{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T06:08:36Z","timestamp":1791266916734,"version":"4.1.0"},"reference-count":43,"publisher":"The Company of Biologists","issue":"2","license":[{"start":{"date-parts":[[1988,2,1]],"date-time":"1988-02-01T00:00:00Z","timestamp":570672000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.biologists.com\/user-licence-1-1\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1988,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The expression of nuclear lamins during mouse preimplantation development was studied by immunofluorescence, immunoblotting and immunoprecipitation. Two sera were used, specific either for lamin B or lamins A and C. Both sera gave a positive staining of the nuclear periphery throughout preimplantation development (fertilized eggs to late blastocysts). Immunoblots revealed that the three lamins were present in eggs and blastocysts. However, lamin A from eggs was found to have a higher apparent Mr than lamin A from blastocysts and other mouse cells. Using immunoprecipitation, synthesis of lamin A was detected in eggs while synthesis of lamin B was detected in 8-cell embryos and blastocysts, indicating that at least some of the lamins used during early development do not come from a store in the egg. These results are discussed in relation to the possible role of lamins during cell differentiation.<\/jats:p>","DOI":"10.1242\/dev.102.2.271","type":"journal-article","created":{"date-parts":[[2021,4,26]],"date-time":"2021-04-26T00:36:36Z","timestamp":1619397396000},"page":"271-278","source":"Crossref","is-referenced-by-count":43,"title":["Expression of nuclear lamins during mouse preimplantation development"],"prefix":"10.1242","volume":"102","author":[{"given":"Evelyn","family":"Houliston","sequence":"first","affiliation":[{"name":"1 Centre de G\u00e9n\u00e9tique Mol\u00e9culaire CNRS, 91190 Gif sur Yvette, France"},{"name":"University of Cambridge 2 Department of Anatomy , , Downing Street, Cambridge CB2 3DY, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-No\u00eblle","family":"Guilly","sequence":"additional","affiliation":[{"name":"1 Centre de G\u00e9n\u00e9tique Mol\u00e9culaire CNRS, 91190 Gif sur Yvette, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Claude","family":"Courvalin","sequence":"additional","affiliation":[{"name":"1 Centre de G\u00e9n\u00e9tique Mol\u00e9culaire CNRS, 91190 Gif sur Yvette, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"Maro","sequence":"additional","affiliation":[{"name":"1 Centre de G\u00e9n\u00e9tique Mol\u00e9culaire CNRS, 91190 Gif sur Yvette, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"237","published-online":{"date-parts":[[1988,2,1]]},"reference":[{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"560","DOI":"10.1038\/323560a0","article-title":"The nuclear lamina is a meshwork of intermediate-type filaments","volume":"323","author":"Aebi","year":"1986","journal-title":"Nature, Lond"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/0092-8674(85)90072-8","article-title":"Cell type-specific expression of nuclear lamina proteins during development of Xenopus laevis","volume":"41","author":"Benavente","year":"1985","journal-title":"Cell"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1111\/j.1432-1033.1974.tb03599.x","article-title":"A film detection method for tritium-labelled proteins an nucleic acids in polyacrylamide gels","volume":"46","author":"Bonner","year":"1974","journal-title":"Eur. J. Biochem"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1016\/0003-2697(81)90281-5","article-title":"\u201cWestern-blotting\u201d: electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radio-iodinated protein A","volume":"112","author":"Burnette","year":"1981","journal-title":"Anal. Biochem"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1016\/0092-8674(86)90761-0","article-title":"Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer in a region containing topoisomerase II sites","volume":"44","author":"Cockerill","year":"1986","journal-title":"Cell"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"6450","DOI":"10.1073\/pnas.83.17.6450","article-title":"cDNA sequencing of nuclear lamins A and C reveals primary and secondary structural homology to intermediate filament proteins","volume":"83","author":"Fisher","year":"1986","journal-title":"Proc. natn. Acad. Sci. U.S.A"},{"issue":"Supplement","key":"2023040617240127200_","first-page":"271","article-title":"Maturation promoting factor and cell cycle regulation","volume":"89","author":"Ford","year":"1985","journal-title":"J. Embryol. exp. Morph"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1038\/273149a0","article-title":"Activation of mammalian oocytes by intracellular injection of calcium","volume":"273","author":"Fulton","year":"1978","journal-title":"Nature, Lond"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1016\/0092-8674(86)90877-9","article-title":"Cohabitation of scaffold binding regions