{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T01:37:12Z","timestamp":1790473032987,"version":"4.1.0"},"reference-count":78,"publisher":"The Company of Biologists","license":[{"start":{"date-parts":[[2021,5,18]],"date-time":"2021-05-18T00:00:00Z","timestamp":1621296000000},"content-version":"am","delay-in-days":1233,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology of Japan","doi-asserted-by":"crossref","award":["No. 45980001"],"award-info":[{"award-number":["No. 45980001"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>MDCK dog kidney epithelial cells express two isoforms of nonmuscle myosin heavy chain II, IIA and IIB. Using the CRISPR\/Cas9 system, we established cells in which the IIA gene was ablated. These cells were then transfected with a vector that expresses GFP\u2013IIA chimeric molecule under the control of tetracycline-responsible element. In the absence of Dox (doxycyclin), when GFP\u2013IIA is expressed (GFP\u2013IIA+), the cells exhibit epithelial cell morphology, but in the presence of Dox, when expression of GFP\u2013IIA is repressed (GFP\u2013IIA\u2212), the cells lose epithelial morphology and strong cell\u2013cell adhesion. Consistent with these observations, GFP\u2013IIA\u2212 cells failed to assemble junction components such as E-cadherin, desmoplakin, and occludin at cell\u2013cell contact sites. Therefore, IIA is required for assembly of junction complexes. MDCK cells with an ablation of the \u03b1-catenin gene also exhibited the same phenotype. However, when in GFP\u2013IIA\u2212 cells expressed \u03b1-catenin lacking the inhibitory region or E-cadherin\/\u03b1-catenin chimeras, the cells acquired the ability to establish the junction complex. These experiments reveal that IIA acts as an activator of \u03b1-catenin in junction assembly.<\/jats:p>","DOI":"10.1242\/bio.031369","type":"journal-article","created":{"date-parts":[[2018,4,13]],"date-time":"2018-04-13T15:55:15Z","timestamp":1523634915000},"source":"Crossref","is-referenced-by-count":23,"title":["Nonmuscle myosin IIA is involved in recruitment of apical junction components through activation of \u03b1-catenin"],"prefix":"10.1242","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7887-8441","authenticated-orcid":false,"given":"Masayuki","family":"Ozawa","sequence":"first","affiliation":[{"name":"Department of Biochemistry and Molecular Biology, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"237","published-online":{"date-parts":[[2018,1,1]]},"reference":[{"key":"2021042423141347100_BIO031369C1","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1073\/pnas.0710504105","article-title":"EPLIN mediates linkage of the cadherin catenin complex to F-actin and stabilizes the circumferential actin belt","volume":"105","author":"Abe","year":"2008","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2021042423141347100_BIO031369C2","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1111\/1523-1747.ep12613462","article-title":"Delayed assembly of desmosomes in keratinocytes with disrupted classic-cadherin-mediated cell adhesion by a dominant negative mutant","volume":"104","author":"Amagai","year":"1995","journal-title":"J. Invest. Dermatol."},{"key":"2021042423141347100_BIO031369C3","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1083\/jcb.136.3.693","article-title":"NH2-terminal deletion of \u03b2-catenin results in stable colocalization of mutant beta-catenin with adenomatous polyposis coli protein and altered MDCK cell adhesion","volume":"136","author":"Barth","year":"1997","journal-title":"J. Cell Biol."},{"key":"2021042423141347100_BIO031369C4","doi-asserted-by":"crossref","first-page":"6107","DOI":"10.1002\/j.1460-2075.1995.tb00301.x","article-title":"E-cadherin is a tumour\/invasion suppressor gene mutated in human lobular breast cancers","volume":"14","author":"Berx","year":"1995","journal-title":"EMBO J."},{"key":"2021042423141347100_BIO031369C5","doi-asserted-by":"publisher","first-page":"1065","DOI":"10.1083\/jcb.201411080","article-title":"Reevaluating \u03b1E-catenin monomer and homodimer functions by characterizing E-cadherin\/\u03b1E-catenin chimeras","volume":"210","author":"Bianchini","year":"2015","journal-title":"J. Cell Biol."