{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:24:45Z","timestamp":1763036685799},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurology"],"published-print":{"date-parts":[[1999,4]]},"DOI":"10.1212\/wnl.52.6.1191","type":"journal-article","created":{"date-parts":[[2012,5,13]],"date-time":"2012-05-13T13:39:19Z","timestamp":1336916359000},"page":"1191-1191","source":"Crossref","is-referenced-by-count":61,"title":["Lamotrigine-induced tourettism"],"prefix":"10.1212","volume":"52","author":[{"given":"Cesare T.","family":"Lombroso","sequence":"first","affiliation":[{"name":"From the Department of NeurologyChildren\u2019s Hospital, and Harvard Medical School, Boston, MA."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_1_2_2","first-page":"256","volume":"30","year":"1989","unstructured":"Jaward S, Richens A, Goodwin G, et al. Controlled trial of lamotrigine for refractory partial seizures. Epilepsia 1989;30:256\u2013263.","journal-title":"Epilepsia"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0920-1211(90)90099-H"},{"key":"e_1_3_1_4_2","first-page":"58.","volume":"32","year":"1991","unstructured":"Pisani F, Russo M, Trio R, et al. Lamotrigine in patients with refractory epilepsy : a follow-up of 33 months. Epilepsia 1991;32 (suppl 1):58. Abstract.","journal-title":"Epilepsia"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1159\/000116849"},{"key":"e_1_3_1_6_2","first-page":"113","volume":"35","year":"1993","unstructured":"Messenheimer J, Ramsey RE, Willmore LJ, et al. Lamotrigine therapy for partial seizures : a multicenter, placebo-controlled, double-blind crossover trial. Epilepsia 1993;35:113\u2013121.","journal-title":"Epilepsia"},{"key":"e_1_3_1_7_2","first-page":"152","volume":"46","year":"1993","unstructured":"Goa KL, Ross SR, Crisp P. Lamotrigine, a review of its pharmacological properties and clinical efficacy in epilepsy. Drugs 1993;46:152\u2013176.","journal-title":"Drugs"},{"key":"e_1_3_1_8_2","first-page":"200","volume":"91","year":"1995","unstructured":"Ferrie CD, Robinson RO, Knott C, et al. Lamotrigine as an add-on drug in typical absence seizures. Acta Neurol Scand 1995;91:200\u2013202.","journal-title":"Acta Neurol Scand"},{"key":"e_1_3_1_9_2","unstructured":"Leach  MJ Lees  G Riddle  DR.  Lamotrigine: mechanisms of action.   In:  Levy  RH Mattson  RH Meldrum  BS eds. Antiepileptic drugs. 4th ed. chap. 76.New York:Raven Press 1995:861\u2013869."},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199712183372504"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/00002826-198908000-00007"},{"key":"e_1_3_1_12_2","unstructured":"Lang AE Weiner WJ. In: Lang AE Weiner WJ eds. Drug-induced movement disorders ch. 12. Pasadena CA: Future Publishing 1992:359\u2013372."},{"key":"e_1_3_1_13_2","unstructured":"Miyasaki  JM Lang  AE.  Treatment of drug-induced movement disorders.   In:  Kurlan  R ed. Treatment of movement disorders ch. 11. Philadelphia:J.B. Lippincott 1995:429\u2013474."},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1059-1311(96)80038-0"},{"key":"e_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1998.tb01412.x"},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1998.tb01373.x"},{"key":"e_1_3_1_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1998.tb01413.x"},{"key":"e_1_3_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/0920-1211(92)90065-2"},{"key":"e_1_3_1_19_2","first-page":"107","volume":"5","year":"1994","unstructured":"Meldrum BS, Leach MJ. The mechanism of action of lamotrigine. Rev Contemp Pharmacol 1994;5:107\u2013114.","journal-title":"Rev Contemp Pharmacol"},{"key":"e_1_3_1_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00373920"},{"key":"e_1_3_1_21_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-199101000-00002"},{"key":"e_1_3_1_22_2","first-page":"341","volume":"58","year":"1992","unstructured":"Cohen DJ, Friedhoff AJ, Leckman JF. Tourette syndrome. Extending basic research to clinical care. Adv Neurol 1992;58:341\u2013362.","journal-title":"Adv Neurol"},{"key":"e_1_3_1_23_2","first-page":"176","volume":"8","year":"1993","unstructured":"Calderon-Gonzales R, Calderon-Sepulveda RF. Tourette syndrome : current concepts. Int Pediatr 1993;8:176\u2013186.","journal-title":"Int Pediatr"},{"key":"e_1_3_1_24_2","first-page":"33","volume":"45","year":"1989","unstructured":"Rasmussen SA, Delgado PL, Heninger GR, et al. Efficiency of serotonin reuptake blocker fluoxetine in the treatment of OCD. Arch Gen Psychiatr 1989;45:33\u201344.","journal-title":"Arch Gen Psychiatr"},{"key":"e_1_3_1_25_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1992.00530320106020"},{"key":"e_1_3_1_26_2","first-page":"371","volume":"19","year":"1996","unstructured":"Gilman MA, Sandy K. The endogenous opioid system in Gilles de la Tourette syndrome. Med Hypoth 1996;19:371\u2013378.","journal-title":"Med Hypoth"},{"key":"e_1_3_1_27_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410300105"},{"key":"e_1_3_1_28_2","first-page":"37","volume":"6","year":"1979","unstructured":"Butler IJ, Koslow SH, Seifart WE, et al. Biogenic metabolism in Tourette\u2019s syndrome. Arch Neurol 1979;6:37\u201339.","journal-title":"Arch Neurol"},{"key":"e_1_3_1_29_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410300408"},{"key":"e_1_3_1_30_2","first-page":"348","volume":"112","year":"1990","unstructured":"McGear EG, Zhu SG. Lamotrigine protects against kainate but not ibotenate lesions in the rat striatum. Neurosci Lectures 1990;112:348\u2013351.","journal-title":"Neurosci Lectures"},{"key":"e_1_3_1_31_2","first-page":"67","volume":"5","year":"1993","unstructured":"Zipp P, Boas H, Fischer PA. Lamotrigine-antiparkinsonian activity by blockade of glutamate release. J Neurol Trans 1993;5:67\u201375.","journal-title":"J Neurol Trans"}],"container-title":["Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.neurology.org\/doi\/full\/10.1212\/WNL.52.6.1191","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,27]],"date-time":"2024-03-27T10:56:06Z","timestamp":1711536966000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.neurology.org\/doi\/10.1212\/WNL.52.6.1191"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,4]]},"references-count":30,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1999,4]]}},"alternative-id":["10.1212\/WNL.52.6.1191"],"URL":"https:\/\/doi.org\/10.1212\/wnl.52.6.1191","relation":{},"ISSN":["0028-3878","1526-632X"],"issn-type":[{"value":"0028-3878","type":"print"},{"value":"1526-632X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,4]]}}}