{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T04:11:46Z","timestamp":1791087106020,"version":"4.1.0"},"reference-count":136,"publisher":"The Company of Biologists","issue":"2","license":[{"start":{"date-parts":[[1997,1,15]],"date-time":"1997-01-15T00:00:00Z","timestamp":853286400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.biologists.com\/user-licence-1-1\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1997,1,15]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>The zebrafish locus one-eyed pinhead (oep) is essential for the formation of anterior axial mesoderm, endoderm and ventral neuroectoderm. At the beginning of gastrulation anterior axial mesoderm cells form the prechordal plate and express goosecoid (gsc) in wild-type embryos. In oep mutants the prechordal plate does not form and gsc expression is not maintained. Exposure to lithium, a dorsalizing agent, leads to the ectopic induction and maintenance of gsc expression in wild-type embryos. Lithium treatment of oep mutants still leads to ectopic gsc induction but not maintenance, suggesting that oep acts downstream of inducers of dorsal mesoderm. In genetic mosaics, wild-type cells are capable of forming anterior axial mesoderm in oep embryos, suggesting that oep is required in prospective anterior axial mesoderm cells before gastrulation.<\/jats:p>\n               <jats:p>The oep gene is also essential for endoderm formation and the early development of ventral neuroectoderm, including the floor plate. The loss of endoderm is already manifest during gastrulation by the absence of axial-expressing cells in the hypoblast of oep mutants. These findings suggest that oep is also required in lateral and ventral regions of the gastrula margin. The sonic hedgehog (shh).gene is expressed in the notochord of oep animals. Therefore, the impaired floor plate development in oep mutants is not caused by the absence of the floor plate inducer shh. This suggests that oep is required down-stream or in parallel to shh signaling. The ventral region of the forebrain is also absent in oep mutants, leading to severe cyclopia. In contrast, anterior-posterior brain patterning appears largely unaffected, suggesting that underlying prechordal plate is not required for anterior-posterior pattern formation but might be involved in dorsoventral brain patterning.<\/jats:p>\n               <jats:p>To test if oep has a wider, partially redundant role, we constructed double mutants with two other zebrafish loci essential for patterning during gastrulation. Double mutants with floating head, the zebrafish Xnot homologue, display enhanced floor plate and adaxial muscle phenotypes. Double mutants with no tail (ntl), the zebrafish homologue of the mouse Brachyury locus, display severe defects in midline and mesoderm formation including absence of most of the somitic mesoderm. These results reveal a redundant function of oep and ntl in mesoderm formation. Our data suggest that both oep and ntl act in the blastoderm margin to specify mesendodermal cell fates.<\/jats:p>","DOI":"10.1242\/dev.124.2.327","type":"journal-article","created":{"date-parts":[[2021,4,26]],"date-time":"2021-04-26T03:02:39Z","timestamp":1619406159000},"page":"327-342","source":"Crossref","is-referenced-by-count":323,"title":["The <i>one-eyed pinhead<\/i> gene functions in mesoderm and endoderm formation in zebrafish and interacts with <i>no tail<\/i>"],"prefix":"10.1242","volume":"124","author":[{"given":"Alexander F.","family":"Schier","sequence":"first","affiliation":[{"name":"1 Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan C. F.","family":"Neuhauss","sequence":"additional","affiliation":[{"name":"1 Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn Ann","family":"Helde","sequence":"additional","affiliation":[{"name":"University of Utah 2 Department of Human Genetics , , Salt Lake City, UT 84112, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William S.","family":"Talbot","sequence":"additional","affiliation":[{"name":"University of Oregon 3 Institute of Neuroscience , , Eugene, OR 97403, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"Driever","sequence":"additional","affiliation":[{"name":"1 Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"237","published-online":{"date-parts":[[1997,1,15]]},"reference":[{"key":"2025021400183167700_DEVELOP_124_2_327C1","doi-asserted-by":"publisher","first-page":"3279","DOI":"10.1242\/dev.121.10.3279","article-title":"Forebrain and midbrain regions are deleted in Otx2\u2212 \u2212 mutants due to a defective anterior neuroectoderm specification during gastrulation","volume":"121","author":"Acampora","year":"1995","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1002\/jmor.1050540102","article-title":"The development of the prechordal plate and mesoderm of Amblystoma punctatum","volume":"54","author":"Adelmann","year":"1932","journal-title":"J. Morph"},{"key":"2025021400183167700_DEVELOP_124_2_327C3","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1086\/394509","article-title":"The problem of cyclopia. Part II","volume":"11","author":"Adelmann","year":"1936","journal-title":"Q. Rev. Biol"},{"key":"2025021400183167700_DEVELOP_124_2_327C4","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1242\/dev.122.1.243","article-title":"A targeted mouse otx2 mutation leads to severe defects in gastrulation and formation of axial mesoderm and to deletion of rostral brain","volume":"122","author":"Ang","year":"1996","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C5","doi-asserted-by":"publisher","first-page":"2979","DOI":"10.1242\/dev.120.10.2979","article-title":"Positive and negative signals from mesoderm regulate the expression of mouse Otx2 