{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T18:51:31Z","timestamp":1791053491174,"version":"4.1.0"},"reference-count":64,"publisher":"The Company of Biologists","issue":"7","license":[{"start":{"date-parts":[[1998,4,1]],"date-time":"1998-04-01T00:00:00Z","timestamp":891388800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.biologists.com\/user-licence-1-1\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1998,4,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>SCC9 cells, derived from a squamous carcinoma of the tongue, were shown to lack E-cadherin but express \u03b1- and \u03b2-catenins and N-cadherin. These cells also lack plakoglobin expression, do not assemble desmosomes and exhibit the typical morphology and growth properties of transformed cells. The N-cadherin expressed in SCC9 cells has properties similar to other classical cadherins, including interactions with the catenins. We transfected SCC9 cells with a full-length c DNA for L-CAM (liver cell adhesion molecule), the functional chicken homologue of E-cadherin. The exogenously expressed L-CAM formed complexes with catenins and the cytoskeleton and induced a morphological transition from fibroblastoid to epithelioid, conferred density-dependent growth inhibition, increased aggregation ability, and increased synthesis and stability of \u03b1- and \u03b2-catenins. Coincident with these phenotypic changes, we detected a significant reduction in the level of endogenous N-cadherin, primarily as a result of rapid degradation of this protein in L-CAM-expressing cells. These results show the abnormal expression of N-cadherin in these transformed epidermoid cells, demonstrate the dynamics of the relationship between two cadherins, and provide a model system for the functional analysis of the tumor suppressor activity of E-cadherin in carcinomas.<\/jats:p>","DOI":"10.1242\/jcs.111.7.1005","type":"journal-article","created":{"date-parts":[[2021,4,25]],"date-time":"2021-04-25T17:11:37Z","timestamp":1619370697000},"page":"1005-1019","source":"Crossref","is-referenced-by-count":26,"title":["L-CAM expression induces fibroblast-epidermoid transition in squamous carcinoma cells and down-regulates the endogenous N-cadherin"],"prefix":"10.1242","volume":"111","author":[{"given":"Zhi","family":"Li","sequence":"first","affiliation":[{"name":"1 Departments of Cell Biology and Anatomy, Edmonton, Alberta, Canada, T6G 2H7"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Warren J.","family":"Gallin","sequence":"additional","affiliation":[{"name":"1 Departments of Cell Biology and Anatomy, Edmonton, Alberta, Canada, T6G 2H7"},{"name":"2 Biological Sciences and, Edmonton, Alberta, Canada, T6G 2H7"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gille","family":"Lauzon","sequence":"additional","affiliation":[{"name":"University of Alberta 3 Dermatology , , Edmonton, Alberta, Canada, T6G 2H7"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manijeh","family":"Pasdar","sequence":"additional","affiliation":[{"name":"1 Departments of Cell Biology and Anatomy, Edmonton, Alberta, Canada, T6G 2H7"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"237","published-online":{"date-parts":[[1998,4,1]]},"reference":[{"key":"2024010622541640000_JOCES_111_7_1005C1","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1002\/(SICI)1097-4644(19960616)61:4&lt;514::AID-JCB4&gt;3.0.CO;2-R","article-title":"Cadherin-catenin complex: protein interactions and their implications for cadherin function","volume":"61","author":"Aberle","year":"1996","journal-title":"J. Cell. Biochem"},{"key":"2024010622541640000_JOCES_111_7_1005C2","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/978-3-0348-7494-6_8","article-title":"The role of E-cadherin and scatter factor in tumor invasion and cell motility","volume-title":"Cell Motility Factors","author":"Behrens","year":"1991"},{"key":"2024010622541640000_JOCES_111_7_1005C3","first-page":"97","volume":"17","author":"Birchmeier","year":"1995","journal-title":"E-cadherin as a tumor (invasion) suppressor gene