{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T14:20:38Z","timestamp":1788013238372,"version":"build-2784847793"},"reference-count":60,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,6]]},"DOI":"10.1213\/ane.0b013e3181a0b6c6","type":"journal-article","created":{"date-parts":[[2009,5,21]],"date-time":"2009-05-21T17:56:14Z","timestamp":1242928574000},"page":"1760-1768","source":"Crossref","is-referenced-by-count":108,"title":["Transfusion Management of Trauma Patients"],"prefix":"10.1213","volume":"108","author":[{"given":"Beth H.","family":"Shaz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher J.","family":"Dente","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert S.","family":"Harris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jana B.","family":"MacLeod","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher D.","family":"Hillyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-9-20210902","article-title":"The injury chart book: a graphical overview of the global burden of injuries.","author":"Peden","year":"2002"},{"key":"R2-9-20210902","article-title":"Injury: a leading cause of the global burden of disease, 2000.","author":"Peden","year":"2002"},{"key":"R4-9-20210902","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1001\/archsurg.1993.01420170107016","article-title":"The epidemiology of traumatic death. A population-based analysis.","volume":"128","author":"Shackford","year":"1993","journal-title":"Arch Surg"},{"key":"R5-9-20210902","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1136\/ip.7.2.104","article-title":"Epidemiology of violent deaths in the world.","volume":"7","author":"Reza","year":"2001","journal-title":"Inj Prev"},{"key":"R6-9-20210902","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/S1072-7515(98)00209-9","article-title":"Epidemiology of major trauma and trauma deaths in Los Angeles County.","volume":"187","author":"Demetriades","year":"1998","journal-title":"J Am Coll Surg"},{"key":"R7-9-20210902","first-page":"S3","article-title":"Impact of hemorrhage on trauma outcome: an overview of epidemiology, clinical presentations, and therapeutic considerations.","volume":"60","author":"Kauvar","year":"2006","journal-title":"J Trauma"},{"key":"R7A-9-20210902","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1097\/00005373-199502000-00006","article-title":"Epidemiology of trauma deaths: a reassessment.","volume":"38","author":"Sauaia","year":"1995","journal-title":"J Trauma"},{"key":"R8-9-20210902","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1097\/00005373-199705000-00016","article-title":"Predicting life-threatening coagulopathy in the massively transfused trauma patient: hypothermia and acidoses revisited.","volume":"42","author":"Cosgriff","year":"1997","journal-title":"J Trauma"},{"key":"R9-9-20210902","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1097\/00003246-198505000-00003","article-title":"Coagulopathy related to dilution and hypotension during massive transfusion.","volume":"13","author":"Hewson","year":"1985","journal-title":"Crit Care Med"},{"key":"R10-9-20210902","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1097\/00005373-199304000-00002","article-title":"Blood component supplementation during massive transfusion of AS-1 red cells in trauma patients.","volume":"34","author":"Faringer","year":"1993","journal-title":"J Trauma"},{"key":"R11-9-20210902","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/S0002-9610(05)81018-9","article-title":"Hypothermia and acidosis worsen coagulopathy in the patient requiring massive transfusion.","volume":"160","author":"Ferrara","year":"1990","journal-title":"Am J Surg"},{"key":"R12-9-20210902","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1111\/j.1537-2995.2004.03409.x","article-title":"Blood transfusion rates in the care of acute trauma.","volume":"44","author":"Como","year":"2004","journal-title":"Transfusion"},{"key":"R13-9-20210902","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1097\/00005373-200208000-00017","article-title":"Massive transfusion exceeding 50 units of blood products in trauma patients.","volume":"53","author":"Vaslef","year":"2002","journal-title":"J Trauma"},{"key":"R14-9-20210902","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1097\/SLA.0b013e318185a9ad","article-title":"Increased plasma and platelet to red blood cell ratios improves outcome in 466 