{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T18:05:33Z","timestamp":1791396333823,"version":"4.3.3"},"reference-count":71,"publisher":"The Company of Biologists","issue":"1","license":[{"start":{"date-parts":[[1996,12,1]],"date-time":"1996-12-01T00:00:00Z","timestamp":849398400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.biologists.com\/user-licence-1-1\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1996,12,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>In a large scale screen for genetic defects in zebrafish embryogenesis we identified 49 mutations affecting development of the retina. Based on analysis of living embryos as well as histological sections, we grouped the isolated mutations into six phenotypic categories. (1) Mutations in three loci result in a loss of wild-type laminar pattern of the neural retina. (2) Defects in four loci lead to an abnormal specification of the eye anlagen. Only one eye frequently forms in this class of mutants. (3) Seven loci predominantly affect development of the outer retinal layers. Mutants in this category display cell loss mainly in the photoreceptor cell layer. (4) Nine mutations cause retardation of eye growth without any other obvious abnormalities in the retina. (5) A group of twelve mutations is characterized by nonspecific retinal degeneration. (6) Four mutations display retinal degeneration associated with a pigmentation defect. Finally, two mutations, one with absence of the ventral retina and one with an eye-specific pigmentation defect, are not classified in any of the above groups. The identified mutations affect numerous aspects of eye development, including: specification of the eye anlage, growth rate of the optic cup, establishment of retinal stratification, specification or differentiation of retinal neurons and formation of the dorsoventral axis in the developing eye.<\/jats:p>","DOI":"10.1242\/dev.123.1.263","type":"journal-article","created":{"date-parts":[[2021,4,25]],"date-time":"2021-04-25T22:50:37Z","timestamp":1619391037000},"page":"263-273","source":"Crossref","is-referenced-by-count":229,"title":["Mutations affecting development of the zebrafish retina"],"prefix":"10.1242","volume":"123","author":[{"given":"Jarema","family":"Malicki","sequence":"first","affiliation":[{"name":"Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, 13 th Street, Building 149, Charlestown, MA 02129, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan C. F.","family":"Neuhauss","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, 13 th Street, Building 149, Charlestown, MA 02129, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander F.","family":"Schier","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, 13 th Street, Building 149, Charlestown, MA 02129, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lilianna","family":"Solnica-Krezel","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, 13 th Street, Building 149, Charlestown, MA 02129, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derek L.","family":"Stemple","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, 13 th Street, Building 149, Charlestown, MA 02129, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didier Y. R","family":"Stainier","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, 13 th Street, Building 149, Charlestown, MA 02129, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salim","family":"Abdelilah","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, 13 th Street, Building 149, Charlestown, MA 02129, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fried","family":"Zwartkruis","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, 13 th Street, Building 149, Charlestown, MA 02129, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zehava","family":"Rangini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"Driever","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"237","published-online":{"date-parts":[[1996,12,1]]},"reference":[{"key":"2023072810030599200_DEVELOP_123_1_263C1","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1242\/dev.123.1.217","article-title":"Mutations affecting neural survival in the zebrafish, Danio rerio","volume":"123","author":"Abdelilah","year":"1996","journal-title":"Development"},{"key":"2023072810030599200_DEVELOP_123_1_263C2","doi-asserted-by":"publisher","first-page":"1317","DOI":"10.1242\/dev.119.4.1317","article-title":"Taurine