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Our investigations manipulating the presence and activity of GLO-1\/Rab32 reveal that LRO biogenesis remains active during embryogenesis when the steady-state number of gut granules does not change. These studies define a system where the de novo formation of LROs can be investigated and provide insights into the mechanisms maintaining LROs once they have been generated.<\/jats:p>","DOI":"10.1242\/bio.062526","type":"journal-article","created":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T07:44:52Z","timestamp":1789458292000},"source":"Crossref","is-referenced-by-count":0,"title":["The\n                    <i>de novo<\/i>\n                    formation and maintenance of\n                    <i>C. elegans<\/i>\n                    lysosome-related organelles"],"prefix":"10.1242","volume":"15","author":[{"given":"Madeline","family":"Daniel","sequence":"first","affiliation":[{"name":"Lewis and Clark College Department of Biology , , 615 S. 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