in ectoderm explants","volume":"120","author":"Ang","year":"1994","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C6","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1242\/dev.118.1.139","article-title":"Anterior mesendoderm induces mouse Engrailed genes in explant cultures","volume":"118","author":"Ang","year":"1993","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C7","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1016\/0092-8674(94)90522-3","article-title":"HNF-3 beta is essential for node and notochord formation in mouse development","volume":"78","author":"Ang","year":"1994","journal-title":"Cell"},{"key":"2025021400183167700_DEVELOP_124_2_327C8","doi-asserted-by":"publisher","first-page":"1301","DOI":"10.1242\/dev.119.4.1301","article-title":"The formation and maintenance of the definitive endoderm lineage in the mouse: involvement of HNF3\/forkhead proteins","volume":"119","author":"Ang","year":"1993","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C9","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/0925-4773(91)90050-G","article-title":"The vegetalizing factor from chicken embryos: Its EDF (activin A)-like activity","volume":"34","author":"Asashima","year":"1991","journal-title":"Mech. Dev"},{"key":"2025021400183167700_DEVELOP_124_2_327C10","doi-asserted-by":"publisher","first-page":"1755","DOI":"10.1242\/dev.121.6.1755","article-title":"Expression of zebrafish nk2.2 is influenced by sonic hedgehog\/vertebrate hedgehog-1 and demarcates a zone of neuronal differentiation in the embryonic forebrain","volume":"121","author":"Barth","year":"1995","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C11","first-page":"157","article-title":"Brachyury - a gene affecting mouse gastrulation and early organogenesis","volume-title":"Development","author":"Beddington","year":"1992"},{"key":"2025021400183167700_DEVELOP_124_2_327C12","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1126\/science.1677215","article-title":"Organizer-specific homeobox genes in Xenopus laevis embryos","volume":"253","author":"Blumberg","year":"1991","journal-title":"Science"},{"key":"2025021400183167700_DEVELOP_124_2_327C13","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1093\/genetics\/103.1.109","article-title":"Frequency of ?-ray induced specific locus and recessive lethal mutations in mature germ cells of the zebrafish, Brachydanio rerio","volume":"103","author":"Chakrabarti","year":"1983","journal-title":"Genetics"},{"key":"2025021400183167700_DEVELOP_124_2_327C14","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1002\/jez.1400700306","article-title":"Development of the short-tailed mutation in the house mouse","volume":"70","author":"Chesley","year":"1935","journal-title":"J. Exp. Zool"},{"key":"2025021400183167700_DEVELOP_124_2_327C15","volume-title":"Molecular nature of Spemann\u2019s organizer: the role of the Xenopus","author":"Cho","year":"1991"},{"key":"2025021400183167700_DEVELOP_124_2_327C16","first-page":"183","article-title":"Induction of anteroposterior neural pattern in Xenopus by planar signals","volume-title":"Development","author":"Doniach","year":"1992"},{"key":"2025021400183167700_DEVELOP_124_2_327C17","doi-asserted-by":"publisher","first-page":"1067","DOI":"10.1016\/0092-8674(95)90133-7","article-title":"Basic FGF as an inducer of anteroposterior neural pattern","volume":"83","author":"Doniach","year":"1995","journal-title":"Cell"},{"key":"2025021400183167700_DEVELOP_124_2_327C18","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1242\/dev.123.1.37","article-title":"A genetic screen for mutations affecting embryogenesis in zebrafish","volume":"123","author":"Driever","year":"1996","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C19","doi-asserted-by":"publisher","first-page":"1417","DOI":"10.1016\/0092-8674(93)90627-3","article-title":"Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity","volume":"75","author":"Echelard","year":"1993","journal-title":"Cell"},{"key":"2025021400183167700_DEVELOP_124_2_327C20","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1242\/dev.120.1.71","article-title":"Expression of the zebrafish gene hlx-1 in the prechordal plate and during CNS development","volume":"120","author":"Fjose","year":"1994","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C21","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1006\/dbio.1995.1275","article-title":"Autonomous endodermal determination in Xenopus: regulation of expression of the pancreatic gene XlHbox 8","volume":"171","author":"Gamer","year":"1995","journal-title":"Dev. Biol"},{"key":"2025021400183167700_DEVELOP_124_2_327C22","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1242\/dev.107.Supplement.37","article-title":"Cortical rotation of the Xenopus egg: consequences for the anteroposterior pattern of embryonic dorsal development","volume":"107","author":"Gerhart","year":"1989","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C23","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1073\/pnas.30.6.134","article-title":"The development of normal and homozygous Brachyury (T\/T) mouse embryos in the extraembryonic coelom of the chick","volume":"30","author":"Gluecksohn-Schoenheimer","year":"1944","journal-title":"Proc. Nat. Acad. Sci. USA"},{"key":"2025021400183167700_DEVELOP_124_2_327C24","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1111\/j.1432-0436.1987.tb00146.x","article-title":"Differentiation of cartilage from cranial neural crest in the axolotl (Amblystoma mexicanum)","volume":"35","author":"Graveson","year":"1987","journal-title":"Differentiation"},{"key":"2025021400183167700_DEVELOP_124_2_327C25","first-page":"424","article-title":"Genetic studies on the