{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,13]],"date-time":"2026-11-13T06:11:42Z","timestamp":1794550302019,"version":"4.9.1"},"reference-count":40,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,10]]},"abstract":"\n BACKGROUND:<\/jats:title>\n Complications occur in a third of patients after major noncardiac surgery and are often preceded by vital sign deviations undetected by current vital sign monitoring practice, despite major advances in surgical and perioperative care. Continuous wireless vital sign monitoring with real-time alerts may allow for a reduction of vital sign abnormalities and complications.<\/jats:p>\n <\/jats:sec>\n \n METHODS:<\/jats:title>\n Adult patients undergoing major noncardiac surgery were included and randomized to either standard of care (manual intermittent vital sign monitoring) vs standard of care plus continuous wireless vital sign monitoring with real-time vital sign alerts to staff smartphones at the general postoperative ward. The primary outcome was cumulative duration of severe vital sign deviations, including desaturation, tachy- and bradycardia, tachy- and bradypnea, hypo- and hypertension. Secondary outcomes included adverse events within 30 days. Patients and outcome assessors were blinded to the randomization.<\/jats:p>\n <\/jats:sec>\n \n RESULTS:<\/jats:title>\n \n Four hundred patients were randomized, with 200 in the intervention and 200 in the control group, respectively. Median [interquartile range (IQR)] duration of severely deviating vital signs was 60 [25\u2013136] vs 76 [28\u2013192] min\/d in the intervention versus control group, respectively (\n P<\/jats:italic>\n = .19). Duration of Sp\n o<\/jats:sc>\n 2<\/jats:sub>\n <88% had a mean reduction of 47 minutes per day (95% confidence interval [CI], 18\u201380,\n P<\/jats:italic>\n = .02). Adverse events occurred in 42.5% vs 31.5% of patients within 30 days (\n P<\/jats:italic>\n = .02), and serious adverse events in 34.5% vs 29.5% (\n P<\/jats:italic>\n = .39).\n <\/jats:p>\n <\/jats:sec>\n \n CONCLUSIONS:<\/jats:title>\n Continuous vital sign monitoring with real-time staff alerts did not significantly reduce cumulative severe vital sign deviations in this setup. Significant reductions in desaturations and adverse events were found, giving evidence to future studies in the use of continuous vital sign monitoring to improve patient outcomes.<\/jats:p>\n <\/jats:sec>","DOI":"10.1213\/ane.0000000000007606","type":"journal-article","created":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T13:00:40Z","timestamp":1751374840000},"page":"807-817","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":26,"title":["Continuous Vital Sign Monitoring at the Surgical Ward for Improved Outcomes After Major Noncardiac Surgery: A Randomized Clinical Trial"],"prefix":"10.1213","volume":"141","author":[{"given":"Jesper","family":"M\u00f8lgaard","sequence":"first","affiliation":[{"name":"From theDepartment of Anesthesia, Centre for Cancer and Organ Dysfunction, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katja K.","family":"Gr\u00f8nb\u00e6k","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Intensive Care, Copenhagen University Hospital \u2013 Bispebjerg and Frederiksberg, Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00f8ren S.","family":"Rasmussen","sequence":"additional","affiliation":[{"name":"Biomedical Signal Processing & AI Research Group, Digital Health Section, Department of Health Technology, Technical University of Denmark, Kgs. Lyngby, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonas P.","family":"Eiberg","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark"},{"name":"Copenhagen Academy for Medical Education and Simulation (CAMES), Centre for Human Resources and Education, Copenhagen, Denmark"},{"name":"Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars N.","family":"J\u00f8rgensen","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark"},{"name":"Digestive Disease Centre, Copenhagen University Hospital \u2013 Bispebjerg and Frederiksberg Hospitals, Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael P.","family":"Achiam","sequence":"additional","affiliation":[{"name":"Department 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