{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T17:21:21Z","timestamp":1786123281214,"version":"build-2736575974"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,10]]},"DOI":"10.1213\/ane.0b013e318228a001","type":"journal-article","created":{"date-parts":[[2011,8,5]],"date-time":"2011-08-05T09:41:51Z","timestamp":1312537311000},"page":"858-861","source":"Crossref","is-referenced-by-count":16,"title":["Perioperative Exacerbation of Valproic Acid\u2013Associated Hyperammonemia"],"prefix":"10.1213","volume":"113","author":[{"given":"Dmitri","family":"Bezinover","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marek","family":"Postula","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen","family":"Donahue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Bentzen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"McInerney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piotr K.","family":"Janicki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-30-20210902","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1097\/YIC.0b013e3281c61b28","article-title":"Valproate-induced hyperammonaemic encephalopathy: review of 14 cases in the psychiatric setting.","volume":"22","author":"Dealberto","year":"2007","journal-title":"Int Clin Psychopharmacol"},{"key":"R2-30-20210902","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1111\/j.1460-9592.2010.03322.x","article-title":"Anesthetic implications of ornithine transcarbamylase deficiency.","volume":"20","author":"Dutoit","year":"2010","journal-title":"Pediatr Anesth"},{"key":"R3-30-20210902","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/s007260170016","article-title":"Conscientious metabolic monitoring on a patient with hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome undergoing anaesthesia.","volume":"21","author":"Muhling","year":"2001","journal-title":"Amino Acids"},{"key":"R4-30-20210902","doi-asserted-by":"crossref","first-page":"499","DOI":"10.3122\/jabfm.2007.05.070062","article-title":"Valproate-associated hyperammonemic encephalopathy.","volume":"20","author":"Wadzinski","year":"2007","journal-title":"J Am Board Fam Med"},{"key":"R5-30-20210902","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1212\/WNL.41.9.1444","article-title":"Alteration of renal carnitine metabolism by anticonvulsant treatment.","volume":"41","author":"Camina","year":"1991","journal-title":"Neurology"},{"key":"R6-30-20210902","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1177\/088307389701200709","article-title":"Asymptomatic hyperammonemia in children treated with valproic acid.","volume":"12","author":"Altunbasak","year":"1997","journal-title":"J Child Neurol"},{"key":"R7-30-20210902","first-page":"1037","article-title":"Evaluation of the effect of long term valproic acid treatment on plasma levels of carnitine, ammonia and amino acids related to the urea cycle in pediatric epileptic patients.","volume":"25","author":"Navarro-Quesada","year":"1997","journal-title":"Rev Neurol"},{"key":"R8-30-20210902","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1212\/WNL.33.9.1136","article-title":"The renal origin of sodium valproate induced hyperammonemia in fasting humans.","volume":"33","author":"Warter","year":"1983","journal-title":"Neurology"},{"key":"R9-30-20210902","doi-asserted-by":"crossref","first-page":"275","DOI":"10.3949\/ccjm.50.3.275","article-title":"Valproate induced hyperammonemia in asymptomatic children.","volume":"50","author":"Wyllie","year":"1983","journal-title":"Cleve Clin Q"},{"key":"R10-30-20210902","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1007\/BF00441418","article-title":"Hyperamino-acidaemia and hyperammonaemia in epileptic children treated with valproic acid.","volume":"148","author":"Iinuma","year":"1988","journal-title":"Eur J Pediatr"},{"key":"R11-30-20210902","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1007\/s001340100937","article-title":"Simultaneous side effects of both clozapine and valproate.","volume":"27","author":"Nicolai","year":"2001","journal-title":"Intensive Care Med"},{"key":"R12-30-20210902","doi-asserted-by":"crossref","first-page":"91","DOI":"10.2190\/XW8E-Q283-4429-QL71","article-title":"Ammonia induced encephalopathy from valproic acid in a bipolar patient: case report.","volume":"33","author":"Elgudin","year":"2003","journal-title":"Int J Psychiatry Med"},{"key":"R13-30-20210902","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1111\/j.1442-200X.2010.03157.x","article-title":"Effect of CPS1 4217CA genotype on valproic acid-induced hyperammonemia.","volume":"52","author":"Yagi","year":"2010","journal-title":"Pediatr Int"},{"key":"R15-30-20210902","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1111\/j.1460-9592.2005.01695.x","article-title":"Anesthetic management of patients with ornithine transcarbamylase deficiency.","volume":"16","author":"Schmidt","year":"2006","journal-title":"Paediatr Anaesth"},{"key":"R16-30-20210902","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1007\/s11940-003-0037-5","article-title":"Urea cycle disorders.","volume":"5","author":"Kleppe","year":"2003","journal-title":"Curr Treat Options Neurol"},{"key":"R18-30-20210902","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1177\/106002809302700510","article-title":"Valproate-induced coma: case report and literature review.","volume":"27","author":"Duarte","year":"1993","journal-title":"Ann Pharmacother"},{"key":"R19-30-20210902","doi-asserted-by":"crossref","first-page":"3963","DOI":"10.1016\/0006-2952(89)90675-8","article-title":"Valproate induced hyperammonemia of renal origin: effects of valproate on glutamine transport in rat kidney mitochondria.","volume":"38","author":"Rumbach","year":"1989","journal-title":"Biochem Pharmacol"},{"key":"R20-30-20210902","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1345\/aph.1E063","article-title":"Valproic acid-induced hyperammonemia and thrombocytopenia in an elderly woman.","volume":"38","author":"Mallet","year":"2004","journal-title":"Ann Pharmacother"},{"key":"R21-30-20210902","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1023\/A:1021918104127","article-title":"Valproate-induced hyperammonemic encephalopathy.","volume":"17","author":"Verrotti","year":"2002","journal-title":"Metab Brain Dis"}],"container-title":["Anesthesia & Analgesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1213\/ANE.0b013e318228a001","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T14:17:10Z","timestamp":1786112230000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00000539-201110000-00030"}},"subtitle":["A Clinical and Genetic Analysis"],"short-title":[],"issued":{"date-parts":[[2011,10]]},"references-count":19,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011]]}},"URL":"https:\/\/doi.org\/10.1213\/ane.0b013e318228a001","relation":{},"ISSN":["0003-2999"],"issn-type":[{"value":"0003-2999","type":"print"}],"subject":[],"published":{"date-parts":[[2011,10]]}}}