BioEssays"},{"key":"2024010622541640000_JOCES_111_7_1005C4","first-page":"11","article-title":"Cadherin expression in carcinomas: role in the formation of cell junctions and the prevention of invasiveness","volume":"198","author":"Birchmeier","year":"1994","journal-title":"Biochem. Biophys. Acta"},{"key":"2024010622541640000_JOCES_111_7_1005C5","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1002\/mc.2940030603","article-title":"Tumor suppressor genes: possible functions in negative regulation of cell proliferation","volume":"3","author":"Boyd","year":"1990","journal-title":"Molec. Carcinogen"},{"key":"2024010622541640000_JOCES_111_7_1005C6","doi-asserted-by":"publisher","first-page":"6835","DOI":"10.1016\/S0021-9258(17)39925-8","article-title":"Adhesion among neural cells of the chick embryo. II. Purification and characterization of a cell adhesion molecule from neural retina","volume":"252","author":"Brackenbury","year":"1977","journal-title":"J. Biol. Chem"},{"key":"2024010622541640000_JOCES_111_7_1005C7","doi-asserted-by":"publisher","first-page":"1991","DOI":"10.1073\/pnas.81.7.1991","article-title":"Genomic sequencing","volume":"81","author":"Church","year":"1984","journal-title":"Proc. Nat. Acad Sci USA"},{"key":"2024010622541640000_JOCES_111_7_1005C8","doi-asserted-by":"publisher","first-page":"1063","DOI":"10.1016\/0092-8674(86)90706-3","article-title":"Plakoglobin: A protein common to different kinds of intercellular adhering junctions","volume":"46","author":"Cowin","year":"1986","journal-title":"Cell"},{"key":"2024010622541640000_JOCES_111_7_1005C9","doi-asserted-by":"publisher","first-page":"1105","DOI":"10.1083\/jcb.132.6.1105","article-title":"Binding to cadherins antagonizes the signaling activity of \u03b2-catenin during axis formation in Xenopus","volume":"132","author":"Fagotto","year":"1996","journal-title":"J. Cell Biol"},{"key":"2024010622541640000_JOCES_111_7_1005C10","doi-asserted-by":"publisher","first-page":"1038","DOI":"10.1073\/pnas.80.4.1038","article-title":"Characterization of L-CAM, a major cell adhesion molecule from embryonic liver cells","volume":"80","author":"Gallin","year":"1983","journal-title":"Proc. Nat. Acad Sci USA"},{"key":"2024010622541640000_JOCES_111_7_1005C11","doi-asserted-by":"publisher","first-page":"2808","DOI":"10.1073\/pnas.84.9.2808","article-title":"Sequence analysis of a cDNA clone encoding the liver cell adhesion molecule, L-CAM","volume":"84","author":"Gallin","year":"1987","journal-title":"Proc. Nat. Acad Sci USA"},{"key":"2024010622541640000_JOCES_111_7_1005C12","doi-asserted-by":"publisher","first-page":"797805","DOI":"10.1016\/0955-0674(93)90028-O","article-title":"The structural and functional analysis of cadherin calcium-dependent cell adhesion molecules","volume":"5","author":"Grunwald","year":"1993","journal-title":"Curr. Opin. Cell Biol"},{"key":"2024010622541640000_JOCES_111_7_1005C13","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1016\/0955-0674(95)80104-9","article-title":"Signal transduction by \u03b2-catenin","volume":"7","author":"Gumbiner","year":"1995","journal-title":"Curr. Opin. Cell Biol"},{"key":"2024010622541640000_JOCES_111_7_1005C14","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1016\/S0092-8674(00)81279-9","article-title":"Cell adhesion: the molecular basis of tissue architecture and morphogenesis","volume":"84","author":"Gumbiner","year":"1996","journal-title":"Cell"},{"key":"2024010622541640000_JOCES_111_7_1005C15","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1073\/pnas.94.1.242","article-title":"A Drosophila homolog of the tumor suppressor gene adenomatous polyposis coli down-regulates \u03b2 -catenin but its zygotic expression is not essential for the regulation of Armadillo","volume":"94","author":"Hayashi","year":"1997","journal-title":"Proc. Nat. Acad Sci USA"},{"key":"2024010622541640000_JOCES_111_7_1005C16","doi-asserted-by":"publisher","first-page":"1327","DOI":"10.1083\/jcb.125.6.1327","article-title":"Dynamics of cadherin\/catenin complex formation: Novel protein interactions and pathways of complex assembly","volume":"125","author":"Hinck","year":"1994","journal-title":"J. Cell