},{"key":"2021042423141347100_BIO031369C6","doi-asserted-by":"publisher","first-page":"12568","DOI":"10.1073\/pnas.1204390109","article-title":"E-cadherin is under constitutive actomyosin-generated tension that is increased at cell-cell contacts upon externally applied stretch","volume":"109","author":"Borghi","year":"2012","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2021042423141347100_BIO031369C7","doi-asserted-by":"publisher","first-page":"1254211","DOI":"10.1126\/science.1254211","article-title":"Cell adhesion. The minimal cadherin-catenin complex binds to actin filaments under force","volume":"346","author":"Buckley","year":"2014","journal-title":"Science"},{"key":"2021042423141347100_BIO031369C8","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1083\/jcb.201412064","article-title":"\u03b1-Catenin-mediated cadherin clustering couples cadherin and actin dynamics","volume":"210","author":"Chen","year":"2015","journal-title":"J. Cell Biol."},{"key":"2021042423141347100_BIO031369C9","doi-asserted-by":"publisher","first-page":"8576","DOI":"10.1073\/pnas.1203906109","article-title":"\u03b1E-catenin is an autoinhibited molecule that coactivates vinculin","volume":"109","author":"Choi","year":"2012","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2021042423141347100_BIO031369C10","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1126\/science.1231143","article-title":"Multiplex genome engineering using CRISPR\/Cas systems","volume":"339","author":"Cong","year":"2013","journal-title":"Science"},{"key":"2021042423141347100_BIO031369C11","doi-asserted-by":"publisher","first-page":"41263","DOI":"10.1074\/jbc.C400352200","article-title":"Defects in cell adhesion and the visceral endoderm following ablation of nonmuscle myosin heavy chain II-A in mice","volume":"279","author":"Conti","year":"2004","journal-title":"J. Biol. Chem."},{"key":"2021042423141347100_BIO031369C1114","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1242\/jcs.007112","article-title":"Nonmuscle myosin II moves in new directions","volume":"121","author":"Conti","year":"2008","journal-title":"J. Cell Sci"},{"key":"2021042423141347100_BIO031369C12","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1038\/ncb2685","article-title":"Monomeric \u03b1-catenin links cadherin to the actin cytoskeleton","volume":"15","author":"Desai","year":"2013","journal-title":"Nat. Cell Biol."},{"key":"2021042423141347100_BIO031369C13","doi-asserted-by":"publisher","first-page":"903","DOI":"10.1016\/j.cell.2005.09.021","article-title":"\u03b1-catenin is a molecular switch that binds E-cadherin-\u03b2-catenin and regulates actin-filament assembly","volume":"123","author":"Drees","year":"2005","journal-title":"Cell"},{"key":"2021042423141347100_BIO031369C14","doi-asserted-by":"publisher","first-page":"1150","DOI":"10.1242\/jcs.163824","article-title":"\u03b1-Catenin phosphorylation promotes intercellular adhesion through a dual-kinase mechanism","volume":"128","author":"Escobar","year":"2015","journal-title":"J. Cell Sci."},{"key":"2021042423141347100_BIO031369C15","doi-asserted-by":"publisher","first-page":"4127","DOI":"10.1073\/pnas.77.7.4127","article-title":"Vinculin, an intracellular protein localized at specialized sites where microfilament bundles terminate at cell membranes","volume":"77","author":"Geiger","year":"1980","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2021042423141347100_BIO031369C16","doi-asserted-by":"publisher","first-page":"1523","DOI":"10.1083\/jcb.101.4.1523","article-title":"Molecular heterogeneity of adherens junctions","volume":"101","author":"Geiger","year":"1985","journal-title":"J. Cell Biol."},{"key":"2021042423141347100_BIO031369C111","doi-asserted-by":"publisher","first-page":"2800","DOI":"10.1074\/jbc.M309981200","article-title":"Identification and characterization of nonmuscle myosin II-C, a new member of the myosin II family","volume":"279","author":"Golomb","year":"2004","journal-title":"J. Biol. Chem."