promotes the differentiation of a vertebrate retinal cell type in vitro","volume":"119","author":"Altshuler","year":"1993","journal-title":"Development"},{"key":"2023072810030599200_DEVELOP_123_1_263C3","first-page":"37","article-title":"Specification of cell type in the vertebrate retina","volume-title":"In Development of the Visual System","author":"Altshuler","year":"1991"},{"key":"2023072810030599200_DEVELOP_123_1_263C4","doi-asserted-by":"publisher","first-page":"1370","DOI":"10.1126\/science.2175046","article-title":"Spacing differentiation in the developing Drosophila eye: a fibrinogen-related lateral inhibitor encoded by scabrous","volume":"250","author":"Baker","year":"1990","journal-title":"Science"},{"key":"2023072810030599200_DEVELOP_123_1_263C5","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1038\/347677a0","article-title":"Retinal degeneration in the rd mouse is caused by a defect in the beta subunit of rod cGMP-phosphodiesterase","volume":"347","author":"Bowes","year":"1990","journal-title":"Nature"},{"key":"2023072810030599200_DEVELOP_123_1_263C6","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1002\/cne.902240109","article-title":"The Development of Photoreceptors in the Zebrafish, Brachydanio rerio. I. Structure","volume":"224","author":"Branchek","year":"1984","journal-title":"J. Comp. Neurol"},{"key":"2023072810030599200_DEVELOP_123_1_263C7","doi-asserted-by":"publisher","first-page":"10545","DOI":"10.1073\/pnas.92.23.10545","article-title":"A behavioral screen for isolating zebrafish mutants with visual system defects","volume":"92","author":"Brockerhoff","year":"1995","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2023072810030599200_DEVELOP_123_1_263C8","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1016\/0092-8674(95)90291-0","article-title":"Hairy and emc negatively regulate morphogenetic furrow progression in the Drosophila eye","volume":"80","author":"Brown","year":"1995","journal-title":"Cell"},{"key":"2023072810030599200_DEVELOP_123_1_263C9","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1146\/annurev.ne.01.030178.001501","article-title":"Mechanisms of cortical development: a view from mutations in mice","volume":"1","author":"Caviness","year":"1978","journal-title":"Ann. Rev. Neurosci"},{"key":"2023072810030599200_DEVELOP_123_1_263C10","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1093\/genetics\/103.1.109","article-title":"Frequency of gamma-ray induced specific locus and recessive lethal mutations in mature germ cells of the zebrafish, Brachydanio rerio","volume":"103","author":"Chakrabarti","year":"1983","journal-title":"Genetics"},{"key":"2023072810030599200_DEVELOP_123_1_263C11","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1016\/0896-6273(93)90072-Y","article-title":"Apoptosis: final common pathway of photoreceptor death in rd, rds, and rhodopsin mutant mice","volume":"11","author":"Chang","year":"1993","journal-title":"Neuron"},{"key":"2023072810030599200_DEVELOP_123_1_263C12","doi-asserted-by":"publisher","first-page":"977","DOI":"10.1016\/0896-6273(94)90308-5","article-title":"The Drosophila sine oculis locus encodes a homeodomain-containing protein required for the development of the entire visual system","volume":"12","author":"Cheyette","year":"1994","journal-title":"Neuron"},{"key":"2023072810030599200_DEVELOP_123_1_263C13","volume-title":"Visual responses in developing zebrafish (Brachydanio rerio)","author":"Clark","year":"1981"},{"key":"2023072810030599200_DEVELOP_123_1_263C14","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1038\/324459a0","article-title":"A cell surface molecule distributed in a dorsoventral gradient in the perinatal rat retina","volume":"324","author":"Constantine-Paton","year":"1986","journal-title":"Nature"},{"key":"2023072810030599200_DEVELOP_123_1_263C15","doi-asserted-by":"publisher","first-page":"719","DOI":"10.1038\/374719a0","article-title":"A protein related to extracellular matrix proteins deleted in the mouse mutant reeler","volume":"374","author":"D\u2019Arcangelo","year":"1995","journal-title":"Nature"},{"key":"2023072810030599200_DEVELOP_123_1_263C16","doi-asserted-by":"publisher","first-page":"1333","DOI":"10.1242\/dev.117.4.1333","article-title":"Isolation