massively transfused civilian trauma patients.","volume":"248","author":"Holcomb","year":"2008","journal-title":"Ann Surg"},{"key":"R15-9-20210902","first-page":"261","article-title":"Postinjury life threatening coagulopathy: is 1:1 fresh frozen plasma:packed red blood cells the answer?","volume":"65","author":"Kashuk","year":"2008","journal-title":"J Trauma"},{"key":"R16-9-20210902","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.jen.2005.03.004","article-title":"Variables predicting trauma patient survival following massive transfusion.","volume":"31","author":"Criddle","year":"2005","journal-title":"J Emerg Nurs"},{"key":"R17-9-20210902","article-title":"Handbook of pediatric transfusion medicine.","year":"2004"},{"key":"R18-9-20210902","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1097\/00000658-197208000-00021","article-title":"Coagulopathy after major combat injury: occurrence, management, and pathophysiology.","volume":"176","author":"McNamara","year":"1972","journal-title":"Ann Surg"},{"key":"R19-9-20210902","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/S0039-6109(05)70099-2","article-title":"Hypothermia, coagulopathy, and acidosis.","volume":"80","author":"Eddy","year":"2000","journal-title":"Surg Clin North Am"},{"key":"R20-9-20210902","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1097\/MCC.0b013e3282f1e78f","article-title":"Acute coagulopathy of trauma: mechanism, identification and effect.","volume":"13","author":"Brohi","year":"2007","journal-title":"Curr Opin Crit Care"},{"key":"R21-9-20210902","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1097\/01.TA.0000075338.21177.EF","article-title":"Early coagulopathy predicts mortality in trauma.","volume":"55","author":"MacLeod","year":"2003","journal-title":"J Trauma"},{"key":"R22-9-20210902","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1097\/01.TA.0000069184.82147.06","article-title":"Acute traumatic coagulopathy.","volume":"54","author":"Brohi","year":"2003","journal-title":"J Trauma"},{"key":"R23-9-20210902","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1007\/s001130050719","article-title":"[Predicting the outcome in severe injuries: an analysis of 2069 patients from the trauma register of the German society of traumatology (DGU)].","volume":"104","author":"Rixen","year":"2001","journal-title":"Der Unfallchirurg"},{"key":"R24-9-20210902","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1111\/1475-6773.00041","article-title":"Concurrent prediction of hospital mortality and length of stay from risk factors on admission.","volume":"37","author":"Clark","year":"2002","journal-title":"Health Serv Res"},{"key":"R25-9-20210902","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1097\/00024382-200115020-00001","article-title":"Base deficit development and its prognostic significance in posttrauma critical illness: an analysis by the trauma registry of the Deutsche Gesellschaft fur unfallchirurgie.","volume":"15","author":"Rixen","year":"2001","journal-title":"Shock"},{"key":"R26-9-20210902","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/S1072-7515(02)01211-5","article-title":"Predictors of mortality in adult trauma patients: the physiologic trauma score is equivalent to the trauma and injury severity score.","volume":"194","author":"Kuhls","year":"2002","journal-title":"J Am Coll Surg"},{"key":"R27-9-20210902","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1097\/00005373-200208000-00007","article-title":"A brief episode of hypotension increases mortality in critically ill trauma patients.","volume":"53","author":"Zenati","year":"2002","journal-title":"J Trauma"},{"key":"R28-9-20210902","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1097\/00005373-198709000-00011","article-title":"Hypothermia in trauma victims: an ominous predictor of survival.","volume":"27","author":"Jurkovich","year":"1987","journal-title":"J Trauma"},{"key":"R29-9-20210902","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1093\/bja\/aei169","article-title":"Coagulopathy and blood component transfusion in trauma.","volume":"95","author":"Spahn","year":"2005","journal-title":"Br J Anaesth"},{"key":"R30-9-20210902","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1097\/00003246-200102000-00006","article-title":"Tissue factor pathway inhibitor response does not correlate with tissue factor-induced disseminated intravascular coagulation and