Biol"},{"key":"2024010622541640000_JOCES_111_7_1005C17","doi-asserted-by":"publisher","first-page":"2501","DOI":"10.1083\/jcb.105.6.2501","article-title":"Calcium-dependent cell-cell adhesion molecules (cadherins): subclass specificities and possible involvement of actin bundles","volume":"105","author":"Hirano","year":"1987","journal-title":"J. Cell Biol"},{"key":"2024010622541640000_JOCES_111_7_1005C18","doi-asserted-by":"publisher","first-page":"1643","DOI":"10.1083\/jcb.135.6.1643","article-title":"Expression of N-cadherin by human squamous carcinoma cells induces a scattered fibroblastic phenotype with disrupted cell-cell adhesion","volume":"135","author":"Islam","year":"1996","journal-title":"J. Cell Biol"},{"key":"2024010622541640000_JOCES_111_7_1005C19","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1006\/excr.1993.1191","article-title":"P- and E-cadherin are in separate complexes in cell expressing both cadherins","volume":"207","author":"Johnson","year":"1993","journal-title":"Exp. Cell Res"},{"key":"2024010622541640000_JOCES_111_7_1005C20","doi-asserted-by":"publisher","first-page":"1067","DOI":"10.1006\/bbrc.1995.1443","article-title":"c-erb B-2 gene product directly associates with \u03b2-catenin and plakoglobin","volume":"298","author":"Kanani","year":"1995","journal-title":"Biochem. Biophys. Res. Comm"},{"key":"2024010622541640000_JOCES_111_7_1005C21","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1016\/0092-8674(92)90404-Z","article-title":"Regulation of embryonic cell adhesion by the cadherin cytoplasmic domain","volume":"69","author":"Kintner","year":"1992","journal-title":"Cell"},{"key":"2024010622541640000_JOCES_111_7_1005C22","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1083\/jcb.118.3.671","article-title":"Plakoglobin, or an 83-kD homologue distinct from \u03b2-catenin, interacts with E-cadherin and N-cadherin","volume":"118","author":"Knudsen","year":"1992","journal-title":"J. Cell Biol"},{"key":"2024010622541640000_JOCES_111_7_1005C23","doi-asserted-by":"publisher","first-page":"1784","DOI":"10.1126\/science.275.5307.1784","article-title":"Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-\/- colon carcinoma","volume":"275","author":"Korinek","year":"1997","journal-title":"Science"},{"key":"2024010622541640000_JOCES_111_7_1005C24","doi-asserted-by":"publisher","first-page":"31214","DOI":"10.1016\/S0021-9258(18)47411-X","article-title":"Posttranslational regulation of plakoglobin expression","volume":"269","author":"Kowalczyk","year":"1994","journal-title":"J. Biol. Chem"},{"key":"2024010622541640000_JOCES_111_7_1005C25","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1002\/(SICI)1097-0177(199606)206:2&lt;201::AID-AJA9&gt;3.0.CO;2-M","article-title":"Regulated expression of cadherin-11 in human epithelial cells: a role for cadherin-11 in trophoblast-endometrium interactions?","volume":"206","author":"MacCalman","year":"1996","journal-title":"Dev. Dynam"},{"key":"2024010622541640000_JOCES_111_7_1005C26","first-page":"451","article-title":"Cancer metastasis: negative regulation by an invasion-suppressor complex","volume":"19","author":"Mareel","year":"1995","journal-title":"Cancer Detection and Prevention"},{"key":"2024010622541640000_JOCES_111_7_1005C27","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/S0074-7696(08)62222-6","article-title":"Cadherin cell adhesion molecules in differentiation and embryogenesis","volume":"165","author":"Marrs","year":"1996","journal-title":"Int. Rev. Cytol"},{"key":"2024010622541640000_JOCES_111_7_1005C28","doi-asserted-by":"publisher","first-page":"7274","DOI":"10.1073\/pnas.85.19.7274","article-title":"Construction of epithelioid sheets by transfection of mouse sarcoma cells with cDNAs for chicken cell adhesion molecules","volume":"85","author":"Mege","year":"1988","journal-title":"Proc. Nat. Acad Sci USA"},{"key":"2024010622541640000_JOCES_111_7_1005C29","doi-asserted-by":"publisher","first-page":"25272539","DOI":"10.1101\/gad.10.20.2527","article-title":"Signal transduction through \u03b2-catenin and specification of cell