and characterization of murine homologues of the Drosophila seven in absentia gene","volume":"117","author":"Della","year":"1993","journal-title":"Development"},{"key":"2023072810030599200_DEVELOP_123_1_263C17","volume-title":"The Retina","author":"Dowling","year":"1987"},{"key":"2023072810030599200_DEVELOP_123_1_263C18","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1242\/dev.123.1.37","article-title":"A genetic screen for mutations affecting embryogenesis in zebrafish","volume":"123","author":"Driever","year":"1996","journal-title":"Development"},{"key":"2023072810030599200_DEVELOP_123_1_263C19","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1038\/343364a0","article-title":"A point mutation of the rhodopsin gene in patients with autosomal dominant retinitis pigmentosa","volume":"343","author":"Dryja","year":"1990","journal-title":"Nature"},{"key":"2023072810030599200_DEVELOP_123_1_263C20","first-page":"1197","article-title":"Retinitis pigmentosa and allied diseases. Implications of genetic heterogeneity","volume":"36","author":"Dryja","year":"1995","journal-title":"Invest. Ophthal. Vis. Sci"},{"key":"2023072810030599200_DEVELOP_123_1_263C21","doi-asserted-by":"publisher","first-page":"1403","DOI":"10.1002\/j.1460-2075.1993.tb05784.x","article-title":"Functional conservation of vertebrate seven-up related genes in neurogenesis and eye development","volume":"12","author":"Fjose","year":"1993","journal-title":"EMBO"},{"key":"2023072810030599200_DEVELOP_123_1_263C22","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1126\/science.8469990","article-title":"Neuronal differentiation rescued by implantation of weaver granule cell precursors into wild-type cerebellar cortex","volume":"260","author":"Gao","year":"1993","journal-title":"Science"},{"key":"2023072810030599200_DEVELOP_123_1_263C23","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1016\/0092-8674(92)90028-B","article-title":"The weaver gene encodes a nonautonomous signal for CNS neuronal differentiation","volume":"68","author":"Gao","year":"1992","journal-title":"Cell"},{"key":"2023072810030599200_DEVELOP_123_1_263C24","first-page":"12","article-title":"Catalog of mutant genes and polymorphic loci","volume-title":"In Genetic Variants and Strains of the Laboratory Mouse","author":"Green","year":"1990"},{"key":"2023072810030599200_DEVELOP_123_1_263C25","doi-asserted-by":"publisher","first-page":"913","DOI":"10.1016\/0092-8674(93)90535-X","article-title":"The TGF homolog dpp and the segment polarity gene hedgehog are required for propagation of a morphogenetic wave in the Drosophila retina","volume":"75","author":"Haberlein","year":"1993","journal-title":"Cell"},{"key":"2023072810030599200_DEVELOP_123_1_263C26","doi-asserted-by":"publisher","first-page":"1788","DOI":"10.1126\/science.7892602","article-title":"Induction of ectopic eyes by targeted expression of the eyeless gene in Drosophila","volume":"267","author":"Halder","year":"1995","journal-title":"Science"},{"key":"2023072810030599200_DEVELOP_123_1_263C27","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1016\/0896-6273(92)90027-B","article-title":"Role of the floor plate in axonal patterning in the zebrafish CNS","volume":"9","author":"Hatta","year":"1992","journal-title":"Neuron"},{"key":"2023072810030599200_DEVELOP_123_1_263C28","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1038\/350339a0","article-title":"The cyclops mutation blocks specification of the floor plate of the zebrafish central nervous system","volume":"350","author":"Hatta","year":"1991","journal-title":"Nature"},{"key":"2023072810030599200_DEVELOP_123_1_263C29","first-page":"220","article-title":"Neue Mutationen und Kopplungsgruppen bei der Hausmaus","volume":"80","author":"Hertwig","year":"1942","journal-title":"Z. Indukt. Abstammungs-Vererbungsl"},{"key":"2023072810030599200_DEVELOP_123_1_263C30","doi-asserted-by":"publisher","first-page":"522","DOI":"10.1038\/354522a0","article-title":"Mouse Small eye results from mutations in a paired-like homeobox-containing gene","volume":"354","author":"Hill","year":"1991","journal-title":"Nature"},{"key":"2023072810030599200_DEVELOP_123_1_263C31","doi-asserted-by":"publisher","first-page":"728","DOI":"10.1038\/348728a0","article-title":"Cell-autonomous action of