{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T08:48:36Z","timestamp":1789894116999,"version":"4.0.1"},"reference-count":37,"publisher":"The Company of Biologists","issue":"6","license":[{"start":{"date-parts":[[1997,3,15]],"date-time":"1997-03-15T00:00:00Z","timestamp":858384000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.biologists.com\/user-licence-1-1\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1997,3,15]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>Whole-cell recording coupled with biocytin injection revealed four types of interneurons intrinsic to the olfactory lobe (OL) of the spiny lobster Panulirus argus. Each type of neuron had a distinct pattern of arborization within the three anatomically defined regions of OL glomeruli (cap, subcap and base). Type I interneurons innervated all three regions, while types II, III and IV branched only in the cap, subcap and base, respectively. Type I interneurons responded to electrical stimulation of the antennular (olfactory) nerve with a burst of 1\u201320 action potentials and a 1\u201310 s depolarization. Type II (cap) interneurons responded to the same input with a burst of 1\u20133 action potentials followed by a shorter hyperpolarization. Type III (subcap) interneurons responded with a burst of 1\u20136 action potentials followed by a delayed, 0.5\u20134 s depolarization. Type IV (base) interneurons responded with a brief depolarization or a burst of 1\u20133 action potentials followed by a 1 s hyperpolarization. The regionalized arborization and the different response properties of the type II, III and IV interneurons strongly imply that lobster olfactory glomeruli contain functionally distinct regions, a feature that should be useful in understanding the multiple synaptic pathways involved in processing olfactory input.<\/jats:p>","DOI":"10.1242\/jeb.200.6.989","type":"journal-article","created":{"date-parts":[[2021,4,25]],"date-time":"2021-04-25T04:01:08Z","timestamp":1619323268000},"page":"989-1001","source":"Crossref","is-referenced-by-count":27,"title":["Local Interneurons Define Functionally Distinct Regions Within Lobster Olfactory Glomeruli"],"prefix":"10.1242","volume":"200","author":[{"given":"M.","family":"Wachowiak","sequence":"first","affiliation":[{"name":"University of Florida Whitney Laboratory and Department of Neuroscience , , 9505 Ocean Shore Boulevard, St Augustine, FL 32086, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. E.","family":"Diebel","sequence":"additional","affiliation":[{"name":"University of Florida Whitney Laboratory and Department of Neuroscience , , 9505 Ocean Shore Boulevard, St Augustine, FL 32086, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B. W.","family":"Ache","sequence":"additional","affiliation":[{"name":"University of Florida Whitney Laboratory and Department of Neuroscience , , 9505 Ocean Shore Boulevard, St Augustine, FL 32086, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"237","published-online":{"date-parts":[[1997,3,15]]},"reference":[{"key":"2024032323223573100_JEXBIO_200_6_989C1","first-page":"3","article-title":"Phylogeny of smell and taste","volume-title":"Smell and Taste in Health and Disease","author":"Ache","year":"1991"},{"key":"2024032323223573100_JEXBIO_200_6_989C2","doi-asserted-by":"publisher","first-page":"1457","DOI":"10.1177\/40.10.1527370","article-title":"Biotin amplification of biotin and horseradish peroxidase signals in histochemical stains","volume":"40","author":"Adams","year":"1992","journal-title":"J. Histochem. Cytochem."},{"key":"2024032323223573100_JEXBIO_200_6_989C3","doi-asserted-by":"publisher","first-page":"493","DOI":"10.2307\/1548686","article-title":"Structure of the brain and medulla terminalis of the spiny lobster Panulirus argus and the crayfish Procambarus clarkii, with an emphasis on olfactory centers","volume":"8","author":"Blaustein","year":"1988","journal-title":"J. Crust. Biol."},{"key":"2024032323223573100_JEXBIO_200_6_989C4","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/978-3-642-75127-1_13","article-title":"Olfactory bulb and antennal lobe","volume-title":"Chemosensory Information Processing","author":"Boeckh","year":"1990"},{"key":"2024032323223573100_JEXBIO_200_6_989C5","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1007\/BF00193512","article-title":"Local interneurons and information processing in the olfactory glomeruli of the moth Manduca sexta","volume":"173","author":"Christensen","year":"1993","journal-title":"J. comp. Physiol. A"},{"key":"2024032323223573100_JEXBIO_200_6_989C6","doi-asserted-by":"publisher","first-page":"905","DOI":"10.1016\/0306-4522(93)90136-4","article-title":"GABAergic control of odour-induced activity in the frog olfactory bulb: Possible GABAergic modulation of granule cell inhibitory action","volume":"56","author":"Duchamp-Viret","year":"1993","journal-title":"Neurosci."