{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T17:23:11Z","timestamp":1786123391814,"version":"build-2736575974"},"reference-count":50,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>Sepsis disproportionately affects marginalized communities. This study aims to evaluate racial and ethnic disparities in failure-to-rescue (FTR) after postoperative sepsis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>This cross-sectional study used data from the American College of Surgeons National Surgical Quality Improvement Program for patients who underwent inpatient noncardiac surgery between 2018 and 2021. Patients were categorized as non-Hispanic White (hereafter, White), non-Hispanic Black (hereafter, Black), Asian, and Hispanic individuals. The association between (1) FTR after sepsis and (2) FTR after septic shock and race and ethnicity was evaluated using multivariable logistic regression. Failure-to-rescue was defined as 30-day mortality among patients who developed postoperative sepsis or postoperative septic shock.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      Among the 1388,977 patients (mean [SD] age 60.5 [16]); 783,056 (56.4%) were female, 1017,875 (73%) were White, 171,774 (12%) were Black, 138,457 (10%) were Hispanic, and 60,871 (4%) were Asian. Compared to White individuals, Black (adjusted odds ratio [aOR], 1.29; 95% CI, 1.23\u20131.35,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001) and Hispanic individuals (aOR, 1.15; 95% CI, 1.09\u20131.21,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001) were more likely to develop sepsis; Black individuals were more likely to develop septic shock (aOR, 1.28; 95% CI, 1.21\u20131.36;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001), and Asians were less likely to develop septic shock (aOR 0.84; 95% CI, 0.75\u20130.93,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .002). Black individuals experienced lower rates of FTR after sepsis [Black: (aOR, 0.71; 95% CI, 0.54\u20140.94;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .017), while Black (aOR, 0.93; 95% CI, 0.80\u20131.08;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .35)], Hispanic (aOR, 0.87; 95% CI, 0.72\u20131.06;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .16) and Asian Individuals (aOR, 1.06; 95% CI, 0.8\u20131.37;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .67) experienced similar rates of FTR after septic shock compared to White individuals.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>Black and Hispanic individuals experienced higher rates of postoperative sepsis but did not experience higher rates of failure-to-rescue. Reducing inequity in surgical care should focus on efforts to prevent postoperative sepsis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1213\/ane.0000000000007303","type":"journal-article","created":{"date-parts":[[2024,12,2]],"date-time":"2024-12-02T13:00:28Z","timestamp":1733144428000},"page":"181-189","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["Racial and Ethnic Disparities in Failure-to-Rescue After Postoperative Sepsis After Noncardiac Surgery"],"prefix":"10.1213","volume":"141","author":[{"given":"Andres","family":"Laserna","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, Perioperative, and Pain Medicine, Stanford University School of Medicine, Stanford, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edwin","family":"van Wijngaarden","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences, University of Rochester School of Medicine, Rochester, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric C.","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Perioperative, and Pain Medicine, Stanford University School of Medicine, Stanford, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences, University of Rochester School of Medicine, Rochester, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph L.","family":"Nates","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Division of Anesthesiology, Critical Care, and Pain Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent G.","family":"Glance","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences, University of Rochester School of Medicine, Rochester, New York"},{"name":"Department of Anesthesiology and Perioperative Medicine, University of Rochester Medical Center, Rochester, New York"},{"name":"RAND Health, RAND, Boston, Massachusetts."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,6,16]]},"reference":[{"key":"R1-20250616","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1001\/jama.2016.0287","article-title":"The third international consensus definitions for sepsis and septic shock (sepsis-3).","volume":"315","author":"Singer","year":"2016","journal-title":"JAMA"},{"key":"R2-20250616","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/S0140-6736(19)32989-7","article-title":"Global, regional, and national sepsis incidence and mortality, 1990-2017: analysis for the Global Burden of 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