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A comparative gene expression profiling of WT and FRG1 muscles from young pre-dystrophic mice identified differentially expressed genes in several gene categories and networks that could explain the emerging tissue and myogenic stem-cell defects. Overall, our study provides new insights in the pathways regulated by FRG1 and suggests that muscle-stem cells defects could contribute to the pathology of FRG1 mice.<\/jats:p>","DOI":"10.1242\/jcs.121533","type":"journal-article","created":{"date-parts":[[2013,3,23]],"date-time":"2013-03-23T03:20:45Z","timestamp":1364008845000},"source":"Crossref","is-referenced-by-count":11,"title":["Facioscapulohumeral muscular dystrophy region gene 1 over-expression causes primary defects of myogenic stem cells"],"prefix":"10.1242","author":[{"given":"Alexandros","family":"Xynos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Victoria","family":"Neguembor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta","family":"Caccia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danilo","family":"Licastro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Nonis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clelia","family":"Di Serio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elia","family":"Stupka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davide","family":"Gabellini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"237","published-online":{"date-parts":[[2013,1,1]]},"reference":[{"key":"2021042522044978300_b1","doi-asserted-by":"crossref","first-page":"1859","DOI":"10.1091\/mbc.11.5.1859","article-title":"A role for nitric oxide in muscle repair: nitric oxide-mediated activation of muscle satellite cells.","volume":"11","author":"Anderson","year":"2000","journal-title":"Mol. 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