{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T10:47:15Z","timestamp":1792234035632,"version":"4.4.0"},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["neurology.org"],"crossmark-restriction":true},"short-container-title":["Neurology"],"published-print":{"date-parts":[[2003,1,14]]},"DOI":"10.1212\/wnl.60.1.57","type":"journal-article","created":{"date-parts":[[2012,5,13]],"date-time":"2012-05-13T14:10:41Z","timestamp":1336918241000},"page":"57-63","update-policy":"https:\/\/doi.org\/10.1212\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":94,"title":["Hereditary infantile hemiparesis, retinal arteriolar tortuosity, and leukoencephalopathy"],"prefix":"10.1212","volume":"60","author":[{"given":"K.","family":"Vahedi","sequence":"first","affiliation":[{"name":"From the Service de Neurologie (Drs. Vahedi and Bousser), Service d\u2019Ophtalmologie (Drs. Massin and Gaudric), Service de Neuroradiologie (Dr. Guichard), Service d\u2019Anatomie et Cytologie Pathologiques (Dr. Polivka), and Laboratoire de Cytoge\u0301ne\u0301tique (Dr. Tournier-Lasserve), Assistance Publique\u2013Ho\u0302pitaux de Paris, Ho\u0302pital Lariboisie\u0300re, Paris; Service d\u2019Ophtalmologie (Dr. Miocque) and Service de Neuropathologie (Dr. Chapon), Centre Hospitalier Universitaire de Caen; Unite\u0301 de Neurope\u0301diatrie (Dr...."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Massin","sequence":"additional","affiliation":[{"name":"From the Service de Neurologie (Drs. Vahedi and Bousser), Service d\u2019Ophtalmologie (Drs. Massin and Gaudric), Service de Neuroradiologie (Dr. Guichard), Service d\u2019Anatomie et Cytologie Pathologiques (Dr. Polivka), and Laboratoire de Cytoge\u0301ne\u0301tique (Dr. Tournier-Lasserve), Assistance Publique\u2013Ho\u0302pitaux de Paris, Ho\u0302pital Lariboisie\u0300re, Paris; Service d\u2019Ophtalmologie (Dr. Miocque) and Service de Neuropathologie (Dr. Chapon), Centre Hospitalier Universitaire de Caen; Unite\u0301 de Neurope\u0301diatrie (Dr...."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.-P.","family":"Guichard","sequence":"additional","affiliation":[{"name":"From the Service de Neurologie (Drs. Vahedi and Bousser), Service d\u2019Ophtalmologie (Drs. Massin and Gaudric), Service de Neuroradiologie (Dr. Guichard), Service d\u2019Anatomie et Cytologie Pathologiques (Dr. Polivka), and Laboratoire de Cytoge\u0301ne\u0301tique (Dr. Tournier-Lasserve), Assistance Publique\u2013Ho\u0302pitaux de Paris, Ho\u0302pital Lariboisie\u0300re, Paris; Service d\u2019Ophtalmologie (Dr. Miocque) and Service de Neuropathologie (Dr. Chapon), Centre Hospitalier Universitaire de Caen; Unite\u0301 de Neurope\u0301diatrie (Dr...."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Miocque","sequence":"additional","affiliation":[{"name":"From the Service de Neurologie (Drs. Vahedi and Bousser), Service d\u2019Ophtalmologie (Drs. Massin and Gaudric), Service de Neuroradiologie (Dr. Guichard), Service d\u2019Anatomie et Cytologie Pathologiques (Dr. Polivka), and Laboratoire de Cytoge\u0301ne\u0301tique (Dr. Tournier-Lasserve), Assistance Publique\u2013Ho\u0302pitaux de Paris, Ho\u0302pital Lariboisie\u0300re, Paris; Service d\u2019Ophtalmologie (Dr. Miocque) and Service de Neuropathologie (Dr. Chapon), Centre Hospitalier Universitaire de Caen; Unite\u0301 de Neurope\u0301diatrie (Dr...."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Polivka","sequence":"additional","affiliation":[{"name":"From the Service de Neurologie (Drs. Vahedi and Bousser), Service d\u2019Ophtalmologie (Drs. Massin and Gaudric), Service de Neuroradiologie (Dr. Guichard), Service d\u2019Anatomie et Cytologie Pathologiques (Dr. Polivka), and Laboratoire de Cytoge\u0301ne\u0301tique (Dr. Tournier-Lasserve), Assistance Publique\u2013Ho\u0302pitaux de Paris, Ho\u0302pital Lariboisie\u0300re, Paris; Service d\u2019Ophtalmologie (Dr. Miocque) and Service de Neuropathologie (Dr. Chapon), Centre Hospitalier Universitaire de Caen; Unite\u0301 de Neurope\u0301diatrie (Dr...."