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Double-mutant analysis revealed a redundancy with AtSCAR4. Systematic application of the yeast two-hybrid system and Bimolecular Fluorescence Complementation (BiFC)revealed a complex protein-interaction network between the ARP2-ARP3 complex and its genetically defined regulators. In addition to protein interactions known in other systems, we identified several new interactions, suggesting that SPIKE1 may be an integral component of the SCAR\/WAVE complex and that SCAR proteins in plants might act as direct effectors of ROP GTPases.<\/jats:p>","DOI":"10.1242\/dev.02792","type":"journal-article","created":{"date-parts":[[2007,2,3]],"date-time":"2007-02-03T01:08:24Z","timestamp":1170464904000},"page":"967-977","source":"Crossref","is-referenced-by-count":94,"title":["The role of<i>Arabidopsis SCAR<\/i>genes in ARP2-ARP3-dependent cell morphogenesis"],"prefix":"10.1242","volume":"134","author":[{"given":"Joachim F.","family":"Uhrig","sequence":"first","affiliation":[{"name":"University of Ko\u0308ln, Botanical Institute III, Gyrhofstr. 15, 50931 Ko\u0308ln, Germany."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moola","family":"Mutondo","sequence":"additional","affiliation":[{"name":"University of Ko\u0308ln, Botanical Institute III, Gyrhofstr. 15, 50931 Ko\u0308ln, Germany."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilona","family":"Zimmermann","sequence":"additional","affiliation":[{"name":"University of Ko\u0308ln, Botanical Institute III, Gyrhofstr. 15, 50931 Ko\u0308ln, Germany."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael J.","family":"Deeks","sequence":"additional","affiliation":[{"name":"The Integrative Cell Biology Laboratory, School of Biological and Biomedical Sciences, University of Durham, South Road, Durham DH1 3LE, UK."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura M.","family":"Machesky","sequence":"additional","affiliation":[{"name":"School of Biosciences, Division of Molecular Cell Biology, University of Birmingham, Birmingham B15 2TT, UK."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philipp","family":"Thomas","sequence":"additional","affiliation":[{"name":"University of Ko\u0308ln, Botanical Institute III, Gyrhofstr. 15, 50931 Ko\u0308ln, Germany."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silke","family":"Uhrig","sequence":"additional","affiliation":[{"name":"University of Ko\u0308ln, Botanical Institute III, Gyrhofstr. 15, 50931 Ko\u0308ln, Germany."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Rambke","sequence":"additional","affiliation":[{"name":"University of Ko\u0308ln, Botanical Institute III, Gyrhofstr. 15, 50931 Ko\u0308ln, Germany."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick J.","family":"Hussey","sequence":"additional","affiliation":[{"name":"The Integrative Cell Biology Laboratory, School of Biological and Biomedical Sciences, University of Durham, South Road, Durham DH1 3LE, UK."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Hu\u0308lskamp","sequence":"additional","affiliation":[{"name":"University of Ko\u0308ln, Botanical Institute III, Gyrhofstr. 15, 50931 Ko\u0308ln, Germany."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"237","reference":[{"key":"2021042605472918200_REF1","doi-asserted-by":"crossref","unstructured":"Amann, K. and Pollard, T. 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