{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T16:56:38Z","timestamp":1774457798513,"version":"3.50.1"},"reference-count":42,"publisher":"The Company of Biologists","issue":"7","license":[{"start":{"date-parts":[[2000,4,1]],"date-time":"2000-04-01T00:00:00Z","timestamp":954547200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.biologists.com\/user-licence-1-1\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2000,4,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>This study examined the location and physiological roles of branchial chemoreceptors involved in the cardiorespiratory responses to hypoxia and hypercarbia in a neotropical fish that exhibits aquatic surface respiration, the tambaqui (Colossoma macropomum). Fish were exposed to abrupt progressive environmental hypoxia (18.6\u20131.3 kPa water ) and hypercarbia (water equilibrated with 5 % CO2 in air, which lowered the water pH from 7.0 to 5.0). They were also subjected to injections of NaCN into the ventral aorta (to stimulate receptors monitoring the blood) and buccal cavity (to stimulate receptors monitoring the respiratory water). All tests were performed before and after selective denervation of branchial branches of cranial nerves IX and X to the gill arches. The data suggest that the O2 receptors eliciting reflex bradycardia and increases in breathing frequency are situated on all gill arches and sense changes in both the blood and respiratory water and that the O2 receptors triggering the elevation in systemic vascular resistance, breathing amplitude, swelling of the inferior lip and that induce aquatic surface respiration during hypoxia are extrabranchial, although branchial receptors also contribute to the latter two responses. Hypercarbia also produced bradycardia and increases in breathing frequency, as well as hypertension, and, while the data suggest that there may be receptors uniquely sensitive to changes in CO2\/pH involved in cardiorespiratory control, this is based on quantitative rather than qualitative differences in receptor responses. These data reveal yet another novel combination for the distribution of cardiorespiratory chemoreceptors in fish from which teleologically satisfying trends have yet to emerge.<\/jats:p>","DOI":"10.1242\/jeb.203.7.1225","type":"journal-article","created":{"date-parts":[[2021,4,25]],"date-time":"2021-04-25T05:42:08Z","timestamp":1619329328000},"page":"1225-1239","source":"Crossref","is-referenced-by-count":120,"title":["Branchial Receptors and Cardiorespiratory Reflexes in A Neotropical Fish, The Tambaqui (<i>Colossoma Macropomum<\/i>)"],"prefix":"10.1242","volume":"203","author":[{"given":"Lena","family":"Sundin","sequence":"first","affiliation":[{"name":"University of British Columbia 1 Department of Zoology , , 6270 University Boulevard, Vancouver, British Columbia, Canada V6T 1Z4"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen G.","family":"Reid","sequence":"additional","affiliation":[{"name":"University of British Columbia 1 Department of Zoology , , 6270 University Boulevard, Vancouver, British Columbia, Canada V6T 1Z4"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F. Tadeu","family":"Rantin","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Carlos 2 Department of Physiological Sciences, Federal , 13565-905 S\u00e3o Carlos, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William K.","family":"Milsom","sequence":"additional","affiliation":[{"name":"University of British Columbia 1 Department of Zoology , , 6270 University Boulevard, Vancouver, British Columbia, Canada V6T 1Z4"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"237","reference":[{"key":"2024121804062030300_JEXBIO_203_7_1225C1","first-page":"869","article-title":"Morphological adaptation of two Amazonian characoids (Pisces) for surviving in oxygen deficient waters","volume":"67","author":"Braum","year":"1982","journal-title":"Int. Rev. Ges. 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