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Goutie\u0300res","sequence":"additional","affiliation":[{"name":"From the Service de Neurologie (Drs. Vahedi and Bousser), Service d\u2019Ophtalmologie (Drs. Massin and Gaudric), Service de Neuroradiologie (Dr. Guichard), Service d\u2019Anatomie et Cytologie Pathologiques (Dr. Polivka), and Laboratoire de Cytoge\u0301ne\u0301tique (Dr. Tournier-Lasserve), Assistance Publique\u2013Ho\u0302pitaux de Paris, Ho\u0302pital Lariboisie\u0300re, Paris; Service d\u2019Ophtalmologie (Dr. Miocque) and Service de Neuropathologie (Dr. Chapon), Centre Hospitalier Universitaire de Caen; Unite\u0301 de Neurope\u0301diatrie (Dr...."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Dress","sequence":"additional","affiliation":[{"name":"From the Service de Neurologie (Drs. Vahedi and Bousser), Service d\u2019Ophtalmologie (Drs. Massin and Gaudric), Service de Neuroradiologie (Dr. Guichard), Service d\u2019Anatomie et Cytologie Pathologiques (Dr. Polivka), and Laboratoire de Cytoge\u0301ne\u0301tique (Dr. Tournier-Lasserve), Assistance Publique\u2013Ho\u0302pitaux de Paris, Ho\u0302pital Lariboisie\u0300re, Paris; Service d\u2019Ophtalmologie (Dr. Miocque) and Service de Neuropathologie (Dr. Chapon), Centre Hospitalier Universitaire de Caen; Unite\u0301 de Neurope\u0301diatrie (Dr...."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Chapon","sequence":"additional","affiliation":[{"name":"From the Service de Neurologie (Drs. Vahedi and Bousser), Service d\u2019Ophtalmologie (Drs. Massin and Gaudric), Service de Neuroradiologie (Dr. Guichard), Service d\u2019Anatomie et Cytologie Pathologiques (Dr. Polivka), and Laboratoire de Cytoge\u0301ne\u0301tique (Dr. Tournier-Lasserve), Assistance Publique\u2013Ho\u0302pitaux de Paris, Ho\u0302pital Lariboisie\u0300re, Paris; Service d\u2019Ophtalmologie (Dr. Miocque) and Service de Neuropathologie (Dr. Chapon), Centre Hospitalier Universitaire de Caen; Unite\u0301 de Neurope\u0301diatrie (Dr...."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.-M.","family":"Ruchoux","sequence":"additional","affiliation":[{"name":"From the Service de Neurologie (Drs. Vahedi and Bousser), Service d\u2019Ophtalmologie (Drs. Massin and Gaudric), Service de Neuroradiologie (Dr. Guichard), Service d\u2019Anatomie et Cytologie Pathologiques (Dr. Polivka), and Laboratoire de Cytoge\u0301ne\u0301tique (Dr. Tournier-Lasserve), Assistance Publique\u2013Ho\u0302pitaux de Paris, Ho\u0302pital Lariboisie\u0300re, Paris; Service d\u2019Ophtalmologie (Dr. Miocque) and Service de Neuropathologie (Dr. Chapon), Centre Hospitalier Universitaire de Caen; Unite\u0301 de Neurope\u0301diatrie (Dr...."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Riant","sequence":"additional","affiliation":[{"name":"From the Service de Neurologie (Drs. Vahedi and Bousser), Service d\u2019Ophtalmologie (Drs. Massin and Gaudric), Service de Neuroradiologie (Dr. Guichard), Service d\u2019Anatomie et Cytologie Pathologiques (Dr. Polivka), and Laboratoire de Cytoge\u0301ne\u0301tique (Dr. Tournier-Lasserve), Assistance Publique\u2013Ho\u0302pitaux de Paris, Ho\u0302pital Lariboisie\u0300re, Paris; Service d\u2019Ophtalmologie (Dr. Miocque) and Service de Neuropathologie (Dr. Chapon), Centre Hospitalier Universitaire de Caen; Unite\u0301 de Neurope\u0301diatrie (Dr...."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Joutel","sequence":"additional","affiliation":[{"name":"From the Service de Neurologie (Drs. Vahedi and Bousser), Service d\u2019Ophtalmologie (Drs. Massin and Gaudric), Service de Neuroradiologie (Dr. Guichard), Service d\u2019Anatomie et Cytologie Pathologiques (Dr. Polivka), and Laboratoire de Cytoge\u0301ne\u0301tique (Dr. Tournier-Lasserve), Assistance Publique\u2013Ho\u0302pitaux de Paris, Ho\u0302pital Lariboisie\u0300re, Paris; Service d\u2019Ophtalmologie (Dr. Miocque) and Service de Neuropathologie (Dr. Chapon), Centre Hospitalier Universitaire de Caen; Unite\u0301 de Neurope\u0301diatrie (Dr...."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Gaudric","sequence":"additional","affiliation":[{"name":"From the Service de Neurologie (Drs. Vahedi and Bousser), Service d\u2019Ophtalmologie (Drs. Massin and Gaudric), Service de Neuroradiologie (Dr. Guichard), Service d\u2019Anatomie et Cytologie Pathologiques (Dr. Polivka), and Laboratoire de Cytoge\u0301ne\u0301tique (Dr. Tournier-Lasserve), Assistance Publique\u2013Ho\u0302pitaux de Paris, Ho\u0302pital Lariboisie\u0300re, Paris; Service d\u2019Ophtalmologie (Dr. Miocque) and Service de Neuropathologie (Dr. Chapon), Centre Hospitalier Universitaire de Caen; Unite\u0301 de Neurope\u0301diatrie (Dr...."