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Analysis of two well-defined models of altered spermatogenesis(W\/Wv mutants and cryptorchid male mice) and RNA expression studies of differentiation markers demonstrate that germinal `Side Population' contains spermatogonial cells. In addition,\u03b1 6-integrin and Stra8 germinal stem cell markers, are expressed in the `Side Population'. In vivo repopulation assay clearly establishes that testis `Side Population' in adult mice is highly enriched in male germ stem cells.<\/jats:p>","DOI":"10.1242\/dev.00918","type":"journal-article","created":{"date-parts":[[2003,12,23]],"date-time":"2003-12-23T01:12:50Z","timestamp":1072141970000},"page":"479-487","source":"Crossref","is-referenced-by-count":125,"title":["`Side Population' cells in adult mouse testis express<i>Bcrp1<\/i>gene and are enriched in spermatogonia and germinal stem cells"],"prefix":"10.1242","volume":"131","author":[{"given":"Bruno","family":"Lassalle","sequence":"first","affiliation":[{"name":"Laboratoire de Me\u0301iose et de Maturation Game\u0301tique, DRR \/ DSV\/ CEA\u2013 U566 INSERM \u2013 Universite\u0301 Paris 7, Fontenay aux Roses,France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henri","family":"Bastos","sequence":"additional","affiliation":[{"name":"Laboratoire de Radiosensibilite\u0301 des Cellules Germinales, DRR \/ DSV\/ CEA\u2013 U566 INSERM \u2013 Universite\u0301 Paris 7, Fontenay aux Roses,France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean Paul","family":"Louis","sequence":"additional","affiliation":[{"name":"CNRS FRE 2358, Ge\u0301ne\u0301tique Expe\u0301rimentale et Mole\u0301culaire, Orle\u0301ans, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lydia","family":"Riou","sequence":"additional","affiliation":[{"name":"Laboratoire de Radiosensibilite\u0301 des Cellules Germinales, DRR \/ DSV\/ CEA\u2013 U566 INSERM \u2013 Universite\u0301 Paris 7, Fontenay aux Roses,France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacques","family":"Testart","sequence":"additional","affiliation":[{"name":"Laboratoire de Me\u0301iose et de Maturation Game\u0301tique, DRR \/ DSV\/ CEA\u2013 U566 INSERM \u2013 Universite\u0301 Paris 7, Fontenay aux Roses,France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"Dutrillaux","sequence":"additional","affiliation":[{"name":"Laboratoire de Radiosensibilite\u0301 des Cellules Germinales, DRR \/ DSV\/ CEA\u2013 U566 INSERM \u2013 Universite\u0301 Paris 7, Fontenay aux Roses,France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Fouchet","sequence":"additional","affiliation":[{"name":"Laboratoire de Radiosensibilite\u0301 des Cellules Germinales, DRR \/ DSV\/ CEA\u2013 U566 INSERM \u2013 Universite\u0301 Paris 7, Fontenay aux Roses,France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Allemand","sequence":"additional","affiliation":[{"name":"Laboratoire de Radiosensibilite\u0301 des Cellules Germinales, DRR \/ DSV\/ CEA\u2013 U566 INSERM \u2013 Universite\u0301 Paris 7, Fontenay aux Roses,France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"237","reference":[{"key":"2021042605055800000_REF1","unstructured":"Allen, J. 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