fate during embryogenesis","volume":"10","author":"Miller","year":"1996","journal-title":"Genes Dev"},{"key":"2024010622541640000_JOCES_111_7_1005C30","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1083\/jcb.139.1.229","article-title":"Analysis of the signaling activities of localization mutants of \u03b2-catenin during axis specification in Xenopus","volume":"139","author":"Miller","year":"1997","journal-title":"J. Cell Biol"},{"key":"2024010622541640000_JOCES_111_7_1005C31","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1016\/S0092-8674(00)80112-9","article-title":"Xtcf-3 transcription factor mediates \u03b2-catenin-induced axis formation in Xenopus embryos","volume":"86","author":"Moolenaar","year":"1996","journal-title":"Cell"},{"key":"2024010622541640000_JOCES_111_7_1005C32","doi-asserted-by":"publisher","first-page":"3046","DOI":"10.1073\/pnas.92.7.3046","article-title":"Regulation of intracellular \u03b2-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein","volume":"92","author":"Munemitsu","year":"1995","journal-title":"Proc. Nat. Acad. Sci. USA"},{"key":"2024010622541640000_JOCES_111_7_1005C33","doi-asserted-by":"publisher","first-page":"3679","DOI":"10.1002\/j.1460-2075.1988.tb03249.x","article-title":"Cell binding function of E-cadherin is regulated by the cytoplasmic domain","volume":"7","author":"Nagafuchi","year":"1988","journal-title":"EMBO J"},{"key":"2024010622541640000_JOCES_111_7_1005C34","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1083\/jcb.127.1.235","article-title":"The roles of catenins in cadherin-mediated cell adhesion: functional analysis of E-cadherin-\u03b1-catenin fusion molecules","volume":"127","author":"Nagafuchi","year":"1994","journal-title":"J. Cell Biol"},{"key":"2024010622541640000_JOCES_111_7_1005C35","doi-asserted-by":"publisher","first-page":"1341","DOI":"10.1083\/jcb.125.6.1341","article-title":"Defining interactions and distributions of cadherin and catenin complexes in polarized epithelial cells","volume":"125","author":"Nathke","year":"1994","journal-title":"J. Cell Biol"},{"key":"2024010622541640000_JOCES_111_7_1005C36","doi-asserted-by":"publisher","first-page":"1345","DOI":"10.1093\/carcin\/12.7.1345","article-title":"Expression of E-cadherin, P-cadherin and involucrin by normal and neoplastic keratinocytes in culture","volume":"12","author":"Nicholson","year":"1991","journal-title":"Carcinogenesis"},{"key":"2024010622541640000_JOCES_111_7_1005C37","doi-asserted-by":"publisher","first-page":"2649","DOI":"10.1083\/jcb.103.6.2649","article-title":"A novel cadherin in cell adhesion molecule: its expression patterns associated with implantation and organogenesis of mouse embryos","volume":"103","author":"Nose","year":"1986","journal-title":"J. Cell Biol"},{"key":"2024010622541640000_JOCES_111_7_1005C38","doi-asserted-by":"publisher","first-page":"993","DOI":"10.1016\/0092-8674(88)90114-6","article-title":"Expressed recombinant cadherins mediate cell sorting in model systems","volume":"54","author":"Nose","year":"1988","journal-title":"Cell"},{"key":"2024010622541640000_JOCES_111_7_1005C39","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/0092-8674(90)90222-Z","article-title":"Localization of specificity determining sites in cadherin cell adhesion molecules","volume":"61","author":"Nose","year":"1990","journal-title":"Cell"},{"key":"2024010622541640000_JOCES_111_7_1005C40","doi-asserted-by":"publisher","first-page":"989","DOI":"10.1083\/jcb.116.4.989","article-title":"Molecular organization of the uvomorulin-catenin complex","volume":"116","author":"Ozawa","year":"1992","journal-title":"J. Cell Biol"},{"key":"2024010622541640000_JOCES_111_7_1005C41","doi-asserted-by":"publisher","first-page":"1033","DOI":"10.1016\/0092-8674(90)90506-A","article-title":"Single amino acid substitutions in one Ca2+ binding site of uvomorulin abolishes the adhesive function","volume":"63","author":"Ozawa","year":"1990","journal-title":"Cell"},{"key":"2024010622541640000_JOCES_111_7_1005C42","doi-asserted-by":"publisher","first-page":"4536","DOI":"10.1016\/S0021-9258(19)67326-6","article-title":"Regulation