zebrafish spt-1 mutation in specific mesodermal precursors","volume":"348","author":"Ho","year":"1990","journal-title":"Nature"},{"key":"2023072810030599200_DEVELOP_123_1_263C32","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1016\/0092-8674(93)90429-T","article-title":"Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein","volume":"74","author":"Hodgkinson","year":"1993","journal-title":"Cell"},{"key":"2023072810030599200_DEVELOP_123_1_263C33","first-page":"95","article-title":"Small eyes (Sey): a homozygous lethal mutation on chromosome 2 which affects the differentiation of both lens nad nasal placodes in the mouse","volume":"97","author":"Hogan","year":"1986","journal-title":"J. Embryol. Exp. Morph"},{"key":"2023072810030599200_DEVELOP_123_1_263C34","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1002\/jez.1401890309","article-title":"Pigmented retinal epithelium involvement in photoreceptor development and function","volume":"189","author":"Hollyfield","year":"1974","journal-title":"J. Exp. Zool"},{"key":"2023072810030599200_DEVELOP_123_1_263C35","doi-asserted-by":"publisher","first-page":"9","DOI":"10.3109\/10520297409116929","article-title":"A simple methylene blue-azure II-basic fuchsin stain for epoxy-embedded tissue sections","volume":"49","author":"Humphrey","year":"1974","journal-title":"Stain Technol"},{"key":"2023072810030599200_DEVELOP_123_1_263C36","doi-asserted-by":"crossref","DOI":"10.1007\/978-1-4757-4954-0","article-title":"Developmental Neurobiology","author":"Jacobson","year":"1991"},{"key":"2023072810030599200_DEVELOP_123_1_263C37","doi-asserted-by":"publisher","first-page":"1604","DOI":"10.1126\/science.8202715","article-title":"Digenic retinitis pigmentosa due to mutations at the unlinked peripherin\/RDS and ROM1 loci","volume":"264","author":"Kajiwara","year":"1994","journal-title":"Science"},{"key":"2023072810030599200_DEVELOP_123_1_263C38","doi-asserted-by":"publisher","first-page":"2091","DOI":"10.1242\/dev.120.8.2091","article-title":"Retinoic acid promotes differentiation of photoreceptors in vitro","volume":"120","author":"Kelley","year":"1994","journal-title":"Development"},{"key":"2023072810030599200_DEVELOP_123_1_263C39","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1002\/aja.1002030302","article-title":"Stages of embryonic development of the zebrafish","volume":"203","author":"Kimmel","year":"1995","journal-title":"Dev. Dyn"},{"key":"2023072810030599200_DEVELOP_123_1_263C40","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1242\/dev.123.1.451","article-title":"A reference cross DNA panel for zebrafish (Danio rerio) anchored with simple sequence length polymorphisms","volume":"123","author":"Knapik","year":"1996","journal-title":"Development"},{"key":"2023072810030599200_DEVELOP_123_1_263C41","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/0012-1606(76)90282-7","article-title":"The cell cycle and retinal histogenesis in fidget mutant mice","volume":"54","author":"Konyukhov","year":"1976","journal-title":"Dev. Biol"},{"key":"2023072810030599200_DEVELOP_123_1_263C42","doi-asserted-by":"publisher","first-page":"1299","DOI":"10.1523\/JNEUROSCI.10-04-01299.1990","article-title":"Pathfinding by identified growth cones in the spinal cord of zebrafish embryos","volume":"10","author":"Kuwada","year":"1990","journal-title":"J. Neurosci"},{"key":"2023072810030599200_DEVELOP_123_1_263C43","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1242\/dev.109.3.567","article-title":"Early onset of phenotype and cell patterning in the embryonic zebrafish retina","volume":"109","author":"Larison","year":"1990","journal-title":"Development"},{"key":"2023072810030599200_DEVELOP_123_1_263C44","doi-asserted-by":"publisher","first-page":"927","DOI":"10.1016\/0092-8674(93)90536-Y","article-title":"The segment polarity gene hedgehog is required for progression of the morphogenetic furrow in the developing Drosophila eye","volume":"75","author":"Ma","year":"1993","journal-title":"Cell"},{"key":"2023072810030599200_DEVELOP_123_1_263C45","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1242\/dev.123.1.275","article-title":"Mutations affecting development of the zebrafish ear","volume":"123","author":"Malicki","year":"1996","journal-title":"Development"},{"key":"2023072810030599200_DEVELOP_123_1_263C46","doi-asserted-by":"publisher","first-page":"7286","DOI":"10.1073\/pnas.91.15.7286","article-title":"Retinoic