstructured":"Westphal O, Jann K. Bacterial lipopolysaccharides: extraction with phenol-water and further applications of the procedure. Methods Carbohydr Chem 1965;5:83-91.","journal-title":"Methods Carbohydr Chem"},{"key":"e_1_3_1_23_2","first-page":"2","volume":"334","year":"1988","unstructured":"Stevens TL, Bossie A, Sanders VM, et al. Regulation of antibody isotype secretion by subsets of antigen-specific helper T cells. Nature 1988;334:255-258.","journal-title":"Nature"},{"key":"e_1_3_1_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(82)90656-X"},{"key":"e_1_3_1_25_2","first-page":"9","volume":"118","year":"1993","unstructured":"Mishu B, Ilyas AA, Koski CL, et al. Serologic evidence of previous Campylobacter jejuni infection in patients with the Guillain-Barr\u00e9 syndrome. Ann Intern Med 1993;118:947-953.","journal-title":"Ann Intern Med"},{"key":"e_1_3_1_26_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410350704"},{"key":"e_1_3_1_27_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410420103"},{"key":"e_1_3_1_28_2","first-page":"2","volume":"73","year":"1997","unstructured":"Gregson NA, Rees JH, Hughes RAC. Reactivity of serum IgG anti-GM1 ganglioside antibodies with the lipopolysaccharide fractions of Campylobacter jejuni isolates from patients with Guillain-Barr\u00e9 syndrome (GBS). J Neuroimmunol 1997;73:28-36.","journal-title":"J Neuroimmunol"},{"key":"e_1_3_1_29_2","first-page":"8","volume":"170","year":"1994","unstructured":"von Wulffen H, Hartard C, Scharein E. Seroreactivity to Campylobacter jejuni and gangliosides in patients with Guillain-Barr\u00e9 syndrome. J Infect Dis 1994;170:828-833.","journal-title":"J Infect Dis"},{"key":"e_1_3_1_30_2","first-page":"6","volume":"172","year":"1995","unstructured":"Rees JH, Gregson NA, Hughes RA. Anti-ganglioside antibodies in patients with Guillain-Barr\u00e9 syndrome and Campylobacter jejuni infection. J Inf Dis 1995;172:605-606. Letter, comment.","journal-title":"J Inf Dis"},{"key":"e_1_3_1_31_2","first-page":"8","volume":"47","year":"1990","unstructured":"Wijdicks EFM, Ropper AH. Acute relapsing Guillain-Barr\u00e9 syndrome after long asymptomatic intervals. Arch Neurol 1990;47:82-84.","journal-title":"Arch Neurol"},{"key":"e_1_3_1_32_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/115.1.1"},{"key":"e_1_3_1_33_2","first-page":"7","volume":"28","year":"1978","unstructured":"Seyal M, Ziegler DK, Couch JR. Recurrent Guillain-Barr\u00e9 syndrome following influenza vaccine. Neurology 1978;28:725-726.","journal-title":"Neurology"},{"key":"e_1_3_1_34_2","first-page":"5","volume":"62","year":"1995","unstructured":"Rees JH, Vaughan RW, Kondeatis E, Hughes RAC. HLA-class II alleles in Guillain-Barr\u00e9 syndrome and Miller Fisher syndrome and their association with preceding Campylobacter jejuni infection. J Neuroimmunol 1995;62:53-57.","journal-title":"J Neuroimmunol"},{"key":"e_1_3_1_35_2","first-page":"3","volume":"33","year":"1993","unstructured":"McKhann GM, Cornblath DR, Griffin JW, et al. Acute motor axonal neuropathy: a frequent cause of acute flaccid paralysis in China. Ann Neurol 1993;33:333-342.","journal-title":"Ann Neurol"},{"key":"e_1_3_1_36_2","first-page":"4","volume":"76","year":"1986","unstructured":"Sacks JJ, Lieb S, Baldy LM, et al. Epidemic campylobacteriosis associated with a community water supply. Am J Public Health 1986;76:424-429.","journal-title":"Am J Public Health"},{"key":"e_1_3_1_37_2","first-page":"7","volume":"36","year":"1994","unstructured":"Yuki N, Taki T, Takahashi M, et al. Molecular mimicry between GQ1b ganglioside and lipopolysaccharides of Campylobacter jejuni isolated from patients with Fisher's syndrome. Ann Neurol 1994;36:791-793.","journal-title":"Ann Neurol"},{"key":"e_1_3_1_38_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/175.1.7"},{"key":"e_1_3_1_39_2","unstructured":"Sheikh KA Deerinck TJ Griffin JW et al. Determination of the ultrastructural distribution of GM1- and asialo-GM1-like(Gal(b 1-3)GalNAc) epitopes in peripheral nerve fibers. Neurology 1997;48(suppl 3):281. Abstract."},{"key":"e_1_3_1_40_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005072-199601000-00001"},{"key":"e_1_3_1_41_2","first-page":"6","volume":"35","year":"1994","unstructured":"Wirguin I, Suturkova-Milosevic L, Della-Latta P, Fisher T, Brown RH, Jr., Latov N. Monoclonal IgM antibodies to GM1 and asialo-GM1 in chronic neuropathies cross-react with Campylobacter jejuni lipopolysaccharides. Ann Neurol 1994;35:698-703.","journal-title":"Ann Neurol"},{"key":"e_1_3_1_42_2","first-page":"2","volume":"61","year":"1996","unstructured":"Li CY, Xue P, Gao CY, Tian WQ, Liu RC, Yang C. Experimental Campylobacter jejuni infection in the chicken: an animal model of axonal Guillain-Barr\u00e9 syndrome. J Neurol Neurosurg Psychiatry 1996;61:279-284.","journal-title":"J Neurol Neurosurg Psychiatry"}],"container-title":["Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.neurology.org\/doi\/pdfdirect\/10.1212\/WNL.51.2.371","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,27]],"date-time":"2024-03-27T15:03:07Z","timestamp":1711551787000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.neurology.org\/doi\/10.1212\/WNL.51.2.371"}},"subtitle":["Molecular mimicry and host susceptibility"],"short-title":[],"issued":{"date-parts":[[1998,8]]},"references-count":41,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1998,8]]}},"alternative-id":["10.1212\/WNL.51.2.371"],"URL":"https:\/\/doi.org\/10.1212\/wnl.51.2.371","relation":{},"ISSN":["0028-3878","1526-632X"],"issn-type":[{"value":"0028-3878","type":"print"},{"value":"1526-632X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,8]]}}}