skeleton of the mouse. XXIII. The development of Brachyury and Anury","volume":"6","author":"Grueneberg","year":"1958","journal-title":"J. Embryol. Exp. Morph"},{"key":"2025021400183167700_DEVELOP_124_2_327C26","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/S0092-8674(05)80087-X","article-title":"Induction of muscle pioneers and floor plate is distinguished by the zebrafish no tail mutation","volume":"75","author":"Halpern","year":"1993","journal-title":"Cell"},{"key":"2025021400183167700_DEVELOP_124_2_327C27","doi-asserted-by":"publisher","first-page":"4257","DOI":"10.1242\/dev.121.12.4257","article-title":"Cell-autonomous shift from axial to paraxial mesodermal development in zebrafish floating head mutants","volume":"121","author":"Halpern","year":"1995","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C28","first-page":"1111","article-title":"The Heritage of Experimental Embryology. Hans homeobox gene goosecoid","volume":"67","author":"Hamburger","year":"1988","journal-title":"Cell"},{"key":"2025021400183167700_DEVELOP_124_2_327C29","volume-title":"Wis Spemann and the Organizer"},{"key":"2025021400183167700_DEVELOP_124_2_327C30","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1016\/0925-4773(94)00318-H","article-title":"Effects of the T mutation on notochord formation and mesodermal patterning","volume":"49","author":"Conlon","year":"1995","journal-title":"Mechanisms of Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C31","doi-asserted-by":"publisher","first-page":"2429","DOI":"10.1242\/dev.121.8.2429","article-title":"FGF is a prospective competence factor for early activin-type signals in Xenopus mesoderm induction","volume":"121","author":"Cornell","year":"1995","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C32","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1038\/358427a0","article-title":"Ectopic mesoderm formation in Xenopus embryos caused by widespread expression of a Brachyury homologue","volume":"358","author":"Cunliffe","year":"1992","journal-title":"Nature"},{"key":"2025021400183167700_DEVELOP_124_2_327C33","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1002\/j.1460-2075.1994.tb06268.x","article-title":"Specification of mesodermal pattern in Xenopus laevis by interactions between Brachyury, noggin and Xwnt-8","volume":"13","author":"Cunliffe","year":"1994","journal-title":"EMBO"},{"key":"2025021400183167700_DEVELOP_124_2_327C34","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1242\/dev.100.2.279","article-title":"Regional specification within the mesoderm of early embryos of Xenopus laevis","volume":"100","author":"Dale","year":"1987","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C35","first-page":"167","article-title":"Goosecoid and the organizer","volume-title":"Development","author":"DeRobertis","year":"1992"},{"key":"2025021400183167700_DEVELOP_124_2_327C36","doi-asserted-by":"publisher","first-page":"10713","DOI":"10.1073\/pnas.92.23.10713","article-title":"Intraembryonic hematopoietic cell migration during vertebrate development","volume":"92","author":"Detrich","year":"1995","journal-title":"Proc. Nat. Acad. Sci.USA"},{"key":"2025021400183167700_DEVELOP_124_2_327C37","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/0925-4773(93)90067-8","article-title":"Altered Pax gene expression in murine notochord mutants: the notochord is required to initiate and maintain ventral identity in the somite","volume":"44","author":"Dietrich","year":"1993","journal-title":"Mech.Dev"},{"key":"2025021400183167700_DEVELOP_124_2_327C38","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1101\/gad.6.4.599","article-title":"A novel, activin-inducible, blastopore lip-specific gene of Xenopus laevis contains a fork head DNA-binding domain","volume":"6","author":"Dirksen","year":"1992","journal-title":"Genes Dev"},{"key":"2025021400183167700_DEVELOP_124_2_327C39","doi-asserted-by":"publisher","first-page":"749","DOI":"10.1242\/dev.106.4.749","article-title":"Cellular contacts required for neural induction in Xenopus embryos: evidence for two signals","volume":"106","author":"Dixon","year":"1989","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C40","doi-asserted-by":"publisher","first-page":"542","DOI":"10.1126\/science.1636091","article-title":"Planar induction of anteroposterior pattern in the developing central nervous system of Xenopus laevis","volume":"257","author":"Doniach","year":"1992","journal-title":"Science"},{"key":"2025021400183167700_DEVELOP_124_2_327C41","doi-asserted-by":"publisher","first-page":"1107","DOI":"10.1242\/dev.119.4.1107","article-title":"The expression of a zebrafish gene homologous to Drosophila snail suggests a conserved function in invertebrate and vertebrate gastrulation","volume":"119","author":"Hammerschmidt","year":"1993","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C42","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1242\/dev.123.1.95","article-title":"Mutations affecting morphogenesis during gastrulation and tail formation in the zebrafish, Danio rerio","volume":"123","author":"Hammerschmidt","year":"1996","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C43","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1038\/350339a0","article-title":"The cyclops mutation blocks specification of the floor plate of the zebrafish central nervous system","volume":"350","author":"Hatta","year":"1991","journal-title":"Nature"},{"key":"2025021400183167700_DEVELOP_124_2_327C44","doi-asserted-by":"publisher","first-page":"2061","DOI":"10.1073\/pnas.91.6.2061","article-title":"Midline signaling in the primordium of the zebrafish anterior central nervous