acid is necessary for development of the ventral retina in zebrafish","volume":"91","author":"Marsh-Armstrong","year":"1994","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2023072810030599200_DEVELOP_123_1_263C47","doi-asserted-by":"publisher","first-page":"698","DOI":"10.1242\/dev.112.3.693","article-title":"Aldehyde dehydrogenase is a positional marker in the retina","volume":"112","author":"McCaffery","year":"1991","journal-title":"Development"},{"key":"2023072810030599200_DEVELOP_123_1_263C48","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1038\/ng0693-130","article-title":"Recessive mutations in the gene encoding the beta-subunit of rod phosphodiesterase in patients with retinitis pigmentosa","volume":"4","author":"McLaughlin","year":"1993","journal-title":"Nature Genetics"},{"key":"2023072810030599200_DEVELOP_123_1_263C49","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/S0960-9822(00)00048-8","article-title":"Large-scale mutagenesis in the zebrafish: in search of genes controlling development in vertebrate","volume":"4","author":"Mullins","year":"1994","journal-title":"Curr. Biol"},{"key":"2023072810030599200_DEVELOP_123_1_263C50","volume-title":"Development of the neural retina in the zebrafish, Brachydanio rerio","author":"Nawrocki","year":"1985"},{"key":"2023072810030599200_DEVELOP_123_1_263C51","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1016\/0092-8674(95)90508-1","article-title":"cAMP-dependent protein kinase and hedgehog act antagonisticall in regulating decapentaplegic transcription in Drosophila imaginal discs","volume":"80","author":"Pan","year":"1995","journal-title":"Cell"},{"key":"2023072810030599200_DEVELOP_123_1_263C52","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1242\/dev.113.2.577","article-title":"Basic fibroblast growth factor induces retinal pigment epithelium to generate neural retina","volume":"113","author":"Pittack","year":"1991","journal-title":"Development"},{"key":"2023072810030599200_DEVELOP_123_1_263C53","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1126\/science.7914031","article-title":"Homology of the eyeless gene of Drosophila to the Small eye gene in mice and Aniridia in humans","volume":"265","author":"Quiring","year":"1994","journal-title":"Science"},{"key":"2023072810030599200_DEVELOP_123_1_263C54","first-page":"59","article-title":"Cell determination and positional clues in the teleost retina: development of photoreceptors and horizontal cells","volume-title":"In Development of the Visual System","author":"Raymond","year":"1991"},{"key":"2023072810030599200_DEVELOP_123_1_263C55","doi-asserted-by":"publisher","first-page":"1161","DOI":"10.1016\/0896-6273(93)90064-X","article-title":"Expression of rod and cone visual pPigments in godfish and zebrafish: a rhodopsin-like gene is expressed in cones","volume":"10","author":"Raymond","year":"1993","journal-title":"Neuron"},{"key":"2023072810030599200_DEVELOP_123_1_263C56","doi-asserted-by":"publisher","first-page":"596","DOI":"10.1002\/cne.903450409","article-title":"The development of GABA immunoreactivity in the retina of the zebrafish","volume":"345","author":"Sandell","year":"1994","journal-title":"J. Comp. Neurol"},{"key":"2023072810030599200_DEVELOP_123_1_263C57","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1242\/dev.123.1.165","article-title":"Mutations affecting the development of the embryonic zebrafish brain","volume":"123","author":"Schier","year":"1996","journal-title":"Development"},{"key":"2023072810030599200_DEVELOP_123_1_263C58","doi-asserted-by":"publisher","first-page":"532","DOI":"10.1002\/cne.903440404","article-title":"Early eye morphogenesis in the zebrafish, Brachydanio rerio","volume":"344","author":"Schmitt","year":"1994","journal-title":"J. Comp. Neurol"},{"key":"2023072810030599200_DEVELOP_123_1_263C59","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1016\/0012-1606(79)90252-5","article-title":"Studies on the development of the eye cup on optic nerve in normal mice and in mutants with congenital optic nerve