{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T01:22:13Z","timestamp":1774056133491,"version":"3.50.1"},"reference-count":38,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","content-domain":{"domain":["neurology.org"],"crossmark-restriction":true},"short-container-title":["Neurology"],"published-print":{"date-parts":[[2008,9,2]]},"DOI":"10.1212\/01.wnl.0000324919.86696.a9","type":"journal-article","created":{"date-parts":[[2008,9,2]],"date-time":"2008-09-02T12:21:03Z","timestamp":1220358063000},"page":"723-730","update-policy":"https:\/\/doi.org\/10.1212\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":103,"title":["Antiepileptic drug use and rates of hip bone loss in older men"],"prefix":"10.1212","volume":"71","author":[{"given":"K. E.","family":"Ensrud","sequence":"first","affiliation":[{"name":"From the Center for Chronic Disease Outcomes Research (K.E.E.), VA Medical Center, Minneapolis; Department of Medicine and Division of Epidemiology & Community Health (K.E.E.) and Department of Neurology (T.S.W.), University of Minnesota, Minneapolis; Minnesota Comprehensive Epilepsy Program (T.S.W.), Minneapolis; Research Institute (T.L.B.), California Pacific Medical Center, San Francisco; Department of Neurology (E.R.E.), VA Medical Center, Boston, MA; Department of Family & Preventive..."}]},{"given":"T. S.","family":"Walczak","sequence":"additional","affiliation":[{"name":"From the Center for Chronic Disease Outcomes Research (K.E.E.), VA Medical Center, Minneapolis; Department of Medicine and Division of Epidemiology & Community Health (K.E.E.) and Department of Neurology (T.S.W.), University of Minnesota, Minneapolis; Minnesota Comprehensive Epilepsy Program (T.S.W.), Minneapolis; Research Institute (T.L.B.), California Pacific Medical Center, San Francisco; Department of Neurology (E.R.E.), VA Medical Center, Boston, MA; Department of Family & Preventive..."}]},{"given":"T. L.","family":"Blackwell","sequence":"additional","affiliation":[{"name":"From the Center for Chronic Disease Outcomes Research (K.E.E.), VA Medical Center, Minneapolis; Department of Medicine and Division of Epidemiology & Community Health (K.E.E.) and Department of Neurology (T.S.W.), University of Minnesota, Minneapolis; Minnesota Comprehensive Epilepsy Program (T.S.W.), Minneapolis; Research Institute (T.L.B.), California Pacific Medical Center, San Francisco; Department of Neurology (E.R.E.), VA Medical Center, Boston, MA; Department of Family & Preventive..."}]},{"given":"E. R.","family":"Ensrud","sequence":"additional","affiliation":[{"name":"From the Center for Chronic Disease Outcomes Research (K.E.E.), VA Medical Center, Minneapolis; Department of Medicine and Division of Epidemiology & Community Health (K.E.E.) and Department of Neurology (T.S.W.), University of Minnesota, Minneapolis; Minnesota Comprehensive Epilepsy Program (T.S.W.), Minneapolis; Research Institute (T.L.B.), California Pacific Medical Center, San Francisco; Department of Neurology (E.R.E.), VA Medical Center, Boston, MA; Department of Family & Preventive..."}]},{"given":"E.","family":"Barrett-Connor","sequence":"additional","affiliation":[{"name":"From the Center for Chronic Disease Outcomes Research (K.E.E.), VA Medical Center, Minneapolis; Department of Medicine and Division of Epidemiology & Community Health (K.E.E.) and Department of Neurology (T.S.W.), University of Minnesota, Minneapolis; Minnesota Comprehensive Epilepsy Program (T.S.W.), Minneapolis; Research Institute (T.L.B.), California Pacific Medical Center, San Francisco; Department of Neurology (E.R.E.), VA Medical Center, Boston, MA; Department of Family & Preventive..."}]},{"given":"E. S.","family":"Orwoll","sequence":"additional","affiliation":[{"name":"From the Center for Chronic Disease Outcomes Research (K.E.E.), VA Medical Center, Minneapolis; Department of Medicine and Division of Epidemiology & Community Health (K.E.E.) and Department of Neurology (T.S.W.), University of Minnesota, Minneapolis; Minnesota Comprehensive Epilepsy Program (T.S.W.), Minneapolis; Research Institute (T.L.B.), California Pacific Medical Center, San Francisco; Department of Neurology (E.R.E.), VA Medical Center, Boston, MA; Department of Family & Preventive..."