system","volume":"91","author":"Hatta","year":"1994","journal-title":"Proc. Nat. Acad. Sci. USA"},{"key":"2025021400183167700_DEVELOP_124_2_327C45","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1126\/science.8036493","article-title":"Contribution of early cells to the fate map of the zebrafish gastrula","volume":"265","author":"Helde","year":"1994","journal-title":"Science"},{"key":"2025021400183167700_DEVELOP_124_2_327C46","doi-asserted-by":"publisher","first-page":"1007","DOI":"10.1242\/dev.122.3.1007","article-title":"TGF-beta signals and a prepattern in Xenopus laevis endodermal development","volume":"122","author":"Henry","year":"1996","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C47","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1038\/343617a0","article-title":"Cloning of the T gene required in mesoderm formation in the mouse","volume":"343","author":"Herrman","year":"1990","journal-title":"Nature"},{"key":"2025021400183167700_DEVELOP_124_2_327C48","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1016\/0168-9525(90)90011-T","article-title":"The T genes in embryogenesis","volume":"10","author":"Herrmann","year":"1994","journal-title":"Trends in Genetics"},{"key":"2025021400183167700_DEVELOP_124_2_327C49","doi-asserted-by":"publisher","first-page":"728","DOI":"10.1038\/348728a0","article-title":"Cell-autonomous action of zebrafish spt-1 mutation in specific mesodermal precursors","volume":"348","author":"Ho","year":"1990","journal-title":"Nature"},{"key":"2025021400183167700_DEVELOP_124_2_327C50","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1038\/376249a0","article-title":"A conserved system for dorsal-ventral patterning in insects and vertebrates involving sog and chordin","volume":"376","author":"Holley","year":"1995","journal-title":"Nature"},{"key":"2025021400183167700_DEVELOP_124_2_327C51","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1016\/0959-437X(95)90054-K","article-title":"Signalling by hedgehog family proteins in Drosophila and vertebrate development","volume":"5","author":"Ingham","year":"1995","journal-title":"Curr. Opin. Genet. Dev"},{"key":"2025021400183167700_DEVELOP_124_2_327C52","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1006\/dbio.1995.1289","article-title":"Temporal and spatial patterns of gene expression for the hatching enzyme in the teleost embryo, Oryzias latipes","volume":"171","author":"Inohaya","year":"1995","journal-title":"Dev. Biol"},{"key":"2025021400183167700_DEVELOP_124_2_327C53","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1002\/aja.1001990102","article-title":"Developmental regulation of islet-1 mRNA expression during neuronal differentiation in embryonic zebrafish","volume":"199","author":"Inoue","year":"1994","journal-title":"Dev. Dyn"},{"key":"2025021400183167700_DEVELOP_124_2_327C54","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1007\/BF00228439","article-title":"Onotogeny of avian extrinsic ocular muscles. I. A light- and electron-microscopic study","volume":"237","author":"Jacob","year":"1984","journal-title":"Cell Tissue Res"},{"key":"2025021400183167700_DEVELOP_124_2_327C55","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1002\/jez.1401670106","article-title":"Heart induction in salamanders","volume":"167","author":"Jacobson","year":"1968","journal-title":"J. Exp. Zool"},{"key":"2025021400183167700_DEVELOP_124_2_327C56","doi-asserted-by":"publisher","first-page":"1277","DOI":"10.1093\/genetics\/142.4.1277","article-title":"Centromere-linkage analysis and consolidation of the zebrafish genetic map","volume":"142","author":"Johnson","year":"1996","journal-title":"Genetics"},{"key":"2025021400183167700_DEVELOP_124_2_327C57","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1007\/BF02427884","article-title":"The possible role of mesodermal growth factors in the formation of endoderm","volume":"202","author":"Jones","year":"1993","journal-title":"Roux\u2019s Arch. Dev. Biol"},{"key":"2025021400183167700_DEVELOP_124_2_327C58","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/0168-9525(94)90220-8","article-title":"Whole-mount in situ hybridizations on zebrafish embryos using a mixture of digoxigenin- and fluorescein-labelled probes","volume":"10","author":"Jowett","year":"1994","journal-title":"Trends Genetics"},{"key":"2025021400183167700_DEVELOP_124_2_327C59","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1016\/0012-1606(76)90127-5","article-title":"Vital dye mapping of the gastrula and neurula of Xenopus laevis. II. Prospective areas and morphogenetic movements of the deep layer","volume":"51","author":"Keller","year":"1976","journal-title":"Dev. Biol"},{"key":"2025021400183167700_DEVELOP_124_2_327C60","doi-asserted-by":"publisher","first-page":"596","DOI":"10.1126\/science.7939714","article-title":"Vertebrate embryonic induction: Mesodermal and neural patterning","volume":"266","author":"Kessler","year":"1994","journal-title":"Science"},{"key":"2025021400183167700_DEVELOP_124_2_327C61","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1242\/dev.116.1.1","article-title":"Synergistic principles of development: overlapping patterning systems in Xenopus mesoderm induction. [Review]","volume":"116","author":"Kimelman","year":"1992","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C62","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1002\/aja.1002030302","article-title":"Stages of embryonic development of the zebrafish","volume":"203","author":"Kimmel","year":"1995","journal-title":"Dev. Dynam"},{"key":"2025021400183167700_DEVELOP_124_2_327C63","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1242\/dev.108.4.581","article-title":"Origin and organization of the zebrafish fate