{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T06:12:59Z","timestamp":1789020779437,"version":"build-2803163510"},"reference-count":29,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","license":[{"start":{"date-parts":[[2024,12,23]],"date-time":"2024-12-23T00:00:00Z","timestamp":1734912000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>This study examined the association between opioid-use disorder (OUD)-related diagnoses (eg, opioid dependence) and social determinants of health (SDoH) among patients with chronic pain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>A cross-sectional study was performed using the All of Us dataset (including &gt;70,000 patients) to measure associations between SDoH and OUD using population- and individual-level surveys. Mixed-effects multivariable regression models (random effect being zip code) were conducted for each of the key SDoH domains. The odds ratio (OR) and 95% confidence interval (CI) were reported.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      There were 71,727 participants identified to have chronic pain, of which 7272 (10.1%) had OUD. Using data from all participants with population-level survey data available (n = 71,684), the Area Deprivation Index was associated with increased odds of OUD (OR, 5.70, 95% CI, 2.34\u201313.83,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001). Being unemployed (OR, 1.91, 95% CI, 1.59\u20132.31,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001) was associated with OUD. Chronic pain patients with a college degree or greater had lower odds of having OUD (OR, 0.48, 95% CI, 0.39\u20130.59,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001). Responses to questions related to delayed medical care (OR, 1.42, 95% CI, 1.20\u20131.69,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001) and inability to afford medical care (OR, 1.37, 95% CI, 1.16\u20131.63,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001) were associated with an increased odds of OUD. Chronic pain patients who were never married or without a partner (OR, 1.49, 95% CI, 1.28\u20131.73,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001) had higher odds of OUD.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>The study revealed a significantly greater social disadvantage metric in chronic pain individuals with OUD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1213\/ane.0000000000007247","type":"journal-article","created":{"date-parts":[[2024,12,23]],"date-time":"2024-12-23T13:00:28Z","timestamp":1734958828000},"page":"1149-1158","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":10,"title":["Associations Between Social Determinants of Health and Opioid-Use Disorder Among Chronic Pain Patients From a Multi-Institutional Dataset"],"prefix":"10.1213","volume":"141","author":[{"given":"Veena M.","family":"Do","sequence":"first","affiliation":[{"name":"School of Medicine, University of California San Diego, San Diego, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sierra","family":"Simpson","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Division of Perioperative Informatics, University of California San Diego, La Jolla, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen M.","family":"Fisch","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Diego, La Jolla, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodney A.","family":"Gabriel","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Division of Perioperative Informatics, University of California San Diego, La Jolla, California"},{"name":"Department of Biomedical Informatics, University of California San Diego, La Jolla, California."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,12,23]]},"reference":[{"key":"R2-20251020","doi-asserted-by":"crossref","first-page":"e15425","DOI":"10.1097\/MD.0000000000015425","article-title":"Current perspectives on the opioid crisis in the US healthcare system: A comprehensive literature review.","volume":"98","author":"Stoicea","year":"2019","journal-title":"Medicine (Baltim)"},{"key":"R3-20251020","year":"2020"},{"key":"R4-20251020","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1037\/a0022025","article-title":"Socioeconomic disparities in pain: the role of economic hardship and daily financial worry.","volume":"30","author":"Rios","year":"2011","journal-title":"Health Psychol"},{"key":"R6-20251020","first-page":"692","article-title":"The perceived control over pain construct and functional 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A general population study.","volume":"23","author":"Lacey","year":"2013","journal-title":"Eur J Public Health"},{"key":"R18-20251020","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1097\/00002508-200209000-00003","article-title":"Educational achievement and chronic pain disability: mediating role of pain-related cognitions.","volume":"18","author":"Roth","year":"2002","journal-title":"Clin J Pain"},{"key":"R19-20251020","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/S0022-3999(01)00242-2","article-title":"Educational achievement and pain disability among women with chronic pelvic pain.","volume":"51","author":"Roth","year":"2001","journal-title":"J Psychosom Res"},{"key":"R20-20251020","doi-asserted-by":"crossref","first-page":"573","DOI":"10.7326\/0003-4819-147-8-200710160-00010","article-title":"The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: guidelines for reporting observational studies.","volume":"147","author":"von Elm","year":"2007","journal-title":"Ann Intern Med"},{"key":"R23-20251020","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1056\/NEJMsr1809937","article-title":"The \u201cAll of Us\u201d research program.","volume":"381","year":"2019","journal-title":"N Engl J Med"},{"key":"R27-20251020","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.jsat.2017.03.006","article-title":"Chronic pain among patients with opioid use disorder: results from electronic health records data.","volume":"77","author":"Hser","year":"2017","journal-title":"J Subst Abuse Treat"},{"key":"R28-20251020","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1002\/ejp.2163","article-title":"Socioeconomic risk factors for long-term opioid use: a national registry-linkage study.","volume":"28","author":"Nestvold","year":"2024","journal-title":"Eur J Pain"},{"key":"R29-20251020","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1093\/pm\/pny169","article-title":"Relationship between opioid analgesic prescription and unemployment in patients seeking acupuncture for chronic pain in Urban primary care.","volume":"20","author":"Chuang","year":"2019","journal-title":"Pain Med"},{"key":"R31-20251020","article-title":"Improving access to evidence-based medical treatment for opioid use disorder: Strategies to address key barriers within the treatment system.","volume":"2020","author":"Madras","year":"2020","journal-title":"NAM Perspect"},{"key":"R32-20251020","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.drugalcdep.2018.11.024","article-title":"Urban-rural variation in the socioeconomic determinants of opioid overdose.","volume":"195","author":"Pear","year":"2019","journal-title":"Drug Alcohol Depend"},{"key":"R34-20251020","doi-asserted-by":"crossref","first-page":"107618","DOI":"10.1016\/j.drugalcdep.2019.107618","article-title":"The impact of opioid use disorder on levels of educational attainment: Perceived benefits and consequences.","volume":"206","author":"Ellis","year":"2020","journal-title":"Drug Alcohol Depend"},{"key":"R37-20251020","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1016\/j.jpain.2018.04.004","article-title":"Prescription medication use among community-based U.S. adults with chronic low back pain: a cross-sectional population based study.","volume":"19","author":"Shmagel","year":"2018","journal-title":"J Pain"},{"key":"R38-20251020","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1089\/acm.2016.29016.jjw","article-title":"Influential U.S. medical organizations call for insurance coverage of non-pharmacologic approaches to pain.","volume":"22","author":"Weeks","year":"2016","journal-title":"J Altern Complement Med"},{"key":"R39-20251020","doi-asserted-by":"crossref","first-page":"108367","DOI":"10.1016\/j.jsat.2021.108367","article-title":"The role of social network support in treatment outcomes for medication for opioid use disorder: a systematic review.","volume":"127","author":"Kumar","year":"2021","journal-title":"J Subst Abuse Treat"},{"key":"R40-20251020","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1037\/0022-006X.71.3.432","article-title":"Behavioral family counseling and naltrexone for male opioid-dependent patients.","volume":"71","author":"Fals-Stewart","year":"2003","journal-title":"J Consult Clin Psychol"}],"container-title":["Anesthesia &amp; 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