{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T21:08:10Z","timestamp":1790802490080,"version":"4.1.0"},"reference-count":52,"publisher":"The Company of Biologists","issue":"4","license":[{"start":{"date-parts":[[2021,2,15]],"date-time":"2021-02-15T00:00:00Z","timestamp":1613347200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.biologists.com\/user-licence-1-1\/"}],"funder":[{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"crossref","award":["ANR-13-BSV2-0006"],"award-info":[{"award-number":["ANR-13-BSV2-0006"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"crossref","award":["ANR-17-CE13-0024"],"award-info":[{"award-number":["ANR-17-CE13-0024"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"crossref"}]},{"name":"LABEX SIGNALIFE","award":["ANR-11-LABX-0028-01"],"award-info":[{"award-number":["ANR-11-LABX-0028-01"]}]},{"name":"Universit\u00e9 C\u00f4te d'Azur Centre National pour la Recherche Scientifique"},{"DOI":"10.13039\/501100001677","name":"Institut national de la sant\u00e9 et de la recherche m\u00e9dicale","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001677","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,2,15]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>Basement membranes (BM) are extracellular matrices assembled into complex and highly organized networks essential for organ morphogenesis and function. However, little is known about the tissue origin of BM components and their dynamics in vivo. Here, we unravel the assembly and role of the BM main component, Collagen type IV (ColIV), in Drosophila ovarian stalk morphogenesis. Stalks are short strings of cells assembled through cell intercalation that link adjacent follicles and maintain ovarian integrity. We show that stalk ColIV has multiple origins and is assembled following a regulated pattern leading to a unique BM organisation. Absence of ColIV leads to follicle fusion, as observed upon ablation of stalk cells. ColIV and integrins are both required to trigger cell intercalation and maintain mechanically strong cell-cell attachment within the stalk. These results show how the dynamic assembly of a mosaic BM controls complex tissue morphogenesis and integrity.<\/jats:p>","DOI":"10.1242\/dev.195511","type":"journal-article","created":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T18:16:03Z","timestamp":1612203363000},"source":"Crossref","is-referenced-by-count":35,"title":["A dynamic and mosaic basement membrane controls cell intercalation in <i>Drosophila<\/i> ovaries"],"prefix":"10.1242","volume":"148","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7157-4456","authenticated-orcid":false,"given":"V\u00e9ronique","family":"Van De Bor","sequence":"first","affiliation":[{"name":"Universit\u00e9 C\u00f4te d'Azur, CNRS, Inserm, iBV, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Loreau","sequence":"additional","affiliation":[{"name":"Universit\u00e9 C\u00f4te d'Azur, CNRS, Inserm, iBV, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0884-1387","authenticated-orcid":false,"given":"Marilyne","family":"Malbouyres","sequence":"additional","affiliation":[{"name":"Institut de G\u00e9nomique Fonctionnelle de Lyon, ENS de Lyon - CNRS UMR 5242 - INRA USC 1370, 46, all\u00e9e d'Italie, 69364 Lyon cedex 07, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delphine","family":"Cerezo","sequence":"additional","affiliation":[{"name":"Universit\u00e9 C\u00f4te d'Azur, CNRS, Inserm, iBV, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Audrey","family":"Placenti","sequence":"additional","affiliation":[{"name":"Universit\u00e9 C\u00f4te d'Azur, CNRS, Inserm, iBV, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2915-5359","authenticated-orcid":false,"given":"Florence","family":"Ruggiero","sequence":"additional","affiliation":[{"name":"Institut de G\u00e9nomique Fonctionnelle de Lyon, ENS de Lyon - CNRS UMR 5242 - INRA USC 1370, 46, all\u00e9e d'Italie, 69364 Lyon cedex 07, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7296-324X","authenticated-orcid":false,"given":"St\u00e9phane","family":"Noselli","sequence":"additional","affiliation":[{"name":"Universit\u00e9 C\u00f4te d'Azur, CNRS, Inserm, iBV, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"237","published-online":{"date-parts":[[2021,2,26]]},"reference":[{"key":"2021042701114411400_DEV195511C1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41598-016-0001-8","article-title":"The mammalian LINC complex regulates genome transcriptional responses to substrate rigidity","volume":"6","author":"Alam","year":"2016","journal-title":"Sci. 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