map","volume":"108","author":"Kimmel","year":"1990","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C64","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/0092-8674(92)90121-R","article-title":"F-spondin: a gene expressed at high levels in the floor plate encodes a secreted protein that promotes neural cell adhesion and neurite extension","volume":"69","author":"Klar","year":"1992","journal-title":"Cell"},{"key":"2025021400183167700_DEVELOP_124_2_327C65","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1242\/dev.123.1.451","article-title":"A reference cross DNA panel for zebrafish (Danio rerio) anchored with simple sequence length polymorphisms","volume":"123","author":"Knapik","year":"1996","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C66","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1016\/0925-4773(92)90007-7","article-title":"Activin A induced expression of a fork head related gene in posterior chordamesoderm (notochord) of Xenopus laevis embryos","volume":"38","author":"Knoechel","year":"1992","journal-title":"Mech. Dev"},{"key":"2025021400183167700_DEVELOP_124_2_327C67","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1242\/dev.118.2.417","article-title":"Zebrafish primary neurons initiate expression of the LIM homeodomain protein Isl-1 at the end of gastrulation","volume":"118","author":"Korzh","year":"1993","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C68","doi-asserted-by":"publisher","first-page":"1431","DOI":"10.1016\/0092-8674(93)90628-4","article-title":"A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos","volume":"75","author":"Krauss","year":"1993","journal-title":"Cell"},{"key":"2025021400183167700_DEVELOP_124_2_327C69","doi-asserted-by":"publisher","first-page":"3609","DOI":"10.1002\/j.1460-2075.1991.tb04927.x","article-title":"Zebrafish pax[zf-a]: a paired box-containing gene expressed in the neural tube","volume":"10","author":"Krauss","year":"1991","journal-title":"EMBO Journal"},{"key":"2025021400183167700_DEVELOP_124_2_327C70","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1038\/360087a0","article-title":"Zebrafish pax[b] is involved in the formation of the midbrain-hindbrain boundary","volume":"360","author":"Krauss","year":"1992","journal-title":"Nature"},{"key":"2025021400183167700_DEVELOP_124_2_327C71","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1126\/science.8235591","article-title":"Neural induction by the secreted polypeptide noggin","volume":"262","author":"Lamb","year":"1993","journal-title":"Science"},{"key":"2025021400183167700_DEVELOP_124_2_327C72","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1007\/BF01503740","article-title":"Ueber die Induktionsfaehigkeit der verschiedenen Bezirke der Neurula von Urodelen","volume":"21","author":"Mangold","year":"1933","journal-title":"Naturwissenschaften"},{"key":"2025021400183167700_DEVELOP_124_2_327C73","doi-asserted-by":"publisher","first-page":"2646","DOI":"10.1101\/gad.9.21.2646","article-title":"Mouse Otx2 functions in the formation and patterning of rostral head","volume":"9","author":"Matsuo","year":"1995","journal-title":"Genes & Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C74","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1242\/dev.119.3.567","article-title":"Postimplantation expression patterns indicate a role for the mouse forkhead\/HNF-3alpha, beta and gamma genes in determination of the definitive endoderm, chordamesoderm and neuroectoderm","volume":"119","author":"Monaghan","year":"1993","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C75","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1002\/bies.950150204","article-title":"In pursuit of the functions of the Wnt family of Developmental Regulators-Insights from Xenopus laevis","volume":"15","author":"Moon","year":"1993","journal-title":"BioEssays"},{"key":"2025021400183167700_DEVELOP_124_2_327C76","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/S0960-9822(00)00048-8","article-title":"Large-scale mutagenesis in the zebrafish: in search of genes controlling development in a vertebrate","volume":"4","author":"Mullins","year":"1994","journal-title":"Curr. Biol"},{"key":"2025021400183167700_DEVELOP_124_2_327C77","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1242\/dev.121.2.515","article-title":"An inductive role for the endoderm in Xenopus cardiogenesis","volume":"121","author":"Nascone","year":"1995","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C78","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1007\/BF00578701","article-title":"The formation of the mesoderm in urodelean amphibians. I. The induction by the endoderm","volume":"162","author":"Nieuwkoop","year":"1969","journal-title":"Wilhelm Roux Arch. Dev. Biol"},{"key":"2025021400183167700_DEVELOP_124_2_327C79","doi-asserted-by":"publisher","first-page":"1351","DOI":"10.1242\/dev.121.5.1351","article-title":"Patterning of the mesoderm in Xenopus: dose-dependent and synergistic effects of Brachyury and Pintallavis","volume":"121","author":"O\u2019Reilly","year":"1995","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C80","doi-asserted-by":"publisher","first-page":"1087","DOI":"10.1093\/nar\/21.5.1087","article-title":"Cloning of the zebrafish krox-20 gene (krx-20) and its expression during hindbrain development","volume":"21","author":"Oxtoby","year":"1993","journal-title":"Nucl. Acids Res"},{"key":"2025021400183167700_DEVELOP_124_2_327C81","doi-asserted-by":"publisher","first-page":"961","DOI":"10.1242\/dev.117.3.961","article-title":"Xenopus distal-less related homeobox genes are expressed in the developing forebrain and are induced by planar signals","volume":"117","author":"Papalopulu","year":"1993","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C82","doi-asserted-by":"publisher","first-page":"985","DOI":"10.1126\/science.2237443","article-title":"Mesodermal