}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-006-0185-z"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s001980070062"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.57.3.445"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0387-7604(94)90125-2"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0920-1211(98)00077-1"},{"key":"e_1_3_2_7_2","first-page":"631","year":"1994","unstructured":"Valimaki MJ, Tiihonen M, Laitinen K, et al. Bone mineral density measured by dual-energy x-ray absorptiometry and novel markers of bone formation and resorption in patients on antiepileptic drugs. J Bone Miner Res 1994;9:631\u2013637.","journal-title":"J Bone Miner Res"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.20378"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(95)70304-7"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1177\/000992289903800205"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2006.11.007"},{"key":"e_1_3_2_12_2","first-page":"S3","volume":"5","year":"2004","unstructured":"Fitzpatrick LA. Pathophysiology of bone loss in patients receiving anticonvulsant therapy. Epilepsy Behav 2004;5 suppl 2:S3\u201315.","journal-title":"Epilepsy Behav"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.291.5.615"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(04)00935-4"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2003.11.029"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cct.2005.05.006"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cct.2005.05.005"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01719664"},{"key":"e_1_3_2_19_2","first-page":"336","volume":"39","year":"1999","unstructured":"Washburn RA, Ficker JL. Physical Activity Scale for the Elderly (PASE): the relationship with activity measured by a portable accelerometer. J Sports Med Phys Fitness 1999;39:336\u2013340.","journal-title":"J Sports Med Phys Fitness"},{"key":"e_1_3_2_20_2","first-page":"969","year":"1992","unstructured":"Block G, Subar AF. Estimates of nutrient intake from a food frequency questionnaire: the 1987 National Health Interview Survey. J Am Diet Assoc 1992;92:969\u2013977.","journal-title":"J Am Diet Assoc"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-127-8_Part_2-199710151-00064"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.59.5.781"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000125185.74276.D2"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0013-9580.2004.18804.x"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000210503.89488.88"},{"key":"e_1_3_2_26_2","first-page":"37","volume":"108","year":"2000","unstructured":"Feldkamp J, Becker A, Witte OW, Scharff D, Scherbaum WA. Long-term anticonvulsant therapy leads to low bone mineral density: evidence for direct drug effects of phenytoin and carbamazepine on human osteoblast-like cells. Exp Clin Endocrinol Diabetes 2000;108:37\u201343.","journal-title":"Exp Clin Endocrinol Diabetes"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.20544"},{"key":"e_1_3_2_28_2","first-page":"S440Abs","volume":"19","year":"2004","unstructured":"Gracious BL, Bossert RP, Puza J. Valproic acid inhibits osteoblast and osteoclast activity in therapeutic dose ranges. J Bone Miner Res 2004;19(suppl 1):S440Abs.","journal-title":"J Bone Miner Res"},{"key":"e_1_3_2_29_2","first-page":"2254","year":"2005","unstructured":"Schroeder TM, Westendorf JJ. Histone deacetylase inhibitors promote osteoblast maturation. J Bone Miner Res 2005;20:2254\u20132263.","journal-title":"J Bone Miner Res"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2007.01176.x"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200703000-00021"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(02)01049-8"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1972.tb05167.x"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2006.10.001"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1528-1157.2001.042002292.x"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1990.00530060082023"},{"key":"e_1_3_2_37_2","first-page":"339","year":"1981","unstructured":"Kruse K, Kracht U. Inhibitory effect of calcium on serum prolactin. Acta Endocrinol (Copenh) 1981;98:339\u2013344.","journal-title":"Acta Endocrinol (Copenh)"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0013-9580.2005.23804.x"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.2005.00474.x"}],"container-title":["Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.neurology.org\/doi\/pdfdirect\/10.1212\/01.wnl.0000324919.86696.a9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,28]],"date-time":"2024-03-28T10:29:34Z","timestamp":1711621774000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.neurology.org\/doi\/10.1212\/01.wnl.0000324919.86696.a9"}},"subtitle":["A prospective study"],"short-title":[],"issued":{"date-parts":[[2008,9,2]]},"references-count":38,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2008,9,2]]}},"alternative-id":["10.1212\/01.wnl.0000324919.86696.a9"],"URL":"https:\/\/doi.org\/10.1212\/01.wnl.0000324919.86696.a9","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.1123447.580619","asserted-by":"object"}]},"ISSN":["0028-3878","1526-632X"],"issn-type":[{"value":"0028-3878","type":"print"},{"value":"1526-632X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,9,2]]}}}