of complexed and free catenin pools by distinct mechanisms: differential effects of Wnt-1 and v-Src","volume":"272","author":"Papkoff","year":"1997","journal-title":"J. Biol. Chem"},{"key":"2024010622541640000_JOCES_111_7_1005C43","doi-asserted-by":"publisher","first-page":"2128","DOI":"10.1128\/MCB.16.5.2128","article-title":"Wnt-1 regulates free pools of catenins and stabilizes APC-catenin complexes","volume":"16","author":"Papkoff","year":"1996","journal-title":"Mol. Cell. Biol"},{"key":"2024010622541640000_JOCES_111_7_1005C44","doi-asserted-by":"crossref","DOI":"10.1002\/(SICI)1097-0169(1998)40:1<87::AID-CM8>3.0.CO;2-C","article-title":"Plakoglobin induces desmosome formation and epidermoid phenotype in N-cadherin-expressing squamous carcinoma cells deficient in plakoglobin in E-cadherin","volume-title":"Cell Motil. Cytoskel. (in press)","author":"Parker","year":"1998"},{"key":"2024010622541640000_JOCES_111_7_1005C45","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1093\/oso\/9780199633197.003.0009","article-title":"Biochemical approaches for analyzing de novo assembly of epithelial junctional components","volume-title":"Cell-Cell Interactions, A Practical Approach","author":"Pasdar","year":"1992"},{"key":"2024010622541640000_JOCES_111_7_1005C46","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1002\/cm.970300203","article-title":"Desmosome assembly and disassembly are regulated by reversible protein phosphorylation in cultured epithelial cells","volume":"30","author":"Pasdar","year":"1995","journal-title":"Cell Motil. Cytoskel"},{"key":"2024010622541640000_JOCES_111_7_1005C47","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1016\/S0962-8924(00)89015-7","article-title":"Cell adhesion and signal transduction: the armadillo connection","volume":"5","author":"Peifer","year":"1995","journal-title":"Trends Cell Biol"},{"key":"2024010622541640000_JOCES_111_7_1005C48","doi-asserted-by":"publisher","first-page":"974","DOI":"10.1126\/science.272.5264.974","article-title":"Regulating cell proliferation: as easy as APC","volume":"272","author":"Peifer","year":"1996","journal-title":"Science"},{"key":"2024010622541640000_JOCES_111_7_1005C49","doi-asserted-by":"publisher","first-page":"681","DOI":"10.1083\/jcb.118.3.681","article-title":"The vertebrate adhesive junction proteins beta-catenin and plakoglobin and the Drosophila segment polarity gene armadillo form a multigene family with similar properties","volume":"118","author":"Peifer","year":"1992","journal-title":"J. Cell Biol"},{"key":"2024010622541640000_JOCES_111_7_1005C50","doi-asserted-by":"publisher","first-page":"751","DOI":"10.1242\/jcs.104.3.751","article-title":"Defining E-cadherin associated protein complexes in epithelial cells: plakoglobin, \u03b2-catenin and g-catenin are distinct components","volume":"104","author":"Piepenhagen","year":"1993","journal-title":"J. Cell Sci"},{"key":"2024010622541640000_JOCES_111_7_1005C51","doi-asserted-by":"publisher","first-page":"5896","DOI":"10.1093\/nar\/18.19.5896","article-title":"Human N-cadherin: nucleotide and deduced amino acid sequence","volume":"18","author":"Reid","year":"1990","journal-title":"Nucleic Acids Res"},{"key":"2024010622541640000_JOCES_111_7_1005C52","doi-asserted-by":"publisher","first-page":"8813","DOI":"10.1073\/pnas.92.19.8813","article-title":"\u03b11-(E) catenin is an actin-binding and -bundling protein mediating the attachment of F-actin to the membrane adhesion complex","volume":"92","author":"Rimm","year":"1995","journal-title":"Proc. Nat. Acad Sci USA"},{"key":"2024010622541640000_JOCES_111_7_1005C53","doi-asserted-by":"publisher","first-page":"20201","DOI":"10.1074\/jbc.270.34.20201","article-title":"Identification of plakoglobin domains required for association with N-cadherin and \u03b1-catenin","volume":"270","author":"Sacco","year":"1996","journal-title":"J. Biol. Chem"},{"key":"2024010622541640000_JOCES_111_7_1005C54","first-page":"2128","article-title":"Cadherin cell-adhesion molecules in human epithelial tissues and carcinomas","volume":"49","author":"Shimoyama","year":"1991","journal-title":"Cancer