},{"key":"2021042423141347100_BIO031369C17","doi-asserted-by":"publisher","first-page":"5547","DOI":"10.1073\/pnas.89.12.5547","article-title":"Tight control of gene expression in mammalian cells by tetracycline-responsive promoters","volume":"89","author":"Gossen","year":"1992","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2021042423141347100_BIO031369C18","doi-asserted-by":"publisher","first-page":"1575","DOI":"10.1083\/jcb.107.4.1575","article-title":"The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex","volume":"107","author":"Gumbiner","year":"1988","journal-title":"J. Cell Biol."},{"key":"2021042423141347100_BIO031369C19","doi-asserted-by":"publisher","first-page":"9156","DOI":"10.1073\/pnas.88.20.9156","article-title":"The uvomorulin-anchorage protein \u03b1 catenin is a vinculin homologue","volume":"88","author":"Herrenknecht","year":"1991","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2021042423141347100_BIO031369C20","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1083\/jcb.201108120","article-title":"Vinculin associates with endothelial VE-cadherin junctions to control force-dependent remodeling","volume":"196","author":"Huveneers","year":"2012","journal-title":"J. Cell Biol."},{"key":"2021042423141347100_BIO031369C21","doi-asserted-by":"publisher","first-page":"939","DOI":"10.1111\/j.0022-202X.2005.23714.x","article-title":"In vitro keratinocyte dissociation assay for evaluation of the pathogenicity of anti-desmoglein 3 IgG autoantibodies in pemphigus vulgaris","volume":"124","author":"Ishii","year":"2005","journal-title":"J. Invest. Dermatol."},{"key":"2021042423141347100_BIO031369C22","doi-asserted-by":"publisher","first-page":"15913","DOI":"10.1074\/jbc.M113.453928","article-title":"An autoinhibited structure of \u03b1-catenin and its implications for vinculin recruitment to adherens junctions","volume":"288","author":"Ishiyama","year":"2013","journal-title":"J. Biol. Chem."},{"key":"2021042423141347100_BIO031369C23","doi-asserted-by":"publisher","first-page":"2639","DOI":"10.1091\/mbc.E04-02-0163","article-title":"Role for actin filament turnover and a myosin II motor in cytoskeleton-driven disassembly of the epithelial apical junctional complex","volume":"15","author":"Ivanov","year":"2004","journal-title":"Mol. Biol. Cell"},{"key":"2021042423141347100_BIO031369C1115","doi-asserted-by":"publisher","first-page":"816","DOI":"10.1126\/science.1225829","article-title":"A programmable dual-RNAguided DNA endonuclease in adaptive bacterial immunity","volume":"337","author":"Jinek","year":"2012","journal-title":"Science"},{"key":"2021042423141347100_BIO031369C24","doi-asserted-by":"publisher","first-page":"4496","DOI":"10.1242\/jcs.193268","article-title":"\u03b1-Catenin stabilises Cadherin-Catenin complexes and modulates actomyosin dynamics to allow pulsatile apical contraction","volume":"129","author":"Jurado","year":"2016","journal-title":"J. Cell Sci."},{"key":"2021042423141347100_BIO031369C25","doi-asserted-by":"publisher","first-page":"7077","DOI":"10.1074\/jbc.M116.769778","article-title":"Structural and functional characterization of Caenorhabditis elegans \u03b1-catenin reveals constitutive binding to \u03b2-catenin and F-actin","volume":"292","author":"Kang","year":"2017","journal-title":"J. Biol. Chem."},{"key":"2021042423141347100_BIO031369C26","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1016\/j.cub.2014.11.017","article-title":"Dynamic visualization of \u03b1-catenin reveals rapid, reversible conformation switching between tension states","volume":"25","author":"Kim","year":"2015","journal-title":"Curr. Biol."},{"key":"2021042423141347100_BIO031369C27","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1083\/jcb.130.1.67","article-title":"Interaction of \u03b1-actinin with the cadherin\/catenin cell-cell adhesion complex via \u03b1-catenin","volume":"130","author":"Knudsen","year":"1995","journal-title":"J. Cell Biol."},{"key":"2021042423141347100_BIO031369C28","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1038\/ncb1075","article-title":"Mammalian formin-1 participates in adherens junctions and polymerization of linear actin cables","volume":"6","author":"Kobielak","year":"2004","journal-title":"Nat. Cell Biol."