multiple organ dysfunction syndrome in trauma patients.","volume":"29","author":"Gando","year":"2001","journal-title":"Crit Care Med"},{"key":"R31-9-20210902","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1055\/s-2001-18864","article-title":"Disseminated intravascular coagulation in trauma patients.","volume":"27","author":"Gando","year":"2001","journal-title":"Semin Thromb Hemost"},{"key":"R32-9-20210902","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1097\/01.sla.0000256862.79374.31","article-title":"Acute traumatic coagulopathy: initiated by hypoperfusion: modulated through the protein C pathway?","volume":"245","author":"Brohi","year":"2007","journal-title":"Ann Surg"},{"key":"R33-9-20210902","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1097\/shk.0b013e3180342439","article-title":"Role of the alternative pathway in the early complement activation following major trauma.","volume":"28","author":"Ganter","year":"2007","journal-title":"Shock"},{"key":"R34-9-20210902","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1097\/SLA.0b013e318162d616","article-title":"Angiopoietin-2, marker and mediator of endothelial activation with prognostic significance early after trauma?","volume":"247","author":"Ganter","year":"2008","journal-title":"Ann Surg"},{"key":"R35-9-20210902","first-page":"1254","article-title":"Early coagulopathy after traumatic brain injury: the role of hypoperfusion and the protein C pathway.","volume":"63","author":"Cohen","year":"2007","journal-title":"J Trauma"},{"key":"R36-9-20210902","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1097\/01.shk.0000209564.84822.f2","article-title":"The cellular, metabolic, and systemic consequences of aggressive fluid resuscitation strategies.","volume":"26","author":"Cotton","year":"2006","journal-title":"Shock"},{"key":"R37-9-20210902","article-title":"Standards for blood banks and transfusion services. 25th ed.","year":"2008"},{"key":"R38-9-20210902","doi-asserted-by":"crossref","first-page":"2197","DOI":"10.1111\/j.1537-2995.2007.01446.x","article-title":"Detection of anti-D in D\u2212recipients transfused with D+ red blood cells.","volume":"47","author":"Yazer","year":"2007","journal-title":"Transfusion"},{"key":"R39-9-20210902","doi-asserted-by":"crossref","first-page":"2014","DOI":"10.1111\/j.1537-2995.2006.01026.x","article-title":"Clinical consequences of red cell storage in the critically ill.","volume":"46","author":"Tinmouth","year":"2006","journal-title":"Transfusion"},{"key":"R40-9-20210902","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1111\/j.1537-2995.2008.01657.x","article-title":"Red cell age and loss of function: advance or SNO-job?","volume":"48","author":"Winslow","year":"2008","journal-title":"Transfusion"},{"key":"R41-9-20210902","doi-asserted-by":"crossref","first-page":"19165","DOI":"10.1073\/pnas.0708871105","article-title":"Clinical implications of the loss of vasoactive nitric oxide during red blood cell storage.","volume":"104","author":"Bonaventura","year":"2007","journal-title":"Proc Natl Acad Sci USA"},{"key":"R42-9-20210902","doi-asserted-by":"crossref","first-page":"2636","DOI":"10.1182\/blood-2008-01-115261","article-title":"The functional nitrite reductase activity of the heme-globins.","volume":"112","author":"Gladwin","year":"2008","journal-title":"Blood"},{"key":"R43-9-20210902","first-page":"794","article-title":"Transfusions in the less severely injured: does age of transfused blood affect outcomes?","volume":"65","author":"Weinberg","year":"2008","journal-title":"J Trauma"},{"key":"R44-9-20210902","doi-asserted-by":"crossref","first-page":"31S","DOI":"10.1111\/j.1537-2995.2007.01574.x","article-title":"Pharmacologic methods to reduce perioperative bleeding.","volume":"48","author":"Levy","year":"2008","journal-title":"Transfusion"},{"key":"R45-9-20210902","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1111\/j.1537-2995.2007.01604.x","article-title":"Basic science focus on blood substitutes: a summary of the NHLBI division of blood diseases and resources working group workshop, March 1, 2006.","volume":"48","author":"Estep","year":"2008","journal-title":"Transfusion"},{"key":"R46-9-20210902","doi-asserted-by":"crossref","first-page":"40S","DOI":"10.1111\/j.0041-1132.2004.04176.x","article-title":"Indications and contraindications of cell