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Specific zinc-finger proteins recruited to PCs link chromosomes to nuclear envelope proteins \u2013 and through them to the microtubule cytoskeleton \u2013 thereby stimulating chromosome movements in early prophase, which are thought to be important for homolog sorting. This mechanism appears to be a variant of the \u2018telomere bouquet\u2019 process, in which telomeres cluster on the nuclear envelope, connect chromosomes through nuclear envelope proteins to the cytoskeleton and lead chromosome movements that promote homologous synapsis. In Drosophila males, which undergo meiosis without recombination, pairing of the largely non-homologous X and Y chromosomes occurs at specific repetitive sequences in the ribosomal DNA. Although no other clear examples of PC-based pairing mechanisms have been described, there is evidence for special roles of telomeres and centromeres in aspects of chromosome pairing, synapsis and segregation; these roles are in some cases similar to those of PCs.<\/jats:p>","DOI":"10.1242\/jcs.006387","type":"journal-article","created":{"date-parts":[[2011,5,30]],"date-time":"2011-05-30T20:33:38Z","timestamp":1306787618000},"page":"1955-1963","source":"Crossref","is-referenced-by-count":81,"title":["Homologous pairing and the role of pairing centers in meiosis"],"prefix":"10.1242","volume":"124","author":[{"given":"Jui-He","family":"Tsai","sequence":"first","affiliation":[{"name":"Department of Biochemistry, Cellular, and Molecular Biology, University of Tennessee, Knoxville, TN 37996, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce D.","family":"McKee","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Cellular, and Molecular Biology, University of Tennessee, Knoxville, TN 37996, USA"},{"name":"Genome Science and Technology Program, University of Tennessee, Knoxville, TN 37996, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"237","reference":[{"key":"2021042521282906800_R1","doi-asserted-by":"crossref","first-page":"e1001219","DOI":"10.1371\/journal.pgen.1001219","article-title":"Leptotene\/zygotene chromosome movement via the SUN\/KASH protein bridge in Caenorhabditis elegans","volume":"6","author":"Baudrimont","year":"2010","journal-title":"PLoS Genet."},{"key":"2021042521282906800_R2","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0092-8674(04)00292-2","article-title":"Crossover\/noncrossover differentiation, synaptonemal complex formation, and regulatory surveillance at the leptotene\/zygotene transition of meiosis","volume":"117","author":"Borner","year":"2004","journal-title":"Cell"},{"key":"2021042521282906800_R3","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1159\/000121080","article-title":"The cytogenetics of homologous chromosome pairing in meiosis in plants","volume":"120","author":"Bozza","year":"2008","journal-title":"Cytogenet. 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