},{"key":"2021042423141347100_BIO031369C1113","doi-asserted-by":"publisher","first-page":"4745","DOI":"10.1091\/mbc.E03-04-0205","article-title":"Asymmetric distribution of myosin IIB in migrating endothelial cells is regulated by a Rho-dependent kinase and contributes to tail retraction","volume":"14","author":"Kolega","year":"2003","journal-title":"Mol. Biol. Cell"},{"key":"2021042423141347100_BIO031369C29","doi-asserted-by":"publisher","first-page":"4025","DOI":"10.1016\/j.yexcr.2007.07.035","article-title":"Nucleation and growth of cadherin adhesions","volume":"313","author":"Lambert","year":"2007","journal-title":"Exp. Cell Res."},{"key":"2021042423141347100_BIO031369C30","doi-asserted-by":"publisher","first-page":"8263","DOI":"10.1073\/pnas.91.17.8263","article-title":"E-cadherin null mutant embryos fail to form a trophectoderm epithelium","volume":"91","author":"Larue","year":"1994","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2021042423141347100_BIO031369C31","doi-asserted-by":"publisher","first-page":"1107","DOI":"10.1083\/jcb.201001149","article-title":"Vinculin potentiates E-cadherin mechanosensing and is recruited to actin-anchored sites within adherens junctions in a myosin II-dependent manner","volume":"189","author":"le Duc","year":"2010","journal-title":"J. Cell Biol."},{"key":"2021042423141347100_BIO031369C32","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1083\/jcb.200612042","article-title":"Myosin VI and vinculin cooperate during the morphogenesis of cadherin cell-cell contacts in mammalian epithelial cells","volume":"178","author":"Maddugoda","year":"2007","journal-title":"J. Cell Biol."},{"key":"2021042423141347100_BIO031369C33","doi-asserted-by":"publisher","first-page":"823","DOI":"10.1126\/science.1232033","article-title":"RNA-guided human genome engineering via Cas9","volume":"339","author":"Mali","year":"2013","journal-title":"Science"},{"key":"2021042423141347100_BIO031369C34","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1083\/jcb.200103097","article-title":"Expression of \u03b1-catenin in \u03b1-catenin\u2013deficient cells increases resistance to sphingosine-induced apoptosis","volume":"154","author":"Matsubara","year":"2001","journal-title":"J. Cell Biol."},{"key":"2021042423141347100_BIO031369C35","doi-asserted-by":"crossref","first-page":"3077","DOI":"10.1242\/jcs.107.11.3077","article-title":"Differential localization of myosin-II isozymes in human cultured cells and blood cells","volume":"107","author":"Maupin","year":"1994","journal-title":"J. Cell Sci."},{"key":"2021042423141347100_BIO031369C36","doi-asserted-by":"publisher","first-page":"1637","DOI":"10.1016\/j.yexcr.2006.01.031","article-title":"Actomyosin tension is required for correct recruitment of adherens junction components and zonula occludens formation","volume":"312","author":"Miyake","year":"2006","journal-title":"Exp. Cell Res."},{"key":"2021042423141347100_BIO031369C1117","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1083\/jcb.127.1.235","article-title":"The roles of catenins in the cadherin-mediated cell adhesion: functional analysis of E-cadherin-alpha catenin fusion molecules","volume":"127","author":"Nagafuchi","year":"1994","journal-title":"J. Cell Biol."},{"key":"2021042423141347100_BIO031369C37","doi-asserted-by":"publisher","first-page":"849","DOI":"10.1016\/0092-8674(91)90392-C","article-title":"The 102 kd cadherin-associated protein: similarity to vinculin and posttranscriptional regulation of expression","volume":"65","author":"Nagafuchi","year":"1991","journal-title":"Cell"},{"key":"2021042423141347100_BIO031369C38","doi-asserted-by":"publisher","first-page":"29524","DOI":"10.1074\/jbc.273.45.29524","article-title":"Identification of the region of \u03b1-catenin that plays an essential role in cadherin-mediated cell adhesion","volume":"273","author":"Ozawa","year":"1998","journal-title":"J. Biol. Chem."