},{"key":"2024032323223573100_JEXBIO_200_6_989C7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/BF00217877","article-title":"A neuroanatomical study on the organization of the central antennal pathways in insects. III. Neuroanatomical characterization of physiologically defined response types of deutocerebral neurons in Periplaneta americana","volume":"229","author":"Ernst","year":"1983","journal-title":"Cell Tissue Res"},{"key":"2024032323223573100_JEXBIO_200_6_989C8","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1093\/chemse\/18.2.101","article-title":"Morphology and spatial distribution of bee antennal lobe interneurones responsive to odours","volume":"18","author":"Fonta","year":"1993","journal-title":"Chem. Senses"},{"key":"2024032323223573100_JEXBIO_200_6_989C9","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1016\/0040-8166(91)90052-U","article-title":"A quantitative ultrastructural study of the honeybee antennal lobe","volume":"23","author":"Gascuel","year":"1991","journal-title":"Tissue & Cell"},{"key":"2024032323223573100_JEXBIO_200_6_989C10","first-page":"1184","article-title":"Subcompartmental organization of the rat olfactory bulb glomerulus","volume":"21","author":"Greer","year":"1995","journal-title":"Neurosci. Abstr."},{"key":"2024032323223573100_JEXBIO_200_6_989C11","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1002\/cne.903370211","article-title":"Terminal arborizations of olfactory nerve fibers in the glomeruli of the olfactory bulb","volume":"337","author":"Halasz","year":"1993","journal-title":"J. comp. Neurol"},{"key":"2024032323223573100_JEXBIO_200_6_989C12","doi-asserted-by":"publisher","first-page":"1313","DOI":"10.1126\/science.1598574","article-title":"Functional specialization of olfactory glomeruli in a moth","volume":"256","author":"Hansson","year":"1992","journal-title":"Science"},{"key":"2024032323223573100_JEXBIO_200_6_989C13","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1073\/pnas.92.1.67","article-title":"Analysis of chemical signals by nervous systems","volume":"92","author":"Hildebrand","year":"1995","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"2024032323223573100_JEXBIO_200_6_989C14","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1007\/BF00318481","article-title":"Distribution of acetylcholinesterase activity in the deutocerebrum of the sphinx moth Manduca sexta","volume":"279","author":"Homberg","year":"1995","journal-title":"Cell Tissue Res"},{"key":"2024032323223573100_JEXBIO_200_6_989C15","doi-asserted-by":"publisher","first-page":"670","DOI":"10.1073\/pnas.79.2.670","article-title":"Mapping of odor-related neuronal activity in the olfactory bulb by high-resolution 2-deoxyglucose autoradiography","volume":"79","author":"Lancet","year":"1982","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"2024032323223573100_JEXBIO_200_6_989C16","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1002\/cne.903050215","article-title":"Inventory and distribution of synapses of identified uniglomerular projection neurons in the antennal lobe of Periplaneta americana","volume":"305","author":"Malun","year":"1991","journal-title":"J. comp. Neurol."},{"key":"2024032323223573100_JEXBIO_200_6_989C17","first-page":"249","article-title":"Olfactory mechanisms in the moth Manduca sexta: response characteristics and morphology of central neurons in the antennal lobes","volume":"213","author":"Matsumoto","year":"1981","journal-title":"Proc. R. Soc. Lond."},{"key":"2024032323223573100_JEXBIO_200_6_989C18","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1007\/BF00243398","article-title":"Identification of three classes of multiglomerular, broad-spectrum neurons in the crayfish olfactory midbrain by correlated patterns of electrical activity and dendritic arborization","volume":"177","author":"Mellon","year":"1994","journal-title":"J. comp. Physiol. A"},{"key":"2024032323223573100_JEXBIO_200_6_989C19","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/0165-0270(87)90010-0","article-title":"Bubble pressure measurement of micropipet tip outer diameter","volume":"22","author":"Mittman","year":"1987","journal-title":"J. Neurosci. Meth."},{"key":"2024032323223573100_JEXBIO_200_6_989C20","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1242\/jcs.9.2.347","article-title":"The neuropil of the glomeruli of the olfactory bulb","volume":"9","author":"Pinching","year":"1971","journal-title":"J. Cell Sci."},{"key":"2024032323223573100_JEXBIO_200_6_989C21","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1016\/0092-8674(94)90015-9","article-title":"Information coding in the olfactory system: Evidence for a stereotyped and highly organized epitope map in the olfactory bulb","volume":"79","author":"Ressler","year":"1994","journal-title":"Cell"},{"key":"2024032323223573100_JEXBIO_200_6_989C22","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1007\/BF00306703","article-title":"The structural organization of glomerular neuropile in the olfactory and accessory lobes of an Australian freshwater crayfish, Cherax destructor","volume":"142","author":"Sandeman","year":"1973","journal-title":"Z. Zellforsch. mikrosk. Anat."},{"key":"2024032323223573100_JEXBIO_200_6_989C23","doi-asserted-by":"publisher","first-page":"304","DOI":"10.2307\/1542217","article-title":"Morphology of the brain of crayfish, crabs and spiny lobsters: A common nomenclature for homologous structures","volume":"183","author":"Sandeman","year":"1992","journal-title":"Biol. Bull. mar. biol. Lab., Woods Hole"},{"key":"2024032323223573100_JEXBIO_200_6_989C24","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1016\/S0006-3495(92)81875-1","article-title":"Significance of glomerular compartmentalization for olfactory coding","volume":"61","author":"Schild","year":"1992","journal-title":"Biophys. J."