control of neural cell identity: floor plate induction by the notochord","volume":"250","author":"Placzek","year":"1990","journal-title":"Science"},{"key":"2025021400183167700_DEVELOP_124_2_327C83","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1126\/science.8171321","article-title":"A genetic linkage map for the zebrafish","volume":"264","author":"Postlethwait","year":"1994","journal-title":"Science"},{"key":"2025021400183167700_DEVELOP_124_2_327C84","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1242\/dev.114.3.643","article-title":"Sequence and expression pattern of pax-6 are highly conserved between zebrafish and mice","volume":"114","author":"P\u00fcschel","year":"1992","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C85","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1016\/0925-4773(92)90053-M","article-title":"Comparative analysis of Pax-2 protein distributions during neurulation in mice and zebrafish","volume":"38","author":"P\u00fcschel","year":"1992","journal-title":"Mech. Dev"},{"key":"2025021400183167700_DEVELOP_124_2_327C86","doi-asserted-by":"publisher","first-page":"769","DOI":"10.1016\/0092-8674(85)90273-9","article-title":"Identification and cloning of localized maternal RNAs from Xenopus eggs","volume":"42","author":"Rebagliati","year":"1985","journal-title":"Cell"},{"key":"2025021400183167700_DEVELOP_124_2_327C87","doi-asserted-by":"publisher","first-page":"3005","DOI":"10.1242\/dev.121.9.3005","article-title":"Goosecoid is not an essential component of the mouse gastrula organizer but is required for craniofacial and rib development","volume":"121","author":"Rivera-Perez","year":"1995","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C88","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1016\/0092-8674(94)90514-2","article-title":"Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord","volume":"76","author":"Roelink","year":"1994","journal-title":"Cell"},{"key":"2025021400183167700_DEVELOP_124_2_327C89","doi-asserted-by":"publisher","first-page":"965","DOI":"10.1016\/0092-8674(89)90335-8","article-title":"Mix.1, a homeobox mRNA inducible by mesoderm inducers, is expressed mostly in the presumptive endodermal cells of Xenopus embryos","volume":"57","author":"Rosa","year":"1989","journal-title":"Cell"},{"key":"2025021400183167700_DEVELOP_124_2_327C90","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1242\/dev.116.1.67","article-title":"Planar and vertical signals in the induction and patterning of the Xenopus nervous system","volume":"115","author":"Ruiz i Altaba","year":"1992","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C91","doi-asserted-by":"publisher","first-page":"1276","DOI":"10.1002\/neu.480241004","article-title":"Induction and axial patterning of the neural plate: planar and vertical signals","volume":"24","author":"Ruiz i Altaba","year":"1993","journal-title":"J. Neurobiol"},{"key":"2025021400183167700_DEVELOP_124_2_327C92","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1242\/dev.116.1.81","article-title":"Pintallavis, a gene expressed in the organizer and midline cells of frog embryos: involvement in the development of the neural axis","volume":"116","author":"Ruiz i Altaba","year":"1992","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C93","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/0925-4773(93)90060-B","article-title":"Sequential expression of HNF-3a and HNF-3? by embryonic organizing centers: the dorsal lip\/node, notochord, and floor plate","volume":"44","author":"Ruiz i Altaba","year":"1993","journal-title":"Mech. Dev"},{"key":"2025021400183167700_DEVELOP_124_2_327C94","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1016\/0959-437X(93)90100-4","article-title":"Midline cells and the organization of the vertebrate neuraxis","volume":"3","author":"Ruiz i Altaba","year":"1993","journal-title":"Current Opinion in Genetics & Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C95","doi-asserted-by":"publisher","first-page":"779","DOI":"10.1016\/0092-8674(94)90068-X","article-title":"Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes","volume":"79","author":"Sasai","year":"1994","journal-title":"Cell"},{"key":"2025021400183167700_DEVELOP_124_2_327C96","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1242\/dev.118.1.47","article-title":"Differential expression of multiple forkhead related genes during gastrulation and axial pattern formation in the mouse embryo","volume":"118","author":"Sasaki","year":"1993","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C97","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1242\/dev.108.3.461","article-title":"The role of the dorsal lip in the induction of heart mesoderm in Xenopus laevis","volume":"108","author":"Sater","year":"1990","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C98","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1242\/dev.123.1.165","article-title":"Mutations affecting the development of the embryonic zebrafish brain","volume":"123","author":"Schier","year":"1996","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C99","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1242\/dev.120.4.843","article-title":"Expression of zebrafish goosecoid and no tail gene products in wild-type and mutant no tail embryos","volume":"120","author":"Schulte-Merker","year":"1994","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C100","doi-asserted-by":"publisher","first-page":"1021","DOI":"10.1242\/dev.116.4.1021","article-title":"The protein product of the zebrafish homologue of the mouse T gene is expressed in nuclei of the germ ring and the notochord