{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:45:21Z","timestamp":1792788321172,"version":"4.5.0"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","funder":[{"name":"National Natural Science Foundation of China","award":["82472085"],"award-info":[{"award-number":["82472085"]}],"id":[{"id":"https:\/\/ror.org\/01h0zpd94","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND AND OBJECTIVES:<\/jats:title>\n                    <jats:p>To evaluate the clinical and angiographic outcomes of endovascular treatment for posterior inferior cerebellar artery (PICA) aneurysms, emphasizing a location-specific treatment stratification based on PICA segmental anatomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>Patients with PICA aneurysms treated endovascularly between December 2016 and December 2024 were retrospectively analyzed. The PICA is classified into 5 segments, with the first 3 (P1-P3) designated as proximal and the P4-P5 as distal. We assessed the immediate and progressive aneurysm occlusion rates, procedure-related complications, and clinical outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>Forty-six patients (each with 1 PICA aneurysm; 37 ruptured) were included. Twenty-five aneurysms (54.3%) were located in the proximal PICA and 21 (45.7%) in the distal segments. Technical success was achieved in all procedures. Parent artery preservation was accomplished in all proximal aneurysms, treated with either coiling (n = 16) or stent-assisted coiling (n = 9). Most distal aneurysms (66.7%, 14\/21) were treated with parent artery occlusion. Intraprocedural ischemic events occurred in 4 patients (8.7%), with one fatal in-stent thrombosis. Intraprocedural aneurysm rupture occurred in one case (2.2%). Postprocedural infarction was observed in 3 patients (6.5%), all of whom had unfavorable clinical outcomes at follow-up. Immediate postprocedural angiography revealed complete occlusion (Raymond Grade I) in 67.4% (31\/46) of cases, increasing to 97.3% (36\/37) at follow-up, with no recurrence. Favorable clinical outcomes (modified Rankin Scale: 0-2) were achieved in 76.1% of patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>An anatomy-based tailored endovascular approach for PICA aneurysms yields encouraging clinical and angiographic outcomes, with proximal lesions amenable to coiling or stent-assisted coiling and distal lesions effectively managed with parent artery occlusion.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1227\/ons.0000000000002136","type":"journal-article","created":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T13:01:58Z","timestamp":1789563718000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["A Location-Based Tailored Endovascular Strategy for Managing Posterior Inferior Cerebellar Artery Aneurysms: A Single-Center 46-Case Series"],"prefix":"10.1227","author":[{"given":"Haibin","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongwei","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guosai","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenyu","family":"Jia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linbo","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,9,16]]},"reference":[{"issue":"10","key":"R1-20260916","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1136\/neurintsurg-2015-012070","article-title":"Endovascular 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