aplasia","volume":"68","author":"Silver","year":"1979","journal-title":"Dev. Biol"},{"key":"2023072810030599200_DEVELOP_123_1_263C60","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1016\/0092-8674(91)90065-7","article-title":"Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase","volume":"67","author":"Simon","year":"1991","journal-title":"Cell"},{"key":"2023072810030599200_DEVELOP_123_1_263C61","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1093\/genetics\/136.4.1401","article-title":"Efficient recovery of ENU-induced mutations from the zebrafish germline","volume":"136","author":"Solnica-Krezel","year":"1994","journal-title":"Genetics"},{"key":"2023072810030599200_DEVELOP_123_1_263C62","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1242\/dev.123.1.67","article-title":"Mutations affecting cell fates and cellular rearrangements during gastrulation in zebrafish","volume":"123","author":"Solnica-Krezel","year":"1996","journal-title":"Development"},{"key":"2023072810030599200_DEVELOP_123_1_263C63","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1242\/dev.123.1.285","article-title":"Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo","volume":"123","author":"Stainier","year":"1996","journal-title":"Development"},{"key":"2023072810030599200_DEVELOP_123_1_263C64","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1038\/ng1194-251","article-title":"Waardenburg syndrome type 2 caused by mutations in the human microphthalmia (MITF) gene","volume":"8","author":"Tassabehji","year":"1994","journal-title":"Nature Genetics"},{"key":"2023072810030599200_DEVELOP_123_1_263C65","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1016\/0092-8674(88)90133-X","article-title":"rough, a Drosophila homeobox gene required in photoreceptors R2 and R5 for inductive interactions in the developing eye","volume":"55","author":"Tomlinson","year":"1988","journal-title":"Cell"},{"key":"2023072810030599200_DEVELOP_123_1_263C66","doi-asserted-by":"publisher","first-page":"669","DOI":"10.1016\/0896-6273(90)90194-K","article-title":"Organisation of hindbrain segments in the zebrafish embryo","volume":"4","author":"Trevarrow","year":"1990","journal-title":"Neuron"},{"key":"2023072810030599200_DEVELOP_123_1_263C67","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1007\/BF02981704","article-title":"The anatomy and development of the fidget mouse","volume":"54","author":"Truslove","year":"1956","journal-title":"J. Genet"},{"key":"2023072810030599200_DEVELOP_123_1_263C68","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1016\/0896-6273(90)90058-N","article-title":"Rod photoreceptor development in vitro: intrinsic properties of proliferating neuroepithelial cells change as development proceeds in the rat retina","volume":"2","author":"Watanabe","year":"1990","journal-title":"Neuron"},{"key":"2023072810030599200_DEVELOP_123_1_263C69","volume-title":"The Zebrafish Book","author":"Westerfield","year":"1994"},{"key":"2023072810030599200_DEVELOP_123_1_263C70","doi-asserted-by":"publisher","first-page":"1223","DOI":"10.1242\/dev.117.4.1223","article-title":"Analysis of genetic mosaics in developing and adult Drosophila tissues","volume":"117","author":"Xu","year":"1993","journal-title":"Development"},{"key":"2023072810030599200_DEVELOP_123_1_263C71","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1146\/annurev.ne.17.030194.002105","article-title":"Determination of neuronal cell fate: lessons from the R7 neuron of Drosophila","volume":"17","author":"Zipursky","year":"1994","journal-title":"Ann. Rev. Neurosci"}],"container-title":["Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.biologists.com\/dev\/article-pdf\/123\/1\/263\/3084409\/develop_123_1_263.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/journals.biologists.com\/dev\/article-pdf\/123\/1\/263\/3084409\/develop_123_1_263.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,28]],"date-time":"2023-07-28T06:04:31Z","timestamp":1690524271000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.biologists.com\/dev\/article\/123\/1\/263\/39331\/Mutations-affecting-development-of-the-zebrafish"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,12,1]]},"references-count":71,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1996,12,1]]}},"URL":"https:\/\/doi.org\/10.1242\/dev.123.1.263","relation":{},"ISSN":["0950-1991","1477-9129"],"issn-type":[{"value":"0950-1991","type":"print"},{"value":"1477-9129","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,12,1]]}}}