of the early embryo","volume":"116","author":"Schulte-Merker","year":"1992","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C101","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.1242\/dev.120.4.1009","article-title":"No tail (Ntl) is the zebrafish homologue of the mouse T (Brachyury) gene","volume":"120","author":"Schulte-Merker","year":"1994","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C102","doi-asserted-by":"publisher","first-page":"4203","DOI":"10.1242\/dev.121.12.4203","article-title":"Induction of avian cardiac myogenesis by anterior endoderm","volume":"121","author":"Schultheiss","year":"1995","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C103","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/0922-3371(90)90109-A","article-title":"Tissue interactions involving cranial neural crest in cartilage formation in Xenopus laevis (Daudin)","volume":"32","author":"Seufert","year":"1990","journal-title":"Cell Diff. Dev"},{"key":"2025021400183167700_DEVELOP_124_2_327C104","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1038\/374425a0","article-title":"Requirement for Lim1 in head-organizer function","volume":"374","author":"Shawlot","year":"1995","journal-title":"Nature"},{"key":"2025021400183167700_DEVELOP_124_2_327C105","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1242\/dev.116.4.887","article-title":"The epithelium of the dorsal marginal zone of Xenopus has organizer properties","volume":"116","author":"Shih","year":"1992","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C106","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1038\/326197a0","article-title":"Mesoderm induction in early Xenopus embryos by heparin binding growth factors","volume":"326","author":"Slack","year":"1988","journal-title":"Nature"},{"key":"2025021400183167700_DEVELOP_124_2_327C107","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1016\/S0960-9822(94)00027-8","article-title":"Inducing factors in Xenopus early embryos","volume":"4","author":"Slack","year":"1994","journal-title":"Curr. Biol"},{"key":"2025021400183167700_DEVELOP_124_2_327C108","doi-asserted-by":"publisher","first-page":"856","DOI":"10.1016\/0955-0674(95)80070-0","article-title":"Mesoderm-inducing factors and mesodermal patterning","volume":"7","author":"Smith","year":"1995","journal-title":"Curr. Opin. Cell. Biol"},{"key":"2025021400183167700_DEVELOP_124_2_327C109","first-page":"299","article-title":"Dorsalization and neural induction: properties of the organizer in Xenopus laevis","volume":"78","author":"Smith","year":"1983","journal-title":"J. Embryol. Exp. Morphol"},{"key":"2025021400183167700_DEVELOP_124_2_327C110","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/0092-8674(91)90573-H","article-title":"Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction","volume":"67","author":"Smith","year":"1991","journal-title":"Cell"},{"key":"2025021400183167700_DEVELOP_124_2_327C111","doi-asserted-by":"publisher","first-page":"1401","DOI":"10.1093\/genetics\/136.4.1401","article-title":"Efficient recovery of ENU-induced mutations from the zebrafish germline","volume":"136","author":"Solnica-Krezel","year":"1994","journal-title":"Genetics"},{"key":"2025021400183167700_DEVELOP_124_2_327C112","first-page":"67","article-title":"Mutations affecting cell fates and cellular rearrangements during gastrulation in zebrafish","volume-title":"Development","author":"Solnica-Krezel","year":"1996"},{"key":"2025021400183167700_DEVELOP_124_2_327C113","first-page":"599","article-title":"Ueber die Induktion von Embryonalanlagen durch Implantation artfremder Organisatoren","volume":"100","author":"Spemann","year":"1924","journal-title":"Wilhelm Roux Arch. Entw. Mech. Org"},{"key":"2025021400183167700_DEVELOP_124_2_327C114","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1007\/BF01380646","article-title":"Ueber den Anteil von Implantat und Wirtskeim an der Orientierung und Beschaffenheit der induzierten Embryonalanlage","volume":"123","author":"Spemann","year":"1931","journal-title":"Roux\u2019s Arch. Entw. Mech. Org"},{"key":"2025021400183167700_DEVELOP_124_2_327C115","doi-asserted-by":"crossref","DOI":"10.1097\/00000441-193811000-00047","volume-title":"Embryonic Development and Induction","author":"Spemann","year":"1938"},{"key":"2025021400183167700_DEVELOP_124_2_327C116","doi-asserted-by":"publisher","first-page":"1261","DOI":"10.1242\/dev.117.4.1261","article-title":"Lithium perturbation and goosecoid expression identify a dorsal specification pathway in the pregastrula zebrafish","volume":"117","author":"Stachel","year":"1993","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C117","doi-asserted-by":"publisher","first-page":"3141","DOI":"10.1242\/dev.121.10.3141","article-title":"Cloche, an early acting zebrafish gene, is required by both the endothelial and hematopoietic lineages","volume":"121","author":"Stainier","year":"1995","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C118","doi-asserted-by":"publisher","first-page":"1436","DOI":"10.1101\/gad.7.7b.1436","article-title":"Axial, a zebrafish gene expressed along the developing body axis, shows altered expression in cyclops mutant embryos","volume":"7","author":"Str\u00e4hle","year":"1993","journal-title":"Genes Dev"},{"key":"2025021400183167700_DEVELOP_124_2_327C119","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1101\/gad.6.3.356","article-title":"The LIM domain-containing homeo box gene Xlim-1 is expressed specifically in the organizer region of Xenopus gastrula embryos","volume":"6","author":"Taira","year":"1992","journal-title":"Genes & Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C120","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1038\/378150a0","article-title":"A