with upstream enhancer elements of three developmentally regulated genes of D. melanogaster","volume":"46","author":"Gasser","year":"1986","journal-title":"Cell"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1002\/j.1460-2075.1986.tb04240.x","article-title":"The organization of chromatin loops: characterization of a scaffold attachment site","volume":"5","author":"Gasser","year":"1986","journal-title":"EMBO J"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1016\/0168-9525(87)90156-9","article-title":"A glimpse at chromosomal order","volume":"3","author":"Gasser","year":"1987","journal-title":"TIG"},{"key":"2023040617240127200_","first-page":"443","article-title":"Nuclear lamina and organization of nuclear architecture","volume":"11","author":"Gerace","year":"1986","journal-title":"TIBS"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1016\/0092-8674(80)90409-2","article-title":"The nuclear envelope lamina is reversibly depolymerized during mitosis","volume":"19","author":"Gerace","year":"1980","journal-title":"Cell"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"3839","DOI":"10.1073\/pnas.83.11.3839","article-title":"Keratin-like proteins that coisolate with intermediate filaments of BHK-21 cells are nuclear lamins","volume":"83","author":"Goldman","year":"1986","journal-title":"Proc. natn. Acad. Sci. U.S.A"},{"key":"2023040617240127200_","first-page":"266","article-title":"Autoantibodies to nuclear lamin B in a patient with thrombopenia","volume":"43","author":"Guilly","year":"1987","journal-title":"Eur. J. Cell Biol"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"2569","DOI":"10.1083\/jcb.103.6.2569","article-title":"Topoisomerase II: a specific marker for cell proliferation","volume":"103","author":"Heck","year":"1986","journal-title":"J. Cell Biol"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1016\/0092-8674(86)90324-7","article-title":"A set of proteins showing cell cycle dependent modification in the early mouse embryo","volume":"45","author":"Howlett","year":"1986","journal-title":"Cell"},{"key":"2023040617240127200_","first-page":"175","article-title":"Sequence and regulation of morphological and molecular events during the first cell cycle of mouse embryogenesis","volume":"87","author":"Howlett","year":"1985","journal-title":"J. Embryol. exp. Morph"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"919","DOI":"10.1002\/j.1460-2075.1985.tb03719.x","article-title":"Transcription occurs at a nucleoskeleton","volume":"4","author":"Jackson","year":"1985","journal-title":"EMBO J"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"1403","DOI":"10.1002\/j.1460-2075.1986.tb04374.x","article-title":"Replication occurs at a nucleoskeleton","volume":"5","author":"Jackson","year":"1986","journal-title":"EMBO J"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1016\/S0076-6879(87)51009-6","article-title":"Mouse teratocarcinoma cells","volume":"151","author":"Jakob","year":"1987","journal-title":"Methods in Enzymology"},{"key":"2023040617240127200_","first-page":"35","article-title":"Time and space in the early mouse embryo: a cell biological approach to cell diversification","volume-title":"In Experimental Approaches to Mammalian Embryonic Development","author":"Johnson","year":"1987"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/0168-9525(85)90021-6","article-title":"The timing of early developmental events in Xenopus","volume":"1","author":"Kirschner","year":"1985","journal-title":"TIG"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/0014-4827(86)90421-0","article-title":"The nuclear lamins: a multigene family of proteins in evolution and differentiation","volume":"162","author":"Krohne","year":"1986","journal-title":"Expl Cell Res"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/0022-2836(81)90224-2","article-title":"Cell type-specific differences in protein composition of nuclear pore-lamina structures in oocytes and erythrocytes of Xenopus laevis","volume":"151","author":"Krohne","year":"1981","journal-title":"J. molec. Biol"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"11713","DOI":"10.1038\/227680a0","article-title":"Cleavage of structural proteins during the assembly of the head of bacteriophage T4","volume":"227","author":"Laemmli","year":"1970","journal-title":"Nature, Land"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"13293","DOI":"10.1016\/S0021-9258(18)69303-2","article-title":"The nuclear lamin protein family in higher vertebrates: identification of quantitatively minor lamin proteins by monoclonal antibodies","volume":"261","author":"Lehner","year":"1986","journal-title":"J. biol. Chem"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1016\/0012-1606(78)90066-0","article-title":"Poly(A) and synthesis of polyadenylated RNA in the preimplantation mouse embryo","volume":"64","author":"Levey","year":"1978","journal-title":"Devi Biol"},{"key":"2023040617240127200_","first-page":"211","article-title":"Changes in the actin distribution