{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T17:22:08Z","timestamp":1786123328822,"version":"build-2736575974"},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,2]]},"DOI":"10.1213\/ane.0b013e3181ca03a4","type":"journal-article","created":{"date-parts":[[2010,1,15]],"date-time":"2010-01-15T02:32:58Z","timestamp":1263522778000},"page":"300-301","source":"Crossref","is-referenced-by-count":7,"title":["The Effects of Hydroxyethyl Starch on Cultured Renal Epithelial Cells"],"prefix":"10.1213","volume":"110","author":[{"given":"Ralf A.","family":"Claus","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maik","family":"Sossdorf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christiane","family":"Hartog","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-11-20210902","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1007\/s00134-009-1520-6","article-title":"PRO: hydroxyethylstarch can be safely used in the intensive care patient\u2014the renal debate.","volume":"35","author":"Boldt","year":"2009","journal-title":"Intensive Care Med"},{"key":"R2-11-20210902","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1007\/s00134-009-1521-5","article-title":"CONTRA: Hydroxyethyl starch solutions are unsafe in critically ill patients.","volume":"35","author":"Hartog","year":"2009","journal-title":"Intensive Care Med"},{"key":"R3-11-20210902","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1213\/01.ane.0000258224.44806.dd","article-title":"The pros and cons of hydroxyethyl starch solutions.","volume":"104","author":"Vincent","year":"2007","journal-title":"Anesth Analg"},{"key":"R4-11-20210902","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1097\/00000542-200510000-00014","article-title":"Synthetic colloids attenuate leukocyte-endothelial interactions by inhibition of integrin function.","volume":"103","author":"Nohe","year":"2005","journal-title":"Anesthesiology"},{"key":"R5-11-20210902","first-page":"451","article-title":"Hydroxyethyl starch inhibits NF-kappaB activation and prevents the expression of inflammatory mediators in endotoxic rats.","volume":"33","author":"Tian","year":"2003","journal-title":"Ann Clin Lab Sci"},{"key":"R6-11-20210902","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.jss.2006.02.028","article-title":"Effects of hydroxyethyl starch 130\/0.4 on pulmonary capillary leakage and cytokines production and NF-kappaB activation in CLP-induced sepsis in rats.","volume":"135","author":"Feng","year":"2006","journal-title":"J Surg Res"},{"key":"R7-11-20210902","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1213\/01.ane.0000220906.74517.99","article-title":"Hydroxyethyl starch exhibits antiinflammatory effects in the intestines of endotoxemic rats.","volume":"103","author":"Lv","year":"2006","journal-title":"Anesth Analg"},{"key":"R8-11-20210902","doi-asserted-by":"crossref","first-page":"1536","DOI":"10.1097\/CCM.0b013e318169f19a","article-title":"Mechanisms of the anti-inflammatory effects of hydroxyethyl starch demonstrated in a flow-based model of neutrophil recruitment by endothelial cells.","volume":"36","author":"Matharu","year":"2008","journal-title":"Crit Care Med"},{"key":"R9-11-20210902","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1097\/00000542-200701000-00016","article-title":"Influence of different strategies of volume replacement on the activity of matrix metalloproteinases: an in vitro and in vivo study.","volume":"106","author":"Volta","year":"2007","journal-title":"Anesthesiology"},{"key":"R10-11-20210902","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1056\/NEJMoa044057","article-title":"Comparison of three fluid solutions for resuscitation in dengue shock syndrome.","volume":"353","author":"Wills","year":"2005","journal-title":"N Engl J Med"},{"key":"R11-11-20210902","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1056\/NEJMoa070716","article-title":"Intensive insulin therapy and pentastarch resuscitation in severe sepsis.","volume":"358","author":"Brunkhorst","year":"2008","journal-title":"N Engl J Med"},{"key":"R12-11-20210902","first-page":"CD000567","article-title":"Colloids versus crystalloids for fluid resuscitation in critically ill patients.","author":"Perel","year":"2007","journal-title":"Cochrane Database Syst Rev"},{"key":"R13-11-20210902","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1016\/S0140-6736(00)04211-2","article-title":"Effects of hydroxyethylstarch and gelatin on renal function in severe sepsis: a multicentre randomised study.","volume":"357","author":"Schortgen","year":"2001","journal-title":"Lancet"},{"key":"R15-11-20210902","first-page":"E196","article-title":"Renal outcomes and mortality following hydroxyethyl starch resuscitation of critically ill patients: systematic review and meta-analysis of randomized trials.","volume":"3","author":"Zarychanski","year":"2009","journal-title":"Open Med"},{"key":"R16-11-20210902","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/j.jtcvs.2009.02.035","article-title":"Hetastarch increases the risk of bleeding complications in patients after off-pump coronary bypass surgery: a randomized clinical trial.","volume":"138","author":"Hecht-Dolnik","year":"2009","journal-title":"J Thorac Cardiovasc Surg"},{"key":"R17-11-20210902","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.1378\/chest.123.6.1853","article-title":"Volume expansion with albumin decreases mortality after coronary artery bypass graft surgery.","volume":"123","author":"Sedrakyan","year":"2003","journal-title":"Chest"},{"key":"R18-11-20210902","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1053\/j.ajkd.2007.10.044","article-title":"Osmotic nephrosis: acute kidney injury with accumulation of proximal tubular lysosomes due to administration of exogenous solutes.","volume":"51","author":"Dickenmann","year":"2008","journal-title":"Am J Kidney Dis"},{"key":"R19-11-20210902","doi-asserted-by":"crossref","first-page":"R23","DOI":"10.1186\/cc7726","article-title":"Hydroxyethylstarch impairs renal function and induces interstitial proliferation, macrophage infiltration and tubular damage in an isolated renal perfusion model.","volume":"13","author":"Huter","year":"2009","journal-title":"Crit Care"},{"key":"R20-11-20210902","first-page":"A82","article-title":"Hydroxyethyl starch solutions impair clot formation and platelet aggregation but enhance platelet surface receptor expression.","volume":"28","author":"Sossdorf","year":"2008","journal-title":"H\u00e4matologie"},{"key":"R21-11-20210902","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1213\/ANE.0b013e3181c03c97","article-title":"The effect of hydroxyethyl starches (HES 130\/0.42 and HES 200\/0.5) on activated renal tubular epithelial cells.","volume":"110","author":"Wittlinger","year":"2010","journal-title":"Anesth Analg"},{"key":"R22-11-20210902","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1111\/j.1600-6143.2005.00852.x","article-title":"Renal histopathological lesions after orthotopic liver transplantation (OLT).","volume":"5","author":"Pillebout","year":"2005","journal-title":"Am J Transplant"},{"key":"R23-11-20210902","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1007\/s00134-007-0716-x","article-title":"Pharmacodynamics and organ storage of hydroxyethyl starch in acute hemodilution in pigs: influence of molecular weight and degree of substitution.","volume":"33","author":"Eisenbach","year":"2007","journal-title":"Intensive Care Med"}],"container-title":["Anesthesia & Analgesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1213\/ANE.0b013e3181ca03a4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T14:15:50Z","timestamp":1786112150000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00000539-201002000-00011"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,2]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010]]}},"URL":"https:\/\/doi.org\/10.1213\/ane.0b013e3181ca03a4","relation":{},"ISSN":["0003-2999"],"issn-type":[{"value":"0003-2999","type":"print"}],"subject":[],"published":{"date-parts":[[2010,2]]}}}