{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T21:10:00Z","timestamp":1791148200839,"version":"4.1.0"},"reference-count":49,"publisher":"The Company of Biologists","issue":"1","license":[{"start":{"date-parts":[[1991,1,9]],"date-time":"1991-01-09T00:00:00Z","timestamp":663379200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.biologists.com\/user-licence-1-1\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1991,1,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>We report here the characterization of restrictin, a novel chick neural extracellular matrix glycoprotein associated with the cell recognition molecule F11. hnmunoaffinity chromatography using monoclonal antibody 23-13 directed to restrictin yield a maior relative .molecular mass band at 170\u00d7103 animmorWas al and 320 \u00d7103 w\u201cich are immunologically related to each other. Neural cells attach on immobilized restrictin in a short-term adhesion assay. This adhesion can be blocked specifically by monoclonal or polyclonal antibodies to restrictin but not by antibodies to Fll or by the peptide GRGDSP. Antibodies to restrictin do not interfere with the fasciculation of retinal axons and the isolated restrictin does not stimulate the outgrowth of axons. In the developing nervous system, restrictin is localized in very restricted regions and is found within areas of Fll expression. The timing and pattern of expression of restrictin and its cell attachment activity suggest that it participates in developmental events of the nervous system.<\/jats:p>","DOI":"10.1242\/dev.113.1.151","type":"journal-article","created":{"date-parts":[[2021,4,23]],"date-time":"2021-04-23T18:25:16Z","timestamp":1619202316000},"page":"151-164","source":"Crossref","is-referenced-by-count":113,"title":["Restrictin: a chick neural extracellular matrix protein involved in cell attachment co-purifies with the cell recognition molecule F11"],"prefix":"10.1242","volume":"113","author":[{"given":"Fritz","family":"G. Rathjen","sequence":"first","affiliation":[{"name":"1 Zentrum fur Molekulare Neurobiologie, Martinistrasse 52, D-2000 Hamburg 20, FRG"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Wolff","sequence":"additional","affiliation":[{"name":"2 Max-Planck-Institut fur Entwicklungsbiologie, D-7400 Tubingen, FRG"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth","family":"Chiquet-Ehrismann","sequence":"additional","affiliation":[{"name":"3 Friedrich-Miescher-Institut, CH-4002 Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"237","published-online":{"date-parts":[[1991,1,9]]},"reference":[{"key":"2024022603234745000_DEVELOP_113_1_151C1","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/0165-022X(85)90037-5","article-title":"Fast and sensitive detection of protein and DNA bands by treatment with potassium permanganate","volume":"11","author":"Ansorge","year":"1985","journal-title":"J. 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