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Compared to conventional landmark prediction with fixed landmark times, our methods allow the landmark times to be subject-specific and triggered by an intermediate clinical event. Moreover, the nonparametric approach circumvents the thorny issue of model incompatibility at different landmark times. In our framework, both the longitudinal predictors and the event time outcome are subject to right censoring, and thus existing tree-based approaches cannot be directly applied. To tackle the analytical challenges, we propose a risk-set-based ensemble procedure by averaging martingale estimating equations from individual trees. Extensive simulation studies are conducted to evaluate the performance of our methods. The methods are applied to the Cystic Fibrosis Foundation Patient Registry (CFFPR) data to perform dynamic prediction of lung disease in cystic fibrosis patients and to identify important prognosis factors.<\/jats:p>","DOI":"10.1214\/22-aoas1674","type":"journal-article","created":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T18:28:15Z","timestamp":1682965695000},"page":"1375-1397","source":"Crossref","is-referenced-by-count":4,"title":["Dynamic risk prediction triggered by intermediate events using survival tree ensembles"],"prefix":"10.1214","volume":"17","author":[{"given":"Yifei","family":"Sun","sequence":"first","affiliation":[{"name":"Department of Biostatistics, Columbia University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sy Han","family":"Chiou","sequence":"additional","affiliation":[{"name":"Department of Mathematical Sciences, University of Texas at Dallas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colin O.","family":"Wu","sequence":"additional","affiliation":[{"name":"National Heart, Lung, and Blood Institute, National Institutes of Health"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meghan E.","family":"McGarry","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of California San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiung-Yu","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, University of California San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"108","reference":[{"key":"1","doi-asserted-by":"publisher","unstructured":"<small>Breiman, L.<\/small> (1996). 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