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Here we show that in the absence of the transcription factor neurogenin 2, cells from the cortex migrate into the GE in vitro and in vivo as detected in transgenic mice containing a lacZ gene in the neurogenin 2 locus. In contrast, the migration of cells from the GE is not affected. Molecular and cellular analysis of the cortico-striatal boundary revealed that neurogenin 2 regulates the fasciculation of the cortico-striatal boundary which may explain the non cell-autonomous nature of the migration defect as detected by in vitro transplantation. Taken together, these results show that distinct cues located in the cortico-striatal boundary restrict cells in the dorsal and ventral telencephalon.<\/jats:p>","DOI":"10.1242\/dev.128.24.5149","type":"journal-article","created":{"date-parts":[[2021,4,26]],"date-time":"2021-04-26T04:44:15Z","timestamp":1619412255000},"page":"5149-5159","source":"Crossref","is-referenced-by-count":29,"title":["The transcription factor neurogenin 2 restricts cell migration from the cortex to the striatum"],"prefix":"10.1242","volume":"128","author":[{"given":"Prisca","family":"Chapouton","sequence":"first","affiliation":[{"name":"Max-Planck Institute for Neurobiology, Am Klopferspitz 18A, D-82152 Planegg-Martinsried, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carol","family":"Schuurmans","sequence":"additional","affiliation":[{"name":"IGBMC, Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franc\u0327ois","family":"Guillemot","sequence":"additional","affiliation":[{"name":"IGBMC, Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magdalena","family":"Go\u0308tz","sequence":"additional","affiliation":[{"name":"Max-Planck Institute for Neurobiology, Am Klopferspitz 18A, D-82152 Planegg-Martinsried, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"237","reference":[{"key":"2021042604122690400_ANDERSON-ETAL-1997","doi-asserted-by":"crossref","unstructured":"Anderson, S. 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