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.-G.","family":"Bousser","sequence":"additional","affiliation":[{"name":"From the Service de Neurologie (Drs. Vahedi and Bousser), Service d\u2019Ophtalmologie (Drs. Massin and Gaudric), Service de Neuroradiologie (Dr. Guichard), Service d\u2019Anatomie et Cytologie Pathologiques (Dr. Polivka), and Laboratoire de Cytoge\u0301ne\u0301tique (Dr. Tournier-Lasserve), Assistance Publique\u2013Ho\u0302pitaux de Paris, Ho\u0302pital Lariboisie\u0300re, Paris; Service d\u2019Ophtalmologie (Dr. Miocque) and Service de Neuropathologie (Dr. Chapon), Centre Hospitalier Universitaire de Caen; Unite\u0301 de Neurope\u0301diatrie (Dr...."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Tournier-Lasserve","sequence":"additional","affiliation":[{"name":"From the Service de Neurologie (Drs. Vahedi and Bousser), Service d\u2019Ophtalmologie (Drs. Massin and Gaudric), Service de Neuroradiologie (Dr. Guichard), Service d\u2019Anatomie et Cytologie Pathologiques (Dr. Polivka), and Laboratoire de Cytoge\u0301ne\u0301tique (Dr. Tournier-Lasserve), Assistance Publique\u2013Ho\u0302pitaux de Paris, Ho\u0302pital Lariboisie\u0300re, Paris; Service d\u2019Ophtalmologie (Dr. Miocque) and Service de Neuropathologie (Dr. Chapon), Centre Hospitalier Universitaire de Caen; Unite\u0301 de Neurope\u0301diatrie (Dr...."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(88)33131-3"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320340217"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.53.3.629"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.49.5.1322"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1177\/112067219100100204"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/121.2.303"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1086\/321975"},{"key":"e_1_3_2_9_2","first-page":"532","volume":"132","year":"1958","unstructured":"Beyer EM. Famili\u00e4re tortuositas der kleinen netzhautarterien mit makulablutung. Klin Monatsbl Augenheilkd . 1958; 132: 532\u2013539.","journal-title":"Klin Monatsbl Augenheilkd"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(72)90131-6"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(72)90541-7"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(83)90282-9"},{"key":"e_1_3_2_13_2","first-page":"42","volume":"15","year":"1983","unstructured":"Kayazawa F, Machida T. Retinal arteriolar tortuosity with macular hemorrhage. Ann Ophthalmol . 1983; 15: 42\u201343.","journal-title":"Ann Ophthalmol"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(85)33905-2"},{"key":"e_1_3_2_15_2","first-page":"568","volume":"105","year":"1986","unstructured":"Clearkin LG, Rose H, Patterson A, Mody CH. Development of retinal arteriolar tortuosity in previously unaffected family members. Trans Ophthalmol Soc UK . 1986; 105: 568\u2013574.","journal-title":"Trans Ophthalmol Soc UK"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.116.9.1185"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)08083-5"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng0393-256"},{"key":"e_1_3_2_19_2","first-page":"266.","volume":"3","year":"1984","unstructured":"Poirier J, Derouesne C. Cerebral lacunae. A proposed new classification. Clin Neuropathol . 1984; 3: 266.","journal-title":"Clin Neuropathol"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/114.2.761"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(95)91557-5"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00571504"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6257(00)00206-X"}],"container-title":["Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.neurology.org\/doi\/pdfdirect\/10.1212\/WNL.60.1.57","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,28]],"date-time":"2024-03-28T15:32:52Z","timestamp":1711639972000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.neurology.org\/doi\/10.1212\/WNL.60.1.57"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,1,14]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2003,1,14]]}},"alternative-id":["10.1212\/WNL.60.1.57"],"URL":"https:\/\/doi.org\/10.1212\/wnl.60.1.57","relation":{},"ISSN":["0028-3878","1526-632X"],"issn-type":[{"value":"0028-3878","type":"print"},{"value":"1526-632X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,1,14]]}}}