Res"},{"key":"2024010622541640000_JOCES_111_7_1005C55","first-page":"5770","article-title":"Cadherin dysfunction in a human cancer line: possible involvement of loss of \u03b1-catenin expression in reduced cell-cell adhesiveness","volume":"52","author":"Shimoyama","year":"1992","journal-title":"Cancer Res"},{"key":"2024010622541640000_JOCES_111_7_1005C56","doi-asserted-by":"publisher","first-page":"11356","DOI":"10.1073\/pnas.90.23.11356","article-title":"Identification of the promoter and a transcriptional enhancer of the gene encoding L-CAM, a calcium-dependent cell adhesion molecule","volume":"90","author":"Sorkin","year":"1993","journal-title":"Proc. Nat. Acad Sci USA"},{"key":"2024010622541640000_JOCES_111_7_1005C57","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1016\/0168-9525(87)90238-1","article-title":"Cadherins: a molecular family essential for selective cellcell adhesion and animal morphogenesis","volume":"3","author":"Takeichi","year":"1987","journal-title":"Trends Genet"},{"key":"2024010622541640000_JOCES_111_7_1005C58","doi-asserted-by":"publisher","first-page":"1451","DOI":"10.1126\/science.2006419","article-title":"Cadherin cell adhesion receptors as morphogenetic regulator","volume":"251","author":"Takeichi","year":"1991","journal-title":"Science"},{"key":"2024010622541640000_JOCES_111_7_1005C59","doi-asserted-by":"publisher","first-page":"806","DOI":"10.1016\/0955-0674(93)90029-P","article-title":"Cadherins in cancer: implications for invasion and metastasis","volume":"5","author":"Takeichi","year":"1993","journal-title":"Curr. Opin. Cell Biol"},{"key":"2024010622541640000_JOCES_111_7_1005C60","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1016\/0955-0674(95)80102-2","article-title":"Morphogenetic roles of classic cadherins","volume":"7","author":"Takeichi","year":"1995","journal-title":"Curr. Opin. Cell Biol"},{"key":"2024010622541640000_JOCES_111_7_1005C61","doi-asserted-by":"publisher","first-page":"4350","DOI":"10.1073\/pnas.76.9.4350","article-title":"Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedures and some applications","volume":"76","author":"Towbin","year":"1979","journal-title":"Proc. Nat. Acad Sci USA"},{"key":"2024010622541640000_JOCES_111_7_1005C62","doi-asserted-by":"publisher","first-page":"3393","DOI":"10.1002\/j.1460-2075.1985.tb04095.x","article-title":"Identification of a putative cell adhesion domain of uvomorulin","volume":"4","author":"Vestweber","year":"1985","journal-title":"EMBO J"},{"key":"2024010622541640000_JOCES_111_7_1005C63","doi-asserted-by":"publisher","first-page":"1107","DOI":"10.1016\/S0955-0674(89)80058-4","article-title":"Terminal differentiation of epidermal keratinocytes","volume":"1","author":"Watt","year":"1989","journal-title":"Curr. Opin. Cell Biol"},{"key":"2024010622541640000_JOCES_111_7_1005C64","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1083\/jcb.117.2.415","article-title":"Regulation of keratinocyte intercellular junction organization and epidermal morphogenesis by E cadherin","volume":"117","author":"Wheelock","year":"1992","journal-title":"J. Cell Biol"}],"container-title":["Journal of Cell Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.biologists.com\/jcs\/article-pdf\/111\/7\/1005\/3338431\/joces_111_7_1005.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/journals.biologists.com\/jcs\/article-pdf\/111\/7\/1005\/3338431\/joces_111_7_1005.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,6]],"date-time":"2024-01-06T22:54:27Z","timestamp":1704581667000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.biologists.com\/jcs\/article\/111\/7\/1005\/25624\/L-CAM-expression-induces-fibroblast-epidermoid"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,4,1]]},"references-count":64,"journal-issue":{"issue":"7","published-print":{"date-parts":[[1998,4,1]]}},"URL":"https:\/\/doi.org\/10.1242\/jcs.111.7.1005","relation":{},"ISSN":["0021-9533","1477-9137"],"issn-type":[{"value":"0021-9533","type":"print"},{"value":"1477-9137","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,4,1]]}}}