{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T12:54:01Z","timestamp":1784033641610,"version":"3.55.0"},"reference-count":28,"publisher":"The Company of Biologists","issue":"18","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,9,15]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n               <jats:p>Distortion-product otoacoustic emissions (DPOAEs) in tympanal organs of insects are vulnerable to manipulations that interfere with the animal's physiological state. Starting at a medium temperature, we raised and lowered the locust's body temperature within the range of 12 to 35\u00b0C by changing the temperature of the surrounding air, while recording DPOAEs. These experimental manipulations resulted in reversible amplitude changes of the 2f1\u2013f2 emission, which were dependent on stimulus frequency and level. Using low f2 frequencies of up to 10 kHz, a temperature increase (median +8\u20139\u00b0C) led to an upward shift of DPOAE amplitudes of approximately +10 dB, whereas a temperature decrease (median \u22127\u00b0C) was followed by a reduction of DPOAE amplitudes by 3 to 5 dB. Both effects were only present in the range of the low-level component of DPOAE growth functions below L2 levels (levels of the f2 stimulus) of approximately 30 dB SPL. DPOAEs evoked by higher stimulus levels as well as measurements using higher stimulation frequencies above 10 kHz remained unaffected by any temperature shifts. The Arrhenius activation energy was calculated from the \u221210 dB SPL thresholds (representing the low-level component) of growth functions, which had been measured with 8 and 10 kHz as f2 frequencies and amounted to up to ~34 and 41 kJ mol\u22121, respectively. Such activation energy values provide a hint that the dynein-tubulin system within the scolopidial receptors could play an essential part in the DPOAE generation in tympanal organs.<\/jats:p>","DOI":"10.1242\/jeb.074377","type":"journal-article","created":{"date-parts":[[2012,8,22]],"date-time":"2012-08-22T17:13:26Z","timestamp":1345655606000},"page":"3309-3316","source":"Crossref","is-referenced-by-count":7,"title":["Temperature dependence of distortion-product otoacoustic emissions in tympanal organs of locusts"],"prefix":"10.1242","volume":"215","author":[{"given":"Doreen","family":"M\u00f6ckel","sequence":"first","affiliation":[{"name":"Institut f\u00fcr Zellbiologie und Neurowissenschaft, J. W. Goethe-Universit\u00e4t, Max-von-Laue-Stra\u00dfe 13, D-60438 Frankfurt am Main, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manfred","family":"K\u00f6ssl","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Zellbiologie und Neurowissenschaft, J. 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Physiol."},{"key":"2021042507395043400_R3","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1126\/science.1166541","article-title":"Harmonic convergence in the love songs of the dengue vector mosquito","volume":"323","author":"Cator","year":"2009","journal-title":"Science"},{"key":"2021042507395043400_R4","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/S0378-5955(01)00381-1","article-title":"Components of the 2f1-f2 distortion-product otoacoustic emission in a moth","volume":"162","author":"Coro","year":"2001","journal-title":"Hear. Res."},{"key":"2021042507395043400_R5","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1113\/jphysiol.1989.sp017878","article-title":"Activation and adaptation of transducer currents in turtle hair cells","volume":"419","author":"Crawford","year":"1989","journal-title":"J. Physiol."},{"key":"2021042507395043400_R6","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1038\/nrm730","article-title":"Prestin, a new type of motor protein","volume":"3","author":"Dallos","year":"2002","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"2021042507395043400_R7","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/0166-2236(87)90013-0","article-title":"Electrical tuning of hair cells in the inner ear","volume":"10","author":"Fettiplace","year":"1987","journal-title":"Trends Neurosci."},{"key":"2021042507395043400_R8","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.1242\/jeb.001495","article-title":"Effects of temperature on tuning of the auditory pathway in the cicada Tettigetta josei (Hemiptera, Tibicinidae)","volume":"210","author":"Fonseca","year":"2007","journal-title":"J. Exp. Biol."},{"key":"2021042507395043400_R9","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1098\/rspb.2000.1376","article-title":"Active auditory mechanics in mosquitoes","volume":"268","author":"G\u00f6pfert","year":"2001","journal-title":"Proc. Biol. Sci."},{"key":"2021042507395043400_R10","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1073\/pnas.0405741102","article-title":"Power gain exhibited by motile mechanosensory neurons in Drosophila ears","volume":"102","author":"G\u00f6pfert","year":"2005","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2021042507395043400_R11","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1098\/rstb.1960.0005","article-title":"The fine structure of the insect ear","volume":"243","author":"Gray","year":"1960","journal-title":"Philos. Trans. R. Soc. Lond. B"},{"key":"2021042507395043400_R12","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1002\/(SICI)1097-010X(19990215)283:3<270::AID-JEZ5>3.0.CO;2-C","article-title":"Tympanal receptor cells in Schistocerca gregaria: correlation of soma positions and dendrite attachment sites, central projections and physiologies","volume":"283","author":"Jacobs","year":"1999","journal-title":"J. Exp. Zool."},{"key":"2021042507395043400_R13","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1111\/j.1749-6632.1959.tb56120.x","article-title":"Synchronization of cell division in Amoebae","volume":"78","author":"James","year":"1959","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"2021042507395043400_R14","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1159\/000013805","article-title":"Effect of temperature on the transient evoked and distortion product otoacoustic emissions in rats","volume":"3","author":"Khvoles","year":"1998","journal-title":"Audiol. Neurootol."},{"key":"2021042507395043400_R15","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1121\/1.423258","article-title":"Acoustic distortion products from the ear of a grasshopper","volume":"104","author":"K\u00f6ssl","year":"1998","journal-title":"J. Acoust. Soc. Am."},{"key":"2021042507395043400_R16","doi-asserted-by":"crossref","first-page":"3822","DOI":"10.1121\/1.2363934","article-title":"L1,L2 maps of distortion-product otoacoustic emissions from a moth ear with only two auditory receptor neurons","volume":"120","author":"K\u00f6ssl","year":"2006","journal-title":"J. Acoust. Soc. Am."},{"key":"2021042507395043400_R17","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1007\/s00359-007-0244-8","article-title":"Otoacoustic emissions from insect ears having just one auditory neuron","volume":"193","author":"K\u00f6ssl","year":"2007","journal-title":"J. Comp. Physiol. A"},{"key":"2021042507395043400_R18","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1007\/s00359-008-0344-0","article-title":"Otoacoustic emissions from insect ears: evidence of active hearing?","volume":"194","author":"K\u00f6ssl","year":"2008","journal-title":"J. Comp. Physiol. A"},{"key":"2021042507395043400_R19","doi-asserted-by":"crossref","first-page":"2740","DOI":"10.1121\/1.1479151","article-title":"One source for distortion product otoacoustic emissions generated by low- and high-level primaries","volume":"111","author":"Lukashkin","year":"2002","journal-title":"J. Acoust. Soc. Am."},{"key":"2021042507395043400_R20","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1007\/s10162-006-0039-6","article-title":"Temperature dependence of anuran distortion product otoacoustic emissions","volume":"7","author":"Meenderink","year":"2006","journal-title":"J. Assoc. Res. 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