{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T23:07:47Z","timestamp":1792624067933,"version":"4.5.0"},"reference-count":29,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurology"],"published-print":{"date-parts":[[1999,10]]},"DOI":"10.1212\/wnl.53.6.1233","type":"journal-article","created":{"date-parts":[[2012,5,13]],"date-time":"2012-05-13T13:41:46Z","timestamp":1336916506000},"page":"1233-1233","source":"Crossref","is-referenced-by-count":68,"title":["Myasthenia, thymoma, presynaptic antibodies, and a continuum of neuromuscular hyperexcitability"],"prefix":"10.1212","volume":"53","author":[{"given":"Steven","family":"Vernino","sequence":"first","affiliation":[{"name":"From the Departments of Neurology (Drs. VerninoAuger, Emslie-Smith, Harper, and Lennon), Immunology (Dr. Lennon), and Laboratory Medicine and Pathology (Dr. Lennon), Mayo Clinic and Mayo Foundation, Rochester, MN."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond G.","family":"Auger","sequence":"additional","affiliation":[{"name":"From the Departments of Neurology (Drs. VerninoAuger, Emslie-Smith, Harper, and Lennon), Immunology (Dr. Lennon), and Laboratory Medicine and Pathology (Dr. Lennon), Mayo Clinic and Mayo Foundation, Rochester, MN."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison M.","family":"Emslie-Smith","sequence":"additional","affiliation":[{"name":"From the Departments of Neurology (Drs. VerninoAuger, Emslie-Smith, Harper, and Lennon), Immunology (Dr. Lennon), and Laboratory Medicine and Pathology (Dr. Lennon), Mayo Clinic and Mayo Foundation, Rochester, MN."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. Michel","family":"Harper","sequence":"additional","affiliation":[{"name":"From the Departments of Neurology (Drs. VerninoAuger, Emslie-Smith, Harper, and Lennon), Immunology (Dr. Lennon), and Laboratory Medicine and Pathology (Dr. Lennon), Mayo Clinic and Mayo Foundation, Rochester, MN."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanda A.","family":"Lennon","sequence":"additional","affiliation":[{"name":"From the Departments of Neurology (Drs. VerninoAuger, Emslie-Smith, Harper, and Lennon), Immunology (Dr. Lennon), and Laboratory Medicine and Pathology (Dr. Lennon), Mayo Clinic and Mayo Foundation, Rochester, MN."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.26.11.1054"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199406233302507"},{"key":"e_1_3_2_4_2","first-page":"S122.","volume":"21","year":"1998","unstructured":"Griesmann GE, Harper CM, Lennon VA. Paraneoplastic myasthenia gravis and lung carcinoma: distinction from Lambert-Eaton syndrome and hypothesis of aberrant muscle acetylcholine receptor (AChR) expression. Muscle Nerve 1998;21 (suppl 7):S122. Abstract.","journal-title":"Muscle Nerve"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880171103"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.24.4.319"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/116.2.453"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4598(199703)20:3<299::AID-MUS6>3.0.CO;2-6"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410410215"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.50.6.1806"},{"key":"e_1_3_2_11_2","first-page":"448.","volume":"59","year":"1995","unstructured":"Riche G, Trouillas P, Bady B. Improvement of Isaac\u2019s syndrome after treatment with azathioprine. J Neurol Neurosurg Psychiatry 1995;59:448. Letter.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)90073-X"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.1988.tb11424.x"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1994.sp020151"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.41.7.1021"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.44.10.1915"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1989.00520400065020"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1996.00550020113023"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-6196(12)65645-6"},{"key":"e_1_3_2_20_2","unstructured":"Griesmann GE Lennon VA. Detection of autoantibodies in myasthenia gravis and Lambert-Eaton myasthenic syndrome. In: Rose NR de Macerio EC Folds JD Lane HC Nakamura RM eds. Clinical and laboratory immunology. 5th ed. Washington DC: ASM Press chapter 123 1997:983\u2013988."},{"key":"e_1_3_2_21_2","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/S0026-895X(25)10533-6","volume":"48","year":"1995","unstructured":"Gerzanich V, Peng X, Wang F, et al. Comparative pharmacology of epibatidine: a potent agonist for neuronal nicotinic acetylcholine receptors. Mol Pharmacol 1995;48:774\u2013782.","journal-title":"Mol Pharmacol"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410290218"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00314093"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1620\/tjem.164.285"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1987.tb51321.x"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.48.1.23"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.151.11.6517"},{"key":"e_1_3_2_28_2","first-page":"A121.","volume":"52","year":"1999","unstructured":"Vernino S, Auger RG, Lennon VA. Disorders of continuous muscle fiber activity: ion channel autoantibodies suggest that Isaacs syndrome is part of a pathophysiological spectrum. Neurology 1999;52:A121.","journal-title":"Neurology"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(95)11824-G"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-2236(96)10073-4"}],"container-title":["Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.neurology.org\/doi\/full\/10.1212\/WNL.53.6.1233","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,27]],"date-time":"2025-03-27T22:47:50Z","timestamp":1743115670000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.neurology.org\/doi\/10.1212\/WNL.53.6.1233"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,10]]},"references-count":29,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1999,10]]}},"alternative-id":["10.1212\/WNL.53.6.1233"],"URL":"https:\/\/doi.org\/10.1212\/wnl.53.6.1233","relation":{},"ISSN":["0028-3878","1526-632X"],"issn-type":[{"value":"0028-3878","type":"print"},{"value":"1526-632X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,10]]}}}