salvage.","volume":"44","author":"Jonathan","year":"2004","journal-title":"Transfusion"},{"key":"R47-9-20210902","first-page":"307","article-title":"Damage control resuscitation: directly addressing the early coagulopathy of trauma.","volume":"62","author":"Holcomb","year":"2007","journal-title":"J Trauma"},{"key":"R48-9-20210902","doi-asserted-by":"crossref","first-page":"176S","DOI":"10.1111\/j.1537-2995.2007.01381.x","article-title":"The blood bank: from provider to partner in treatment of massively bleeding patients.","volume":"47","author":"Johansson","year":"2007","journal-title":"Transfusion"},{"key":"R49-9-20210902","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1097\/01.shk.0000225403.15722.e9","article-title":"Key issues in advanced bleeding care in trauma.","volume":"26","author":"Rossaint","year":"2006","journal-title":"Shock"},{"key":"R50-9-20210902","first-page":"S1","article-title":"Early massive trauma transfusion: state of the art: editors introduction.","volume":"60","author":"Holcomb","year":"6","journal-title":"J Trauma"},{"key":"R51-9-20210902","first-page":"S91","article-title":"Massive transfusion practices around the globe and a suggestion for a common massive transfusion protocol.","volume":"60","author":"Malone","year":"2006","journal-title":"J Trauma"},{"key":"R52-9-20210902","first-page":"805","article-title":"The ratio of blood products transfused affects mortality in patients receiving massive transfusions at a combat support hospital.","volume":"63","author":"Borgman","year":"2007","journal-title":"J Trauma"},{"key":"R54-9-20210902","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1001\/archsurg.143.7.686","article-title":"A massive transfusion protocol to decrease blood component use and costs.","volume":"143","author":"O\u2019Keeffe","year":"2008","journal-title":"Arch Surg"},{"key":"R55-9-20210902","first-page":"1177","article-title":"Damage control hematology: the impact of a trauma exsanguination protocol on survival and blood product utilization.","volume":"64","author":"Cotton","year":"2008","journal-title":"J Trauma"},{"key":"R56-9-20210902","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1111\/j.1423-0410.2008.01074.x","article-title":"Red-blood-cell to plasma ratios transfused during massive transfusion are associated with mortality in severe multiple injury: a retrospective analysis from the trauma registry of the Deutsche Gesellschaft fur Unfallchirurgie.","volume":"95","author":"Maegele","year":"2008","journal-title":"Vox Sang"},{"key":"R57-9-20210902","first-page":"S79","article-title":"The ratio of fibrinogen to red cells transfused affects survival in casualties receiving massive transfusions at an army combat support hospital.","volume":"64","author":"Stinger","year":"2008","journal-title":"J Trauma"},{"key":"R58-9-20210902","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1097\/01.ta.0000250497.08101.8b","article-title":"Fresh frozen plasma should be given earlier to patients requiring massive transfusion.","volume":"62","author":"Gonzalez","year":"2007","journal-title":"J Trauma"},{"key":"R60-9-20210902","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1097\/00006565-200110000-00002","article-title":"Coagulation testing in pediatric blunt trauma patients.","volume":"17","author":"Holmes","year":"2001","journal-title":"Pediatr Emerg Care"},{"key":"R61-9-20210902","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1542\/peds.99.3.371","article-title":"Coagulopathy in pediatric abusive head trauma.","volume":"99","author":"Hymel","year":"1997","journal-title":"Pediatrics"},{"key":"R62-9-20210902","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1097\/00045391-200209000-00006","article-title":"Perioperative blood transfusion therapy in pediatric patients.","volume":"9","author":"Hume","year":"2002","journal-title":"Am J Ther"}],"container-title":["Anesthesia & Analgesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1213\/ane.0b013e3181a0b6c6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T14:30:20Z","timestamp":1786113020000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00000539-200906000-00009"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,6]]},"references-count":60,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2009]]}},"URL":"https:\/\/doi.org\/10.1213\/ane.0b013e3181a0b6c6","relation":{},"ISSN":["0003-2999"],"issn-type":[{"value":"0003-2999","type":"print"}],"subject":[],"published":{"date-parts":[[2009,6]]}}}