homeobox gene essential for zebrafish notochord development","volume":"378","author":"Talbot","year":"1995","journal-title":"Nature"},{"key":"2025021400183167700_DEVELOP_124_2_327C121","doi-asserted-by":"publisher","first-page":"420","DOI":"10.1006\/dbio.1994.1212","article-title":"Goosecoid expression in neurectoderm and mesendoderm is disrupted in zebrafish cyclops gastrulas","volume":"164","author":"Thisse","year":"1994","journal-title":"Dev. Biol"},{"key":"2025021400183167700_DEVELOP_124_2_327C122","doi-asserted-by":"publisher","first-page":"1203","DOI":"10.1242\/dev.119.4.1203","article-title":"Structure of the zebrafish snail1 gene and its expression in wild-type, spadetail and no tail mutant embryos","volume":"119","author":"Thisse","year":"1993","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C123","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1242\/dev.121.2.383","article-title":"Nodal induces ectopic goosecoid and lim1 expression and axis duplication in zebrafish","volume":"121","author":"Toyama","year":"1995","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C124","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1007\/BF00315839","article-title":"Effects of the notochord on the differentiation of a floor plate area in the neural tube of the chick embryo","volume":"177","author":"van Straaten","year":"1988","journal-title":"Anat. Embryol"},{"key":"2025021400183167700_DEVELOP_124_2_327C125","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1007\/BF01744261","article-title":"Development of floor plate, neurons and axonal outgrowth pattern in the early spinal cord of the notochord-deficient chick embryo","volume":"184","author":"van Straaten","year":"1991","journal-title":"Anat. Embryol"},{"key":"2025021400183167700_DEVELOP_124_2_327C126","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1101\/gad.7.3.355","article-title":"Induction of the Xenopus organizer: expression and regulation of Xnot, a novel FGF and activin-regulated homeo box gene","volume":"7","author":"von Dassow","year":"1993","journal-title":"Genes Dev"},{"key":"2025021400183167700_DEVELOP_124_2_327C127","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1007\/BF00410750","article-title":"The extrinsic ocular muscles in birds are derived from the prechordal plate","volume":"71","author":"Wachtler","year":"1984","journal-title":"Naturwissenschaften"},{"key":"2025021400183167700_DEVELOP_124_2_327C128","article-title":"Origin and specification of the endoderm in the zebrafish","volume-title":"Danio rerio","author":"Warga","year":"1996"},{"key":"2025021400183167700_DEVELOP_124_2_327C129","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1242\/dev.122.1.271","article-title":"Developmental regulation of zebrafish myoD in wild-type, no tail and spadetail embryos","volume":"122","author":"Weinberg","year":"1996","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C130","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1016\/0092-8674(94)90523-1","article-title":"The winged-helix transcription factor HNF-3 beta is required for notochord development in the mouse embryo","volume":"78","author":"Weinstein","year":"1994","journal-title":"Cell"},{"key":"2025021400183167700_DEVELOP_124_2_327C131","volume-title":"The Zebrafish Book","author":"Westerfield","year":"1994"},{"key":"2025021400183167700_DEVELOP_124_2_327C132","doi-asserted-by":"publisher","first-page":"877","DOI":"10.1242\/dev.121.3.877","article-title":"The T gene is necessary for normal mesodermal morphogenetic cell movements during gastrulation","volume":"121","author":"Wilson","year":"1995","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C133","doi-asserted-by":"publisher","first-page":"1321","DOI":"10.1242\/dev.117.4.1321","article-title":"Chimeric analysis of T (Brachyury) gene function","volume":"117","author":"Wilson","year":"1993","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C134","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1242\/dev.105.4.787","article-title":"Xlhbox8: a novel Xenopus homeoprotein restricted to a narrow band of endoderm","volume":"105","author":"Wright","year":"1988","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C135","doi-asserted-by":"publisher","first-page":"2917","DOI":"10.1242\/dev.121.9.2917","article-title":"Targeted mutation of the murine goosecoid gene results in craniofacial defects and neonatal death","volume":"121","author":"Yamada","year":"1995","journal-title":"Development"},{"key":"2025021400183167700_DEVELOP_124_2_327C136","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1002\/aja.1002030308","article-title":"Expression of a type II collagen gene in the zebrafish embryonic axis","volume":"203","author":"Yan","year":"1995","journal-title":"Dev. Dynam"}],"container-title":["Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.biologists.com\/dev\/article-pdf\/124\/2\/327\/3123760\/develop_124_2_327.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/journals.biologists.com\/dev\/article-pdf\/124\/2\/327\/3123760\/develop_124_2_327.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,14]],"date-time":"2025-02-14T00:19:11Z","timestamp":1739492351000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.biologists.com\/dev\/article\/124\/2\/327\/39533\/The-one-eyed-pinhead-gene-functions-in-mesoderm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,1,15]]},"references-count":136,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1997,1,15]]}},"URL":"https:\/\/doi.org\/10.1242\/dev.124.2.327","relation":{},"ISSN":["0950-1991","1477-9129"],"issn-type":[{"value":"0950-1991","type":"print"},{"value":"1477-9129","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,1,15]]}}}