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We measured changes in: (1) plasma osmolality and prolactin (PRL) levels; (2) pituitary expression of prolactin (PRL) and its receptors, PRLR1 and PRLR2; (3) branchial expression of PRLR1, PRLR2, Na+\/Cl\u2212 co-transporter (NCC), Na+\/K+\/2Cl\u2212 co-transporter (NKCC), \u03b11a and \u03b11b isoforms of Na+\/K+-ATPase (NKA), cystic fibrosis transmembrane conductance regulator (CFTR), aquaporin 3 (AQP3) and Na+\/H+ exchanger 3 (NHE3). Mozambique tilapia reared in a tidal environment successfully adapted to SW while fish reared in FW did not survive a transfer to SW beyond the 6\u2005h sampling. With the exception of CFTR, the change in the expression of ion pumps, transporters and channels was more gradual in fish transferred from tidally changing salinities to SW than in fish transferred from FW to SW. Upon transfer to SW, the increase in CFTR expression was more robust in tidal fish than in FW fish. Tidal and SW fish successfully adapted when transferred to FW. These results suggest that Mozambique tilapia reared in a tidally changing salinity, a condition that more closely represents their natural history, gain an adaptive advantage compared with fish reared in FW when facing a hyperosmotic challenge.<\/jats:p>","DOI":"10.1242\/jeb.112664","type":"journal-article","created":{"date-parts":[[2015,1,24]],"date-time":"2015-01-24T05:23:09Z","timestamp":1422076989000},"page":"731-739","source":"Crossref","is-referenced-by-count":57,"title":["The effects of acute salinity challenges on osmoregulation in Mozambique tilapia reared in a tidally changing salinity"],"prefix":"10.1242","volume":"218","author":[{"given":"Benjamin P.","family":"Moorman","sequence":"first","affiliation":[{"name":"Hawaii Institute of Marine Biology, University of Hawaii, Kaneohe, HI 96744, USA"},{"name":"Department of Molecular Biosciences and Bioengineering, University of Hawaii at Manoa, Honolulu, HI 96822, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darren T.","family":"Lerner","sequence":"additional","affiliation":[{"name":"Hawaii Institute of Marine Biology, University of Hawaii, Kaneohe, HI 96744, USA"},{"name":"University of Hawaii Sea Grant College Program, University of Hawaii at Manoa, Honolulu, HI 96822, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. Gordon","family":"Grau","sequence":"additional","affiliation":[{"name":"Hawaii Institute of Marine Biology, University of Hawaii, Kaneohe, HI 96744, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andre P.","family":"Seale","sequence":"additional","affiliation":[{"name":"Hawaii Institute of Marine Biology, University of Hawaii, Kaneohe, HI 96744, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"237","reference":[{"key":"2021052800134597200_JEB112664C1","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1113\/jphysiol.2002.020818","article-title":"Aquaporin water channels--from atomic structure to clinical medicine","volume":"542","author":"Agre","year":"2002","journal-title":"J. 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