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We summarise how these approaches have revealed intrinsic programs that drive locally autonomous modes of organogenesis and homeostasis. We also attempt to interpret the results of previous in vivo studies of retinal development in light of the self-organising nature of the retina.<\/jats:p>","DOI":"10.1242\/dev.079590","type":"journal-article","created":{"date-parts":[[2012,10,23]],"date-time":"2012-10-23T08:45:25Z","timestamp":1350981925000},"page":"4111-4121","source":"Crossref","is-referenced-by-count":195,"title":["In vitro organogenesis in three dimensions: self-organising stem cells"],"prefix":"10.1242","volume":"139","author":[{"given":"Yoshiki","family":"Sasai","sequence":"first","affiliation":[{"name":"Neurogenesis and Organogenesis Group, RIKEN Center for Developmental Biology, Kobe, 650-0047, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mototsugu","family":"Eiraku","sequence":"additional","affiliation":[{"name":"Unit of Four-Dimensional Tissue Analysis, RIKEN Center for Developmental Biology, Kobe, 650-0047, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidetaka","family":"Suga","sequence":"additional","affiliation":[{"name":"Neurogenesis and Organogenesis Group, RIKEN Center for Developmental Biology, Kobe, 650-0047, Japan"},{"name":"Unit of Four-Dimensional Tissue Analysis, RIKEN Center for Developmental Biology, Kobe, 650-0047, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"237","reference":[{"key":"2021042606401612900_R1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ydbio.2007.01.045","article-title":"Molecular mechanisms of optic vesicle development: complexities, ambiguities and controversies","volume":"305","author":"Adler","year":"2007","journal-title":"Dev. 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