during fertilisation of the mouse egg","volume":"81","author":"Maro","year":"1984","journal-title":"J. Embryol. exp. Morph"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1038\/319463a0","article-title":"Homologies in both primary and secondary structure between nuclear envelope and intermediate filament protein","volume":"319","author":"Mckeon","year":"1986","journal-title":"Nature, Lond"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"4374","DOI":"10.1073\/pnas.80.14.4374","article-title":"Autoimmune response against conserved determinants of nuclear envelope proteins in a patient with linear sclerodermia","volume":"80","author":"Mckeown","year":"1983","journal-title":"Proc. natn. Acad. Sci. U.S.A"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/0092-8674(84)90208-3","article-title":"Organization of the higher-order chromatin loop: specific DNA attachment sites on nuclear scaffold","volume":"39","author":"Mirkovitch","year":"1984","journal-title":"Cell"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"731","DOI":"10.1016\/0092-8674(84)90409-4","article-title":"Regulation of the cell cycle during early Xenopus development","volume":"37","author":"Newport","year":"1984","journal-title":"Cell"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1083\/jcb.66.2.263","article-title":"Ultrastructural localisation of lectin binding sites on the zonae pellucidae and plasma membranes of mammahan eggs","volume":"66","author":"Nicolson","year":"1975","journal-title":"J. Cell Biol"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"624","DOI":"10.1016\/S0021-9258(18)89778-2","article-title":"Phosphorylation of the nuclear lamins during interphase and mitosis","volume":"260","author":"Ottaviano","year":"1985","journal-title":"J. biol. Chem"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"4727","DOI":"10.1073\/pnas.82.14.4727","article-title":"Nuclear lamins and peripheral nuclear antigens during fertilization and embryogenesis in mice and sea urchins","volume":"82","author":"Schatten","year":"1985","journal-title":"Proc. natn. Acad. Sci. U.S.A"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"1037","DOI":"10.1073\/pnas.78.2.1037","article-title":"Calcium lability of cytoplasmic microtubules and its modulation by microtubule associated proteins","volume":"78","author":"Schliwa","year":"1981","journal-title":"Proc. natn. Acad. Sci. U.S.A"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1083\/jcb.99.1.20","article-title":"Identification, developmental regulation, and response to heat shock to two antigenitically related forms of a major nuclear envelope protein in Drosophila embryos: Application of an improved method for affinity purification of antibodies using polypeptides immobilized on nitrocellulose blots","volume":"99","author":"Smith","year":"1984","journal-title":"J. Cell Biol"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1016\/0092-8674(85)90073-X","article-title":"Changes in the nuclear lamina composition during early development of Xenopus laevis","volume":"41","author":"Stick","year":"1985","journal-title":"Cell"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"4350","DOI":"10.1073\/pnas.76.9.4350","article-title":"Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications","volume":"76","author":"Towbin","year":"1979","journal-title":"Proc. natn. Acad. Sci. U.S.A"},{"key":"2023040617240127200_","first-page":"131","article-title":"Parthenogenesis and cytoskeletal organisation in ageing mouse eggs","volume":"95","author":"Webb","year":"1986","journal-title":"J. Embryol. exp. Morph"},{"key":"2023040617240127200_","doi-asserted-by":"publisher","first-page":"1065","DOI":"10.1071\/BI9691065","article-title":"Storage of two-cell mouse embryos in vitro","volume":"22","author":"Whittingham","year":"1969","journal-title":"Austr. J. biol. Sci"},{"key":"2023040617240127200_","first-page":"133","article-title":"Uridine and guanosine incorporation by the mouse one-cell embryo","volume":"44","author":"Young","year":"1978","journal-title":"J. Embryol. exp. Morph"}],"container-title":["Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.biologists.com\/dev\/article-pdf\/102\/2\/271\/2785892\/develop_102_2_271.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/journals.biologists.com\/dev\/article-pdf\/102\/2\/271\/2785892\/develop_102_2_271.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,6]],"date-time":"2023-04-06T17:27:35Z","timestamp":1680802055000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.biologists.com\/dev\/article\/102\/2\/271\/35895\/Expression-of-nuclear-lamins-during-mouse"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,2,1]]},"references-count":43,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1988,2,1]]}},"URL":"https:\/\/doi.org\/10.1242\/dev.102.2.271","relation":{},"ISSN":["0950-1991","1477-9129"],"issn-type":[{"value":"0950-1991","type":"print"},{"value":"1477-9129","type":"electronic"}],"subject":[],"published":{"date-parts":[[1988,2,1]]}}}