},{"key":"2021042423141347100_BIO031369C39","doi-asserted-by":"publisher","first-page":"19600","DOI":"10.1074\/jbc.M202029200","article-title":"Lateral dimerization of the E-cadherin extracellular domain is necessary but not sufficient for adhesive activity","volume":"277","author":"Ozawa","year":"2002","journal-title":"J. Biol. Chem."},{"key":"2021042423141347100_BIO031369C40","doi-asserted-by":"publisher","first-page":"1427","DOI":"10.1242\/bio.013938","article-title":"E-cadherin cytoplasmic domain inhibits cell surface localization of endogenous cadherins and fusion of C2C12 myoblasts","volume":"4","author":"Ozawa","year":"2015","journal-title":"Biol. Open"},{"key":"2021042423141347100_BIO031369C41","doi-asserted-by":"publisher","first-page":"e105313","DOI":"10.1371\/journal.pone.0105313","article-title":"Cadherin cytoplasmic domains inhibit the cell surface localization of endogenous E-cadherin, blocking desmosome and tight junction formation and inducing cell dissociation","volume":"9","author":"Ozawa","year":"2014","journal-title":"PLoS ONE"},{"key":"2021042423141347100_BIO031369C42","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1002\/j.1460-2075.1989.tb03563.x","article-title":"The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species","volume":"8","author":"Ozawa","year":"1989","journal-title":"EMBO J."},{"key":"2021042423141347100_BIO031369C43","doi-asserted-by":"publisher","first-page":"18868","DOI":"10.1074\/jbc.M201463200","article-title":"Biochemical and structural definition of the l-afadin- and actin-binding sites of \u03b1-catenin","volume":"277","author":"Pokutta","year":"2002","journal-title":"J. Biol. Chem."},{"key":"2021042423141347100_BIO031369C44","doi-asserted-by":"publisher","first-page":"18492","DOI":"10.1074\/jbc.M112.351023","article-title":"The cytoskeletal protein \u03b1-catenin unfurls upon binding to vinculin","volume":"287","author":"Rangarajan","year":"2012","journal-title":"J. Biol. Chem."},{"key":"2021042423141347100_BIO031369C45","doi-asserted-by":"publisher","first-page":"855","DOI":"10.1073\/pnas.92.3.855","article-title":"A targeted mutation in the mouse E-cadherin gene results in defective preimplantation development","volume":"92","author":"Riethmacher","year":"1995","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2021042423141347100_BIO031369C46","doi-asserted-by":"publisher","first-page":"8813","DOI":"10.1073\/pnas.92.19.8813","article-title":"\u03b11(E)-catenin is an actin-binding and -bundling protein mediating the attachment of F-actin to the membrane adhesion complex","volume":"92","author":"Rimm","year":"1995","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2021042423141347100_BIO031369C47","doi-asserted-by":"publisher","first-page":"1175","DOI":"10.1083\/jcb.153.6.1175","article-title":"Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism","volume":"153","author":"Riveline","year":"2001","journal-title":"J. Cell Biol."},{"key":"2021042423141347100_BIO031369C48","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1111\/xen.12089","article-title":"The combinational use of CRISPR\/Cas9-based gene editing and targeted toxin technology enables efficient biallelic knockout of the \u03b1-1,3-galactosyltransferase gene in porcine embryonic fibroblasts","volume":"21","author":"Sato","year":"2014","journal-title":"Xenotransplantation"},{"key":"2021042423141347100_BIO031369C49","first-page":"6328","article-title":"E-cadherin expression in squamous cell carcinomas of head and neck: inverse correlation with tumor dedifferentiation and lymph node metastasis","volume":"51","author":"Schipper","year":"1991","journal-title":"Cancer Res."},{"key":"2021042423141347100_BIO031369C50","doi-asserted-by":"publisher","first-page":"4531","DOI":"10.1091\/mbc.E05-04-0330","article-title":"Myosin 2 is a key Rho kinase target necessary for the local concentration of E-cadherin at cell-cell contacts","volume":"16","author":"Shewan","year":"2005","journal-title":"Mol. Biol. Cell"},{"key":"2021042423141347100_BIO031369C51","doi-asserted-by":"publisher","first-page":"2921","DOI":"10.2353\/ajpath.2010.100397","article-title":"Plakoglobin rescues adhesive defects induced by ectodomain truncation of the desmosomal cadherin desmoglein 1: implications for exfoliative toxin-mediated skin blistering","volume":"177","author":"Simpson","year":"2010","journal-title":"Am. J. Pathol."