},{"key":"2024032323223573100_JEXBIO_200_6_989C25","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1002\/cne.903180305","article-title":"Antennular projections to the midbrain of the spiny lobster. II. Sensory innervation of the olfactory lobe","volume":"318","author":"Schmidt","year":"1992","journal-title":"J. comp. Neurol."},{"key":"2024032323223573100_JEXBIO_200_6_989C26","article-title":"Processing of antennular input in the brain of the spiny lobster, Panulirus argus. II. The olfactory pathway","volume-title":"J. comp. Physiol. A (in press)","author":"Schmidt","year":"1996"},{"key":"2024032323223573100_JEXBIO_200_6_989C27","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1002\/(SICI)1097-4695(199605)30:1&lt;123::AID-NEU11&gt;3.0.CO;2-N","article-title":"Functional organization of olfactory system","volume":"30","author":"Shipley","year":"1996","journal-title":"J. Neurobiol."},{"key":"2024032323223573100_JEXBIO_200_6_989C28","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1002\/cne.903380103","article-title":"Ramification pattern and ultrastructural characteristics of the serotonin-immunoreactive neuron in the antennal lobe of the moth Manduca sexta: A laser scanning confocal and electron microscopic study","volume":"338","author":"Sun","year":"1993","journal-title":"J. comp. Neurol."},{"key":"2024032323223573100_JEXBIO_200_6_989C29","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1002\/cne.903110106","article-title":"Light microscopic Golgi study of mitral\/tufted cells in the accessory olfactory bulb of the adult rat","volume":"311","author":"Takami","year":"1991","journal-title":"J. comp. Neurol."},{"key":"2024032323223573100_JEXBIO_200_6_989C30","first-page":"279","article-title":"Organization and synaptic ultrastructure of glomeruli in the antennal lobes of the moth Manduca sexta: a study using thin sections and freeze\u2013fracture","volume":"213","author":"Tolbert","year":"1981","journal-title":"Proc. R. Soc. Lond."},{"key":"2024032323223573100_JEXBIO_200_6_989C31","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1007\/BF00217435","article-title":"Morphology and physiology of multiglomerular olfactory projection neurons in the spiny lobster","volume":"175","author":"Wachowiak","year":"1994","journal-title":"J. comp. Physiol. A"},{"key":"2024032323223573100_JEXBIO_200_6_989C32","doi-asserted-by":"crossref","DOI":"10.1007\/s003590050055","article-title":"Dual inhibitory pathways mediated by GABA- and histaminergic interneurons in the lobster olfactory lobe","volume-title":"J. comp. Physiol. A (in press)","author":"Wachowiak","year":"1997"},{"key":"2024032323223573100_JEXBIO_200_6_989C33","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1007\/BF00188163","article-title":"Functional organization of olfactory processing in the accessory lobe of the spiny lobster","volume":"178","author":"Wachowiak","year":"1996","journal-title":"J. comp. Physiol. A"},{"key":"2024032323223573100_JEXBIO_200_6_989C34","doi-asserted-by":"publisher","first-page":"932","DOI":"10.1152\/jn.1990.64.3.932","article-title":"Intracellular responses of identified rat olfactory bulb interneurons to electrical and odor stimulation","volume":"64","author":"Wellis","year":"1990","journal-title":"J. Neurophysiol."},{"key":"2024032323223573100_JEXBIO_200_6_989C35","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/0006-8993(72)90346-0","article-title":"Synaptic organization in the olfactory glomerulus of the mouse","volume":"37","author":"White","year":"1972","journal-title":"Brain Res."},{"key":"2024032323223573100_JEXBIO_200_6_989C36","doi-asserted-by":"publisher","first-page":"1837","DOI":"10.1523\/JNEUROSCI.11-06-01837.1991","article-title":"Local information processing in dendritic trees: Subsets of spines in granule cells of the mammalian olfactory bulb","volume":"11","author":"Woolf","year":"1991","journal-title":"J. Neurosci."},{"key":"2024032323223573100_JEXBIO_200_6_989C37","doi-asserted-by":"publisher","first-page":"3371","DOI":"10.1073\/pnas.92.8.3371","article-title":"Refinement of odor molecule tuning by dendrodendritic synaptic inhibition in the olfactory bulb","volume":"92","author":"Yokoi","year":"1995","journal-title":"Proc. natn. Acad. Sci. U.S.A."}],"container-title":["Journal of Experimental Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.biologists.com\/jeb\/article-pdf\/200\/6\/989\/3404332\/jexbio_200_6_989.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/journals.biologists.com\/jeb\/article-pdf\/200\/6\/989\/3404332\/jexbio_200_6_989.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,23]],"date-time":"2024-03-23T23:23:35Z","timestamp":1711236215000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.biologists.com\/jeb\/article\/200\/6\/989\/7206\/Local-Interneurons-Define-Functionally-Distinct"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,3,15]]},"references-count":37,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1997,3,15]]}},"URL":"https:\/\/doi.org\/10.1242\/jeb.200.6.989","relation":{},"ISSN":["0022-0949","1477-9145"],"issn-type":[{"value":"0022-0949","type":"print"},{"value":"1477-9145","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,3,15]]}}}