{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T01:03:59Z","timestamp":1755219839457,"version":"3.43.0"},"reference-count":3,"publisher":"The Company of Biologists","issue":"15","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,8,1]]},"abstract":"<jats:p>Pyruvate dehydrogenase E1 subunit alpha 2 (PDHA2) is a testis-specific mitochondrial protein involved in energy metabolism and spermatogenesis. In their study, Keisuke Shimada and colleagues show that PDHA2 is crucial for normal spermatogenesis and it likely compensates for Pdha1, which is normally silenced during meiosis, in male germ cells. To find out more about their work, we spoke to the first author, Chen Pan, and the corresponding author, Keisuke Shimada, Associate Professor at the Laboratory of Disease Models, School of Veterinary Medicine, Rakuno Gakuen University, Japan.<\/jats:p>","DOI":"10.1242\/dev.205120","type":"journal-article","created":{"date-parts":[[2025,8,7]],"date-time":"2025-08-07T10:56:34Z","timestamp":1754564194000},"source":"Crossref","is-referenced-by-count":0,"title":["The people behind the papers \u2013 Chen Pan and Keisuke Shimada"],"prefix":"10.1242","volume":"152","member":"237","published-online":{"date-parts":[[2025,8,7]]},"reference":[{"key":"2025080706562554700_DEV205120C1","doi-asserted-by":"publisher","first-page":"dev204683","DOI":"10.1242\/dev.204683","article-title":"Compensation for X-linked Pdha1 silencing by Pdha2 is essential for meiotic double-strand break repair in spermatogenesis","volume":"152","author":"Pan","year":"2025","journal-title":"Development"},{"key":"2025080706562554700_DEV205120C2","doi-asserted-by":"publisher","first-page":"e2018355118","DOI":"10.1073\/pnas.2018355118","article-title":"ARMC12 regulates spatiotemporal mitochondrial dynamics during spermiogenesis and is required for male fertility","volume":"118","author":"Shimada","year":"2021","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2025080706562554700_DEV205120C3","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/j.tem.2004.01.007","article-title":"X chromosomes, retrogenes and their role in male reproduction","volume":"15","author":"Wang","year":"2004","journal-title":"Trends Endocrinol. Metab."}],"container-title":["Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.biologists.com\/dev\/article-pdf\/doi\/10.1242\/dev.205120\/3660565\/dev205120.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/journals.biologists.com\/dev\/article-pdf\/doi\/10.1242\/dev.205120\/3660565\/dev205120.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,7]],"date-time":"2025-08-07T10:56:34Z","timestamp":1754564194000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.biologists.com\/dev\/article\/152\/15\/dev205120\/368832\/The-people-behind-the-papers-Chen-Pan-and-Keisuke"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,1]]},"references-count":3,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2025,8,1]]}},"URL":"https:\/\/doi.org\/10.1242\/dev.205120","relation":{},"ISSN":["0950-1991","1477-9129"],"issn-type":[{"value":"0950-1991","type":"print"},{"value":"1477-9129","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,1]]},"article-number":"dev205120"}}