},{"key":"2021042423141347100_BIO031369C52","doi-asserted-by":"publisher","first-page":"696","DOI":"10.1038\/ncb2072","article-title":"Myosin II isoforms identify distinct functional modules that support integrity of the epithelial zonula adherens","volume":"12","author":"Smutny","year":"2010","journal-title":"Nat. Cell Biol."},{"key":"2021042423141347100_BIO031369C53","doi-asserted-by":"publisher","first-page":"1743","DOI":"10.1126\/science.1081412","article-title":"Dissecting temporal and spatial control of cytokinesis with a myosin II inhibitor","volume":"299","author":"Straight","year":"2003","journal-title":"Science"},{"key":"2021042423141347100_BIO031369C54","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1186\/1471-2121-12-48","article-title":"Myosin II activity dependent and independent vinculin recruitment to the sites of E-cadherin-mediated cell-cell adhesion","volume":"12","author":"Sumida","year":"2011","journal-title":"BMC Cell Biol."},{"key":"2021042423141347100_BIO031369C55","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1038\/nrm3802","article-title":"Dynamic contacts: rearranging adherens junctions to drive epithelial remodelling","volume":"15","author":"Takeichi","year":"2014","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"2021042423141347100_BIO031369C56","doi-asserted-by":"publisher","first-page":"1003","DOI":"10.3892\/ijmm.16.6.1003","article-title":"Identification of regions of \u03b1-catenin required for desmosome organization in epithelial cells","volume":"16","author":"Taniguchi","year":"2005","journal-title":"Int. J. Mol. Med."},{"key":"2021042423141347100_BIO031369C57","doi-asserted-by":"publisher","first-page":"21437","DOI":"10.1074\/jbc.270.37.21437","article-title":"Oocyte Gal\u03b11,3Gal epitopes implicated in sperm adhesion to the zona pellucida glycoprotein ZP3 are not required for fertilization in the mouse","volume":"270","author":"Thall","year":"1995","journal-title":"J. Biol. Chem."},{"key":"2021042423141347100_BIO031369C58","doi-asserted-by":"publisher","first-page":"4957","DOI":"10.1074\/jbc.M112.403774","article-title":"\u03b1-Catenin and vinculin cooperate to promote high E-cadherin-based adhesion strength","volume":"288","author":"Thomas","year":"2013","journal-title":"J. Biol. Chem."},{"key":"2021042423141347100_BIO031369C59","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1091\/mbc.E03-06-0430","article-title":"Nonmuscle myosin IIA and IIB have distinct functions in the exocytosis-dependent process of cell membrane repair","volume":"15","author":"Togo","year":"2004","journal-title":"Mol. Biol. Cell"},{"key":"2021042423141347100_BIO031369C60","doi-asserted-by":"publisher","first-page":"901","DOI":"10.1073\/pnas.94.3.901","article-title":"An \u03b1-E-catenin gene trap mutation defines its function in preimplantation development","volume":"94","author":"Torres","year":"1997","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2021042423141347100_BIO031369C61","doi-asserted-by":"publisher","first-page":"1128","DOI":"10.1242\/bio.20122428","article-title":"Vinculin-dependent Cadherin mechanosensing regulates efficient epithelial barrier formation","volume":"1","author":"Twiss","year":"2012","journal-title":"Biol. Open"},{"key":"2021042423141347100_BIO031369C62","doi-asserted-by":"publisher","first-page":"778","DOI":"10.1038\/nrm2786","article-title":"Non-muscle myosin II takes centre stage in cell adhesion and migration","volume":"10","author":"Vicente-Manzanares","year":"2009","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"2021042423141347100_BIO031369C63","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1016\/0092-8674(91)90143-M","article-title":"Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role","volume":"66","author":"Vleminckx","year":"1991","journal-title":"Cell"},{"key":"2021042423141347100_BIO031369C64","doi-asserted-by":"publisher","first-page":"14645","DOI":"10.1073\/pnas.1004023107","article-title":"Nonmuscle myosin II isoform and domain specificity during early mouse development","volume":"107","author":"Wang","year":"2010","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2021042423141347100_BIO031369C65","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1083\/jcb.127.1.247","article-title":"Induction of polarized cell-cell association and retardation of growth by activation of the E-cadherin-catenin adhesion system in a dispersed carcinoma line","volume":"127","author":"Watabe","year":"1994","journal-title":"J. Cell Biol."},{"key":"2021042423141347100_BIO031369C66","doi-asserted-by":"publisher","first-page":"847","DOI":"10.1083\/jcb.142.3.847","article-title":"\u03b1-Catenin-vinculin interaction functions to organize the apical junctional complex in epithelial cells","volume":"142","author":"Watabe-Uchida","year":"1998","journal-title":"J. Cell Biol."},{"key":"2021042423141347100_BIO031369C67","doi-asserted-by":"publisher","first-page":"3617","DOI":"10.1091\/mbc.11.10.3617","article-title":"Conditional expression of a truncated fragment of nonmuscle myosin II-A alters cell shape but not cytokinesis in HeLa cells","volume":"11","author":"Wei","year":"2000","journal-title":"Mol. Biol. Cell"},{"key":"2021042423141347100_BIO031369C1112","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1038\/35050613","article-title":"Separate but linked functions of conventional myosins modulate adhesion and neurite outgrowth","volume":"3","author":"Wylie","year":"2001","journal-title":"Nat. Cell Biol."},{"key":"2021042423141347100_BIO031369C68","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1242\/dev.125.2.327","article-title":"Vinculin knockout results in heart and brain defects during embryonic development","volume":"125","author":"Xu","year":"1998","journal-title":"Development"},{"key":"2021042423141347100_BIO031369C69","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1016\/j.cell.2005.09.020","article-title":"Deconstructing the cadherin-catenin-actin complex","volume":"123","author":"Yamada","year":"2005","journal-title":"Cell"},{"key":"2021042423141347100_BIO031369C70","doi-asserted-by":"publisher","first-page":"3645","DOI":"10.1093\/emboj\/20.14.3645","article-title":"Crystal structure of the M-fragment of \u03b1-catenin: implications for modulation of cell adhesion","volume":"20","author":"Yang","year":"2001","journal-title":"EMBO J."},{"key":"2021042423141347100_BIO031369C71","doi-asserted-by":"publisher","first-page":"4525","DOI":"10.1038\/ncomms5525","article-title":"Force-dependent conformational switch of \u03b1-catenin controls vinculin binding","volume":"5","author":"Yao","year":"2014","journal-title":"Nat. Commun."},{"key":"2021042423141347100_BIO031369C72","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1038\/ncb2055","article-title":"\u03b1-Catenin as a tension transducer that induces adherens junction development","volume":"12","author":"Yonemura","year":"2010","journal-title":"Nat. Cell Biol."}],"container-title":["Biology Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1242\/bio.031369","content-type":"unspecified","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/journals.logists.com\/bio\/bio\/article-pdf\/doi\/10.1242\/bio.031369\/1828626\/bio031369.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/journals.logists.com\/bio\/bio\/article-pdf\/doi\/10.1242\/bio.031369\/2051050\/bio_031369v1.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"http:\/\/journals.logists.com\/bio\/bio\/article-pdf\/doi\/10.1242\/bio.031369\/2051050\/bio_031369v1.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,19]],"date-time":"2022-08-19T14:53:33Z","timestamp":1660920813000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.biologists.com\/bio\/article\/doi\/10.1242\/bio.031369\/259398\/Nonmuscle-myosin-IIA-is-involved-in-recruitment-of"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,1]]},"references-count":78,"URL":"https:\/\/doi.org\/10.1242\/bio.031369","relation":{},"ISSN":["2046-6390"],"issn-type":[{"value":"2046-6390","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1,1]]},"article-number":"bio.031369"}}